{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:50:18Z","timestamp":1769604618777,"version":"3.49.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T00:00:00Z","timestamp":1304208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":808,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure"],"published-print":{"date-parts":[[2011,5]]},"DOI":"10.1016\/j.seizure.2010.12.010","type":"journal-article","created":{"date-parts":[[2011,1,27]],"date-time":"2011-01-27T04:35:45Z","timestamp":1296102945000},"page":"280-284","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy"],"prefix":"10.1016","volume":"20","author":[{"given":"Ren\u00e9 Andrade","family":"Machado","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arlety Garc\u00eda","family":"Espinosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daliv\u00e1n","family":"Melendrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yamila Rem\u00f3n","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor Frades","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaima Quintana","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2010.12.010_bib0005","unstructured":"Busco M. FDA advisory members agree antiepileptics pose suicidality risk, nix need for black-box warning. Medscape Medical News. http:\/\/www.medscape.com\/viewarticle\/577432; 2008."},{"issue":"5","key":"10.1016\/j.seizure.2010.12.010_bib0010","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/j.1528-1167.2009.02012.x","article-title":"The FDA alert on suicidality and antiepileptic drugs: fire or false alarm?","volume":"50","author":"Hesdorffer","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.12.010_bib0015","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.eplepsyres.2005.09.034","article-title":"FDA update","volume":"68","author":"Katz","year":"2006","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.seizure.2010.12.010_bib0020","unstructured":"Glaxo-SmithKline. Briefing document, paroxetine adult suicidality analysis: major depressive disorder and non-major depressive disorder. http:\/\/www.gsk.com\/media\/par_current_analysis.htm; 2006 [accessed 05.04.06]."},{"key":"10.1016\/j.seizure.2010.12.010_bib0025","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1001\/archpsyc.63.3.332","article-title":"Suicidality in pediatric patients treated with antidepressant drugs","volume":"63","author":"Hammad","year":"2006","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0030","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/sj.npp.1300958","article-title":"ACNP task force report on SSRIs and suicidal behavior in youth","volume":"31","author":"Mann","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.seizure.2010.12.010_bib0035","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1176\/appi.ajp.2007.07030454","article-title":"Early evidence on the effects of regulators\u2019 suicidality warnings on SSRI prescriptions and suicide in children and adolescents","volume":"164","author":"Gibbons","year":"2007","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0040","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1001\/archpsyc.64.4.466","article-title":"Impact of publicity concerning pediatric suicidality data on physician practice patterns in the United States","volume":"64","author":"Nemeroff","year":"2007","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0045","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1001\/archpsyc.63.3.246","article-title":"Suicidal risk in antidepressant drug trials","volume":"63","author":"Baldessarini","year":"2006","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0050","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1089\/cap.2007.0049","article-title":"Antidepressant prescribing practices for the treatment of children and adolescents","volume":"18","author":"Bhatia","year":"2008","journal-title":"J Child Adolsc Psychopharmacol"},{"key":"10.1016\/j.seizure.2010.12.010_bib0055","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/j.1528-1157.1997.tb01733.x","article-title":"Patients\u2019 experiences of injury as a result of epilepsy","volume":"38","author":"Buck","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.12.010_bib0060","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1111\/j.0013-9580.2004.33903.x","article-title":"Accidents inpatients with epilepsy: types, circumstances, and complications: a European cohort study","volume":"45","author":"Van den Broek","year":"2004","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.12.010_bib0065","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1136\/jnnp.2003.029223","article-title":"Reducing mortality: an important aim of epilepsy management","volume":"75","author":"Sander","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0070","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1528-1157.1989.tb05316.x","article-title":"Proposal for revised classification of epilepsies and epileptic syndromes","volume":"30","author":"Commission on Classification Terminology of the International League Against Epilepsy","year":"1989","journal-title":"Epilepsia"},{"issue":"Suppl. 