{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T11:37:39Z","timestamp":1790422659263,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Arthritis and Rheumatism"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.semarthrit.2022.152033","type":"journal-article","created":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T11:03:48Z","timestamp":1653735828000},"page":"152033","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Left ventricular diastolic dysfunction in systemic sclerosis: Clinical, immunological and survival differences in the Spanish RESCLE registry"],"prefix":"10.1016","volume":"55","author":[{"given":"Andr\u00e9s","family":"Gonz\u00e1lez Garc\u00eda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Fabregate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Manzano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Guill\u00e9n del Castillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Rubio Rivas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Argibay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adela","family":"Mar\u00edn Ballv\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignasi","family":"Rodr\u00edguez Pint\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Pla Salas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bego\u00f1a","family":"Mar\u00ed-Alfonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Callejas Moraga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dolores","family":"Colunga Arg\u00fcelles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"S\u00e1ez Comet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Gonz\u00e1lez-Ech\u00e1varri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norberto","family":"Ortego-Centeno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"Vargas Hitos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Antonio","family":"Todol\u00ed Parra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Trapiella Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Teresa","family":"Herranz Mar\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayka","family":"Freire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio-J","family":"Chamorro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Perales Fraile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Bel\u00e9n","family":"Madro\u00f1ero Vuelta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabela","family":"S\u00e1nchez Trigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carles","family":"Tolosa Vilella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicent","family":"Fonollosa Pla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen Pilar","family":"Sime\u00f3n Aznar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semarthrit.2022.152033_bib0001","doi-asserted-by":"crossref","first-page":"15002","DOI":"10.1038\/nrdp.2015.2","article-title":"Systemic sclerosis","volume":"1","author":"Allanore","year":"2015","journal-title":"Nat Rev Dis Prim"},{"key":"10.1016\/j.semarthrit.2022.152033_bib0002","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s41927-018-0043-6","article-title":"Trends in incidence, mortality, and causes of death associated with systemic sclerosis in Denmark between 1995 and 2015: a nationwide cohort study","volume":"2","author":"Butt","year":"2018","journal-title":"BMC Rheumatol"},{"issue":"5","key":"10.1016\/j.semarthrit.2022.152033_bib0003","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1016\/j.semarthrit.2018.07.008","article-title":"Defining primary systemic sclerosis heart involvement: a scoping literature review","volume":"48","author":"Ross","year":"2019","journal-title":"Semin Arthritis Rheum"},{"issue":"2","key":"10.1016\/j.semarthrit.2022.152033_bib0004","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.semarthrit.2014.05.010","article-title":"Mortality and survival in systemic sclerosis: systematic review and meta-analysis","volume":"44","author":"Rubio-Rivas","year":"2014","journal-title":"Semin Arthritis Rheum"},{"issue":"6","key":"10.1016\/j.semarthrit.2022.152033_bib0005","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/rheumatology\/keq022","article-title":"Construct validity evaluation of the European Scleroderma Study Group activity index, and investigation of possible new disease activity markers in systemic sclerosis","volume":"49","author":"Minier","year":"2010","journal-title":"Rheumatology"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0006","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.rdc.2013.10.007","article-title":"Systemic sclerosis and the heart","volume":"40","author":"Parks","year":"2014","journal-title":"Rheum Dis Clin N Am"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0007","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1136\/ard.2006.057760","article-title":"Evaluation of cardiac abnormalities by Doppler echocardiography in a large nationwide multicentric cohort of patients with systemic sclerosis","volume":"67","author":"de Groote","year":"2008","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.1016\/j.semarthrit.2022.152033_bib0008","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.semarthrit.2014.04.001","article-title":"Five-year