{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T18:44:04Z","timestamp":1791398644514,"version":"4.3.3"},"reference-count":158,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100011371","name":"Royal Australasian College of Surgeons","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011371","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Cancer Biology"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.semcancer.2020.05.012","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T21:55:10Z","timestamp":1591739710000},"page":"86-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["Liver regeneration and liver metastasis"],"prefix":"10.1016","volume":"71","author":[{"given":"Georgina E","family":"Riddiough","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qaiser","family":"Jalal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos V","family":"Perini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali W","family":"Majeed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0005","doi-asserted-by":"crossref","first-page":"312","DOI":"10.4236\/ss.2011.26066","article-title":"Effects of surgery and palliative chemotherapy in the treatment of colorectal liver metastasis","volume":"2","author":"Bird","year":"2011","journal-title":"Surg. Sci."},{"issue":"11","key":"10.1016\/j.semcancer.2020.05.012_bib0010","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1002\/jhbp.587","article-title":"Outcomes of 1,639 hepatectomies for non-colorectal non-neuroendocrine liver metastases: a multicenter analysis","volume":"25","author":"Sano","year":"2018","journal-title":"J. Hepatobiliary. Sci."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0015","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1038\/s41598-020-58855-1","article-title":"Diagnostic performance of magnetic resonance imaging for colorectal liver metastasis: a systematic review and meta-analysis","volume":"10","author":"Mao","year":"2020","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.semcancer.2020.05.012_bib0020","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1038\/s41588-019-0423-x","article-title":"Quantitative evidence for early metastatic seeding in colorectal cancer","volume":"51","author":"Hu","year":"2019","journal-title":"Nat. Genet."},{"issue":"6378","key":"10.1016\/j.semcancer.2020.05.012_bib0025","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1126\/science.aar3247","article-title":"Detection and localization of surgically resectable cancers with a multi-analyte blood test","volume":"359","author":"Cohen","year":"2018","journal-title":"Science."},{"issue":"12","key":"10.1016\/j.semcancer.2020.05.012_bib0030","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1001\/archsurg.142.12.1144","article-title":"A second liver resection due to recurrent colorectal liver metastases","volume":"142","author":"Sa Cunha","year":"2007","journal-title":"Arch Surg. American Medical Association"},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0035","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1007\/s00595-010-4471-1","article-title":"Risk factors for early recurrence after curative hepatectomy for colorectal liver metastases","volume":"41","author":"Yamashita","year":"2011","journal-title":"Surg Today"},{"issue":"60","key":"10.1016\/j.semcancer.2020.05.012_bib0040","doi-asserted-by":"crossref","first-page":"102531","DOI":"10.18632\/oncotarget.20934","article-title":"A postoperative scoring system for post-hepatectomy early recurrence of colorectal liZ.-Y. Metastases","volume":"8","author":"Mao","year":"2017","journal-title":"Oncotarget."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0045","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1097\/00000658-199610000-00009","article-title":"Resection of nonresectable liver metastases from colorectal cancer after neoadjuvant chemotherapy","volume":"224","author":"Bismuth","year":"1996","journal-title":"Ann. Surg."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0050","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/path.1544","article-title":"Do metastases metastasize?","volume":"203","author":"Tait","year":"2004","journal-title":"J Pathol."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0055","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0002-9610(75)90473-0","article-title":"Metastasis of metastases","volume":"130","author":"Hoover","year":"1975","journal-title":"Am. J. Surg."},{"issue":"7\u20138","key":"10.1016\/j.semcancer.2020.05.012_bib0060","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/ans.14405","article-title":"Sentinel lymph node mapping in liver resection for colorectal liver metastases","volume":"89","author":"Perini","year":"2019","journal-title":"ANZ J. Surg."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0065","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/00000658-199909000-00004","article-title":"Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases","volume":"230","author":"Fong","year":"1999","journal-title":"Ann Surg."},{"issue":"45","key":"10.1016\/j.semcancer.2020.05.012_bib0070","doi-asserted-by":"crossref","first-page":"79927","DOI":"10.18632\/oncotarget.20322","article-title":"Long-term postoperative survival prediction in patients with colorectal liver metastasis","volume":"8","author":"Wang","year":"2017","journal-title":"Oncotarget."},{"issue":"8","key":"10.1016\/j.semcancer.2020.05.012_bib0075","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1111\/jgh.14644","article-title":"Searching for the link; mechanisms underlying liver regeneration and recurrence of colorectal liver metastasis post partial hepatectomy","volume":"34","author":"Riddiough","year":"2019","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0080","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1002\/hep.28988","article-title":"Hepatostat: liver regeneration and normal liver tissue maintenance","volume":"65","author":"Michalopoulos","year":"2017","journal-title":"Hepatology."