{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:12:17Z","timestamp":1790874737887,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"am","delay-in-days":335,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZIA ES101081"],"award-info":[{"award-number":["ZIA ES101081"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000883","name":"University of Bristol","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000883","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014653","name":"Manchester Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR203308"],"award-info":[{"award-number":["NIHR203308"]}],"id":[{"id":"10.13039\/100014653","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Arthritis and Rheumatism"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.semarthrit.2025.152858","type":"journal-article","created":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T18:58:43Z","timestamp":1761591523000},"page":"152858","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Analytical performance of commercial myositis-specific autoantibody tests evaluated against immunoprecipitation assays as a reference standard: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2593-1771","authenticated-orcid":false,"given":"Takahisa","family":"Gono","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Gil-Vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Selva-O\u2019Callaghan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annet","family":"van Royen-Kerkhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anett","family":"Vincze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Mecoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"G\u00f3mez-Mart\u00edn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00f6rte","family":"Hamann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Conticini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Griger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Jiram","family":"Torres-Ruiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D","family":"Pauling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector","family":"Chinoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Latika","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levente","family":"Bodoki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noreen","family":"Nasir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallavi Pimpale","family":"Chavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raju","family":"Khubchandani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trallero-Aragu\u00e1s","family":"Ernesto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhito","family":"Hamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa G.","family":"Rider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Tansley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"R\u00f6nnelid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8352-6136","authenticated-orcid":false,"given":"Masataka","family":"Kuwana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil J","family":"McHugh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0001","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/s41584-024-01188-4","article-title":"An update on autoantibodies in the idiopathic inflammatory myopathies","volume":"21","author":"Allameen","year":"2025","journal-title":"Nat Rev Rheumatol"},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0002","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/1744666X.2019.1699059","article-title":"Current understanding and recent advances in myositis-specific and -associated autoantibodies detected in patients with dermatomyositis","volume":"16","author":"Gono","year":"2020","journal-title":"Expert Rev Clin Immunol"},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0003","doi-asserted-by":"crossref","DOI":"10.1186\/s13075-020-02210-2","article-title":"The promise, perceptions, and pitfalls of immunoassays for autoantibody testing in myositis","volume":"22","author":"Tansley","year":"2020","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0005","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0006","unstructured":"Macaskill P., Gatsonis C., Deeks J., Harbord R., Takwoingi Y. Chapter 10 analysing and presenting results. https:\/\/training.cochrane.org\/handbook-diagnostic-test-accuracy."},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0007","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1007\/s11606-012-2021-9","article-title":"Chapter 7: grading a body of evidence on diagnostic tests","volume":"27","author":"Singh","year":"2012","journal-title":"J Gen Intern Med"},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0008","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"issue":"3","key":"10.1016\/j.semarthrit.2025.152858_bib0009","doi-asserted-by":"crossref","first-page":"313","DOI":"10.2169\/internalmedicine.7824-21","article-title":"A comparison of line blots, enzyme-linked immunosorbent, and RNA-immunoprecipitation assays of antisynthetase antibodies in serum samples from 44 patients","volume":"61","author":"Shinoda","year":"2022","journal-title":"Intern