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A."},{"key":"10.1016\/j.semcdb.2015.09.009_bib1455","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1006\/dbio.1997.8721","article-title":"Single-cell analysis of regulatory gene expression in quiescent and activated mouse skeletal muscle satellite cells","volume":"191","author":"Cornelison","year":"1997","journal-title":"Dev. Biol."},{"key":"10.1016\/j.semcdb.2015.09.009_bib1460","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1083\/jcb.200608122","article-title":"Reciprocal inhibition between Pax7 and muscle regulatory factors modulates myogenic cell fate determination","volume":"177","author":"Olguin","year":"2007","journal-title":"J. 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Biol."},{"key":"10.1016\/j.semcdb.2015.09.009_bib1495","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1161\/01.RES.86.12.1187","article-title":"Cytokine actions of angiotensin II","volume":"86","author":"Sadoshima","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.semcdb.2015.09.009_bib1500","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1096\/fasebj.12.10.871","article-title":"Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-kappaB activation in response to tumor necrosis factor alpha","volume":"12","author":"Li","year":"1998","journal-title":"FASEB J."},{"key":"10.1016\/j.semcdb.2015.09.009_bib1505","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1111\/j.1474-9726.2011.00734.x","article-title":"Modulation of reactive oxygen species in skeletal muscle by myostatin is mediated through NF-kappaB","volume":"10","author":"Sriram","year":"2011","journal-title":"Aging Cell"},{"key":"10.1016\/j.semcdb.2015.09.009_bib1510","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.cell.2010.07.011","article-title":"Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival","volume":"142","author":"Zhou","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.semcdb.2015.09.009_bib1515","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1172\/JCI116897","article-title":"Tumor necrosis factor-alpha mediates changes in tissue protein turnover in a rat cancer cachexia model","volume":"92","author":"Costelli","year":"1993","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.semcdb.2015.09.009_bib1520","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/sj.bjc.6602725","article-title":"Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia","volume":"93","author":"Sanders","year":"2005","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.semcdb.2015.09.009_bib1525","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1084\/jem.161.5.984","article-title":"Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells","volume":"161","author":"Beutler","year":"1985","journal-title":"J. Exp. 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