follow-up of left ventricular diastolic function in systemic sclerosis patients: determinants of mortality and disease progression","volume":"44","author":"Faludi","year":"2014","journal-title":"Semin Arthritis Rheum"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0009","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00296-015-3382-2","article-title":"Cardiac involvement in systemic sclerosis: differences between clinical subsets and influence on survival","volume":"37","author":"Fernandez-Codina","year":"2017","journal-title":"Rheumatol Int"},{"issue":"4","key":"10.1016\/j.semarthrit.2022.152033_bib0010","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1080\/03009742.2016.1206963","article-title":"Prevalence and risk factors for left ventricular diastolic dysfunction in a scleroderma cohort","volume":"46","author":"Vemulapalli","year":"2017","journal-title":"Scand J Rheumatol"},{"issue":"3","key":"10.1016\/j.semarthrit.2022.152033_bib0011","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/eurjhf\/hfp198","article-title":"Cardiac Raynaud's phenomenon induced by cold provocation as a predictor of long-term left ventricular dysfunction and remodelling in systemic sclerosis: 7-year follow-up study","volume":"12","author":"Mizuno","year":"2010","journal-title":"Eur J Heart fail"},{"issue":"4","key":"10.1016\/j.semarthrit.2022.152033_bib0012","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1183\/09031936.00091212","article-title":"High prevalence of occult left heart disease in scleroderma-pulmonary hypertension","volume":"42","author":"Fox","year":"2013","journal-title":"Eur Respir J"},{"key":"10.1016\/j.semarthrit.2022.152033_bib0013","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ijcard.2018.03.020","article-title":"Fluid challenge predicts clinical worsening in pulmonary arterial hypertension","volume":"261","author":"D'Alto","year":"2018","journal-title":"Int J Cardiol"},{"issue":"2","key":"10.1016\/j.semarthrit.2022.152033_bib0014","first-page":"S30","article-title":"Prevalence, prognosis, and factors associated with left ventricular diastolic dysfunction in systemic sclerosis","volume":"30","author":"Hinchcliff","year":"2012","journal-title":"Clin Exp Rheumatol"},{"issue":"5","key":"10.1016\/j.semarthrit.2022.152033_bib0015","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jacc.2013.10.063","article-title":"Pre-clinical diastolic dysfunction","volume":"63","author":"Wan","year":"2014","journal-title":"J Am Coll Cardiol"},{"issue":"6","key":"10.1016\/j.semarthrit.2022.152033_bib0016","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.semarthrit.2011.10.004","article-title":"Registry of the Spanish network for systemic sclerosis: clinical pattern according to cutaneous subsets and immunological status","volume":"41","author":"Simeon-Aznar","year":"2012","journal-title":"Semin Arthritis Rheum"},{"issue":"8","key":"10.1016\/j.semarthrit.2022.152033_bib0017","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.autrev.2017.05.013","article-title":"Very early and early systemic sclerosis in the Spanish scleroderma registry (RESCLE) cohort","volume":"16","author":"Trapiella-Martinez","year":"2017","journal-title":"Autoimmun Rev"},{"issue":"3","key":"10.1016\/j.semarthrit.2022.152033_bib0018","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/eurheartj\/ehz425","article-title":"ESC Guidelines for the diagnosis and management of chronic coronary syndromes: the task force for the diagnosis and management of chronic coronary syndromes of the European society of cardiology (ESC)","volume":"41","author":"Knuuti","year":"2019","journal-title":"Eur Heart J"},{"issue":"42","key":"10.1016\/j.semarthrit.2022.152033_bib0019","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1093\/eurheartj\/ehv318","volume":"36","author":"Adler","year":"2015","journal-title":"Eur Heart J"},{"issue":"7","key":"10.1016\/j.semarthrit.2022.152033_bib0020","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1093\/ehjci\/jet105","article-title":"Recommendations for the echocardiographic assessment of native valvular regurgitation: an executive summary from the European Association of Cardiovascular Imaging","volume":"14","author":"Lancellotti","year":"2013","journal-title":"Eur Heart J Cardiovasc Imaging"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0021","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1093\/eurheartj\/ehv317","volume":"37","author":"Galie","year":"2015","journal-title":"Eur Heart J"},{"issue":"6","key":"10.1016\/j.semarthrit.2022.152033_bib0022","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1136\/ard.2006.062901","article-title":"Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR scleroderma trials and research group database","volume":"66","author":"Walker","year":"2007","journal-title":"Ann Rheum Dis"},{"issue":"4-5","key":"10.1016\/j.semarthrit.2022.152033_bib0023","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s10741-011-9270-2","article-title":"Age-associated changes in cardiovascular structure and function: a fertile milieu for future disease","volume":"17","author":"Fleg","year":"2012","journal-title":"Heart