Med"},{"issue":"12","key":"10.1016\/j.semarthrit.2025.152858_bib0010","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1093\/rheumatology\/keq281","article-title":"Diagnostic performance and validation of autoantibody testing in myositis by a commercial line blot assay","volume":"49","author":"Ghirardello","year":"2010","journal-title":"Rheumatology"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0011","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.975939","article-title":"The use of ELISA is comparable to immunoprecipitation in the detection of selected myositis-specific autoantibodies in a European population","volume":"13","author":"Loganathan","year":"2022","journal-title":"Front Immunol"},{"issue":"8","key":"10.1016\/j.semarthrit.2025.152858_bib0012","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1093\/rheumatology\/keaa021","article-title":"The reliability of immunoassays to detect autoantibodies in patients with myositis is dependent on autoantibody specificity","volume":"59","author":"Tansley","year":"2020","journal-title":"Rheumatology"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jim.2016.02.017","article-title":"Testing for myositis specific autoantibodies: comparison between line blot and immunoprecipitation assays in 57 myositis sera","volume":"433","author":"Cavazzana","year":"2016","journal-title":"J Immunol Methods"},{"issue":"8","key":"10.1016\/j.semarthrit.2025.152858_bib0014","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1007\/s00296-023-05287-5","article-title":"Performance of cut-offs adjusted with positive control band intensity in line-blot assays for myositis-specific antibodies","volume":"43","author":"Chang","year":"2023","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0015","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1136\/annrheumdis-2018-214690","article-title":"Comparison of autoantibody specificities tested by a line blot assay and immunoprecipitation-based algorithm in patients with idiopathic inflammatory myopathies","volume":"78","author":"Espinosa-Ortega","year":"2019","journal-title":"Ann Rheum Dis"},{"issue":"11","key":"10.1016\/j.semarthrit.2025.152858_bib0016","doi-asserted-by":"crossref","first-page":"3489","DOI":"10.1007\/s10067-020-04973-0","article-title":"Performance evaluation of a commercial line blot assay system for detection of myositis- and systemic sclerosis-related autoantibodies","volume":"39","author":"Hamaguchi","year":"2020","journal-title":"Clin Rheumatol"},{"issue":"9","key":"10.1016\/j.semarthrit.2025.152858_bib0017","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1093\/rheumatology\/keae167","article-title":"Assessing the sensitivity and specificity of myositis-specific and associated autoantibodies: a sub-study from the MyoCite cohort","volume":"63","author":"Loganathan","year":"2024","journal-title":"Rheumatology"},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0018","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/art.41088","article-title":"Myositis autoantibodies: a comparison of results from the oklahoma medical research foundation myositis panel to the Euroimmun research Line Blot","volume":"72","author":"Mecoli","year":"2020","journal-title":"Arthritis Rheumatol"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.jim.2019.112661","article-title":"Evaluation of a novel particle-based assay for detection of autoantibodies in idiopathic inflammatory myopathies","volume":"474","author":"Cavazzana","year":"2019","journal-title":"J Immunol Methods"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0020","doi-asserted-by":"crossref","first-page":"848","DOI":"10.3389\/fimmu.2019.00848","article-title":"Comparison of three immunoassays for the detection of myositis specific antibodies","volume":"10","author":"Mahler","year":"2019","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.semarthrit.2025.152858_bib0021","first-page":"1048","article-title":"Distinct dermatomyositis populations are detected with different autoantibody assay platforms","volume":"37","author":"Fiorentino","year":"2019","journal-title":"Clin Exp Rheumatol"},{"issue":"3","key":"10.1016\/j.semarthrit.2025.152858_bib0022","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.jdermsci.2016.09.013","article-title":"Enzyme-linked immunosorbent assays for detection of anti-transcriptional intermediary factor-1 gamma and anti-mi-2 autoantibodies in dermatomyositis","volume":"84","author":"Fujimoto","year":"2016","journal-title":"J Dermatol Sci"},{"issue":"5","key":"10.1016\/j.semarthrit.2025.152858_bib0023","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/acr2.11247","article-title":"A North American cohort of Anti-SAE dermatomyositis: clinical phenotype, testing, and review of cases","volume":"3","author":"Albayda","year":"2021","journal-title":"ACR Open Rheumatol"},{"issue":"3","key":"10.1016\/j.semarthrit.2025.152858_bib0024","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s12026-018-9006-7","article-title":"Antibodies to small ubiquitin-like modifier activating enzyme are associated with a diagnosis