{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:59:19Z","timestamp":1781139559146,"version":"3.54.1"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Ministero della Salute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seizure-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seizure: European Journal of Epilepsy"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.seizure.2026.05.021","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T19:36:17Z","timestamp":1779305777000},"page":"203-210","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Epilepsia partialis continua beyond status epilepticus: a generator-based neurophysiological framework for clinical decision-making"],"prefix":"10.1016","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9573-102X","authenticated-orcid":false,"given":"Lucia","family":"Fusco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.seizure.2026.05.021_bib0001","first-page":"47","article-title":"Eine besondere form von cortikaler epilepsie","volume":"14","author":"Kozhevnikov","year":"1895","journal-title":"Neurologisches Centralblatt"},{"key":"10.1016\/j.seizure.2026.05.021_bib0002","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/brain\/119.2.393","article-title":"Clinical and physiological features of epilepsia partialis continua","volume":"119","author":"Cockerell","year":"1996","journal-title":"Brain"},{"issue":"6","key":"10.1016\/j.seizure.2026.05.021_bib0003","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1111\/j.1528-1167.2010.02974.x","article-title":"Clinical course and variability of non-rasmussen, nonstroke motor and sensory epilepsia partialis continua: a European survey and analysis of 65 cases","volume":"52","author":"Mameniskiene","year":"2011","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2026.05.021_bib0004","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.seizure.2016.10.010","article-title":"Epilepsia partialis continua: a review","volume":"44","author":"Mameniskiene","year":"2017","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2026.05.021_bib0005","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1111\/epi.16650","article-title":"Diagnostic algorithm for children presenting with epilepsia partialis continua","volume":"61","author":"Surana","year":"2020","journal-title":"Epilepsia"},{"issue":"10","key":"10.1016\/j.seizure.2026.05.021_bib0006","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1111\/epi.13121","article-title":"A definition and classification of status epilepticus \u2013 report of the ILAE task force on classification of status epilepticus","volume":"56","author":"Trinka","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2026.05.021_bib0007","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/mus.20234","article-title":"Electrophysiological studies of myoclonus","volume":"31","author":"Shibasaki","year":"2005","journal-title":"Muscle Nerve"},{"issue":"12","key":"10.1016\/j.seizure.2026.05.021_bib0008","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1002\/mds.29990","article-title":"Substantiating the short burst duration in cortical myoclonus","volume":"39","author":"van der Veen","year":"2024","journal-title":"Movement Disorder"},{"key":"10.1016\/j.seizure.2026.05.021_bib0009","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1093\/brain\/awaa129","article-title":"Unravelling the enigma of cortical tremor and other forms of cortical myoclonus","volume":"143","author":"Latorre","year":"2020","journal-title":"Brain"},{"key":"10.1016\/j.seizure.2026.05.021_bib0010","series-title":"Epilepsy and the functional anatomy of the human brain","author":"Penfield","year":"1954"},{"key":"10.1016\/j.seizure.2026.05.021_bib0011","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1007\/s00259-014-2900-x","article-title":"Delineation of seizure onset zone using ictal PET in epilepsia partialis continua","volume":"41","author":"Van den Broeck","year":"2014","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.seizure.2026.05.021_bib0012","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.eplepsyres.2012.09.003","article-title":"Etiology, clinical features and outcome of epilepsia partialis continua in cohort of 51 children","volume":"104","author":"Kravljanac","year":"2013","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.seizure.2026.05.021_bib0013","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/j.braindev.2017.01.011","article-title":"Electro-clinical-etiological associations of epilepsia partialis continua in 57 chinese children","volume":"39","author":"Li","year":"2017","journal-title":"Brain Dev"},{"issue":"Suppl.1","key":"10.1016\/j.seizure.2026.05.021_bib0014","first-page":"S29","article-title":"Focale status epilepticus and epilepsia partialis continua in adults and children","volume":"34","author":"Shomer","year":"1993","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2026.05.021_bib0015","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.clineuro.2018.06.004","article-title":"Epilepsia partialis continua: correlation of semeiology, outcome, and electrophysiologic features","volume":"171","author":"Atmaca","year":"2018","journal-title":"Clin Neurol Neurosurg"},{"key":"10.1016\/j.seizure.2026.05.021_bib0016","first-page":"65","article-title":"Ictal haemodynamic changes in a patient affectd by \u201csubtle","volume":"21","author":"Vaudano","year":"2012","journal-title":"Epilepsia Partialis Continua Seizure."