Fail Rev"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0024","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1136\/ard.2008.103382","article-title":"Prevalence and factors associated with left ventricular dysfunction in the EULAR scleroderma trial and research group (EUSTAR) database of patients with systemic sclerosis","volume":"69","author":"Allanore","year":"2010","journal-title":"Ann Rheum Dis"},{"issue":"15","key":"10.1016\/j.semarthrit.2022.152033_bib0025","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.jacc.2018.07.068","article-title":"Left ventricular diastolic dysfunction predicts mortality in patients with systemic sclerosis","volume":"72","author":"Tennoe","year":"2018","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.semarthrit.2022.152033_bib0026","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.3899\/jrheum.100956","article-title":"Late-age onset systemic sclerosis","volume":"38","author":"Manno","year":"2011","journal-title":"J Rheumatol"},{"issue":"9","key":"10.1016\/j.semarthrit.2022.152033_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102602","article-title":"Factors associated with pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc)","volume":"19","author":"Jiang","year":"2020","journal-title":"Autoimmun Rev"},{"issue":"11","key":"10.1016\/j.semarthrit.2022.152033_bib0028","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1136\/annrheumdis-2019-215486","article-title":"Vasodilators and low-dose acetylsalicylic acid are associated with a lower incidence of distinct primary myocardial disease manifestations in systemic sclerosis: results of the DeSScipher inception cohort study","volume":"78","author":"Valentini","year":"2019","journal-title":"Ann Rheum Dis"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0029","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13075-020-2141-2","article-title":"ACE inhibitors in SSc patients display a risk factor for scleroderma renal crisis-a EUSTAR analysis","volume":"22","author":"Butikofer","year":"2020","journal-title":"Arthritis Res Ther"},{"issue":"5","key":"10.1016\/j.semarthrit.2022.152033_bib0030","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1002\/art.42054","article-title":"Diastolic dysfunction in systemic sclerosis: risk factors and impact on mortality","volume":"74","author":"Hinze","year":"2022","journal-title":"Arthritis Rheumatol"},{"issue":"9","key":"10.1016\/j.semarthrit.2022.152033_bib0031","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1136\/ard.2004.031484","article-title":"Evaluation of the effect of nifedipine upon myocardial perfusion and contractility using cardiac magnetic resonance imaging and tissue Doppler echocardiography in systemic sclerosis","volume":"64","author":"Vignaux","year":"2005","journal-title":"Ann Rheum Dis"},{"issue":"3","key":"10.1016\/j.semarthrit.2022.152033_bib0032","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1136\/annrheumdis-2012-202295","article-title":"Very early versus early disease: the evolving definition of the 'many faces' of systemic sclerosis","volume":"72","author":"Matucci-Cerinic","year":"2013","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"10.1016\/j.semarthrit.2022.152033_bib0033","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nrrheum.2009.238","article-title":"Autoantibodies as predictive tools in systemic sclerosis","volume":"6","author":"Nihtyanova","year":"2010","journal-title":"Nat Rev Rheumatol"},{"issue":"6","key":"10.1016\/j.semarthrit.2022.152033_bib0034","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.semarthrit.2017.10.004","article-title":"Hepatobiliary involvement in systemic sclerosis and the cutaneous subsets: Characteristics and survival of patients from the Spanish RESCLE Registry","volume":"47","author":"Mari-Alfonso","year":"2018","journal-title":"Semin Arthritis Rheum"},{"issue":"4","key":"10.1016\/j.semarthrit.2022.152033_bib0035","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.semarthrit.2021.05.019","article-title":"Muscle pathological features and extra-muscle involvement in idiopathic inflammatory myopathies with anti-mitochondrial antibody","volume":"51","author":"Zhang","year":"2021","journal-title":"Semin Arthritis Rheum"},{"issue":"6","key":"10.1016\/j.semarthrit.2022.152033_bib0036","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/BOR.0000000000000552","article-title":"Muscle disease in scleroderma","volume":"30","author":"Paik","year":"2018","journal-title":"Curr Opin Rheumatol"},{"issue":"7","key":"10.1016\/j.semarthrit.2022.152033_bib0037","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.3899\/jrheum.201005","article-title":"Increased risk of valvular heart disease in systemic sclerosis: an underrecognized cardiac complication","volume":"48","author":"Kurmann","year":"2021","journal-title":"J Rheumatol"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0038","doi-asserted-by":"crossref","first-page":"e95","DOI":"10.1097\/RHU.0000000000001638","article-title":"Heart valve abnormalities in systemic sclerosis patients: a multicenter cohort study and review of the