{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:15:27Z","timestamp":1790399727487,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Cell & Developmental Biology"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.semcdb.2012.10.003","type":"journal-article","created":{"date-parts":[[2012,10,18]],"date-time":"2012-10-18T01:06:16Z","timestamp":1350522376000},"page":"3-10","source":"Crossref","is-referenced-by-count":33,"title":["Primary cilium-dependent sensing of urinary flow and paracrine purinergic signaling"],"prefix":"10.1016","volume":"24","author":[{"given":"Helle A.","family":"Praetorius","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Leipziger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semcdb.2012.10.003_bib0005","doi-asserted-by":"crossref","first-page":"F1287","DOI":"10.1152\/ajprenal.00736.2009","article-title":"Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells","volume":"298","author":"Wenger","year":"2010","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0010","doi-asserted-by":"crossref","first-page":"R1153","DOI":"10.1152\/ajpregu.00402.2005","article-title":"Renal autoregulation: new perspectives regarding the protective and regulatory roles of the underlying mechanisms","volume":"290","author":"Loutzenhiser","year":"2006","journal-title":"American Journal of Physiology: Regulatory, Integrative and Comparative Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0015","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s00424-007-0432-y","article-title":"TRP channels and mechanosensory transduction: insights into the arterial myogenic response","volume":"456","author":"Sharif-Naeini","year":"2008","journal-title":"Pflugers Archives"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0020","article-title":"Renin release: sites, mechanisms, and control","author":"Kurtz","year":"2010","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0025","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1748-1716.1988.tb08395.x","article-title":"Measurements of macula densa cell volume changes in isolated and perfused rabbit cortical thick ascending limb II. Apical and basolateral cell osmotic water permeabilities","volume":"133","author":"Gonzalez","year":"1988","journal-title":"Acta Physiologica Scandinavica"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0030","doi-asserted-by":"crossref","first-page":"R1362","DOI":"10.1152\/ajpregu.00470.2001","article-title":"Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice","volume":"281","author":"Brown","year":"2001","journal-title":"American Journal of Physiology: Regulatory, Integrative and Comparative Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0035","doi-asserted-by":"crossref","first-page":"9983","DOI":"10.1073\/pnas.171317998","article-title":"Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors","volume":"98","author":"Sun","year":"2001","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0040","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1146\/annurev.physiol.65.050102.085738","article-title":"Paracrine factors in tubuloglomerular feedback: adenosine, ATP, and nitric oxide","volume":"65","author":"Schnermann","year":"2003","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0045","doi-asserted-by":"crossref","first-page":"F965","DOI":"10.1152\/ajprenal.00603.2007","article-title":"Tubuloglomerular feedback and renin secretion in NTPDase1\/CD39-deficient mice","volume":"294","author":"Oppermann","year":"2008","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0050","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s11302-009-9147-1","article-title":"ATP, P2 receptors and the renal microcirculation","volume":"5","author":"Inscho","year":"2009","journal-title":"Purinergic Signal"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0055","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1146\/annurev.physiol.67.040403.101353","article-title":"A physiological view of the primary cilium","volume":"67","author":"Praetorius","year":"2005","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0060","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/ki.1988.201","article-title":"Structure and function of the inner medullary collecting duct","volume":"34","author":"Madsen","year":"1988","journal-title":"Kidney International"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0065","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1681\/ASN.2006070700","article-title":"Flow-induced [Ca2+]i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron","volume":"18","author":"Jensen","year":"2007","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0070","first-page":"F132","article-title":"Analysis and modeling of the primary cilium bending response to fluid shear","volume":"272","author":"Schwartz","year":"1997","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0075","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s00232-001-0075-4","article-title":"Bending the MDCK cell primary cilium increases intracellular calcium","volume":"184","author":"Praetorius","year":"2001","journal-title":"Journal of Membrane Biology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0080","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s00232-002-1042-4","article-title":"Removal of the MDCK cell primary cilium abolishes flow sensing","volume":"191","author":"Praetorius","year":"2003","journal-title":"Journal of Membrane Biology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0085","doi-asserted-by":"crossref","first-page":"F437","DOI":"10.1152\/ajprenal.00316.2001","article-title":"Effects of luminal flow and nucleotides on [Ca2+]i in rabbit cortical collecting duct","volume":"283","author":"Woda","year":"2002","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0090","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1242\/dev.127.11.2347","article-title":"The oak ridge polycystic kidney (orpk) disease gene is required for left-right axis determination","volume":"127","author":"Murcia","year":"2000","journal-title":"Development"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0095","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1681\/ASN.2009010014","article-title":"2008 Homer W. Smith Award: insights into the pathogenesis of polycystic kidney disease from gene discovery","volume":"20","author":"Harris","year":"2009","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0100","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/35050128","article-title":"Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents","volume":"408","author":"Hanaoka","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0105","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/ng1076","article-title":"Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells","volume":"33","author":"Nauli","year":"2003","journal-title":"Nature