{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:08:05Z","timestamp":1791468485793,"version":"4.3.4"},"reference-count":107,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Cell & Developmental Biology"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.semcdb.2011.07.009","type":"journal-article","created":{"date-parts":[[2011,7,25]],"date-time":"2011-07-25T20:01:40Z","timestamp":1311624100000},"page":"645-652","source":"Crossref","is-referenced-by-count":319,"title":["The role of iodine in human growth and development"],"prefix":"10.1016","volume":"22","author":[{"given":"Michael B.","family":"Zimmermann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semcdb.2011.07.009_bib0005","first-page":"128","article-title":"The prevention of simple goiter in man. A survey of the incidence and types of thyroid enlargements in the schoolgirls of Akron (Ohio), from the 5th to the 12th grades, inclusive\u2014the plan of prevention proposed, 1917","volume":"115","author":"Marine","year":"1990","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0010","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1016\/S0140-6736(83)90636-0","article-title":"Iodine deficiency disorders (IDD) and their eradication","volume":"2","author":"Hetzel","year":"1983","journal-title":"Lancet"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0015","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/S0140-6736(08)61005-3","article-title":"Iodine-deficiency disorders","volume":"372","author":"Zimmermann","year":"2008","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.semcdb.2011.07.009_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.beem.2009.08.005","article-title":"Epidemiology of iodine deficiency: salt iodisation and iodine status","volume":"24","author":"Andersson","year":"2010","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0025","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1177\/156482650802900305","article-title":"Iodine deficiency in 2007: global progress since 2003","volume":"29","author":"de Benoist","year":"2008","journal-title":"Food Nutr Bull"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0030","series-title":"Iodine. Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium and zinc","author":"Institute of Medicine AoS","year":"2001"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0035","series-title":"Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers","author":"World Health Organization UNCsF, International Council for Control of Iodine Deficiency Disorders","year":"2007"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0040","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1079\/PNS19670013","article-title":"Some aspects of the absorption and concentration of iodide by the alimentary tract in man","volume":"26","author":"Alexander","year":"1967","journal-title":"Proc Nutr Soc"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0045","first-page":"66","article-title":"Urinary excretion of iodide and fluoride from supplemented food grade salt","volume":"62","author":"Nath","year":"1992","journal-title":"Int J Vitam Nutr Res"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0050","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1210\/jcem-29-5-721","article-title":"Thyroid iodine content and turnover in euthyroid subjects\u2014validity of estimation of thyroid iodine accumulation from short-term clearance studies","volume":"29","author":"Fisher","year":"1969","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0055","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1210\/jcem-26-2-149","article-title":"Kinetic analysis of iodine metabolism","volume":"26","author":"Degroot","year":"1966","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0060","series-title":"The adaptation of man to iodine deficiency","author":"Stanbury","year":"1954"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0065","series-title":"Werner and Ingbar's the thyroid: a fundamental and clinical text","first-page":"295","article-title":"Iodine deficiency","author":"Delange","year":"2000"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0070","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1210\/er.18.3.404","article-title":"The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology","volume":"18","author":"Glinoer","year":"1997","journal-title":"Endocr Rev"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0075","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0083-6729(05)71004-9","article-title":"Thyroid hormones and brain development","volume":"71","author":"Bernal","year":"2005","journal-title":"Vitam Horm"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0080","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S1043-2760(02)00043-7","article-title":"Thyroid hormone receptors: lessons from knockout and knock-in mutant mice","volume":"14","author":"Flamant","year":"2003","journal-title":"Trends Endocrin Met"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0085","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.tem.2005.09.007","article-title":"Membrane receptors mediating thyroid hormone action","volume":"16","author":"Davis","year":"2005","journal-title":"Trends Endocrin Met"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0090","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1111\/j.1365-2826.2004.01243.x","article-title":"Timing of thyroid hormone action in the developing brain: clinical observations and experimental