{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T03:21:25Z","timestamp":1761016885723,"version":"build-2065373602"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":964,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.seizure.2010.09.009","type":"journal-article","created":{"date-parts":[[2010,10,17]],"date-time":"2010-10-17T04:37:06Z","timestamp":1287290226000},"page":"80-82","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Sodium valproate and highly active antiretroviral therapy in HIV positive patients who develop new onset seizures"],"prefix":"10.1016","volume":"20","author":[{"given":"Yaseen","family":"Yacoob","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Iqbal","family":"Bhigjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pravikrishnen","family":"Moodley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raveen","family":"Parboosing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2010.09.009_bib0005","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0002-9343(89)80693-X","article-title":"New-onset seizures associated with human immunodeficiency virus infection: causation & clinical features in 100 cases","volume":"87","author":"Holtzman","year":"1989","journal-title":"Am J Med"},{"key":"10.1016\/j.seizure.2010.09.009_bib0010","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1001\/archneur.1990.00530060048015","article-title":"Seizures in human immunodeficiency virus infection","volume":"47","author":"Wong","year":"1990","journal-title":"Arch Neurol"},{"key":"10.1016\/j.seizure.2010.09.009_bib0015","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1001\/archneur.56.5.609","article-title":"Prospective study of new-onset seizures in patients with human immunodeficiency virus infection. Etiologic and clinical aspects","volume":"56","author":"Pascual-Sedano","year":"1999","journal-title":"Arch Neurol"},{"key":"10.1016\/j.seizure.2010.09.009_bib0020","first-page":"573","article-title":"Seizures in patients with human immunodeficiency virus infection","volume":"48","author":"Chadha","year":"2000","journal-title":"J Assoc Physicians India"},{"key":"10.1016\/j.seizure.2010.09.009_bib0025","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s11910-004-0057-x","article-title":"Special populations: the management of seizures in HIV positive patients","volume":"4","author":"Mullin","year":"2004","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"1","key":"10.1016\/j.seizure.2010.09.009_bib0030","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.seizure.2007.05.017","article-title":"Frequency of seizures and epilepsy in neurological HIV infected patients","volume":"17","author":"Kellinghaus","year":"2008","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2010.09.009_bib0035","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1212\/WNL.54.7.1404","article-title":"Therapeutic dilemma. The use of anticonvulsants in HIV-positive individuals","volume":"54","author":"Romanelli","year":"2000","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2010.09.009_bib0040","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.2174\/1381612033454676","article-title":"Concurrent use of antiretrovirals and anticonvulsants in human immunodeficiency virus (HIV) seropositive patients","volume":"9","author":"Romanelli","year":"2003","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.seizure.2010.09.009_bib0045","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/0009-2797(94)90031-0","article-title":"Valproic acid reduces the intracellular level of glutathione and stimulates human immunodeficiency virus","volume":"91","author":"Simon","year":"1994","journal-title":"Chem Biol Interact"},{"key":"10.1016\/j.seizure.2010.09.009_bib0050","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1099\/0022-1317-77-9-1993","article-title":"Sodium valproate, an anticonvulsant drug, stimulates human immunodeficiency virus type 1 replication independently of glutathione levels","volume":"77","author":"Moog","year":"1996","journal-title":"J Gen Virol"},{"key":"10.1016\/j.seizure.2010.09.009_bib0055","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1345\/aph.19014","article-title":"The use of valproic acid in HIV-positive patients","volume":"33","author":"Jennings","year":"1999","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.seizure.2010.09.009_bib0060","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/00002826-200007000-00009","article-title":"Protease inhibitors-induced carbamazepine toxicity","volume":"23","author":"Garcia","year":"2000","journal-title":"Clin Neuropharmacol"},{"key":"10.1016\/j.seizure.2010.09.009_bib0065","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1177\/070674370104600409","article-title":"The effect of divalproex sodium on viral load: a retrospective review of HIV positive patients with manic syndromes","volume":"46","author":"Maggi","year":"2001","journal-title":"Can J Psychiatry"},{"key":"10.1016\/j.seizure.2010.09.009_bib0070","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0140-6736(05)67098-5","article-title":"Depletion of latent HIV-1 infection in vivo: a proof of concept study","volume":"366","author":"Lehrman","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.seizure.2010.09.009_bib0075","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1097\/QAD.0b013e3282fd6ddc","article-title":"Prolonged valproic acid treatment does not reduce the size of latent HIV reservoir","volume":"22","author":"Sagot-Lexolle","year":"2008","journal-title":"AIDS"},{"key":"10.1016\/j.seizure.2010.09.009_bib0080","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1097\/QAD.0b013e3282fd6df4","article-title":"Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4 and Tcells","volume":"22","author":"Archin","year":"2008","journal-title":"AIDS"},{"key":"10.1016\/j.seizure.2010.09.009_bib0085","unstructured":"www.hiv-druginteractions.org. Abstracted 17 June 2009."},{"issue":"Suppl. 6","key":"10.1016\/j.seizure.2010.09.009_bib0090","first-page":"106","article-title":"Long term follow up on levetiracetam in patients with HIV infection & HAART therapy","volume":"46","author":"Locatelli","year":"2005","journal-title":"Epilepsia"}],"container-title":["Seizure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131110002104?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131110002104?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T01:40:02Z","timestamp":1761010802000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1059131110002104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S1059131110002104"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2010.09.009","relation":{},"ISSN":["1059-1311"],"issn-type":[{"type":"print","value":"1059-1311"}],"subject":[],"published":{"date-parts":[[2011,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sodium valproate and highly active antiretroviral therapy in HIV positive patients who develop new onset seizures","name":"articletitle","label":"Article Title"},{"value":"Seizure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2010.09.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}