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0085","doi-asserted-by":"crossref","first-page":"68","DOI":"10.4161\/org.4.2.5851","article-title":"Wnt signal transduction pathways","volume":"4","author":"Komiya","year":"2008","journal-title":"Organogenesis"},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0090","doi-asserted-by":"crossref","first-page":"50","DOI":"10.3390\/cancers8050050","article-title":"Frizzled7: a promising Achilles\u2019 heel for targeting the Wnt receptor complex to treat cancer","volume":"8","author":"Phesse","year":"2016","journal-title":"Cancers (Basel)"},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0095","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.3390\/ijms19051543","article-title":"Frizzled receptors as potential therapeutic targets in human cancers","volume":"19","author":"Zeng","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0100","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1146\/annurev-pathol-020117-044010","article-title":"Wnt\/\u03b2-Catenin signaling in liver development, homeostasis, and Pathobiology","volume":"13","author":"Russell","year":"2017","journal-title":"Annu Rev Pathol."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0105","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1053\/jhep.2001.23786","article-title":"Changes in WNT\/beta-catenin pathway during regulated growth in rat liver regeneration","volume":"33","author":"Monga","year":"2001","journal-title":"Hepatology"},{"issue":"8","key":"10.1016\/j.semcancer.2020.05.012_bib0110","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1016\/j.ajpath.2015.04.021","article-title":"WNT5A inhibits hepatocyte proliferation and concludes \u03b2-catenin signaling in liver regeneration","volume":"185","author":"Yang","year":"2015","journal-title":"Am. J. Pathol."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0115","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.cell.2017.05.016","article-title":"Wnt\/\u03b2-catenin signaling, disease, and emerging therapeutic modalities","volume":"169","author":"Nusse","year":"2017","journal-title":"Cell."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0120","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1002\/dvdy.24527","article-title":"Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells","volume":"247","author":"Schwab","year":"2018","journal-title":"Dev Dyn."},{"issue":"7","key":"10.1016\/j.semcancer.2020.05.012_bib0125","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1053\/j.gastro.2015.02.056","article-title":"\u0392-catenin signaling and roles in liver homeostasis, injury, and tumorigenesis","volume":"148","author":"Monga","year":"2015","journal-title":"Gastroenterology."},{"issue":"46","key":"10.1016\/j.semcancer.2020.05.012_bib0130","doi-asserted-by":"crossref","first-page":"17524","DOI":"10.1074\/jbc.RA119.009979","article-title":"\u03b2-Catenin mutations as determinants of hepatoblastoma phenotypes in mice","volume":"294","author":"Zhang","year":"2019","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0135","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1053\/j.gastro.2014.05.004","article-title":"Activation of \u03b2-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice","volume":"147","author":"Tao","year":"2014","journal-title":"Gastroenterology."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0140","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1038\/ng0797-243","article-title":"Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1","volume":"16","author":"Li","year":"1997","journal-title":"Nat Genet."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0145","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1086\/505332","article-title":"NOTCH2 mutations cause alagille syndrome, a heterogeneous disorder of the notch signaling pathway","volume":"79","author":"McDaniell","year":"2006","journal-title":"Am. J. Hum. Genet."},{"issue":"38","key":"10.1016\/j.semcancer.2020.05.012_bib0150","doi-asserted-by":"crossref","first-page":"5148","DOI":"10.1038\/onc.2008.229","article-title":"The many facets of Notch ligands","volume":"27","author":"D\u2019Souza","year":"2008","journal-title":"Oncogene."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0155","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1002\/hep.20156","article-title":"Expression of Notch-1 and its ligand Jagged-1 in rat liver during liver regeneration","volume":"39","author":"K\u00f6hler","year":"2004","journal-title":"Hepatology"},{"issue":"23","key":"10.1016\/j.semcancer.2020.05.012_bib0160","doi-asserted-by":"crossref","first-page":"4061","DOI":"10.1242\/dev.052118","article-title":"Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome","volume":"137","author":"Hofmann","year":"2010","journal-title":"Development"},{"issue":"11","key":"10.1016\/j.semcancer.2020.05.012_bib0165","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1161\/01.RES.0000266408.42939.e4","article-title":"Notch signaling in blood vessels: who is talking to whom about what?","volume":"100","author":"Hofmann","year":"2007","journal-title":"Circ Res."},{"issue":"7","key":"10.1016\/j.semcancer.2020.05.012_bib0170","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1158\/0008-5472.CAN-13-1467","article-title":"Latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus promotes angiogenesis through targeting notch signaling effector Hey1","volume":"74","author":"Wang","year":"2014","journal-title":"Cancer Res."},{"issue":"10","key":"10.1016\/j.semcancer.2020.05.012_bib0175","article-title":"Inhibition of Notch signaling by a \u03b3-secretase inhibitor attenuates hepatic fibrosis in rats","volume":"7","author":"Chen","year":"2012","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0180","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.ccr.2010.11.008","article-title":"Suppression of colon cancer metastasis by AES through inhibition of Notch signaling","volume":"19","author":"Sonoshita","year":"2011","journal-title":"Cancer Cell"},{"issue":"10","key":"10.1016\/j.semcancer.2020.05.012_bib0185","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s12032-017-1039-6","article-title":"Notch signaling pathway networks in cancer metastasis: a new target for cancer therapy","volume":"34","author":"Li","year":"2017","journal-title":"Med. Oncol."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0190","doi-asserted-by":"crossref","first-page":"G196","DOI":"10.1152\/ajpgi.00077.2014","article-title":"Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration","volume":"307","author":"Grijalva","year":"2014","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0195","doi-asserted-by":"crossref","first-page":"46","DOI":"10.15252\/emmm.201506089","article-title":"Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2","volume":"9","author":"Loforese","year":"2017","journal-title":"EMBO Mol. Med."