20","key":"10.1016\/j.seizure.2010.12.010_bib0075","first-page":"22","article-title":"The Mini International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0080","author":"First","year":"2001"},{"key":"10.1016\/j.seizure.2010.12.010_bib0085","series-title":"Surgical treatment of the epilepsies","first-page":"245","article-title":"Neuropsychological testing for localizing and lateralizing the epileptogenic region","author":"Jones-Gotman","year":"1993"},{"key":"10.1016\/j.seizure.2010.12.010_bib0090","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/j.1528-1167.2005.49704.x","article-title":"Screening for major depression in epilepsy with common self-report depression inventories","volume":"46","author":"Jones","year":"2005","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.12.010_bib0095","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/ana.20685","article-title":"Depression and attempted suicide as risk factors for incident unprovoked seizures and epilepsy","volume":"59","author":"Hesdorffer","year":"2006","journal-title":"Ann Neurol"},{"key":"10.1016\/j.seizure.2010.12.010_bib0100","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S1474-4422(07)70175-8","article-title":"Epilepsy and risk of suicide: a population-based case\u2014control study","volume":"6","author":"Christensen","year":"2007","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.seizure.2010.12.010_bib0105","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S1525-5050(02)00008-2","article-title":"Emotional and affective disturbances in patients with epilepsy","volume":"2","author":"Beghi","year":"2002","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.12.010_bib0110","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1212\/01.WNL.0000103282.62353.85","article-title":"Depression but not seizure frequency predicts quality of life in treatment-resistant epilepsy","volume":"62","author":"Boylan","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2010.12.010_bib0115","first-page":"123","article-title":"A systematic review of the behavioral effects of levetiracetam in adults with epilepsy, cognitive disorders, or an anxiety disorder during clinical trials","volume":"4","author":"Cramer","year":"2004","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.12.010_bib0120","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1111\/j.1528-1157.1997.tb01194.x","article-title":"Cause-specific mortality in epilepsy: a cohort study of more than 9000 patients once hospitalized for epilepsy","volume":"38","author":"Nilsson","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2010.12.010_bib0125","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1159\/000054795","article-title":"Cause-specific mortality in adults with unprovoked seizures: a population-based incidence cohort study","volume":"20","author":"Rafnsson","year":"2001","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.seizure.2010.12.010_bib0130","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.yebeh.2009.09.010","article-title":"Wisconsin card sorting test performance and impulsivity in patients with temporal lobe epilepsy: suicidal risk and suicide attempts","volume":"17","author":"Arlety","year":"2010","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.12.010_bib0135","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1176\/ajp.149.8.1096","article-title":"Interictal psychiatric morbidity and focus of epilepsy in treatment-refractory patients admitted to an epilepsy unit","volume":"149","author":"Manchanda","year":"1992","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0140","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1192\/bjp.163.4.446","article-title":"Epilepsy and psychiatric disturbance","volume":"163","author":"Fiordelli","year":"1993","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0145","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/j.yebeh.2003.10.002","article-title":"Psychiatric comorbidity in patients with epilepsy: implications for diagnosis and treatment","volume":"4","author":"Devinsky","year":"2003","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.12.010_bib0150","first-page":"909","article-title":"Phenobarbital treatment and major depressive disorder in children with epilepsy","volume":"80","author":"Brent","year":"1987","journal-title":"Pediatrics"},{"key":"10.1016\/j.seizure.2010.12.010_bib0155","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0140-6736(98)10531-7","article-title":"Safety and efficacy of vigabatrin and Carbamazepine in newly diagnosed epilepsy: a multicentre randomised double-blind study. Vigabatrin European Monotherapy Study Group","volume":"354","author":"Chadwick","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.seizure.2010.12.010_bib0160","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1192\/bjp.163.4.446","article-title":"Epilepsy and psychiatric disturbance","volume":"163","author":"Crespi","year":"1993","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.seizure.2010.12.010_bib0165","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1053\/seiz.2000.0405","article-title":"Psychiatric symptoms after therapy with new antiepileptic drugs: psychopathological and seizure related variables","volume":"9","author":"Trimble","year":"2000","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2010.12.010_bib0170","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1212\/WNL.64.11.1834","volume":"64","author":"French","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2010.12.010_bib0175","first-page":"123","article-title":"A systematic review of the behavioral effects of levetiracetam in adults with epilepsy, cognitive disorders, or an anxiety disorder during clinical trials","volume":"4","author":"Cramer","year":"2004","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2010.12.010_bib0180","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.yebeh.2007.04.008","article-title":"Suicidal ideation in epilepsy and levetiracetam therapy","volume":"11","author":"Mula","year":"2007","journal-title":"Epilepsy Behav"}],"container-title":["Seizure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131110003316?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131110003316?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T01:39:34Z","timestamp":1761010774000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1059131110003316"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,5]]}},"alternative-id":["S1059131110003316"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2010.12.010","relation":{},"ISSN":["1059-1311"],"issn-type":[{"value":"1059-1311","type":"print"}],"subject":[],"published":{"date-parts":[[2011,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy","name":"articletitle","label":"Article Title"},{"value":"Seizure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2010.12.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}