of dermatomyositis: results from an unselected cohort","volume":"66","author":"Peterson","year":"2018","journal-title":"Immunol Res"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0025","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.804037","article-title":"A commercial anti-TIF1\u03b3 ELISA is superior to line and dot blot and should Be considered as part of routine myositis-specific antibody testing","volume":"13","author":"Mulhearn","year":"2022","journal-title":"Front Immunol"},{"issue":"2","key":"10.1016\/j.semarthrit.2025.152858_bib0026","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.jaad.2020.06.088","article-title":"A single-center, retrospective record review of malignancy prevalence in patients with dermatomyositis with anti-transcription intermediary factor 1\u03b3 antibodies via line immunoassay versus immunoprecipitation","volume":"84","author":"Westerdahl","year":"2021","journal-title":"J Am Acad Dermatol"},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0027","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0085062","article-title":"The multicenter study of a new assay for simultaneous detection of multiple anti-aminoacyl-tRNA synthetases in myositis and interstitial pneumonia","volume":"9","author":"Nakashima","year":"2014","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.semarthrit.2025.152858_bib0028","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/mr\/roac056","article-title":"A multianalyte assay for the detection of dermatomyositis-related autoantibodies based on immunoprecipitation combined with immunoblotting","volume":"33","author":"Kuwana","year":"2023","journal-title":"Mod Rheumatol"},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0029","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1080\/14397595.2018.1452179","article-title":"Improved quantification of a commercial enzyme-linked immunosorbent assay kit for measuring anti-MDA5 antibody","volume":"29","author":"Gono","year":"2019","journal-title":"Mod Rheumatol"},{"issue":"4","key":"10.1016\/j.semarthrit.2025.152858_bib0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0154285","article-title":"Clinical utility of an enzyme-linked immunosorbent assay for detecting anti-melanoma differentiation-associated gene 5 autoantibodies","volume":"11","author":"Sato","year":"2016","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.semarthrit.2025.152858_bib0031","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2019.102425","article-title":"Validation of anti-Mi2 autoantibody testing by line blot","volume":"19","author":"Pinal-Fernandez","year":"2020","journal-title":"Autoimmun Rev"},{"issue":"19","key":"10.1016\/j.semarthrit.2025.152858_bib0032","doi-asserted-by":"crossref","DOI":"10.3390\/diagnostics13193080","article-title":"Detection of myositis autoantibodies by multi-analytic immunoassays in a large multicenter cohort of patients with definite idiopathic inflammatory myopathies","volume":"13","author":"Ghirardello","year":"2023","journal-title":"Diagnostics"},{"issue":"2","key":"10.1016\/j.semarthrit.2025.152858_bib0033","first-page":"277","article-title":"Agreement between local and central anti-synthetase antibodies detection: results from the Classification Criteria of Anti-Synthetase Syndrome project biobank","volume":"42","author":"Loganathan","year":"2024","journal-title":"Clin Exp Rheumatol"},{"issue":"2","key":"10.1016\/j.semarthrit.2025.152858_bib0034","doi-asserted-by":"crossref","first-page":"212","DOI":"10.55563\/clinexprheumatol\/3cuc1s","article-title":"Pitfalls in the detection of myositis specific antibodies by lineblot in clinically suspected idiopathic inflammatory myopathy","volume":"38","author":"Piette","year":"2020","journal-title":"Clin Exp Rheumatol"},{"key":"10.1016\/j.semarthrit.2025.152858_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtauto.2019.100013","article-title":"Frequencies and clinical associations of myositis-related antibodies in The Netherlands: a one-year survey of all Dutch patients","volume":"2","author":"Platteel","year":"2019","journal-title":"J Transl Autoimmun"}],"container-title":["Seminars in Arthritis and Rheumatism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004901722500229X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004901722500229X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T07:38:53Z","timestamp":1773905933000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004901722500229X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":35,"alternative-id":["S004901722500229X"],"URL":"https:\/\/doi.org\/10.1016\/j.semarthrit.2025.152858","relation":{},"ISSN":["0049-0172"],"issn-type":[{"value":"0049-0172","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analytical performance of commercial myositis-specific autoantibody tests evaluated against immunoprecipitation assays as a reference standard: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Seminars in Arthritis and Rheumatism","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semarthrit.2025.152858","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"152858"}}