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0200","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1073\/pnas.0911427107","article-title":"Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver","volume":"107","author":"Lu","year":"2010","journal-title":"Proc Natl Acad Sci."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0205","doi-asserted-by":"crossref","first-page":"e423","DOI":"10.1038\/emm.2017.205","article-title":"Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration","volume":"50","author":"Lu","year":"2018","journal-title":"Exp. Mol. Med."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0210","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.jhep.2014.06.033","article-title":"YAP activation is an early event and a potential therapeutic target in liver cancer development","volume":"61","author":"Perra","year":"2014","journal-title":"J. Hepatol."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0215","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1093\/abbs\/gms084","article-title":"Intersection of Hippo\/YAP and Wnt\/\u03b2-catenin signaling pathways","volume":"45","author":"Konsavage","year":"2013","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"issue":"15","key":"10.1016\/j.semcancer.2020.05.012_bib0220","doi-asserted-by":"crossref","first-page":"11730","DOI":"10.1074\/jbc.M111.327767","article-title":"Wnt\/\u03b2-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells","volume":"287","author":"Konsavage","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0225","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.cell.2014.06.013","article-title":"YAP\/TAZ incorporation in the \u03b2-catenin destruction complex orchestrates the Wnt response","volume":"158","author":"Azzolin","year":"2014","journal-title":"Cell."},{"issue":"12","key":"10.1016\/j.semcancer.2020.05.012_bib0230","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.7150\/ijbs.28089","article-title":"Role of canonical Hedgehog signaling pathway in liver","volume":"14","author":"Gao","year":"2018","journal-title":"Int. J. Biol. Sci."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0235","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1002\/hep.23525","article-title":"Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice","volume":"51","author":"Ochoa","year":"2010","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0240","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jhep.2016.10.014","article-title":"Hedgehog pathway mediates early acceleration of liver regeneration induced by a novel two-staged hepatectomy in mice","volume":"66","author":"Langiewicz","year":"2017","journal-title":"J. Hepatol."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0245","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.jhep.2018.04.017","article-title":"JNK1 induces hedgehog signaling from stellate cells to accelerate liver regeneration in mice","volume":"69","author":"Langiewicz","year":"2018","journal-title":"J. Hepatol."},{"issue":"7","key":"10.1016\/j.semcancer.2020.05.012_bib0250","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1093\/carcin\/bgi378","article-title":"Activation of the hedgehog pathway in human hepatocellular carcinomas","volume":"27","author":"Huang","year":"2006","journal-title":"Carcinogenesis."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0255","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s00432-006-0166-9","article-title":"Dual blockade of the Hedgehog and ERK1\/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells","volume":"133","author":"Jinawath","year":"2007","journal-title":"J Cancer Res Clin Oncol."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0260","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1002\/hep.22649","article-title":"Blocking the hedgehog pathway inhibits hepatoblastoma growth","volume":"49","author":"Eichenm\u00fcller","year":"2009","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0265","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/cas.12354","article-title":"Hedgehog signaling pathway is a potential therapeutic target for gallbladder cancer","volume":"105","author":"Matsushita","year":"2014","journal-title":"Cancer Sci."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0270","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jhep.2017.10.017","article-title":"Hedgehog signalling in liver pathophysiology","volume":"68","author":"Machado","year":"2018","journal-title":"J. Hepatol."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0275","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.jhep.2010.12.043","article-title":"Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations","volume":"55","author":"Chen","year":"2011","journal-title":"J. Hepatol."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0280","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev-pathol-020117-043854","article-title":"Epithelial mesenchymal transition in tumor metastasis","volume":"13","author":"Mittal","year":"2018","journal-title":"Annu. Rev. Pathol."},{"issue":"9","key":"10.1016\/j.semcancer.2020.05.012_bib0285","first-page":"1338","article-title":"Detection of circulating tumour cells with a hybrid (epithelial\/mesenchymal) phenotype in patients with metastatic non-small cell lung cancer","volume":"105","author":"Lecharpentier","year":"2011","journal-title":"Br J Cancer. Nature Publishing Group"},{"issue":"July(4)","key":"10.1016\/j.semcancer.2020.05.012_bib0290","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1007\/s12072-016-9732-7","article-title":"An improved strategy to detect the epithelial-mesenchymal transition process in circulating tumor cells in hepatocellular carcinoma patients","volume":"10","author":"Liu","year":"2016","journal-title":"Hepatol Int. Springer India"},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0295","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.ccr.2013.04.017","article-title":"Tumor cell dissemination: emerging biological insights from animal models and cancer patients","volume":"23","author":"Kang","year":"2013","journal-title":"Cancer Cell"},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0300","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0123976","article-title":"Classification of circulating tumor cells by epithelial-mesenchymal transition markers","volume":"10","author":"Wu","year":"2015","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0305","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.semcancer.2012.02.007","article-title":"Concepts of metastasis in flux: the stromal progression model","volume":"22","author":"Sleeman","year":"2012","journal-title":"Semin. Cancer Biol."