{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:21:27Z","timestamp":1790803287688,"version":"4.1.0"},"reference-count":174,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Cell & Developmental Biology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.semcdb.2016.03.024","type":"journal-article","created":{"date-parts":[[2016,4,9]],"date-time":"2016-04-09T19:01:48Z","timestamp":1460228508000},"page":"126-140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":100,"special_numbering":"C","title":["Effect of environmental contaminants on spermatogenesis"],"prefix":"10.1016","volume":"59","author":[{"given":"Pranitha","family":"Jenardhanan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manivel","family":"Panneerselvam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Premendu P.","family":"Mathur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl. 1","key":"10.1016\/j.semcdb.2016.03.024_bib0005","doi-asserted-by":"crossref","first-page":"S232","DOI":"10.1093\/carcin\/bgv038","article-title":"Environmental immune disruptors, inflammation and cancer risk","volume":"36","author":"Thompson","year":"2015","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0010","first-page":"265","article-title":"Cord blood cells for developmental toxicology and environmental health","volume":"3","author":"Il'yasova","year":"2015","journal-title":"Front. Public Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0015","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.envint.2014.09.006","article-title":"Human health risk associated with brominated flame-retardants (BFRs)","volume":"74","author":"Lyche","year":"2015","journal-title":"Environ. Int."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0020","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/10590501.2014.881648","article-title":"Endoplasmic reticulum stress in drug- and environmental toxicant-induced liver toxicity Journal of environmental science and health Part C","volume":"32","author":"Chen","year":"2014","journal-title":"Environ. Carcinog. Ecotoxicol. Rev."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0025","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1152\/physrev.00017.2015","article-title":"Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility","volume":"96","author":"Skakkebaek","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0030","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3389\/fpubh.2014.00055","article-title":"Exposure to endocrine disrupting chemicals and male reproductive health","volume":"2","author":"Jeng","year":"2014","journal-title":"Front. Public Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0035","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.rbmo.2013.02.005","article-title":"Endocrine-disrupting chemicals and male reproductive health","volume":"26","author":"Knez","year":"2013","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0040","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1530\/REP-15-0355","article-title":"The non-genomic effects of endocrine-disrupting chemicals on mammalian sperm","volume":"151","author":"Tavares","year":"2016","journal-title":"Reproduction"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0045","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1098\/rstb.2009.0206","article-title":"Environmental\/lifestyle effects on spermatogenesis philosophical transactions of the royal society of London series B","volume":"365","author":"Sharpe","year":"2010","journal-title":"Biol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0050","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.mce.2008.04.012","article-title":"Gdnf signaling pathways within the mammalian spermatogonial stem cell niche","volume":"288","author":"Hofmann","year":"2008","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0055","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1152\/physrev.00025.2011","article-title":"The germline stem cell niche unit in mammalian testes","volume":"92","author":"Oatley","year":"2012","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0060","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1016\/j.bbadis.2012.02.008","article-title":"Molecular control of rodent spermatogenesis","volume":"1822","author":"Jan","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0065","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.semcdb.2014.04.007","article-title":"The roles and regulation of Sertoli cells in fate determinations of spermatogonial stem cells and spermatogenesis","volume":"29","author":"Hai","year":"2014","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0070","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/aja.1001720106","article-title":"Ultrastructure of Sertoli-cell penetrating processes found in germ cells of the golden-mantled ground squirrel (spermophilus lateralis)","volume":"172","author":"Vogl","year":"1985","journal-title":"Am. J. Anat."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0075","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1530\/REP-09-0377","article-title":"Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors","volume":"139","author":"O'Shaughnessy","year":"2010","journal-title":"Reproduction"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0080","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1677\/joe.0.0820331","article-title":"Dependence of testicular germ cells on hormones: a quantitative study in hypophysectomized testosterone-treated rats","volume":"82","author":"Chowdhury","year":"1979","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0085","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1210\/en.2009-1278","article-title":"Gonadotropins regulate rat testicular tight junctions in vivo","volume":"151","author":"McCabe","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0090","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1021\/jm00014a017","article-title":"Gonadotropin-releasing hormone antagonists: novel members of the azaline B family","volume":"38","author":"Rivier","year":"1995","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0095","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1210\/jcem.87.7.8675","article-title":"Acyline the first study in humans of a potent, new gonadotropin-releasing hormone antagonist","volume":"87","author":"Herbst","year":"2002","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0100","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1095\/biolreprod.109.078048","article-title":"Changes in gene expression in somatic cells of rat testes resulting from hormonal modulation and radiation-induced germ cell