findings","volume":"16","author":"Zoeller","year":"2004","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0095","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/S0166-2236(96)10072-2","article-title":"GAP-43: an intrinsic determinant of neuronal development and plasticity","volume":"20","author":"Benowitz","year":"1997","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0100","doi-asserted-by":"crossref","first-page":"10660","DOI":"10.1523\/JNEUROSCI.2213-04.2004","article-title":"Neurogranin\/RC3 enhances long-term potentiation and learning by promoting calcium-mediated signaling","volume":"24","author":"Huang","year":"2004","journal-title":"J Neurosci"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0105","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1126\/science.1321493","article-title":"Impaired spatial-learning in alpha-calcium-calmodulin kinase-II mutant mice","volume":"257","author":"Silva","year":"1992","journal-title":"Science"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0110","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.neuron.2004.08.028","article-title":"Hippocampus: cognitive processes and neural representations that underlie declarative memory","volume":"44","author":"Eichenbaum","year":"2004","journal-title":"Neuron"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0115","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/j.1365-2826.2009.01943.x","article-title":"Developmental iodine deficiency and hypothyroidism impair neural development, up-regulate caveolin-1 and down-regulate synaptophysin in rat hippocampus","volume":"22","author":"Gong","year":"2010","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0120","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.beem.2004.03.012","article-title":"Maternal thyroid hormones early in pregnancy and fetal brain development","volume":"18","author":"de Escobar","year":"2004","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0125","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1210\/endo-114-2-677","article-title":"Ontogenesis of the nuclear 3,5,3\u2032-triiodothyronine receptor in the human fetal brain","volume":"114","author":"Bernal","year":"1984","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0130","first-page":"115","article-title":"Changes of event related potential and cognitive processes in patients with subclinical hypothyroidism after thyroxine treatment","volume":"36","author":"Jensovsky","year":"2002","journal-title":"Endocr Regul"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0135","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.mcn.2005.03.010","article-title":"Thyroid hormone regulates hippocampal neurogenesis in the adult rat brain","volume":"29","author":"Desouza","year":"2005","journal-title":"Mol Cell Neurosci"},{"issue":"February (2S Suppl.)","key":"10.1016\/j.semcdb.2011.07.009_bib0140","doi-asserted-by":"crossref","first-page":"493S","DOI":"10.1093\/jn\/130.2.493S","article-title":"Iodine and neuropsychological development","volume":"130","author":"Hetzel","year":"2000","journal-title":"J Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0145","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1056\/NEJM198907063210103","article-title":"Maternal fetal transfer of thyroxine in congenital hypothyroidism due to a total organification defect or thyroid agenesis","volume":"321","author":"Vulsma","year":"1989","journal-title":"New Engl J Med"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0150","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/S0140-6736(01)62987-8","article-title":"Observations on endemic cretinism in the Chitral and Gilgit valleys","volume":"2","author":"McCarrison","year":"1908","journal-title":"Lancet"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0155","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.beem.2009.08.014","article-title":"Cretinism revisited","volume":"24","author":"Chen","year":"2010","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0160","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/S0140-6736(71)91040-3","article-title":"Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy","volume":"1","author":"Pharoah","year":"1971","journal-title":"Lancet"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0165","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1093\/ije\/16.1.68","article-title":"A controlled trial of iodinated oil for the prevention of endemic cretinism: a long-term follow-up","volume":"16","author":"Pharoah","year":"1987","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0170","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1136\/adc.66.1.145","article-title":"Effects of maternal iodine supplementation during pregnancy","volume":"66","author":"Pharoah","year":"1991","journal-title":"Arch Dis Child"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0175","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1210\/jcem-47-2-354","article-title":"Fetal hypo-thyroidism and maternal thyroid status in severe endemic goiter","volume":"47","author":"Thilly","year":"1978","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0180","series-title":"The damaged brain of iodine deficiency cognitive, behavioral, neuromotor, educative aspects","article-title":"Maternal, fetal and juvenile hypothyroidism, birthweight and infant mortality in the etiopathogenesis of the IDD spectrum in Zaire and Malawi","author":"Moreno-Reyes","year":"1994"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0185","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1056\/NEJM199412293312603","article-title":"Timing of vulnerability of the brain