},{"key":"10.1016\/j.semcancer.2020.05.012_bib0310","doi-asserted-by":"crossref","first-page":"82","DOI":"10.3389\/fonc.2019.00082","article-title":"Role of microenvironment on the fate of disseminating Cancer stem cells","volume":"9","author":"Ingangi","year":"2019","journal-title":"Front Oncol."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0315","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/2045-824X-3-2","article-title":"Notch modulates VEGF action in endothelial cells by inducing matrix metalloprotease activity","volume":"3","author":"Funahashi","year":"2011","journal-title":"Vasc Cell."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0320","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1471-230X-6-40","article-title":"Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor","volume":"6","author":"Shanmukhappa","year":"2006","journal-title":"BMC Gastroenterol. BioMed Central"},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0325","first-page":"1695","article-title":"Immediate early detection of urokinase receptor after partial hepatectomy and its implications for initiation of liver regeneration","volume":"21","author":"Mars","year":"1995","journal-title":"Hepatology."},{"issue":"Pt 1","key":"10.1016\/j.semcancer.2020.05.012_bib0330","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1042\/BJ20042028","article-title":"Activation of hepatocyte growth factor by urokinase-type plasminogen activator is ionic strength-dependent","volume":"390","author":"Mars","year":"2005","journal-title":"Biochem J."},{"issue":"8","key":"10.1016\/j.semcancer.2020.05.012_bib0335","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/nri1418","article-title":"Matrix metalloproteinases as modulators of inflammation and innate immunity","volume":"4","author":"Parks","year":"2004","journal-title":"Nat Rev Immunol."},{"key":"10.1016\/j.semcancer.2020.05.012_bib0340","doi-asserted-by":"crossref","first-page":"479","DOI":"10.2741\/1811","article-title":"Matrix metalloproteinases: roles in cancer and metastasis","volume":"11","author":"Fingleton","year":"2006","journal-title":"Front Biosci."},{"issue":"3-4","key":"10.1016\/j.semcancer.2020.05.012_bib0345","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1007\/s10555-007-9089-4","article-title":"The other side of MMPs: protective roles in tumor progression","volume":"26","author":"Martin","year":"2007","journal-title":"Cancer Metastasis Rev."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0350","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/0006-291X(84)91253-1","article-title":"Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats","volume":"122","author":"Nakamura","year":"1984","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0355","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/jcp.1041190207","article-title":"Partial characterization of a hepatocyte growth factor from rat platelets","volume":"119","author":"Russell","year":"1984","journal-title":"J Cell Physiol."},{"issue":"5608","key":"10.1016\/j.semcancer.2020.05.012_bib0360","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1126\/science.1079562","article-title":"Angiogenesis-independent endothelial protection of liver: role of VEGFR-1","volume":"299","author":"LeCouter","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.semcancer.2020.05.012_bib0365","first-page":"285","article-title":"The role of Ito cells in the biosynthesis of HGF-SF in the liver","volume":"65","author":"Schirmacher","year":"1993","journal-title":"EXS."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0370","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1002\/hep.510280317","article-title":"Hepatocyte growth factor induces hepatocyte proliferation in vivo and allows for efficient retroviral-mediated gene transfer in mice","volume":"28","author":"Patijn","year":"1998","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0375","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1002\/hep.1840190630","article-title":"Collagenase pretreatment and the mitogenic effects of hepatocyte growth factor and transforming growth factor-alpha in adult rat liver","volume":"19","author":"Liu","year":"1994","journal-title":"Hepatology."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0380","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1002\/hep.1840130422","article-title":"Hepatocyte growth factor (hepatopoietin A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulated by partial hepatectomy and carbon tetrachloride administration","volume":"13","author":"Lindroos","year":"1991","journal-title":"Hepatology."},{"issue":"16","key":"10.1016\/j.semcancer.2020.05.012_bib0385","first-page":"3954","article-title":"Growth factor signal transduction immediately after two-thirds partial hepatectomy in the rat","volume":"59","author":"Stolz","year":"1999","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0390","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/hep.22639","article-title":"Role of overexpression of CD151 and\/or c-Met in predicting prognosis of hepatocellular carcinoma","volume":"49","author":"Ke","year":"2009","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0395","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1172\/JCI27236","article-title":"Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype","volume":"116","author":"Kaposi-Novak","year":"2006","journal-title":"J Clin Invest."},{"issue":"27","key":"10.1016\/j.semcancer.2020.05.012_bib0400","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.2174\/138161212802430521","article-title":"TGF\u03b2 signaling in liver regeneration","volume":"18","author":"Karkampouna","year":"2012","journal-title":"Curr. Pharm. Des."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0405","first-page":"68","article-title":"The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes","volume":"1","author":"Vald\u00e9s","year":"2002","journal-title":"Mol. Cancer Res."},{"issue":"9","key":"10.1016\/j.semcancer.2020.05.012_bib0410","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1038\/ncb434","article-title":"Differentiation plasticity regulated by TGF-beta family proteins in development and disease","volume":"9","author":"Derynck","year":"2007","journal-title":"Nat. Cell Biol."