literature","volume":"28","author":"Colaci","year":"2022","journal-title":"J Clin Rheumatol"},{"issue":"1","key":"10.1016\/j.semarthrit.2022.152033_bib0039","doi-asserted-by":"crossref","first-page":"38","DOI":"10.7326\/0003-4819-94-1-38","article-title":"The prevalence of conduction defects and cardiac arrhythmias in progressive systemic sclerosis","volume":"94","author":"Roberts","year":"1981","journal-title":"Ann Intern Med"},{"issue":"7","key":"10.1016\/j.semarthrit.2022.152033_bib0040","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1093\/rheumatology\/ket377","article-title":"Cardiac arrhythmias and conduction defects in systemic sclerosis","volume":"53","author":"Vacca","year":"2014","journal-title":"Rheumatology"},{"issue":"35","key":"10.1016\/j.semarthrit.2022.152033_bib0041","first-page":"40","article-title":"Changes in the pattern of death of 987 patients with systemic sclerosis from 1990 to 2009 from the nationwide Spanish Scleroderma Registry (RESCLE)","volume":"106","author":"Rubio-Rivas","year":"2017","journal-title":"Clin Exp Rheumatol"},{"issue":"10","key":"10.1016\/j.semarthrit.2022.152033_bib0042","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1136\/ard.2009.114264","article-title":"Causes and risk factors for death in systemic sclerosis: a study from the EULAR scleroderma trials and research (EUSTAR) database","volume":"69","author":"Tyndall","year":"2010","journal-title":"Ann Rheum Dis"},{"issue":"3","key":"10.1016\/j.semarthrit.2022.152033_bib0043","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00296-017-3916-x","article-title":"Interstitial lung disease in systemic sclerosis: data from the spanish scleroderma study group","volume":"38","author":"Sanchez-Cano","year":"2018","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.semarthrit.2022.152033_bib0044","doi-asserted-by":"crossref","unstructured":"Noviani M., Saffari S.E., Tan J.L., Yip J.W.L., Teng G.G., Law W.G., et\u00a0al. Mortality and hospitalization outcomes of interstitial lung disease and pulmonary hypertension in the Singapore systemic sclerosis cohort. Semin Arthritis Rheum 2019. doi:10.1016\/j.semarthrit.2019.11.005.","DOI":"10.1016\/j.semarthrit.2019.11.005"},{"issue":"6","key":"10.1016\/j.semarthrit.2022.152033_bib0045","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1378\/chest.11-1903","article-title":"Prevalence and prognostic value of left ventricular diastolic dysfunction in idiopathic and heritable pulmonary arterial hypertension","volume":"141","author":"Tonelli","year":"2012","journal-title":"Chest"},{"issue":"25","key":"10.1016\/j.semarthrit.2022.152033_bib0046","doi-asserted-by":"crossref","first-page":"D100","DOI":"10.1016\/j.jacc.2013.10.033","article-title":"Pulmonary hypertension due to left heart diseases","volume":"62","author":"Vachiery","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.semarthrit.2022.152033_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.semarthrit.2020.02.013","article-title":"An evidence-based strategy to screen for pulmonary arterial hypertension in systemic sclerosis","author":"Semalulu","year":"2020","journal-title":"Semin Arthritis Rheum"},{"issue":"45","key":"10.1016\/j.semarthrit.2022.152033_bib0048","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/rheumatology\/kel312","article-title":"Primary myocardial involvement in systemic sclerosis","author":"Kahan","year":"2006","journal-title":"Rheumatology"},{"issue":"2","key":"10.1016\/j.semarthrit.2022.152033_bib0049","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.echo.2019.09.022","article-title":"The association between left ventricular diastolic dysfunction and myocardial scar and their collective impact on all-cause mortality","volume":"33","author":"Wang","year":"2020","journal-title":"J Am Soc Echocardiogr Off Publ Am Soc Echocardiogr"},{"issue":"11","key":"10.1016\/j.semarthrit.2022.152033_bib0050","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1016\/j.jcmg.2019.05.017","article-title":"Clinical and echocardiographic associates of all-cause mortality and cardiovascular outcomes in patients with systemic sclerosis","volume":"12","author":"van Wijngaarden","year":"2019","journal-title":"JACC Cardiovasc Imaging"}],"container-title":["Seminars in Arthritis and Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017222000841?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0049017222000841?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T17:11:20Z","timestamp":1758733880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0049017222000841"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":50,"alternative-id":["S0049017222000841"],"URL":"https:\/\/doi.org\/10.1016\/j.semarthrit.2022.152033","relation":{},"ISSN":["0049-0172"],"issn-type":[{"value":"0049-0172","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Left ventricular diastolic dysfunction in systemic sclerosis: Clinical, immunological and survival differences in the Spanish RESCLE registry","name":"articletitle","label":"Article Title"},{"value":"Seminars in Arthritis and Rheumatism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semarthrit.2022.152033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"152033"}}