{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:19:30Z","timestamp":1761016770271,"version":"build-2065373602"},"reference-count":17,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T00:00:00Z","timestamp":1228089600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":1689,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure"],"published-print":{"date-parts":[[2008,12]]},"DOI":"10.1016\/j.seizure.2008.05.008","type":"journal-article","created":{"date-parts":[[2008,6,19]],"date-time":"2008-06-19T04:51:44Z","timestamp":1213851104000},"page":"744-747","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Epileptic seizures as the sole manifestation of neuro-Beh\u00e7et's disease: Complete control under interferon-alpha treatment"],"prefix":"10.1016","volume":"17","author":[{"given":"Elisabeth","family":"Chroni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Monastirli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panayiotis","family":"Polychronopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efi","family":"Pasmatzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophia","family":"Georgiou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleftheria","family":"Vryzaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dionysios","family":"Tsambaos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2008.05.008_bib1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/01.nrl.0000156343.16797.c4","article-title":"Neuro-Beh\u00e7et disease: a review","volume":"11","author":"Haghighi","year":"2005","journal-title":"Neurologist"},{"key":"10.1016\/j.seizure.2008.05.008_bib2","first-page":"1078","article-title":"Criteria for the diagnosis of Beh\u00e7et\u2019 disease","volume":"335","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.seizure.2008.05.008_bib3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s10238-004-0045-0","article-title":"Beh\u00e7et's disease","volume":"4","author":"Al-Mutawa","year":"2004","journal-title":"Clin Exp Med"},{"key":"10.1016\/j.seizure.2008.05.008_bib4","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1111\/j.1468-1331.2006.01613.x","article-title":"Neuro-Beh\u00e7et's disease in Caucasians: a study of 22 patients","volume":"14","author":"Joseph","year":"2007","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.seizure.2008.05.008_bib5","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1046\/j.1528-1157.2002.01102.x","article-title":"Epileptic seizures in Beh\u00e7et disease","volume":"43","author":"Aykutlu","year":"2002","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2008.05.008_bib6","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1136\/jnnp.68.3.392","article-title":"Beh\u00e7et's syndrome may present with partial seizures","volume":"68","author":"Mead","year":"2000","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.seizure.2008.05.008_bib7","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.clineuro.2004.12.021","article-title":"Epilepsia partialis continua in a patient with Beh\u00e7et's disease","volume":"108","author":"Aktekin","year":"2006","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.seizure.2008.05.008_bib8","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1552-6569.2002.tb00144.x","article-title":"Decreased cerebral blood flow in neuro-Beh\u00e7et's syndrome patients with neuropsychiatric manifestations and normal magnetic resonance imaging: a preliminary report","volume":"12","author":"Huang","year":"2002","journal-title":"J Neuroimaging"},{"key":"10.1016\/j.seizure.2008.05.008_bib9","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/BF00407749","article-title":"Beh\u00e7et's syndrome: treatment with recombinant leukocyte alpha-interferon","volume":"278","author":"Tsambaos","year":"1986","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.seizure.2008.05.008_bib10","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1046\/j.1365-2796.1998.00159.x","article-title":"Efficacy and safety of systemic recombinant interferon-alpha in Beh\u00e7et's disease","volume":"243","author":"Georgiou","year":"1998","journal-title":"J Int Med"},{"key":"10.1016\/j.seizure.2008.05.008_bib11","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.semarthrit.2003.09.010","article-title":"The use of interferon \u03b1 in Beh\u00e7et disease: review of the literature","volume":"33","author":"K\u00f6tter","year":"2004","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.seizure.2008.05.008_bib12","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/00041327-200106000-00011","article-title":"Interferon-alpha 2a treatment of neuro-Beh\u00e7et disease","volume":"21","author":"Nichols","year":"2001","journal-title":"J Neuroophthalmol"},{"key":"10.1016\/j.seizure.2008.05.008_bib13","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1212\/01.WNL.0000123695.22623.32","article-title":"Efficacy and tolerability of the new antiepileptic drugs II. Treatment of refractory epilepsy","volume":"62","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2008.05.008_bib14","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/S0090-9556(24)15285-3","article-title":"In vitro evaluation of potential drug interactions with levetiracetam, a new antiepileptic agent","volume":"27","author":"Nicolas","year":"1999","journal-title":"Drug Metab Dispos"},{"key":"10.1016\/j.seizure.2008.05.008_bib15","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0074-7742(06)81015-9","article-title":"Risk and predictability of drug interactions in the elderly","volume":"81","author":"Levy","year":"2007","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.seizure.2008.05.008_bib16","first-page":"2480","article-title":"Differential effect of IFNalpha-2b on the cytochrome P450 enzyme system: a potential basis of IFN toxicity and its modulation by other drugs","volume":"8","author":"Islam","year":"2002","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.seizure.2008.05.008_bib17","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1111\/j.0013-9580.2003.06203.x","article-title":"Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate.","volume":"44","author":"Nallani","year":"2003","journal-title":"Epilepsia"}],"container-title":["Seizure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131108001088?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131108001088?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T01:36:55Z","timestamp":1761010615000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1059131108001088"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,12]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,12]]}},"alternative-id":["S1059131108001088"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2008.05.008","relation":{},"ISSN":["1059-1311"],"issn-type":[{"type":"print","value":"1059-1311"}],"subject":[],"published":{"date-parts":[[2008,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epileptic seizures as the sole manifestation of neuro-Beh\u00e7et's disease: Complete control under interferon-alpha treatment","name":"articletitle","label":"Article Title"},{"value":"Seizure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2008.05.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}