},{"key":"10.1016\/j.seizure.2026.05.021_bib0017","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.clinph.2019.01.005","article-title":"Cortical inhibitory dysfunction in epilepsia partialis continua: a high frequency oscillation somatosensory evoked potentials study","volume":"130","author":"Insola","year":"2019","journal-title":"Clin Neurophysiol"},{"issue":"8","key":"10.1016\/j.seizure.2026.05.021_bib0018","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0272902","article-title":"Critical dynamics in the spread of focal epileptic seizures: network connectivity, neural excitability and phase transition","volume":"17","author":"Moosavi","year":"2022","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.seizure.2026.05.021_bib0019","doi-asserted-by":"crossref","DOI":"10.1111\/epi.13067","article-title":"Epilepsia partialis continua responsive to neocortical electrical stimulaton","volume":"56","author":"Valentin","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2026.05.021_bib0020","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1053\/seiz.2001.0646","article-title":"Epilepsia partialis continua \u2013 a clinical and electroencephalographic study","volume":"11","author":"Pandian","year":"2002","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2026.05.021_bib0021","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.yebeh.2004.10.010","article-title":"A patient with a 44-year history of epilepsia partialis continua caused by a perirolandic cortical dysplasia","volume":"6","author":"Nakken","year":"2005","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2026.05.021_bib0022","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1093\/brain\/awf176","article-title":"The natural history of Rasmussen\u2019s encephalitis","volume":"125","author":"Bien","year":"2002","journal-title":"Brain."},{"key":"10.1016\/j.seizure.2026.05.021_bib0023","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1212\/WNL.60.3.422","article-title":"Rasmussen\u2019s encephalitis. Early characteristics allow diagnosis","volume":"60","author":"Granata","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.seizure.2026.05.021_bib0024","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.yebeh.2015.05.003","article-title":"Pathophysiology of mitochondrial disease causing epilepsy and status epilepticus","volume":"49","author":"Rahman","year":"2015","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.seizure.2026.05.021_bib0025","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/ane.13130","article-title":"Epileptic phenotypes in children with early-onset mitochondrial diseases","volume":"140","author":"Matricardi","year":"2019","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.seizure.2026.05.021_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmg.2018.11.025","article-title":"Progressive myoclonus epilepsy and ceroidolipofuscinosis 14: the multifaceted phenotypic spectrum of KCTD7-related disorders","volume":"62","author":"Mastrangelo","year":"2019","journal-title":"Eur J Med Genet"},{"issue":"2","key":"10.1016\/j.seizure.2026.05.021_bib0027","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1684\/epd.2021.1262","article-title":"Successful treatment of epilepsia partialis continua with perampanel: two pediatric cases","volume":"23","author":"Mir","year":"2021","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.seizure.2026.05.021_bib0028","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.seizure.2017.03.003","article-title":"Alternating hemiplegia and epilepsia partialis continua: a new phenotype for a novel compound TBC1D24 mutation","volume":"47","author":"Ragona","year":"2017","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2026.05.021_bib0029","doi-asserted-by":"crossref","first-page":"750","DOI":"10.3389\/fneur.2017.00750","article-title":"Homozygous TBC1D24 mutation in a case of epilepsia partialis continua","volume":"8","author":"Zhou","year":"2018","journal-title":"Front Neurol"},{"key":"10.1016\/j.seizure.2026.05.021_bib0030","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00381-018-3749-2","article-title":"Bottom-of-sulcus focal cortical dysplasia presenting as epilepsia partialis continua multimodality characterization including 7T MRI","volume":"34","author":"Kelley","year":"2018","journal-title":"Child Nerv