to iodine deficiency in endemic cretinism","volume":"331","author":"Cao","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0190","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1017\/S0012162201001712","article-title":"Effects of iodine supplementation during pregnancy on child growth and development at school age","volume":"44","author":"O\u2019Donnell","year":"2002","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0195","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1056\/NEJM199908193410801","article-title":"Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child","volume":"341","author":"Haddow","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0200","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1365-2265.1999.00639.x","article-title":"Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy","volume":"50","author":"Pop","year":"1999","journal-title":"Clin Endocrinol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0205","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1210\/jc.2008-0936","article-title":"Neonatal thyroxine, maternal thyroid function, and child cognition","volume":"94","author":"Oken","year":"2009","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0210","doi-asserted-by":"crossref","first-page":"668S","DOI":"10.3945\/ajcn.2008.26811C","article-title":"Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review","volume":"89","author":"Zimmermann","year":"2009","journal-title":"Am J Clin Nutr"},{"issue":"Suppl. 3","key":"10.1016\/j.semcdb.2011.07.009_bib0215","doi-asserted-by":"crossref","first-page":"U25","DOI":"10.1530\/eje.0.151U025","article-title":"Role of thyroid hormone during early brain development","volume":"151","author":"Morreale de Escobar","year":"2004","journal-title":"Eur J Endocrinol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0220","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1530\/eje.0.1300547","article-title":"Prevention of iodine deficiency disorders by oral administration of lipiodol during pregnancy","volume":"130","author":"Chaouki","year":"1994","journal-title":"Eur J Endocrinol"},{"issue":"3","key":"10.1016\/j.semcdb.2011.07.009_bib0225","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1530\/EJE-08-0716","article-title":"Iodine levels and thyroid hormones in healthy pregnant women and birth weight of their offspring","volume":"160","author":"Alvarez-Pedrerol","year":"2009","journal-title":"Eur J Endocrinol"},{"issue":"5","key":"10.1016\/j.semcdb.2011.07.009_bib0230","first-page":"535","article-title":"Effect of environmental iodine deficiency (EID) on foetal growth in Nigeria","volume":"124","author":"Das","year":"2006","journal-title":"Indian J Med Res"},{"issue":"3","key":"10.1016\/j.semcdb.2011.07.009_bib0235","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1177\/156482650202300309","article-title":"Iodine fortification is related to increased weight-for-age and birthweight in children in Asia","volume":"23","author":"Mason","year":"2002","journal-title":"Food Nutr Bull"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0240","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0140-6736(96)12365-5","article-title":"Effect on infant mortality of iodination of irrigation water in a severely iodine-deficient area of China","volume":"350","author":"DeLong","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0245","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1210\/jcem-47-2-354","article-title":"Fetal hypothyroidism and maternal thyroid status in severe endemic goiter","volume":"47","author":"Thilly","year":"1978","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0250","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1093\/jn\/127.4.574","article-title":"Infant survival is improved by oral iodine supplementation","volume":"127","author":"Cobra","year":"1997","journal-title":"J Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0255","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1093\/ajcn\/87.2.438","article-title":"Child malnutrition and mortality among families not utilizing adequately iodized salt in Indonesia","volume":"87","author":"Semba","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0260","first-page":"199","article-title":"Physical, neuromotor and intellectual impairment in non-cretinous schoolchildren with iodine deficiency","volume":"65","author":"Azizi","year":"1995","journal-title":"Int J Vitam Nutr Res"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0265","doi-asserted-by":"crossref","first-page":"676","DOI":"10.5694\/j.1326-5377.1989.tb136760.x","article-title":"Iodine deficiency impairs intellectual and neuromotor development in apparently-normal persons. A study of rural inhabitants of north-central China","volume":"150","author":"Boyages","year":"1989","journal-title":"Med J Aust"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0270","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1093\/jn\/133.10.3162","article-title":"Subclinical prenatal iodine deficiency negatively affects infant development in Northern China","volume":"133","author":"Choudhury","year":"2003","journal-title":"J Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0275","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/BF03350696","article-title":"Neuropsychological assessment in schoolchildren from an area of moderate iodine deficiency","volume":"13","author":"Fenzi","year":"1990","journal-title":"J Endocrinol Invest"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0280","first-page":"1518","article-title":"Effect of