{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:51:31Z","timestamp":1784130691281,"version":"3.55.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.seizure.2019.03.022","type":"journal-article","created":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T13:14:50Z","timestamp":1553778890000},"page":"31-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["Surgical resection of cavernous angioma located within eloquent brain areas: International survey of the practical management among 19 specialized centers"],"prefix":"10.1016","volume":"69","author":[{"given":"Marc","family":"Zanello","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Still","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1115-6310","authenticated-orcid":false,"given":"John R.","family":"Goodden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Colle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6684-3578","authenticated-orcid":false,"given":"Christian","family":"Schichor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Bello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Wager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Smits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8472-5313","authenticated-orcid":false,"given":"Bertil","family":"Rydenhag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Tate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Metellus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip De Witt","family":"Hamer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giannantonio","family":"Spena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Capelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0230-9282","authenticated-orcid":false,"given":"Emmanuel","family":"Mandonnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago Gil","family":"Robles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio","family":"Sarubbo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Martino Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denys","family":"Fontaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Reyns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4050-1531","authenticated-orcid":false,"given":"Sandro M.","family":"Krieg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Huberfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Wostrack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Colle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Robert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonny","family":"Noens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1792-6363","authenticated-orcid":false,"given":"Peter","family":"Muller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natan","family":"Yusupov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Conti Nibali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3659-6294","authenticated-orcid":false,"given":"Costanza","family":"Papagno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Visser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Baaijen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"Galbarritu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco","family":"Chioffi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Bucheli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9597-673X","authenticated-orcid":false,"given":"Alexandre","family":"Roux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Dezamis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6558-2342","authenticated-orcid":false,"given":"Hugues","family":"Duffau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1652-9844","authenticated-orcid":false,"given":"Johan","family":"Pallud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2019.03.022_bib0005","doi-asserted-by":"crossref","first-page":"702","DOI":"10.3171\/jns.1991.75.5.0702","article-title":"An analysis of the natural history of cavernous angiomas","volume":"75","author":"Del Curling","year":"1991","journal-title":"J Neurosurg"},{"issue":"82\u20133","key":"10.1016\/j.seizure.2019.03.022_bib0010","article-title":"[131 cases of cavernous angioma (cavernomas) of the CNS, discovered by retrospective analysis of 24,535 autopsies]","volume":"35","author":"Otten","year":"1989","journal-title":"Neurochirurgie"},{"key":"10.1016\/j.seizure.2019.03.022_bib0015","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1111\/epi.12402","article-title":"Cavernoma-related epilepsy: review and recommendations for management--report of the surgical task force of the ILAE commission on therapeutic strategies","volume":"54","author":"Rosenow","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2019.03.022_bib0020","doi-asserted-by":"crossref","first-page":"659","DOI":"10.2176\/nmc.32.659","article-title":"Indications for surgery and prognosis in patients with cerebral cavernous angiomas","volume":"32","author":"Bertalanffy","year":"1992","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.1016\/j.seizure.2019.03.022_bib0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0136619","article-title":"The role of hemosiderin excision in seizure outcome in cerebral cavernous malformation surgery: a systematic review and meta-analysis","volume":"10","author":"Ruan","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.seizure.2019.03.022_bib0030","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.neuroimage.2012.09.075","article-title":"Extended resection of hemosiderin fringe is better for seizure outcome: a study in patients with cavernous malformation associated with refractory epilepsy","volume":"61","author":"Wang","year":"2013","journal-title":"Neurol India"},{"key":"10.1016\/j.seizure.2019.03.022_bib0035","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1528-1167.2006.00468.x","article-title":"Seizure outcome after resection of cavernous malformations is better when surrounding hemosiderin-stained brain also is removed","volume":"47","author":"Baumann","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2019.03.022_bib0040","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.neuchi.2016.08.008","article-title":"Resection of cavernous angioma located in eloquent areas using functional cortical and subcortical mapping under awake conditions. Outcomes in a 50-case multicentre series","volume":"63","author":"Zanello","year":"2017","journal-title":"Neurochirurgie"},{"key":"10.1016\/j.seizure.2019.03.022_bib0045","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s00701-010-0915-z","article-title":"Cerebral cavernous malformations and intractable epilepsy: the limited usefulness of current literature","volume":"153","author":"von der Brelie","year":"2011","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.seizure.2019.03.022_bib0050","series-title":"Predictors of epileptic seizures and ability to work in supratentorial cavernous angioma located within eloquent brain areas. Rev","author":"Zanello","year":"2018"},{"key":"10.1016\/j.seizure.2019.03.022_bib0055","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.3171\/2012.9.JNS12662","article-title":"Awake mapping for resection of cavernous angioma and surrounding gliosis in the left dominant hemisphere: surgical technique and functional results: clinical