Syst"},{"issue":"6","key":"10.1016\/j.seizure.2026.05.021_bib0031","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1136\/jnnp.54.6.556","article-title":"Reversible operculum syndrome caused by progressive epilepsia partialis continua in a child with left hemimegalencephaly","volume":"54","author":"Fusco","year":"1991","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.seizure.2026.05.021_bib0032","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/epi.17807","article-title":"Hemispheric epilepsy surgery for hemimegalencephaly: the UCLA experience","volume":"65","author":"Goel","year":"2024","journal-title":"Epilepsia"},{"issue":"7","key":"10.1016\/j.seizure.2026.05.021_bib0033","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1111\/j.1528-1167.2009.02504.x","article-title":"Epileptic phenotypes in children with respiratory chain disorders","volume":"51","author":"El Sabbagh","year":"2010","journal-title":"Epilepsia"},{"key":"10.1016\/j.seizure.2026.05.021_bib0034","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1007\/s12031-022-01993-0","article-title":"Epilepsia partialis continua: a clinical feature of a missense variant in the ACDK3 gene and poor response to therapy","volume":"72","author":"Ashrafi","year":"2022","journal-title":"J Mol Neurosci"},{"key":"10.1016\/j.seizure.2026.05.021_bib0035","first-page":"57","article-title":"Hemispherotomy in Rasmussen encephalitis: long-term outcome in an Italian series of 16 patients","volume":"65","author":"Granata","year":"2024","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.seizure.2026.05.021_bib0036","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/epd2.20033","article-title":"Epilepisa partialis continua and unilateral cortical-subcortical FLAIR-hyperintense lesion in Rasmussen\u2019s encephalitis: it is diagnostic?","volume":"25","author":"Jagtap","year":"2023","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.seizure.2026.05.021_bib0037","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1007\/s12031-022-01993-0","article-title":"Epilepsia partialis continua a clinical feature of a missense variant in the ADCK3gene and poor response to therapy","volume":"72","author":"Ashrafi","year":"2022","journal-title":"J Mol Neurosc"},{"issue":"1","key":"10.1016\/j.seizure.2026.05.021_bib0038","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1684\/epd.2021.1375","article-title":"Epilepsia partialis continua associated with the p.Arg403Cys variant of the DNM1L gene: an unusual clinical progression with two episodes of super.Refractory status epilepticus with a 13-year remission interval","volume":"24","author":"Minghetti","year":"2022","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.seizure.2026.05.021_bib0039","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.seizure.2025.01.005","article-title":"Management of epilepsia partialis continua: a systematic review","volume":"125","author":"Tan","year":"2025","journal-title":"Seizure"},{"issue":"1","key":"10.1016\/j.seizure.2026.05.021_bib0040","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1002\/mds.22185","article-title":"Botulinum toxin treatment of epilepsia partialis continua","volume":"24","author":"Kang","year":"2009","journal-title":"Mov Disord"},{"key":"10.1016\/j.seizure.2026.05.021_bib0041","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.seizure.2024.10.018","article-title":"Neuromodulation with transcranial magnetic stimulation in epilepsia partialis continua: scoping review and clinical experience","volume":"123","author":"Velasco-Merida","year":"2024","journal-title":"Seizure"},{"key":"10.1016\/j.seizure.2026.05.021_bib0042","article-title":"Successful treatment of super-refractory focal status epilepticus: surgery, vagus nerve stimulation and botox for epilepsia partialis continua","volume":"31","author":"Zalmay","year":"2025","journal-title":"Epilepsy Behav Rep"}],"container-title":["Seizure: European Journal of Epilepsy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131126001512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1059131126001512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:11:05Z","timestamp":1781136665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1059131126001512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":42,"alternative-id":["S1059131126001512"],"URL":"https:\/\/doi.org\/10.1016\/j.seizure.2026.05.021","relation":{},"ISSN":["1059-1311"],"issn-type":[{"value":"1059-1311","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epilepsia partialis continua beyond status epilepticus: a generator-based neurophysiological framework for clinical decision-making","name":"articletitle","label":"Article Title"},{"value":"Seizure: European Journal of Epilepsy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.seizure.2026.05.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 British Epilepsy Association. Published by Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}