different iodine intake on schoolchildren's thyroid diseases and intelligence in rural areas","volume":"117","author":"Gao","year":"2004","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0285","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1093\/jn\/129.5.980","article-title":"Biochemical hypothyroidism secondary to iodine deficiency is associated with poor school achievement and cognition in Bangladeshi children","volume":"129","author":"Huda","year":"1999","journal-title":"J Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0290","first-page":"95","article-title":"The influence of iodine deficiency on the cognitive performance of school children in Saki, south-west Nigeria","volume":"27","author":"Ojule","year":"1998","journal-title":"Afr J Med Sci"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0295","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1210\/jcem-70-2-379","article-title":"Defective neuromotor and cognitive-ability in iodine-deficient schoolchildren of an endemic goiter region in Sicily","volume":"70","author":"Vermiglio","year":"1990","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0300","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.1210\/jc.2003-031652","article-title":"Intelligence quotient and iodine intake: a cross-sectional study in children","volume":"89","author":"Santiago-Fernandez","year":"2004","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0305","doi-asserted-by":"crossref","first-page":"6054","DOI":"10.1210\/jc.2004-0571","article-title":"Attention deficit and hyperactivity disorders in the offspring of mothers exposed to mild\u2013moderate iodine deficiency: a possible novel iodine deficiency disorder in developed countries","volume":"89","author":"Vermiglio","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0310","doi-asserted-by":"crossref","first-page":"80","DOI":"10.2307\/1131438","article-title":"Stability of intelligence from preschool to adolescence\u2014the influence of social and family risk-factors","volume":"64","author":"Sameroff","year":"1993","journal-title":"Child Dev"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0315","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/ajcn\/35.1.127","article-title":"The effects of oral iodized oil on intelligence, thyroid status, and somatic growth in school-age children from an area of endemic goiter","volume":"35","author":"Bautista","year":"1982","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0320","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1093\/jn\/131.1.72","article-title":"Cognitive and motor functions of iodine-deficient but euthyroid children in Bangladesh do not benefit from iodized poppy seed oil (Lipiodol)","volume":"131","author":"Huda","year":"2001","journal-title":"J Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0325","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1046\/j.1440-6047.2000.00160.x","article-title":"Effect of iodized oil supplementation on thyroid hormone levels and mental performance among Orang Asli schoolchildren and pregnant mothers in an endemic goitre area in Peninsular Malaysia","volume":"9","author":"Isa","year":"2000","journal-title":"Asia Pac J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0330","unstructured":"Shrestha R. Effect of iodine and iron supplementation on physical, psychomotor and mental development in primary school children in Malawi [doctoral thesis]. Wageningen: Wageningen Agricultural University; 1994."},{"key":"10.1016\/j.semcdb.2011.07.009_bib0335","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1093\/ajcn\/83.1.108","article-title":"Iodine supplementation improves cognition in iodine-deficient schoolchildren in Albania: a randomized, controlled, double-blind study","volume":"83","author":"Zimmermann","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0340","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.3945\/ajcn.2009.28145","article-title":"Iodine supplementation improves cognition in mildly iodine-deficient children","volume":"90","author":"Gordon","year":"2009","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"10.1016\/j.semcdb.2011.07.009_bib0345","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1677\/JME-09-0067","article-title":"Cellular approaches to central nervous system remyelination stimulation: thyroid hormone to promote myelin repair via endogenous stem and precursor cells","volume":"44","author":"Calz\u00e0","year":"2010","journal-title":"J Mol Endocrinol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0350","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1146\/annurev.ph.49.030187.001541","article-title":"Thyroid hormones and brain development","volume":"49","author":"Dussault","year":"1987","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0355","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1007\/s00394-008-3002-y","article-title":"Nutrition and cognition: assessing cognitive abilities in children and young people","volume":"47","author":"Isaacs","year":"2008","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0360","series-title":"The damaged brain of iodine deficiency cognitive, behavioral, neuromotor, educative aspects","article-title":"A metaanalysis of research on iodine and its relationship to cognitive development","author":"Bleichrodt","year":"1994"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0365","first-page":"32","article-title":"The effects of iodine on intelligence in children: a meta-analysis of studies conducted in China","volume":"14","author":"Qian","year":"2005","journal-title":"Asia