{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:33:05Z","timestamp":1792801985669,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","semarthritisrheumatism.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Arthritis and Rheumatism"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.semarthrit.2016.02.005","type":"journal-article","created":{"date-parts":[[2016,2,27]],"date-time":"2016-02-27T12:35:06Z","timestamp":1456576506000},"page":"115-123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":114,"title":["Impaired quality of life in systemic sclerosis and patient perception of the disease: A large international survey"],"prefix":"10.1016","volume":"46","author":[{"given":"Camelia","family":"Frantz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Avouac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Distler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fazia","family":"Amrouche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Godard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann Tyrrell","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Varga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Matucci-Cerinic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yannick","family":"Allanore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semarthrit.2016.02.005_bib1","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1056\/NEJMra0806188","article-title":"Scleroderma","volume":"360","author":"Gabrielli","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib2","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1002\/art.38098","article-title":"2013 Classification criteria for systemic sclerosis: an American College of Rheumatology\/European League against Rheumatism collaborative initiative","volume":"65","author":"Van den Hoogen","year":"2013","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib3","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1093\/rheumatology\/ker269","article-title":"Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies","volume":"51","author":"Elhai","year":"2012","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib4","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.semarthrit.2014.05.010","article-title":"Mortality and survival in systemic sclerosis: systematic review and meta-analysis","volume":"44","author":"Rubio-Rivas","year":"2014","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib5","doi-asserted-by":"crossref","first-page":"768","DOI":"10.3899\/jrheum.080281","article-title":"Quality of life in patients with systemic sclerosis compared to the general population and patients with other chronic conditions","volume":"36","author":"Hudson","year":"2009","journal-title":"J Rheumatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib6","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.3899\/jrheum.081057","article-title":"Clinical correlates of self-reported physical health status in systemic sclerosis","volume":"36","author":"Hudson","year":"2009","journal-title":"J Rheumatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib7","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1002\/art.1780401110","article-title":"The value of the Health Assessment Questionnaire and special patient-generated scales to demonstrate change in systemic sclerosis patients over time","volume":"40","author":"Steen","year":"1997","journal-title":"Arthritis Rheum"},{"issue":"2 Suppl 76","key":"10.1016\/j.semarthrit.2016.02.005_bib8","first-page":"S71","article-title":"Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry.","volume":"31","author":"Guillevin","year":"2013","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib9","doi-asserted-by":"crossref","first-page":"992","DOI":"10.3899\/jrheum.110826","article-title":"Effect of gastrointestinal manifestations on quality of life in 87 consecutive patients with systemic sclerosis","volume":"39","author":"Omair","year":"2012","journal-title":"J Rheumatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib10","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1097\/MEG.0b013e32831dac75","article-title":"Lower gastrointestinal symptoms and quality of life in patients with systemic sclerosis: a population-based study","volume":"21","author":"Franck-Larsson","year":"2009","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib11","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1093\/rheumatology\/kel189","article-title":"Impact of pain in health related quality of life of patients with systemic sclerosis","volume":"45","author":"Georges","year":"2006","journal-title":"Rheumatology"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib12","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1136\/ard.2007.075721","article-title":"The relationship of dyspnoea to function and quality of life in systemic sclerosis","volume":"67","author":"Baron","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib13","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/acr.20676","article-title":"Work productivity in scleroderma: analysis from the University of California, Los Angeles scleroderma quality of life study","volume":"64","author":"Singh","year":"2012","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib14","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/acr.22167","article-title":"Social economic costs and health-related quality of life in patients with systemic sclerosis in Spain","volume":"66","author":"L\u00f3pez-Bastida","year":"2014","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib15","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1093\/rheumatology\/ker523","article-title":"Work status and its determinants among patients with systemic sclerosis: a systematic review","volume":"51","author":"Schouffoer","year":"2012","journal-title":"Rheumatol Oxf Engl"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib16","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.semarthrit.2011.01.002","article-title":"Determinants of work disability in patients with systemic sclerosis: a longitudinal study of the GENISOS cohort","volume":"41","author":"Sharif","year":"2011","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib17","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1136\/annrheumdis-2011-200742","article-title":"Update on the profile of the EUSTAR cohort: an analysis of the EULAR Scleroderma Trials and Research group database","volume":"71","author":"Meier","year":"2012","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib18","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1002\/art.24676","article-title":"Health-related quality of life in systemic sclerosis: a systematic review","volume":"61","author":"Hudson","year":"2009","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib19","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"Von Elm","year":"2007","journal-title":"Lancet Lond Engl"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib20","series-title":"SF-36 health survey: manual and interpretation guide","author":"Ware","year":"2000"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib21","unstructured":"Ware JE, Kosinski M, Turner-Bowker DM, Gandek B. User\u2019s manual for the SF-12v2 Health Survey. Linc RI Qual Inc [Internet], Available from: \u3008http:\/\/opencourses.emu.edu.tr\/pluginfile.php\/8472\/mod_resource\/content\/1\/SF-12v2%20Manual.pdf\u3009; 2002 [cited August 23, 2015]."},{"key":"10.1016\/j.semarthrit.2016.02.005_bib22","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","article-title":"The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection","volume":"30","author":"Ware","year":"1992","journal-title":"Med Care"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/08870440290001494","article-title":"The revised illness perception questionnaire (IPQ-R)","volume":"17","author":"Moss-Morris","year":"2002","journal-title":"Psychol Health."