{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:08:49Z","timestamp":1790359729549,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.seizure.2019.12.023","type":"journal-article","created":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T11:45:38Z","timestamp":1577965538000},"page":"22-27","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["The exploration of the spectrum of motor manifestations of anti-LGI1 encephalitis beyond FBDS"],"prefix":"10.1016","volume":"76","author":[{"given":"Xiaoyun","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiang","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liling","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yabo","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zaiying","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifeng","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youting","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2019.12.023_bib0005","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S1474-4422(10)70137-X","article-title":"Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series","volume":"9","author":"Lai","year":"2010","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0010","doi-asserted-by":"crossref","first-page":"2734","DOI":"10.1093\/brain\/awq213","article-title":"Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan\u2019s syndrome and acquired neuromyotonia","volume":"133","author":"Irani","year":"2010","journal-title":"Brain"},{"key":"10.1016\/j.seizure.2019.12.023_bib0015","doi-asserted-by":"crossref","first-page":"3799","DOI":"10.1073\/pnas.0914537107","article-title":"Disruption of LGI1\u2013linked synaptic complex causes abnormal synaptic transmission and epilepsy","volume":"107","author":"Fukata","year":"2010","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.seizure.2019.12.023_bib0020","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jneuroim.2013.10.005","article-title":"VGKC-complex\/LGI1-antibody encephalitis: clinical manifestations and response to immunotherapy","volume":"265","author":"Shin","year":"2013","journal-title":"J Neuroimmunol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1212\/WNL.0000000000003173","article-title":"Anti-LGI1 encephalitis: clinical syndrome and long-term follow-up","volume":"87","author":"van Sonderen","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2019.12.023_bib0030","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.seizure.2017.05.017","article-title":"LGI1-antibody encephalitis is characterised by frequent, multifocal clinical and subclinical seizures","volume":"50","author":"Aurangzeb","year":"2017","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2019.12.023_bib0035","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.yebeh.2017.08.011","article-title":"Seizure semiology in leucine-rich glioma-inactivated protein 1 antibody-associated limbic encephalitis","volume":"77","author":"Chen","year":"2017","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2019.12.023_bib0040","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.yebeh.2018.08.019","article-title":"Clinical and electrographic characteristics of seizures in LGI1-antibody encephalitis","volume":"88","author":"Li","year":"2018","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2019.12.023_bib0045","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1002\/epi4.12226","article-title":"Antiepileptic drug therapy in autoimmune epilepsy associated with antibodies targeting the leucine-rich glioma-inactivated protein 1","volume":"3","author":"Feyissa","year":"2018","journal-title":"Epilepsia Open"},{"key":"10.1016\/j.seizure.2019.12.023_bib0050","doi-asserted-by":"crossref","DOI":"10.1007\/s00415-019-09230-2","article-title":"Sleep disturbances are common in patients with autoimmune encephalitis","author":"Blattner","year":"2019","journal-title":"J Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0055","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1093\/brain\/awt212","article-title":"Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype","volume":"136","author":"Irani","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.seizure.2019.12.023_bib0060","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1093\/brain\/awx323","article-title":"The importance of early immunotherapy in patients with faciobrachial dystonic seizures","volume":"141","author":"Thompson","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.seizure.2019.12.023_bib0065","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S1474-4422(15)00401-9","article-title":"A clinical approach to diagnosis of autoimmune encephalitis","volume":"15","author":"Graus","year":"2016","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0070","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1002\/ana.22307","article-title":"Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis","volume":"69","author":"Dphil","year":"2011","journal-title":"Ann Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0075","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1007\/s00415-013-6946-7","article-title":"Faciobrachial dystonic seizures arise from cortico-subcortical abnormal brain areas","volume":"260","author":"Boesebeck","year":"2013","journal-title":"J Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0080","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1093\/brain\/aww012","article-title":"Motor cortex and hippocampus are the two main cortical targets in LGI1-antibody encephalitis","volume":"139","author":"Navarro","year":"2016","journal-title":"Brain"},{"key":"10.1016\/j.seizure.2019.12.023_bib0085","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1212\/WNL.0b013e3182152808","article-title":"Tonic seizures: a diagnostic clue of anti-LGI1 encephalitis?","volume":"76","author":"Striano","year":"2011","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2019.12.023_bib0090","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.clinph.2017.10.014","article-title":"Frontal infraslow