Pac J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0370","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1093\/ajcn\/26.12.1360","article-title":"Endemic goiter in Greece: nutritional status, growth, and skeletal development of goitrous and non goitrous populations","volume":"26","author":"Koutras","year":"1973","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0375","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1093\/ajcn\/30.2.275","article-title":"Lack of correlation between thyroid size and body growth in an area of endemic goiter","volume":"30","author":"Bautista","year":"1977","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0380","first-page":"852","article-title":"Thyroid function and pubertal development in malnutrition","volume":"23","author":"Ali","year":"1994","journal-title":"Ann Acad Med Singapore"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0385","first-page":"10","article-title":"A study of spectrum of iodine deficiency disorders in rural area of Uttar Pradesh","volume":"40","author":"Lal","year":"1996","journal-title":"Indian J Publ Health"},{"issue":"Suppl. 1","key":"10.1016\/j.semcdb.2011.07.009_bib0390","first-page":"S90","article-title":"Onset and evolution of stunting in infants and children. Examples from the Human Nutrition Collaborative Research Support Program. Kenya and Egypt studies","volume":"48","author":"Neumann","year":"1994","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0395","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/sj.ejcn.1602361","article-title":"Risk of zinc, iodine and other micronutrient deficiencies among school children in North East Thailand","volume":"60","author":"Thurlow","year":"2006","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0400","first-page":"198","article-title":"Effect of environmental supplementation of iodine on infant mortality and growth in children in Xinjiang, China","volume":"23","author":"Ren","year":"2002","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0405","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1093\/ajcn\/78.1.137","article-title":"Selenium and iodine supplementation of rural Tibetan children affected by Kashin\u2013Beck osteoarthropathy","volume":"78","author":"Moreno-Reyes","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0410","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1093\/ajcn\/74.5.657","article-title":"Multiple micronutrient supplementation increases the growth of Mexican infants","volume":"74","author":"Rivera","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0415","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/ajcn\/69.3.497","article-title":"Effect of iron-, iodine-, and beta-carotene-fortified biscuits on the micronutrient status of primary school children: a randomized controlled trial","volume":"69","author":"van Stuijvenberg","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0420","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1073\/pnas.75.1.45","article-title":"Thyroid and glucocorticoid hormones synergistically control growth-hormone messenger-Rna in cultured Gh1 cells","volume":"75","author":"Shapiro","year":"1978","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0425","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1203\/00006450-200208000-00003","article-title":"Interactions between GH, IGF-I, glucocorticoids, and thyroid hormones during skeletal growth","volume":"52","author":"Robson","year":"2002","journal-title":"Pediatr Res"},{"issue":"6","key":"10.1016\/j.semcdb.2011.07.009_bib0430","doi-asserted-by":"crossref","first-page":"E934","DOI":"10.1210\/jc.2010-2814","article-title":"Fetal thyroid hormone level at birth is associated with fetal growth","volume":"96","author":"Shields","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0435","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1210\/en.130.3.1483","article-title":"Regulation of insulin-like growth factor-binding protein expression by thyroid-hormone in rat Gh3 pituitary-tumor cells","volume":"130","author":"Ceda","year":"1992","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0440","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1210\/endo-128-2-937","article-title":"Growth-hormone regulation in primary fetal and neonatal rat pituitary cell-cultures\u2014the role of thyroid-hormone","volume":"128","author":"Ezzat","year":"1991","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0445","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.1210\/endo-124-5-2277","article-title":"The effect of altered thyroid status on pituitary-hormone messenger ribonucleic-acid concentrations in the rat","volume":"124","author":"Samuels","year":"1989","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0450","doi-asserted-by":"crossref","first-page":"5018","DOI":"10.1016\/S0021-9258(19)89208-6","article-title":"Thyroid hormone regulation of the transfected rat growth hormone promoter","volume":"261","author":"Crew","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0455","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1210\/endo-126-1-325","article-title":"Alterations of human growth-hormone binding by rat-liver membranes during hypothyroidism and hyperthyroidism","volume":"126","author":"Hochberg","year":"1990","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0460","first-page":"S150","article-title":"Hormonal-regulation of longitudinal bone-growth","volume":"48","author":"Nilsson","year":"1994","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0465","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1111\/j.1365-2362.1995.tb01729.x","article-title":"Effect