{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T13:03:49Z","timestamp":1772024629252,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":1050,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100004330","name":"GlaxoSmithKline","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100004330","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1016\/j.seizure.2010.06.014","type":"journal-article","created":{"date-parts":[[2010,7,22]],"date-time":"2010-07-22T06:58:56Z","timestamp":1279781936000},"page":"432-438","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Quality of life and treatment satisfaction in Spanish epilepsy patients on monotherapy with lamotrigine or valproic acid"],"prefix":"10.1016","volume":"19","author":[{"given":"C.","family":"Viteri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Codina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Cobaleda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Lahuerta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Barriga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.D.","family":"Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2010.06.014_bib1","series-title":"Epilepsy. Fact sheets no. 999","author":"World Health Organization","year":"2009"},{"key":"10.1016\/j.seizure.2010.06.014_bib2","first-page":"664","article-title":"Epidemiology of epilepsy","volume":"82","author":"Sridharan","year":"2002","journal-title":"Curr Sci"},{"key":"10.1016\/j.seizure.2010.06.014_bib3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.yebeh.2003.08.033","article-title":"Lamotrigine monotherapy compared with carbamazepine, phenytoin, or valproate monotherapy in patients with epilepsy","volume":"4","author":"Kaminow","year":"2003","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.06.014_bib4","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1111\/j.1528-1167.2005.51204.x","article-title":"Gender differences in epilepsy","volume":"46","author":"Christensen","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.06.014_bib5","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0074-7742(08)00003-2","article-title":"Hormonal influences on seizures: basic neurobiology","volume":"83","author":"Frye","year":"2008","journal-title":"Int Rev Neurobiol"},{"key":"10.1016\/j.seizure.2010.06.014_bib6","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1053\/seiz.1999.0295","article-title":"Best practice guidelines for the management of women with epilepsy. The Women with Epilepsy Guidelines Development Group","volume":"8","author":"Crawford","year":"1999","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2010.06.014_bib7","doi-asserted-by":"crossref","first-page":"695","DOI":"10.2165\/00023210-200216100-00004","article-title":"Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience","volume":"16","author":"Perucca","year":"2002","journal-title":"CNS Drugs"},{"key":"10.1016\/j.seizure.2010.06.014_bib8","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1136\/bmj.318.7176.106","article-title":"Fortnightly review: drug treatment of epilepsy","volume":"318","author":"Feely","year":"1999","journal-title":"BMJ"},{"key":"10.1016\/j.seizure.2010.06.014_bib9","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.seizure.2006.11.009","article-title":"Improvement in quality of life after initiation of lamotrigine therapy in patients with epilepsy in a naturalistic treatment setting","volume":"16","author":"Allain","year":"2007","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2010.06.014_bib10","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1006\/ebeh.2001.0168","article-title":"A systematic review of the effects of lamotrigine on cognitive function and quality of life","volume":"2","author":"Aldenkamp","year":"2001","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.06.014_bib11","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1111\/j.1528-1157.1997.tb01252.x","article-title":"Safety of long-term lamotrigine in epilepsy","volume":"38","author":"Mackay","year":"1997","journal-title":"Epilepsia"},{"issue":"Suppl. 7","key":"10.1016\/j.seizure.2010.06.014_bib12","first-page":"S22","article-title":"Lamotrigine-induced severe cutaneous adverse reactions","volume":"39","author":"Schlienger","year":"1998","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.06.014_bib13","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1528-1157.2000.tb01510.x","article-title":"Health status of people with epilepsy compared with a general reference population","volume":"41","author":"Stavem","year":"2000","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.06.014_bib14","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.seizure.2006.10.011","article-title":"Factors influencing on quality of life in people with epilepsy","volume":"16","author":"Guekht","year":"2007","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2010.06.014_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/j.1875-9114.1996.tb02911.x","article-title":"The health status of adults with epilepsy compared with that of people without chronic conditions","volume":"16","author":"Wagner","year":"1996","journal-title":"Pharmacotherapy"},{"key":"10.1016\/j.seizure.2010.06.014_bib16","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short form health survey (SF-36)","volume":"30","author":"Ware","year":"1992","journal-title":"Med Care"},{"key":"10.1016\/j.seizure.2010.06.014_bib17","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/j.1528-1157.1999.tb00861.x","article-title":"The Spanish version of the Quality of Life in Epilepsy Inventory (QOLIE-31): translation, validity, and reliability","volume":"40","author":"Torres","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.06.014_bib18","first-page":"157","article-title":"Validaci\u00f3n de la versi\u00f3n espa\u00f1ola del cuestionario de calidad de vida en epilepsia QOLIE-10","volume":"23","author":"Viteri","year":"2008","journal-title":"Neurolog\u00eda"},{"key":"10.1016\/j.seizure.2010.06.014_bib19","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S1525-5050(03)00004-0","article-title":"Maintenance of improvement in health-related quality of life during long-term treatment with levetiracetam","volume":"4","author":"Cramer","year":"2003","journal-title":"Epilepsy Behav"},{"issue":"Suppl. 6","key":"10.1016\/j.seizure.2010.06.014_bib20","first-page":"S3","article-title":"Clinical experience with new antiepileptic drugs: antiepileptic drugs in Europe","volume":"40","author":"Loiseau","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.06.014_bib21","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.seizure.2005.09.011","article-title":"The LAM-SAFE Study: lamotrigine versus carbamazepine or valproic acid in newly diagnosed focal and generalised epilepsies in adolescents and adults","volume":"14","author":"Steinhoff","year":"2005","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2010.06.014_bib22","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/S1525-5050(02)00046-X","article-title":"Lamotrigine monotherapy improves health-related quality of life in epilepsy: a double-blind comparison with valproate","volume":"3","author":"Sackellares","year":"2002","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.06.014_bib23","first-page":"18","article-title":"Evaluation of the factors affecting the quality of life and total costs in epilepsy patients on monotherapy with carbamazepine and valproate","volume":"50","author":"Balabanov","year":"2008","journal-title":"Folia Med (Plovdiv)"},{"key":"10.1016\/j.seizure.2010.06.014_bib24","doi-asserted-by":"crossref","DOI":"10.3310\/hta11370","article-title":"A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial","volume":"11","author":"Marson","year":"2007","journal-title":"Health Technol Assess"},{"key":"10.1016\/j.seizure.2010.06.014_bib25","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1059131102002546","article-title":"Psychosocial reactions to the epilepsy in an unselected group of patients with epilepsy under treatment in general hospitals","volume":"12","author":"Aldenkamp","year":"2003","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2010.06.014_bib26","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.yebeh.2008.02.017","article-title":"Health-related quality of life in epilepsy: findings obtained with a new Italian instrument","volume":"13","author":"Piazzini","year":"2008","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.06.014_bib27","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.yebeh.2006.09.013","article-title":"Epilepsy and women's health issues: unmet needs\u2014survey results from women with epilepsy","volume":"10","author":"Vazquez","year":"2007","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.06.014_bib28","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1212\/WNL.56.2.172","article-title":"Weight change associated with valproate and lamotrigine monotherapy in patients with epilepsy","volume":"56","author":"Biton","year":"2001","journal-title":"Neurology"}],"container-title":["Seizure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131110001433?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131110001433?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T01:39:14Z","timestamp":1761010754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1059131110001433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":28,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S1059131110001433"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2010.06.014","relation":{},"ISSN":["1059-1311"],"issn-type":[{"value":"1059-1311","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quality of life and treatment satisfaction in Spanish epilepsy patients on monotherapy with lamotrigine or valproic acid","name":"articletitle","label":"Article Title"},{"value":"Seizure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2010.06.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}