},{"key":"10.1016\/j.semarthrit.2016.02.005_bib24","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/1477-7525-7-19","article-title":"Additional impact of concomitant hypertension and osteoarthritis on quality of life among patients with type 2 diabetes in primary care in Germany\u2014a cross-sectional survey","volume":"7","author":"Miksch","year":"2009","journal-title":"Health Qual Life Outcomes"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib25","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.jpsychores.2012.12.008","article-title":"Predicting self-care behaviours of patients with type 2 diabetes: the importance of beliefs about behaviour, not just beliefs about illness","volume":"74","author":"French","year":"2013","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib26","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/ndt\/gfn449","article-title":"Symptom clusters in incident dialysis patients: associations with clinical variables and quality of life","volume":"24","author":"Thong","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib27","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jpsychores.2009.08.010","article-title":"Illness representations are associated with fluid nonadherence among hemodialysis patients","volume":"68","author":"Chilcot","year":"2010","journal-title":"J Psychosom Res"},{"issue":"4","key":"10.1016\/j.semarthrit.2016.02.005_bib28","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s00392-012-0531-4","article-title":"Generic and disease-specific health-related quality of life in patients with chronic systolic heart failure: impact of depression","volume":"102","author":"Schowalter","year":"2013","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib29","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1002\/art.24674","article-title":"Illness perceptions in patients with osteoarthritis: change over time and association with disability","volume":"61","author":"Bijsterbosch","year":"2009","journal-title":"Arthritis Care Res"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib30","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1136\/annrheumdis-2014-206386","article-title":"A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study","volume":"75","author":"Elhai","year":"2016","journal-title":"Ann Rheum Dis"},{"issue":"6 Suppl 86","key":"10.1016\/j.semarthrit.2016.02.005_bib31","first-page":"S88","article-title":"Frequency and impact of disease symptoms experienced by patients with systemic sclerosis from five European countries","volume":"32","author":"Willems","year":"2014","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib32","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1093\/rheumatology\/kev002","article-title":"Prediction and impact of attacks of Raynaud\u2019s phenomenon, as judged by patient perception","volume":"54","author":"Hughes","year":"2015","journal-title":"Rheumatol Oxf Engl"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib33","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s10067-014-2525-2","article-title":"Functioning and health-related quality of life in Chinese patients with systemic sclerosis: a case-control study","volume":"33","author":"Chan","year":"2014","journal-title":"Clin Rheumatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib34","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1002\/art.22580","article-title":"Impact of oral cyclophosphamide on health-related quality of life in patients with active scleroderma lung disease: results from the scleroderma lung study","volume":"56","author":"Khanna","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib35","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3899\/jrheum.090677","article-title":"Anti-RNA polymerase III antibody prevalence and associated clinical manifestations in a large series of French patients with systemic sclerosis: a cross-sectional study","volume":"37","author":"Meyer","year":"2010","journal-title":"J Rheumatol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib36","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/art.38219","article-title":"Prevalence of anti-RNA polymerase III antibodies in systemic sclerosis: new data from a French cohort and a systematic review and meta-analysis","volume":"66","author":"Sobanski","year":"2014","journal-title":"Arthritis Rheumatol"},{"issue":"5","key":"10.1016\/j.semarthrit.2016.02.005_bib37","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1080\/14768320500094177","article-title":"The impact of illness representations and disease activity on adjustment in women with rheumatoid arthritis: a longitudinal study","volume":"20","author":"Dr","year":"2005","journal-title":"Psychol Health"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib38","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1348\/014466502163949","article-title":"Psychological stress, distress and disability in patients with psoriasis: consensus and variation in the contribution of illness perceptions, coping and alexithymia","volume":"41","author":"Fortune","year":"2002","journal-title":"Br J Clin Psychol"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib39","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/msc.223","article-title":"The association of illness perceptions with physical and mental health in systemic sclerosis patients: an exploratory study","volume":"10","author":"Arat","year":"2012","journal-title":"Musculoskeletal Care"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib40","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/art.11385","article-title":"Systemic sclerosis: patients\u2019 perceptions of their condition","volume":"49","author":"Richards","year":"2003","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib41","doi-asserted-by":"crossref","first-page":"3573","DOI":"10.1007\/s00296-011-2230-2","article-title":"Living with scleroderma: patients\u2019 perspectives, a phenomenological study","volume":"32","author":"Cinar","year":"2012","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib42","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1111\/jocn.12283","article-title":"Coping strategies for activities of daily living in women whose hands affected by systemic sclerosis","volume":"23","author":"Cinar","year":"2014","journal-title":"J Clin Nurs"},{"issue":"4","key":"10.1016\/j.semarthrit.2016.02.005_bib43","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1007\/s00296-012-2481-6","article-title":"Does cigarette smoking mitigate the severity of skin disease in systemic sclerosis?","volume":"33","author":"Gyger","year":"2013","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib44","doi-asserted-by":"crossref","first-page":"3098","DOI":"10.1002\/art.30492","article-title":"Cigarette smoking is not a risk factor for systemic sclerosis","volume":"63","author":"Chaudhary","year":"2011","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2016.02.005_bib45","doi-asserted-by":"crossref","first-page":"g1151","DOI":"10.1136\/bmj.g1151","article-title":"Change in mental health after smoking cessation: systematic review and meta-analysis","volume":"348","author":"Taylor","year":"2014","journal-title":"Br Med J"}],"container-title":["Seminars in Arthritis and Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017216000615?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017216000615?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T20:55:01Z","timestamp":1536958501000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049017216000615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S0049017216000615"],"URL":"https:\/\/doi.org\/10.1016\/j.semarthrit.2016.02.005","relation":{},"ISSN":["0049-0172"],"issn-type":[{"value":"0049-0172","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impaired quality of life in systemic sclerosis and patient perception of the disease: A large international survey","name":"articletitle","label":"Article Title"},{"value":"Seminars in Arthritis and Rheumatism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semarthrit.2016.02.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}