{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T18:33:07Z","timestamp":1777055587113,"version":"3.51.4"},"reference-count":21,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"European Union 7th Framework","award":["316265"],"award-info":[{"award-number":["316265"]}]},{"name":"European Union 7th Framework","award":["FP7\/REGPOT-2012-2013.1"],"award-info":[{"award-number":["FP7\/REGPOT-2012-2013.1"]}]},{"name":"European Union 7th Framework","award":["PI11\/02857"],"award-info":[{"award-number":["PI11\/02857"]}]},{"DOI":"10.13039\/501100008530","name":"FEDER","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Arthritis and Rheumatism"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.semarthrit.2018.09.005","type":"journal-article","created":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T13:40:24Z","timestamp":1538055624000},"page":"1025-1029","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Relationship between damage and mortality in juvenile-onset systemic lupus erythematosus: Cluster analyses in a large cohort from the Spanish Society of Rheumatology Lupus Registry (RELESSER)"],"prefix":"10.1016","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6597-3565","authenticated-orcid":false,"given":"V.","family":"Torrente-Segarra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.C.","family":"Salman Monte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"R\u00faa-Figueroa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"De U\u00f1a-\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8859-9465","authenticated-orcid":false,"given":"V.","family":"Balboa-Barreiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.J.","family":"L\u00f3pez-Longo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7264-2577","authenticated-orcid":false,"given":"M.","family":"Galindo-Izquierdo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Calvo-Al\u00e9n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Oliv\u00e9-Marqu\u00e9s","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Mouri\u00f1o-Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Horcada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2178-5930","authenticated-orcid":false,"given":"A.","family":"S\u00e1nchez-Atrio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Montilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Salgado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"D\u00edez-\u00c1lvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Blanco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6002-1239","authenticated-orcid":false,"given":"J.L.","family":"Andreu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Fern\u00e1ndez-Berrizbeitia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.A.","family":"Hern\u00e1ndez-Beriain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gantes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Hern\u00e1ndez-Cruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Pecond\u00f3n-Espa\u00f1ol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Marras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Bonilla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Pego-Reigosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.semarthrit.2018.09.005_bib0001","first-page":"490","article-title":"Outcome measures to be used in clinical trials in systemic lupus erythematosus","volume":"26","author":"Strand","year":"1999","journal-title":"J Rheumatol"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0002","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1177\/0961203307087612","article-title":"Lupus: improving long-term prognosis","volume":"17","author":"Doria","year":"2008","journal-title":"Lupus"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0003","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/j.semarthrit.2011.11.002","article-title":"Global trend of survival and damage of systemic lupus erythematosus: meta-analysis and meta-regression of observational studies from the 1950s to 2000s","volume":"41","author":"Mak","year":"2012","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0004","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/art.1780390303","article-title":"The development and initial validation of the Systemic Lupus International Collaborating Clinics\/American College of Rheumatology damage index for systemic lupus erythematosus","volume":"39","author":"Gladman","year":"1996","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0005","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/art.1780400506","article-title":"The reliability of the Systemic Lupus International Collaborating Clinics\/American College of Rheumatology damage index in patients with systemic lupus erythematosus","volume":"40","author":"Gladman","year":"1997","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0006","first-page":"373","article-title":"The Systemic Lupus International Collaborating Clinics\/American College of Rheumatology (SLICC\/ACR) damage index for Systemic lupus erythematosus international comparison","volume":"27","author":"Gladman","year":"2000","journal-title":"J Rheumatol"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0007","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/nrrheum.2012.208","article-title":"Global trends, potential mechanisms and early detection of organ damage in SLE","volume":"9","author":"Mak","year":"2013","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0008","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.semarthrit.2013.05.003","article-title":"The Systemic Lupus International Collaborating Clinics (SLICC) damage index: a systematic literature review","volume":"43","author":"Sutton","year":"2013","journal-title":"Semin Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0009","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1191\/096120301670679959","article-title":"Early damage as measured by the SLICC\/ACR damage index is a predictor of mortality in systemic lupus erythematosus","volume":"10","author":"Rahman","year":"2001","journal-title":"Lupus"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0010","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/1529-0131(200104)45:2<191::AID-ANR173>3.0.CO;2-2","article-title":"Systemic lupus erythematosus in three ethnic groups.VII [correction of VIII]. Predictors of early mortality in the LUMINA cohort. LUMINA Study Group","volume":"45","author":"Alarcon","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0011","first-page":"1398","article-title":"High predictive value of the Systemic Lupus International Collaborating Clinics\/American College of Rheumatology damage index for survival in systemic lupus erythematosus","volume":"29","author":"Nived","year":"2002","journal-title":"J Rheumatol"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0012","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1177\/0961203308093829","article-title":"Initial and accrued damage as predictors of mortality in Brazilian patients with systemic lupus erythematosus: a cohort study","volume":"17","author":"Cardoso","year":"2008","journal-title":"Lupus"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0013","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/rheumatology\/kep062","article-title":"Damage and mortality in a group of British patients with systemic lupus erythematosus followed up for over 10 years","volume":"48","author":"Chambers","year":"2009","journal-title":"Rheumatology"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0014","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1136\/annrheumdis-2013-205171","article-title":"Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort","volume":"74","author":"Bruce","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0015","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1093\/rheumatology\/keu412","article-title":"Birmingham SLE cohort: outcomes of a large inception cohort followed for up to 21 years","volume":"54","author":"Yee","year":"2015","journal-title":"Rheumatology"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0016","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/rheumatology\/35.3.248","article-title":"SLICC\/ACR damage index is valid, and renal and pulmonary organ scores are predictors of severe outcome in patients with systemic lupus erythematosus","volume":"35","author":"Stoll","year":"1996","journal-title":"Br J Rheumatol"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0017","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1093\/rheumatology\/kep012","article-title":"Renal damage is the most important predictor of mortality within the damage index: data from LUMINA LXIV, a multiethnic US cohort","volume":"48","author":"Danila","year":"2009","journal-title":"Rheumatology"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0018","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1093\/rheumatology\/kew049","article-title":"Relationship between damage clustering and mortality in systemic lupus erythematosus in early and late stages of the disease: cluster analyses in a large cohort from the Spanish Society of Rheumatology Lupus Registry","volume":"55","author":"Pego-Reigosa","year":"2016","journal-title":"Rheumatology"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0019","first-page":"873","article-title":"The relevance of cluster analyses to stratify systemic lupus erythematosus: increased mortality with heavier treatment","volume":"35","author":"De Marchi","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0020","first-page":"1047","volume":"35","author":"Torrente-Segarra","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.semarthrit.2018.09.005_bib0021","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1002\/acr.23199","article-title":"From childhood to adulthood: the trajectory of damage in patients with juvenile-onset systemic lupus erythematosus","volume":"69","author":"Lim","year":"2017","journal-title":"Arthritis Care Res"}],"container-title":["Seminars in Arthritis and Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017218303391?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017218303391?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T16:59:24Z","timestamp":1758733164000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049017218303391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S0049017218303391"],"URL":"https:\/\/doi.org\/10.1016\/j.semarthrit.2018.09.005","relation":{},"ISSN":["0049-0172"],"issn-type":[{"value":"0049-0172","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between damage and mortality in juvenile-onset systemic lupus erythematosus: Cluster analyses in a large cohort from the Spanish Society of Rheumatology Lupus Registry (RELESSER)","name":"articletitle","label":"Article Title"},{"value":"Seminars in Arthritis and Rheumatism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semarthrit.2018.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}