Genetics"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0110","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1152\/physrev.00021.2006","article-title":"Transient receptor potential cation channels in disease","volume":"87","author":"Nilius","year":"2007","journal-title":"Physiological Reviews"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0115","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1038\/ncb2117","article-title":"Primary cilia regulate mTORC1 activity and cell size through Lkb1","volume":"12","author":"Boehlke","year":"2010","journal-title":"Nature Cell Biology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0120","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1007\/s00424-008-0475-8","article-title":"Flow modulates centriole movements in tubular epithelial cells","volume":"456","author":"Kotsis","year":"2008","journal-title":"Pflugers Archives"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0125","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/ng0803-355","article-title":"From cilia to cyst","volume":"34","author":"Watnick","year":"2003","journal-title":"Nature Genetics"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0130","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1083\/jcb.200805124","article-title":"TRPP2 and TRPV4 form a polymodal sensory channel complex","volume":"182","author":"Kottgen","year":"2008","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0135","doi-asserted-by":"crossref","first-page":"F1464","DOI":"10.1152\/ajprenal.90542.2008","article-title":"Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Ca2+ signaling in human ADPKD cyst epithelial cells","volume":"296","author":"Xu","year":"2009","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0140","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1053\/j.gastro.2006.07.003","article-title":"Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling","volume":"131","author":"Masyuk","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0145","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1113\/jphysiol.2004.072306","article-title":"Cell swelling-induced ATP release is tightly dependent on intracellular calcium elevations","volume":"561","author":"Boudreault","year":"2004","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0150","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0165-6147(97)89795-7","article-title":"Release, metabolism and interconversion of adenine and uridine nucleotides: implications for g protein-coupled P2 receptor agonist selectivity trends","volume":"18","author":"Harden","year":"1997","journal-title":"Pharmacological Sciences"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0155","doi-asserted-by":"crossref","first-page":"F133","DOI":"10.1152\/ajprenal.00238.2004","article-title":"Transepithelial pressure pulses induce nucleotide release in polarized MDCK cells","volume":"288","author":"Praetorius","year":"2005","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0160","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/BF00374271","article-title":"The increase in the intracellular Ca2+ concentration induced by mechanical stimulation is propagated via release of pyrophosphorylated nucleotides in mammary epithelial cells","volume":"427","author":"Enomoto","year":"1994","journal-title":"Pfl\u00fcgers Archiv European Journal of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0165","doi-asserted-by":"crossref","first-page":"F978","DOI":"10.1152\/ajprenal.00260.2004","article-title":"Mechanoregulation of intracellular Ca2+ concentration is attenuated in collecting duct of monocilium-impaired orpk mice","volume":"289","author":"Liu","year":"2005","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0170","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1748-1716.2009.02002.x","article-title":"Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells","volume":"197","author":"Praetorius","year":"2009","journal-title":"Acta Physiologiae"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0175","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s11302-007-9072-0","article-title":"Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals","volume":"4","author":"Hovater","year":"2008","journal-title":"Purinergic Signal"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0180","doi-asserted-by":"crossref","first-page":"2779","DOI":"10.1113\/jphysiol.2008.153015","article-title":"Fluid-flow induces mechanosensitive ATP release, calcium signaling, and Cl\u2212 transport in bilary epithelial cells through a PKC\u00e6-dependent pathway","volume":"586","author":"Woo","year":"2008","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0185","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s11302-009-9146-2","article-title":"ATP release from non-excitable cells","volume":"5","author":"Praetorius","year":"2009","journal-title":"Purinergic Signal"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0190","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1681\/ASN.2008101099","article-title":"Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis","volume":"20","author":"Sipos","year":"2009","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0195","doi-asserted-by":"crossref","first-page":"F216","DOI":"10.1152\/ajprenal.00295.2009","article-title":"Connexin 37 is localized in renal epithelia and responds to changes in dietary salt intake","volume":"298","author":"Stoessel","year":"2010","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0200","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0070-2153(08)00809-0","article-title":"The primary cilium at the crossroads of mammalian hedgehog signaling","volume":"85","author":"Wong","year":"2008","journal-title":"Current Topics in Developmental Biology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0205","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/ncb1670","article-title":"Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms","volume":"10","author":"Corbit","year":"2008","journal-title":"Nature Cell Biology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0210","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1172\/JCI107897","article-title":"Characteristics of the relationship between the flow rate of tubular fluid and potassium transport in the distal tubule of the