},{"issue":"17","key":"10.1016\/j.semcancer.2020.05.012_bib0415","doi-asserted-by":"crossref","first-page":"2934","DOI":"10.2174\/13816128113199990591","article-title":"TGF-beta signaling in cancer treatment","volume":"20","author":"Fabregat","year":"2014","journal-title":"Curr. Pharm. Des."},{"issue":"7693","key":"10.1016\/j.semcancer.2020.05.012_bib0420","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1038\/nature25492","article-title":"TGF\u03b2 drives immune evasion in genetically reconstituted colon cancer metastasis","volume":"554","author":"Tauriello","year":"2018","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0425","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.cell.2008.07.001","article-title":"TGF beta in cancer","volume":"134","author":"Massagu\u00e9","year":"2008","journal-title":"Cell."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0430","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1002\/hep.1840210531","article-title":"Rapid activation of the Stat3 transcription complex in liver regeneration","volume":"21","author":"Cressman","year":"1995","journal-title":"Hepatology."},{"issue":"9","key":"10.1016\/j.semcancer.2020.05.012_bib0435","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1084\/jem.20131902","article-title":"Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy","volume":"211","author":"Marshall","year":"2014","journal-title":"J. Exp. Med."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0440","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00534-010-0304-2","article-title":"Molecular mechanisms of liver regeneration and protection for treatment of liver dysfunction and diseases","volume":"18","author":"Fujiyoshi","year":"2011","journal-title":"J. Hepatobiliary. Sci."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0445","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1053\/jhep.2003.50318","article-title":"Massive liver growth in mice induced by systemic interleukin 6 administration","volume":"38","author":"Zimmers","year":"2003","journal-title":"Hepatology"},{"issue":"2 Suppl 1","key":"10.1016\/j.semcancer.2020.05.012_bib0450","doi-asserted-by":"crossref","first-page":"S45","DOI":"10.1002\/hep.20969","article-title":"Liver regeneration","volume":"43","author":"Fausto","year":"2006","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0455","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1073\/pnas.94.4.1441","article-title":"Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor","volume":"94","author":"Yamada","year":"1997","journal-title":"PNAS."},{"issue":"32","key":"10.1016\/j.semcancer.2020.05.012_bib0460","doi-asserted-by":"crossref","first-page":"28411","DOI":"10.1074\/jbc.M202807200","article-title":"STAT3 contributes to the mitogenic response of hepatocytes during liver regeneration","volume":"277","author":"Li","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.semcancer.2020.05.012_bib0465","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1038\/nrc1209","article-title":"AP-1: a double-edged sword in tumorigenesis","volume":"3","author":"Eferl","year":"2003","journal-title":"Nat. Rev. Cancer"},{"issue":"16","key":"10.1016\/j.semcancer.2020.05.012_bib0470","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1101\/gad.390506","article-title":"c-Jun\/AP-1 controls liver regeneration by repressing p53\/p21 and p38 MAPK activity","volume":"20","author":"Stepniak","year":"2006","journal-title":"Genes Dev."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0475","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/jcp.21172","article-title":"Liver regeneration","volume":"213","author":"Michalopoulos","year":"2007","journal-title":"J Cell Physiol."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0480","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1002\/lt.22059","article-title":"Portal pressure <15 mm Hg is a key for successful adult living donor liver transplantation utilizing smaller grafts than before","volume":"16","author":"Ogura","year":"2010","journal-title":"Liver Transpl."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0485","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1002\/lt.20317","article-title":"Impact of portal venous pressure on regeneration and graft damage after living-donor liver transplantation","volume":"11","author":"Yagi","year":"2005","journal-title":"Liver Transpl."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0490","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.hpb.2019.10.2445","article-title":"A systematic review of small for size syndrome after major hepatectomy and liver transplantation","volume":"22","author":"Riddiough","year":"2019","journal-title":"HPB"},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0495","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.surg.2004.03.012","article-title":"Effect of portal hemodynamics on liver regeneration studied in a novel portohepatic shunt rat model","volume":"136","author":"Marubashi","year":"2004","journal-title":"Surgery."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0500","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1096\/fasebj.10.4.8647340","article-title":"Liver regeneration 4: transcriptional control of liver regeneration","volume":"10","author":"Taub","year":"1996","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0505","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1055\/s-2007-1007104","article-title":"Transcriptional regulatory signals define cytokine-dependent and -independent pathways in liver regeneration","volume":"19","author":"Taub","year":"1999","journal-title":"Semin Liver Dis."},{"issue":"10","key":"10.1016\/j.semcancer.2020.05.012_bib0510","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1002\/bjs.9872","article-title":"Portal vein embolization and its effect on tumour progression for colorectal cancer liver metastases","volume":"102","author":"Simoneau","year":"2015","journal-title":"Br. J. Surg."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0515","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1097\/00000658-200012000-00006","article-title":"Two-stage hepatectomy: a planned strategy to treat irresectable liver tumors","volume":"232","author":"Adam","year":"2000","journal-title":"Ann. Surg."