article","volume":"117","author":"Matsuda","year":"2012","journal-title":"J Neurosurg"},{"key":"10.1016\/j.seizure.2019.03.022_bib0060","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/j.wneu.2014.02.004","article-title":"Intraoperative magnetic resonance imaging for resection of intra-axial brain lesions: a decade of experience using low-field magnetic resonance imaging, Polestar N-10, 20, 30 systems","volume":"82","author":"Livne","year":"2014","journal-title":"World Neurosurg"},{"key":"10.1016\/j.seizure.2019.03.022_bib0065","article-title":"Usefulness of preoperative surgical simulation with three-dimensional fusion images for resection of cerebral cavernous malformations near broca\u2019s area","volume":"2014","author":"Takahashi","year":"2014","journal-title":"Case Rep Neurol Med"},{"key":"10.1016\/j.seizure.2019.03.022_bib0070","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1097\/00006123-199805000-00054","article-title":"Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors","volume":"42","author":"Sawaya","year":"1998","journal-title":"Neurosurgery"},{"key":"10.1016\/j.seizure.2019.03.022_bib0075","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1046\/j.1528-1157.2001.4220282.x","article-title":"ILAE Commission Report. Proposal for a new classification of outcome with respect to epileptic seizures following epilepsy surgery","volume":"42","author":"Wieser","year":"2001","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2019.03.022_bib0080","series-title":"Surgical treatment of the epilepsies","year":"1993"},{"key":"10.1016\/j.seizure.2019.03.022_bib0085","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1586\/14737175.2015.1055323","article-title":"Cerebral cavernous malformations: natural history and clinical management","volume":"15","author":"Gross","year":"2015","journal-title":"Expert Rev Neurother"},{"key":"10.1016\/j.seizure.2019.03.022_bib0090","doi-asserted-by":"crossref","first-page":"E24","DOI":"10.3171\/2011.3.FOCUS1165","article-title":"The natural history of intracranial cavernous malformations","volume":"30","author":"Gross","year":"2011","journal-title":"Neurosurg Focus"},{"key":"10.1016\/j.seizure.2019.03.022_bib0095","doi-asserted-by":"crossref","DOI":"10.1093\/neuros\/nyx091","article-title":"Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel","author":"Akers","year":"2017","journal-title":"Neurosurgery"},{"key":"10.1016\/j.seizure.2019.03.022_bib0100","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1212\/WNL.0000000000000684","article-title":"Outcome after surgical or conservative management of cerebral cavernous malformations","volume":"83","author":"Moultrie","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2019.03.022_bib0105","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s00701-004-0357-6","article-title":"Successful resection of a left insular cavernous angioma using neuronavigation and intraoperative language mapping","volume":"147","author":"Duffau","year":"2005","journal-title":"Acta Neurochir (Wien)"},{"key":"10.1016\/j.seizure.2019.03.022_bib0110","first-page":"1350","article-title":"Intraoperative MRI with integrated functional neuronavigation-guided resection of supratentorial cavernous malformations in eloquent brain areas","volume":"18","author":"Sun","year":"2011","journal-title":"J Clin Neurosci Off J Neurosurg Soc Australas"},{"key":"10.1016\/j.seizure.2019.03.022_bib0115","doi-asserted-by":"crossref","first-page":"3712","DOI":"10.1200\/JCO.2008.20.5765","article-title":"Cognitive rehabilitation in patients with gliomas: a randomized, controlled trial","volume":"27","author":"Gehring","year":"2009","journal-title":"J Clin Oncol Off J Am Soc Clin Oncol"},{"key":"10.1016\/j.seizure.2019.03.022_bib0120","first-page":"106","article-title":"Developing interventions for cancer-related cognitive dysfunction in childhood Cancer survivors","author":"Castellino","year":"2014","journal-title":"JNCI J Natl Cancer Inst"},{"key":"10.1016\/j.seizure.2019.03.022_bib0125","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.seizure.2010.05.008","article-title":"Antiepileptic treatment in patients with epilepsy and other comorbidities","volume":"19","author":"Ruiz-Gim\u00e9nez","year":"2010","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2019.03.022_bib0130","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/epi.12074","article-title":"Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes","volume":"54","author":"Glauser","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2019.03.022_bib0135","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.3171\/2011.7.JNS11536","article-title":"Predictors of seizure freedom in the surgical treatment of supratentorial cavernous malformations: clinical article","volume":"115","author":"Englot","year":"2011","journal-title":"J Neurosurg"},{"key":"10.1016\/j.seizure.2019.03.022_bib0140","doi-asserted-by":"crossref","DOI":"10.1684\/epd.2016.0817","article-title":"Psychiatric and Behavioural Disorders in Children with Epilepsy (ILAE Task Force Report): adverse cognitive and behavioural effects of antiepileptic drugs in children","author":"Aldenkamp","year":"2016","journal-title":"Epileptic Disord Int Epilepsy J Videotape"},{"key":"10.1016\/j.seizure.2019.03.022_bib0145","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.eplepsyres.2014.02.018","article-title":"Beyond the lesion: the epileptogenic networks around cavernous angiomas","volume":"108","author":"Sevy","year":"2014","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.seizure.2019.03.022_bib0150","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.neuchi.2012.11.001","article-title":"A new philosophy in surgery for diffuse low-grade glioma (DLGG): oncological and functional outcomes","volume":"59","author":"Duffau","year":"2013","journal-title":"Neurochirurgie"},{"key":"10.1016\/j.seizure.2019.03.022_bib0155","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s10143-016-0797-5","article-title":"Should we resect peri-lesional hemosiderin deposits when performing lesionectomy in patients with cavernoma-related epilepsy (CRE)?","volume":"40","author":"Dammann","year":"2017","journal-title":"Neurosurg Rev"}],"container-title":["Seizure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105913111830815X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S105913111830815X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T01:52:39Z","timestamp":1761011559000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S105913111830815X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":31,"alternative-id":["S105913111830815X"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2019.03.022","relation":{},"ISSN":["1059-1311"],"issn-type":[{"value":"1059-1311","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Surgical resection of cavernous angioma located within eloquent brain areas: International survey of the practical management among 19 specialized centers","name":"articletitle","label":"Article Title"},{"value":"Seizure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2019.03.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 British Epilepsy Association. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}