rat","volume":"54","author":"Kunau","year":"1974","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0215","first-page":"F932","article-title":"Flow dependence of K+ secretion in cortical distal tubules of the rat","volume":"256","author":"Malnic","year":"1989","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0220","first-page":"F817","article-title":"Renal potassium transport: mechanism and regulation","volume":"274","author":"Giebisch","year":"1998","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0225","first-page":"F786","article-title":"Flow-dependent K+ secretion in the cortical collecting duct is mediated by a maxi-K channel","volume":"280","author":"Woda","year":"2001","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0230","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/sj.ki.5002438","article-title":"Two channels for one job","volume":"72","author":"Sansom","year":"2007","journal-title":"Kidney International"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0235","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/sj.ki.5002369","article-title":"The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion","volume":"72","author":"Rieg","year":"2007","journal-title":"Kidney International"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0240","doi-asserted-by":"crossref","first-page":"F389","DOI":"10.1152\/ajprenal.90528.2008","article-title":"K+ secretion in the rat kidney: Na+ channel-dependent and -independent mechanisms","volume":"297","author":"Frindt","year":"2009","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0245","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1681\/ASN.2005101111","article-title":"Distal colonic K+ secretion occurs via BK channels","volume":"17","author":"Sausbier","year":"2006","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0250","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1113\/jphysiol.2004.080002","article-title":"K+ secretion activated by luminal P2Y2 and P2Y4 receptors in mouse colon","volume":"564","author":"Matos","year":"2005","journal-title":"Journal of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0255","doi-asserted-by":"crossref","first-page":"F419","DOI":"10.1152\/ajprenal.00075.2002","article-title":"Control of epithelial transport via luminal P2 receptors","volume":"284","author":"Leipziger","year":"2003","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0260","doi-asserted-by":"crossref","first-page":"F667","DOI":"10.1152\/ajprenal.00458.2005","article-title":"TRPV4 as a flow sensor in flow-dependent K+ secretion from the cortical collecting duct","volume":"292","author":"Taniguchi","year":"2007","journal-title":"American Journal of Physiology: Renal Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0265","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1681\/ASN.2005111171","article-title":"Intraluminal ATP concentrations in rat renal tubules","volume":"17","author":"Vekaria","year":"2006","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0270","doi-asserted-by":"crossref","first-page":"F341","DOI":"10.1152\/ajprenal.00190.2009","article-title":"AVP-stimulated nucleotide secretion in perfused mouse medullary thick ascending limb and cortical collecting duct","volume":"297","author":"Odgaard","year":"2009","journal-title":"American Journal of Physiology: Renal Physiology"},{"issue":"Suppl. 2","key":"10.1016\/j.semcdb.2012.10.003_bib0275","doi-asserted-by":"crossref","first-page":"14531","DOI":"10.1073\/pnas.2235619100","article-title":"Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans","volume":"100","author":"Liedtke","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0280","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/43913","article-title":"A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans","volume":"401","author":"Barr","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0285","doi-asserted-by":"crossref","first-page":"8259","DOI":"10.1523\/JNEUROSCI.17-21-08259.1997","article-title":"OSM-9, a novel protein with structural similarity to channels, is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans","volume":"17","author":"Colbert","year":"1997","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0290","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/S0306-4522(98)00354-6","article-title":"Selective targeting of somatostatin receptor 3 to neuronal cilia","volume":"89","author":"Handel","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0295","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2220\/biomedres.32.73","article-title":"Restricted expression of somatostatin receptor 3 to primary cilia in the pancreatic islets and adenohypophysis of mice","volume":"32","author":"Iwanaga","year":"2011","journal-title":"Biomedical Research"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0300","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/ki.2010.538","article-title":"Bardet\u2013Biedl syndrome highlights the major role of the primary cilium in efficient water reabsorption","volume":"79","author":"Marion","year":"2011","journal-title":"Kidney International"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0305","first-page":"302","article-title":"Mechanism of vasopressin action in the renal collecting duct","volume":"14","author":"Knepper","year":"1994","journal-title":"Seminars in Nephrology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0310","first-page":"F20","article-title":"Electrophysiological study of luminal and basolateral vasopressin in rabbit cortical collecting duct","volume":"268","author":"Naruse","year":"1995","journal-title":"American Journal of Physiology"},{"key":"10.1016\/j.semcdb.2012.10.003_bib0315","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1172\/JCI37041","article-title":"Mechanistic insights into Bardet\u2013Biedl syndrome, a model ciliopathy","volume":"119","author":"Zaghloul","year":"2009","journal-title":"Journal of Clinical Investigation"}],"container-title":["Seminars in Cell & Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952112001838?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952112001838?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T10:10:35Z","timestamp":1643537435000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1084952112001838"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":63,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S1084952112001838"],"URL":"https:\/\/doi.org\/10.1016\/j.semcdb.2012.10.003","relation":{},"ISSN":["1084-9521"],"issn-type":[{"value":"1084-9521","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}