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0520","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1097\/01.sla.0000145965.86383.89","article-title":"A two-stage hepatectomy procedure combined with portal vein embolization to achieve curative resection for initially unresectable multiple and bilobar colorectal liver metastases","volume":"240","author":"Jaeck","year":"2004","journal-title":"Ann. Surg."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0525","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/bjs.6756","article-title":"Impact of portal vein embolization on long-term survival of patients with primarily unresectable colorectal liver metastases","volume":"97","author":"Wicherts","year":"2010","journal-title":"Br. J. Surg."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0530","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.ejso.2006.10.038","article-title":"Remnant liver regeneration after two-stage hepatectomy for multiple bilobar colorectal metastases","volume":"33","author":"Tanaka","year":"2007","journal-title":"Eur. J. Surg. Oncol."},{"issue":"11","key":"10.1016\/j.semcancer.2020.05.012_bib0535","doi-asserted-by":"crossref","first-page":"3709","DOI":"10.1245\/s10434-016-5264-6","article-title":"Oncological outcomes of major liver resection following portal vein embolization: a systematic review and meta-analysis","volume":"23","author":"Giglio","year":"2016","journal-title":"Ann. Surg. Oncol."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0540","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/bja\/85.1.109","article-title":"The stress response to trauma and surgery","volume":"85","author":"Desborough","year":"2000","journal-title":"Br. J. Anaesth."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0545","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nrclinonc.2014.224","article-title":"Exploiting the critical perioperative period to improve long-term cancer outcomes","volume":"12","author":"Horowitz","year":"2015","journal-title":"Nat Rev Clin Oncol."},{"key":"10.1016\/j.semcancer.2020.05.012_bib0550","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1016\/j.bbi.2012.03.006","article-title":"Surgery and stress promote cancer metastasis: new outlooks on perioperative mediating mechanisms and immune involvement","volume":"30","author":"Neeman","year":"2013","journal-title":"Brain Behav. Immun."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0555","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/ssu.1051","article-title":"Surgical strategies and minimal residual disease detection","volume":"20","author":"Weitz","year":"2001","journal-title":"Semin. Surg. Oncol."},{"issue":"18","key":"10.1016\/j.semcancer.2020.05.012_bib0560","doi-asserted-by":"crossref","first-page":"4895","DOI":"10.1158\/1078-0432.CCR-12-1087","article-title":"A new approach to reducing postsurgical cancer recurrence: perioperative targeting of catecholamines and prostaglandins","volume":"18","author":"Neeman","year":"2012","journal-title":"Clin Cancer Res."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0565","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.bbi.2008.10.005","article-title":"Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: implications for stress-related enhancement of tumor progression","volume":"23","author":"Yang","year":"2009","journal-title":"Brain Behav. Immun."},{"issue":"18","key":"10.1016\/j.semcancer.2020.05.012_bib0570","doi-asserted-by":"crossref","first-page":"13802","DOI":"10.1074\/jbc.275.18.13802","article-title":"Norepinephrine induces vascular endothelial growth factor gene expression in brown adipocytes through a beta -adrenoreceptor\/cAMP\/protein kinase A pathway involving Src but independently of Erk1\/2","volume":"275","author":"Fredriksson","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.semcancer.2020.05.012_bib0575","first-page":"4514","article-title":"Stress-related mediators stimulate vascular endothelial growth factor secretion by two ovarian cancer cell lines","volume":"9","author":"Lutgendorf","year":"2003","journal-title":"Clin. Cancer Res."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0580","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/0092-8674(94)90200-3","article-title":"Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma","volume":"79","author":"O\u2019Reilly","year":"1994","journal-title":"Cell."},{"key":"10.1016\/j.semcancer.2020.05.012_bib0585","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bbi.2016.05.017","article-title":"Reducing liver metastases of colon cancer in the context of extensive and minor surgeries through \u03b2-adrenoceptors blockade and COX2 inhibition","volume":"58","author":"Sorski","year":"2016","journal-title":"Brain Behav. Immun."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0590","doi-asserted-by":"crossref","first-page":"2449","DOI":"10.4049\/jimmunol.0903301","article-title":"Improving survival rates in two models of spontaneous postoperative metastasis in mice by combined administration of a beta-adrenergic antagonist and a cyclooxygenase-2 inhibitor","volume":"184","author":"Glasner","year":"2010","journal-title":"J Immunol."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0595","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019246","article-title":"Do stress responses promote leukemia progression? An animal study suggesting a role for epinephrine and prostaglandin-E2 through reduced NK activity","volume":"6","author":"Inbar","year":"2011","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0600","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/BF01655244","article-title":"Preoperative portal vein embolization for hepatocellular carcinoma","volume":"10","author":"Kinoshita","year":"1986","journal-title":"World J. Surg."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0605","first-page":"521","article-title":"Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report","volume":"107","author":"Makuuchi","year":"1990","journal-title":"Surgery."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0610","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.surg.2017.12.027","article-title":"Natural history of portal vein embolization before liver resection: a 23-year analysis of intention-to-treat results","volume":"163","author":"Alvarez","year":"2018","journal-title":"Surgery."