of thyroid replacement therapy on the stature of Colombian children with minimal thyroid dysfunction","volume":"25","author":"Hernandez-Cassis","year":"1995","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0470","first-page":"3","article-title":"Insulin-like growth factors and their binding proteins: biological actions","volume":"16","author":"Jones","year":"1995","journal-title":"Endocr Rev"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0475","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1385\/ENDO:19:3:249","article-title":"A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived IGF-I","volume":"19","author":"Sjogren","year":"2002","journal-title":"Endocrine"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0480","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1159\/000023315","article-title":"Insulin-like growth factor binding proteins: new proteins, new functions","volume":"51","author":"Ferry","year":"1999","journal-title":"Horm Res"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0485","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1210\/endo-104-4-1107","article-title":"Effect of hypo-thyroidism on growth, serum growth-hormone, the growth hormone-dependent somatomedin, insulin-like growth-factor, and its carrier protein in rats","volume":"104","author":"Burstein","year":"1979","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0490","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.1365-2826.1989.tb00100.x","article-title":"Triiodothyronine regulates insulin-like growth factor-I binding to cultured rat pituitary-cells","volume":"1","author":"Geary","year":"1989","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0495","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1210\/jc.76.4.950","article-title":"Effects of hypothyroidism and hyperthyroidism on insulin-like growth-factors (IGFs) and growth hormone-binding and IGF-binding proteins","volume":"76","author":"Miell","year":"1993","journal-title":"J Clin Endocr Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0500","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1210\/jc.76.5.1199","article-title":"Thyroxine withdrawal is accompanied by decreased circulating levels of insulin-like growth factor binding protein-1 in thyroidectomized patients","volume":"76","author":"Angerva","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0505","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1210\/en.132.2.781","article-title":"Mechanisms of thyroid hormone action on the insulin-like growth factor system: all thyroid hormone effects are not growth hormone mediated","volume":"132","author":"Nanto-Salonen","year":"1993","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0510","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1089\/105072501753271734","article-title":"Serum insulin-like growth factor type 1, insulin-like growth factor-binding protein-1, and insulin-like growth factor-binding protein-3 concentrations in patients with thyroid dysfunction","volume":"11","author":"Iglesias","year":"2001","journal-title":"Thyroid"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0515","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1046\/j.1365-2265.1996.00785.x","article-title":"Effects of iodine deficiency on insulin-like growth factor-I, insulin-like growth factor-binding protein-3 levels and height attainment in malnourished children","volume":"45","author":"Wan Nazaimoon","year":"1996","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0520","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1385\/BTER:90:1-3:25","article-title":"Insulin-like growth factor-I and insulin-like growth factor binding protein-3 levels of children living in an iodine- and selenium-deficient endemic goiter area","volume":"90","author":"Aydin","year":"2002","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0525","first-page":"215","article-title":"Serum insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 levels in severe iodine deficiency","volume":"44","author":"Alikasifoglu","year":"2002","journal-title":"Turk J Pediatr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0530","first-page":"303","article-title":"Influence of iodine supplementation on serum insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) levels in severe iodine deficiency","volume":"46","author":"Ozon","year":"2004","journal-title":"Turk J Pediatr"},{"key":"10.1016\/j.semcdb.2011.07.009_bib0535","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1210\/jc.2006-1901","article-title":"Treatment of iodine deficiency in school-age children increases insulin-like growth factor (IGF)-I and IGF binding protein-3 concentrations and improves somatic growth","volume":"92","author":"Zimmermann","year":"2007","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Seminars in Cell & Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952111000954?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952111000954?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,28]],"date-time":"2021-11-28T18:44:45Z","timestamp":1638125085000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1084952111000954"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":107,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S1084952111000954"],"URL":"https:\/\/doi.org\/10.1016\/j.semcdb.2011.07.009","relation":{},"ISSN":["1084-9521"],"issn-type":[{"value":"1084-9521","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8]]}}}