activity marks the motor spasms of anti-LGI1 encephalitis","volume":"129","author":"Wennberg","year":"2018","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0095","doi-asserted-by":"crossref","first-page":"e155","DOI":"10.1111\/epi.13436","article-title":"Subclinical temporal EEG seizure pattern in LGI1\u2010antibody\u2013mediated encephalitis","volume":"57","author":"Steriade","year":"2016","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2019.12.023_bib0100","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.yebeh.2015.12.041","article-title":"Clinical characterization of autoimmune LGI1 antibody limbic encephalitis","volume":"56","author":"Gao","year":"2016","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2019.12.023_bib0105","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1212\/WNL.0b013e31825f0522","article-title":"Vincent. A. Immunotherapy-responsive chorea as the presenting feature of LGI1-antibody encephalitis","volume":"79","author":"Tofaris","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2019.12.023_bib0110","doi-asserted-by":"crossref","first-page":"e385","DOI":"10.1212\/NXI.0000000000000385","article-title":"IgLON5 antibody: neurological accompaniments and outcomes in 20 patients","volume":"4","author":"Honorat","year":"2017","journal-title":"Neurol Neuroimmunol Neuroinflammation"},{"key":"10.1016\/j.seizure.2019.12.023_bib0115","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/brain\/awx189","article-title":"Movement disorders with neuronal antibodies: syndromic approach, genetic parallels and pathophysiology","volume":"141","author":"Balint","year":"2018","journal-title":"Brain"},{"key":"10.1016\/j.seizure.2019.12.023_bib0120","article-title":"Expanded phenotypes and outcomes among 256 LGI1\/CASPR2-IgG positive patients","author":"Gadoth","year":"2019","journal-title":"Ann Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0125","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1053\/smrv.2001.0166","article-title":"Agrypnia excitata: clinical features and pathophysiological implications","volume":"5","author":"Lugaresi","year":"2001","journal-title":"Sleep Med Rev"},{"issue":"Suppl 2","key":"10.1016\/j.seizure.2019.12.023_bib0130","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.sleep.2011.10.004","article-title":"Agrypnia excitata","volume":"12","author":"Lugaresi","year":"2011","journal-title":"Sleep Med"},{"key":"10.1016\/j.seizure.2019.12.023_bib0135","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s11910-013-0341-8","article-title":"Agrypnia excitata","volume":"13","author":"Provini","year":"2013","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.seizure.2019.12.023_bib0140","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0168-0102(02)00027-5","article-title":"Functional significance of the cortico-subthalamo-pallidal \u2018hyperdirect\u2019 pathway","volume":"42","author":"Nambu","year":"2002","journal-title":"Neurosci Res"},{"key":"10.1016\/j.seizure.2019.12.023_bib0145","doi-asserted-by":"crossref","first-page":"275","DOI":"10.2183\/pjab.94.019","article-title":"Functions and dysfunctions of the basal ganglia in humans","volume":"94","author":"Yanagisawa","year":"2018","journal-title":"Proc Jpn Acad, Ser B, Phys Biol Sci"},{"key":"10.1016\/j.seizure.2019.12.023_bib0150","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1001\/archneurol.2010.317","article-title":"Kinesigenic dyskinesia in a case of voltage-gated potassium channel-complex protein antibody encephalitis","volume":"68","author":"Aradillas","year":"2011","journal-title":"Arch Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0155","doi-asserted-by":"crossref","first-page":"e161","DOI":"10.1212\/NXI.0000000000000161","article-title":"Basal ganglia T1 hyperintensity in LGI1-autoantibody faciobrachial dystonic seizures","volume":"2","author":"Flanagan","year":"2015","journal-title":"Neurol Neuroimmunol Neuroinflamm"},{"key":"10.1016\/j.seizure.2019.12.023_bib0160","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/nrneurol.2017.43","article-title":"The value of LGI1, Caspr2 and voltage-gated potassium channel antibodies in encephalitis","volume":"13","author":"van Sonderen","year":"2017","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0165","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1212\/01.wnl.0000312275.04260.a0","article-title":"Clinical spectrum of voltage-gated potassium channel autoimmunity","volume":"70","author":"Tan","year":"2008","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2019.12.023_bib0170","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1001\/archneurol.2011.106","article-title":"Sleep manifestations of voltage-gated potassium channel complex autoimmunity","volume":"68","author":"Cornelius","year":"2011","journal-title":"Arch Neurol"},{"key":"10.1016\/j.seizure.2019.12.023_bib0175","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.smrv.2015.07.003","article-title":"From state dissociation to status dissociatus","volume":"28","author":"Antelmi","year":"2016","journal-title":"Sleep Med Rev"}],"container-title":["Seizure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131119305734?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131119305734?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T01:53:46Z","timestamp":1761011626000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1059131119305734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":35,"alternative-id":["S1059131119305734"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2019.12.023","relation":{},"ISSN":["1059-1311"],"issn-type":[{"value":"1059-1311","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The exploration of the spectrum of motor manifestations of anti-LGI1 encephalitis beyond FBDS","name":"articletitle","label":"Article Title"},{"value":"Seizure","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2019.12.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 British Epilepsy Association. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}