},{"issue":"11","key":"10.1016\/j.semcancer.2020.05.012_bib0615","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1200\/JCO.2007.13.7679","article-title":"Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer","volume":"26","author":"Gruenberger","year":"2008","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.semcancer.2020.05.012_bib0620","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.amsu.2017.12.003","article-title":"Impact of liver volume and liver function on posthepatectomy liver failure after portal vein embolization- A multivariable cohort analysis","volume":"25","author":"Alizai","year":"2018","journal-title":"Ann Med Surg."},{"issue":"7","key":"10.1016\/j.semcancer.2020.05.012_bib0625","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1080\/02841850701424514","article-title":"Acceleration of primary liver tumor growth rate in embolized hepatic lobe after portal vein embolization","volume":"48","author":"Hayashi","year":"2007","journal-title":"Acta Radiol."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0630","first-page":"98","article-title":"Preoperative right portal vein embolization in patients with metastatic liver disease. Metastatic liver volumes after RPVE","volume":"44","author":"Barbaro","year":"2003","journal-title":"Acta Radiol."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0635","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1046\/j.1365-2168.1999.01154.x","article-title":"During liver regeneration following right portal embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma","volume":"86","author":"Elias","year":"1999","journal-title":"Br. J. Surg."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0640","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1053\/jhep.2001.26513","article-title":"Proliferative activity of intrahepatic colorectal metastases after preoperative hemihepatic portal vein embolization","volume":"34","author":"Kokudo","year":"2001","journal-title":"Hepatology."},{"issue":"2","key":"10.1016\/j.semcancer.2020.05.012_bib0645","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1245\/s10434-008-0222-6","article-title":"Induction of tumor growth after preoperative portal vein embolization: is it a real problem?","volume":"16","author":"de Graaf","year":"2009","journal-title":"Ann. Surg. Oncol."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0650","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.jamcollsurg.2013.03.004","volume":"217","author":"Shindoh","year":"2013","journal-title":"J. Am. Coll. Surg."},{"key":"10.1016\/j.semcancer.2020.05.012_bib0655","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ijsu.2018.11.029","article-title":"Portal vein embolization does not affect the long-term survival and risk of cancer recurrence among colorectal liver metastases patients: a prospective cohort study","volume":"61","author":"Collin","year":"2019","journal-title":"Int. J. Surg."},{"issue":"12","key":"10.1016\/j.semcancer.2020.05.012_bib0660","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1001\/jamasurg.2013.2126","article-title":"Chemotherapy after portal vein embolization to protect against tumor growth during liver hypertrophy before hepatectomy","volume":"148","author":"Fischer","year":"2013","journal-title":"JAMA Surg."},{"issue":"10","key":"10.1016\/j.semcancer.2020.05.012_bib0665","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1245\/s10434-008-0035-7","article-title":"Chemotherapy with bevacizumab does not affect liver regeneration after portal vein embolization in the treatment of colorectal liver metastases","volume":"15","author":"Zorzi","year":"2008","journal-title":"Ann. Surg. Oncol."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0670","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jvir.2018.10.014","article-title":"Future liver remnant hypertrophy after portal vein embolization is inversely correlated with intrahepatic tumor burden","volume":"30","author":"Takahashi","year":"2019","journal-title":"J. Vasc. Interv. Radiol."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0675","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ejso.2017.09.017","article-title":"Does portal vein embolization prior to liver resection influence the oncological outcomes - A propensity score matched comparison","volume":"44","author":"Huiskens","year":"2018","journal-title":"Eur. J. Surg. Oncol."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0680","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1159\/000176063","article-title":"Prospective evaluation of two-stage hepatectomy combined with selective portal vein embolisation and systemic chemotherapy for patients with unresectable bilobar colorectal liver metastases","volume":"25","author":"Pamecha","year":"2008","journal-title":"Dig. Surg."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0685","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/SLA.0b013e31815aa2c2","article-title":"Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients","volume":"247","author":"Rees","year":"2008","journal-title":"Ann. Surg."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0690","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/s11605-018-3890-y","article-title":"Surgical resection for recurrence after two-stage hepatectomy for colorectal liver metastases is feasible, is safe, and improves survival","volume":"23","author":"Lillemoe","year":"2019","journal-title":"J. Gastrointest. Surg."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0695","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1097\/SLA.0000000000002511","article-title":"ALPPS improves resectability compared with conventional two-stage hepatectomy in patients with advanced colorectal liver metastasis: results from a scandinavian multicenter randomized controlled trial (LIGRO trial)","volume":"267","author":"Sandstr\u00f6m","year":"2018","journal-title":"Ann. Surg."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0700","doi-asserted-by":"crossref","DOI":"10.1016\/j.surg.2018.02.026","article-title":"Indicating ALPPS for colorectal liver metastases: a critical analysis of patients in the international ALPPS registry","volume":"164","author":"Schnitzbauer","year":"2018","journal-title":"Surgery."},{"issue":"3","key":"10.1016\/j.semcancer.2020.05.012_bib0705","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/SLA.0b013e31824856f5","article-title":"Right portal vein ligation combined with in situ splitting induces rapid left lateral liver lobe hypertrophy enabling 2-staged extended right hepatic resection in small-for-size settings","volume":"255","author":"Schnitzbauer","year":"2012","journal-title":"Ann. Surg."