{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:14:10Z","timestamp":1788891250869,"version":"build-2803163510"},"reference-count":15,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","semarthritisrheumatism.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Arthritis and Rheumatism"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.semarthrit.2015.05.007","type":"journal-article","created":{"date-parts":[[2015,5,21]],"date-time":"2015-05-21T07:47:23Z","timestamp":1432194443000},"page":"357-360","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Granulomatous disease associated with NOD2 sequence variants and familial camptodactyly: An intermediate form of NOD2-associated diseases?"],"prefix":"10.1016","volume":"45","author":[{"given":"Min","family":"Shen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocio","family":"Moran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Tomecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingping","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semarthrit.2015.05.007_bib1","doi-asserted-by":"crossref","first-page":"4812","DOI":"10.1074\/jbc.M008072200","article-title":"Nod2, a Nod1\/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB","volume":"276","author":"Ogura","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib2","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1136\/gut.49.6.752","article-title":"NOD2 (CARD15), the first susceptibility gene for Crohn\u05f3s disease","volume":"49","author":"McGovern","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib3","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.semarthrit.2012.12.005","article-title":"Nucleotide-binding oligomerization domain containing 2: structure, function, and diseases","volume":"43","author":"Yao","year":"2013","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib4","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.1002\/art.22122","article-title":"Pediatric granulomatous arthritis: an international registry","volume":"54","author":"Ros\u00e9","year":"2006","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib5","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1546-0096-12-33","article-title":"Blau syndrome, the prototypic auto-inflammatory granulomatous disease","volume":"12","author":"Wouters","year":"2014","journal-title":"Pediatr Rheumatol Oline J"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib6","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.autrev.2012.07.028","article-title":"Blau syndrome, clinical and genetic aspects","volume":"12","author":"Sfriso","year":"2012","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib7","doi-asserted-by":"crossref","DOI":"10.1093\/rheumatology\/kev207","article-title":"NOD2-associated autoinflammatory disease: a large cohort study","author":"Yao","year":"2015","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib8","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1073\/pnas.0530276100","article-title":"Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases","volume":"100","author":"Chamaillard","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib9","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.clim.2009.05.005","article-title":"NOD2-associated diseases: bridging innate immunity and autoinflammation","volume":"134","author":"Borzutzky","year":"2010","journal-title":"Clin Immunol"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib10","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1086\/367848","article-title":"A novel NOD2\/CARD15 haplotype conferring risk for Crohn disease in Ashkenazi Jews","volume":"72","author":"Sugimura","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib11","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1053\/j.gastro.2003.12.026","article-title":"Failure to replicate the association of the novel NOD2\/CARD15 haplotype (S268P-JW1) to Crohn\u05f3s disease in the Jewish Israeli population","volume":"126","author":"Karban","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib12","doi-asserted-by":"crossref","first-page":"R148","DOI":"10.1186\/ar3462","article-title":"A new category of autoinflammatory disease associated with NOD2 gene mutation","volume":"13","author":"Yao","year":"2011","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib13","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1164\/ajrccm.186.5.465","article-title":"Granulomatous pneumonitis associated with adult-onset Blau-like syndrome","volume":"186","author":"Yao","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib14","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/35079107","article-title":"Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn\u05f3s disease","volume":"411","author":"Hugot","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.semarthrit.2015.05.007_bib15","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1399-0039.2010.01628.x","article-title":"Caspase recruitment domain 15 gene haplotypes in sarcoidosis","volume":"77","author":"Pabst","year":"2011","journal-title":"Tissue Antigens"}],"container-title":["Seminars in Arthritis and Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017215001134?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017215001134?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T08:50:37Z","timestamp":1537606237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049017215001134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S0049017215001134"],"URL":"https:\/\/doi.org\/10.1016\/j.semarthrit.2015.05.007","relation":{},"ISSN":["0049-0172"],"issn-type":[{"value":"0049-0172","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Granulomatous disease associated with NOD2 sequence variants and familial camptodactyly: An intermediate form of NOD2-associated diseases?","name":"articletitle","label":"Article Title"},{"value":"Seminars in Arthritis and Rheumatism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semarthrit.2015.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}