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0710","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1097\/SLA.0000000000000949","article-title":"ALPPS: from human to mice highlighting accelerated and novel mechanisms of liver regeneration","volume":"260","author":"Schlegel","year":"2014","journal-title":"Ann. Surg."},{"issue":"11","key":"10.1016\/j.semcancer.2020.05.012_bib0715","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1007\/s11605-017-3523-x","article-title":"Remnant liver tumor growth activity during treatment associating liver partition and portal vein occlusion for staged hepatectomy (ALPPS)","volume":"21","author":"Kikuchi","year":"2017","journal-title":"J. Gastrointest. Surg."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0720","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1007\/s00268-013-2401-2","article-title":"ALPPS for patients with colorectal liver metastases: effective liver hypertrophy, but early tumor recurrence","volume":"38","author":"Oldhafer","year":"2014","journal-title":"World J. Surg."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0725","first-page":"65","article-title":"Metastatic breast cancer presenting as acute liver failure","volume":"7","author":"Nazario","year":"2011","journal-title":"Gastroenterol Hepatol."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0730","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S0168-8278(02)00219-2","article-title":"Acute liver failure caused by diffuse hepatic melanoma infiltration","volume":"37","author":"Montero","year":"2002","journal-title":"J. Hepatol."},{"issue":"10","key":"10.1016\/j.semcancer.2020.05.012_bib0735","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1001\/archsurg.137.10.1187","article-title":"Liver resection for multiple colorectal metastases: influence of parenchymal involvement and total tumor volume, vs number or location, on long-term survival","volume":"137","author":"Ercolani","year":"2002","journal-title":"Arch Surg."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0740","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0925-4773(02)00338-6","article-title":"The role of hepatocytes and oval cells in liver regeneration and repopulation","volume":"120","author":"Fausto","year":"2003","journal-title":"Mech. Dev."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0745","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.stem.2014.04.010","article-title":"Stem\/progenitor cells in liver development, homeostasis, regeneration, and reprogramming","volume":"14","author":"Miyajima","year":"2014","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0750","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/hep.30150","article-title":"Ductular reaction in liver diseases: pathological mechanisms and translational significances","volume":"69","author":"Sato","year":"2019","journal-title":"Hepatology."},{"issue":"5","key":"10.1016\/j.semcancer.2020.05.012_bib0755","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1365-2559.2006.02372.x","article-title":"Oval cells in hepatitis B virus-positive and hepatitis C virus-positive liver cirrhosis: histological and ultrastructural study","volume":"48","author":"Sun","year":"2006","journal-title":"Histopathology"},{"issue":"12","key":"10.1016\/j.semcancer.2020.05.012_bib0760","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1002\/lt.24007","article-title":"Analysis of the intrahepatic ductular reaction and progenitor cell responses in hepatitis C virus recurrence after liver transplantation","volume":"20","author":"Prakoso","year":"2014","journal-title":"Liver Transpl."},{"issue":"4","key":"10.1016\/j.semcancer.2020.05.012_bib0765","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1002\/hep.26937","article-title":"The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease","volume":"59","author":"Gadd","year":"2014","journal-title":"Hepatology."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0770","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1002\/hep.25614","article-title":"Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis","volume":"55","author":"Sancho-Bru","year":"2012","journal-title":"Hepatology."},{"issue":"12","key":"10.1016\/j.semcancer.2020.05.012_bib0775","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1136\/gutjnl-2014-308410","article-title":"Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis","volume":"64","author":"Dubuquoy","year":"2015","journal-title":"Gut."},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0780","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1111\/ctr.12740","article-title":"Increased hepatic progenitor cell response and ductular reaction in patients with severe recurrent HCV post-liver transplantation","volume":"30","author":"Sclair","year":"2016","journal-title":"Clin Transplant."},{"issue":"1","key":"10.1016\/j.semcancer.2020.05.012_bib0785","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/1471-2407-14-65","article-title":"Peritumoral ductular reaction: a poor postoperative prognostic factor for hepatocellular carcinoma","volume":"14","author":"Xu","year":"2014","journal-title":"BMC Cancer. BioMed Central"},{"issue":"6","key":"10.1016\/j.semcancer.2020.05.012_bib0790","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.jhep.2004.08.017","article-title":"Progenitor cell expansion: an important source of hepatocyte regeneration in chronic hepatitis","volume":"41","author":"Eleazar","year":"2004","journal-title":"J. Hepatol."}],"container-title":["Seminars in Cancer Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044579X20301085?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1044579X20301085?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T23:45:50Z","timestamp":1760917550000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1044579X20301085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":158,"alternative-id":["S1044579X20301085"],"URL":"https:\/\/doi.org\/10.1016\/j.semcancer.2020.05.012","relation":{},"ISSN":["1044-579X"],"issn-type":[{"value":"1044-579X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Liver regeneration and liver metastasis","name":"articletitle","label":"Article Title"},{"value":"Seminars in Cancer Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semcancer.2020.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}