depletion","volume":"82","author":"Zhou","year":"2010","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0105","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1677\/JOE-10-0025","article-title":"Hormonal regulation of male germ cell development","volume":"205","author":"Ruwanpura","year":"2010","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0110","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1098\/rstb.2009.0117","article-title":"Androgens and spermatogenesis: lessons from transgenic mouse models Philosophical transactions of the Royal Society of London Series B","volume":"365","author":"Verhoeven","year":"2010","journal-title":"Biol. Sciences"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0115","doi-asserted-by":"crossref","first-page":"14","DOI":"10.4161\/spmg.1.1.14525","article-title":"Spermiation: the process of sperm release","volume":"1","author":"O'Donnell","year":"2011","journal-title":"Spermatogenesis"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0120","doi-asserted-by":"crossref","first-page":"5074","DOI":"10.1210\/en.2009-0755","article-title":"Transcriptional profiling of the hormone-responsive stages of spermatogenesis reveals cell-, stage-, and hormone-specific events","volume":"150","author":"O'Donnell","year":"2009","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0125","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0012-1606(76)90074-9","article-title":"The Sertoli cell occluding junctions and gap junctions in mature and developing mammalian testis","volume":"50","author":"Gilula","year":"1976","journal-title":"Dev. Biol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0130","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1152\/physrev.00009.2002","article-title":"Cell junction dynamics in the testis: sertoli-germ cell interactions and male contraceptive development","volume":"82","author":"Cheng","year":"2002","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0135","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/10409230903061207","article-title":"An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective","volume":"44","author":"Cheng","year":"2009","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0140","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/nrendo.2010.71","article-title":"A local autocrine axis in the testes that regulates spermatogenesis","volume":"6","author":"Cheng","year":"2010","journal-title":"Nat.Rev. Endocrinol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0145","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1210\/er.2003-0022","article-title":"Sertoli-sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis","volume":"25","author":"Mruk","year":"2004","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0150","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4161\/spmg.1.1.15443","article-title":"Desmosomes in the testis: moving into an unchartered territory","volume":"1","author":"Mruk","year":"2011","journal-title":"Spermatogenesis"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0155","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1095\/biolreprod.110.087452","article-title":"The blood-testis and blood-epididymis barriers are more than just their tight junctions","volume":"84","author":"Mital","year":"2011","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0160","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1098\/rstb.2010.0010","article-title":"Tight junctions in the testis: new perspectives Philosophical transactions of the Royal Society of London Series B","volume":"365","author":"Mruk","year":"2010","journal-title":"Biol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0165","doi-asserted-by":"crossref","first-page":"3493","DOI":"10.4161\/cc.8.21.9833","article-title":"Regulation of blood-testis barrier dynamics by focal adhesion kinase (FAK): an unexpected turn of events","volume":"8","author":"Cheng","year":"2009","journal-title":"Cell Cycle"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0170","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.contraception.2010.03.017","article-title":"New frontiers in nonhormonal male contraception","volume":"82","author":"Cheng","year":"2010","journal-title":"Contraception"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0175","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/humupd\/dmh026","article-title":"Ectoplasmic specialization, a testis-specific cell\u2013cell actin-based adherens junction type: is this a potential target for male contraceptive development","volume":"10","author":"Lee","year":"2004","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0180","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/0040-8166(77)90007-6","article-title":"Observations on rat Sertoli ectoplasmic ('junctional') specializations in their association with germ cells of the rat testis","volume":"9","author":"Russell","year":"1977","journal-title":"Tissue Cell"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.0022-7722.2003.00034.x","article-title":"Ectoplasmic specializations in the Sertoli cell: new vistas based on genetic defects and testicular toxicology","volume":"78","author":"Toyama","year":"2003","journal-title":"Anat. Sci. Int."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0190","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1098\/rstb.2009.0261","article-title":"Cytoskeletal dynamics and spermatogenesis philosophical transactions of the royal society of London series B","volume":"365","author":"Lie","year":"2010","journal-title":"Biol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0195","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1021\/tx500014w","article-title":"Chemical properties, environmental fate, and degradation of seven classes of pollutants","volume":"27","author":"Manzetti","year":"2014","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0200","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1007\/s00244-005-0251-0","article-title":"Ecotoxicity of sediments contaminated by the oil spill associated with the tanker Prestige using juveniles of the fish Sparus aurata","volume":"51","author":"Morales-Caselles","year":"2006","journal-title":"Arch. Environ. Contam. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0205","doi-asserted-by":"crossref","first-page":"e70540","DOI":"10.1371\/journal.pone.0070540","article-title":"Deep-sea benthic footprint of the deepwater horizon blowout","volume":"8","author":"Montagna","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0210","doi-asserted-by":"crossref","first-page":"6440","DOI":"10.1007\/s11356-013-1882-8","article-title":"Exposure of ruminants to persistent organic pollutants and potential of decontamination","volume":"21","author":"Rychen","year":"2014","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0215","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.chemosphere.2012.12.032","article-title":"Accumulation and half-lives of 13 pesticides in muscle tissue of freshwater fishes through food exposure","volume":"91","author":"Lazartigues","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0220","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.chemosphere.2012.11.038","article-title":"Accumulation and detoxification of cadmium by larvae of Prodenia litura (Lepidoptera: noctuidae) feeding on Cd-enriched amaranth leaves","volume":"91","author":"Ding","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0225","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.envint.2011.04.010","article-title":"Bisphenol A (BPA) in China: a review of sources, environmental levels, and potential human health impacts","volume":"42","author":"Huang","year":"2012","journal-title":"Environ. Int."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0230","first-page":"1","article-title":"Plastics in the marine environment: the dark side of a modern gift","volume":"220","author":"Hammer","year":"2012","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0235","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jsbmb.2011.05.002","article-title":"Bisphenol A an endocrine disruptor with widespread exposure and multiple effects","volume":"127","author":"Rubin","year":"2011","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0240","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1001\/jama.2013.283735","article-title":"Handling of thermal receipts as a source of exposure to bisphenol A","volume":"311","author":"Ehrlich","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0245","doi-asserted-by":"crossref","first-page":"9372","DOI":"10.1021\/es202507f","article-title":"Widespread occurrence of bisphenol A in paper and paper products: implications for human exposure","volume":"45","author":"Liao","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0250","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ijheh.2006.09.005","article-title":"Occurrence and daily variation of phthalate metabolites in the urine of an adult population","volume":"210","author":"Fromme","year":"2007","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0255","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ijheh.2011.09.008","article-title":"Human biomonitoring of environmental chemicals-early results of the 2007\u20132009 Canadian Health Measures Survey for males and females","volume":"215","author":"Haines","year":"2012","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0260","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.ijheh.2007.07.011","article-title":"Phthalates toxicology and exposure","volume":"210","author":"Heudorf","year":"2007","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0265","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1289\/ehp.1002727","article-title":"Environmental chemicals in pregnant women in the United States: nHANES 2003\u20132004","volume":"119","author":"Woodruff","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0270","first-page":"407","article-title":"Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A","volume":"17","author":"Vandenberg","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0275","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1289\/ehp.01109675","article-title":"Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels","volume":"109","author":"Rubin","year":"2001","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0280","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1021\/jf505563k","article-title":"Exposure to di-2-ethylhexyl phthalate, di-n-butyl phthalate and bisphenol A through infant formulas","volume":"63","author":"Cirillo","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0285","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/jes.2014.65","article-title":"Bisphenol A and phthalate metabolite urinary concentrations: daily and across pregnancy variability","volume":"25","author":"Fisher","year":"2015","journal-title":"J. Exposure Sci. Environ. Epidemiol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0290","doi-asserted-by":"crossref","first-page":"7537","DOI":"10.3390\/ijerph110707537","article-title":"Bisphenol-A epigenetic reprogramming and effects on reproduction and behavior","volume":"11","author":"Mileva","year":"2014","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0295","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.bbi.2011.02.005","article-title":"Epigenetic perspective on the developmental effects of bisphenol A","volume":"25","author":"Kundakovic","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0300","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/toxsci\/kfi074","article-title":"Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds","volume":"84","author":"Kitamura","year":"2005","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0305","doi-asserted-by":"crossref","first-page":"135","DOI":"10.7555\/JBR.27.20120076","article-title":"Low dose bisphenol A impairs spermatogenesis by suppressing reproductive hormone production and promoting germ cell apoptosis in adult rats","volume":"27","author":"Jin","year":"2013","journal-title":"J. Biomed. Res."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0310","first-page":"57","article-title":"Adverse effects of bisphenol A on male reproductive function","volume":"228","author":"Manfo","year":"2014","journal-title":"Rev. Environ. Contam. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0315","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0300-483X(02)00597-8","article-title":"Induction of oxidative stress by bisphenol A in the epididymal sperm of rats","volume":"185","author":"Chitra","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0320","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1034\/j.1600-0722.2002.11201.x","article-title":"Effects of bisphenol A on adult male mouse fertility","volume":"110","author":"Al-Hiyasat","year":"2002","journal-title":"Eur. J. Oral Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0325","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.tox.2009.09.012","article-title":"Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis","volume":"265","author":"Salian","year":"2009","journal-title":"Toxicology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0330","doi-asserted-by":"crossref","first-page":"263","DOI":"10.3109\/10408444.2011.558487","article-title":"Critical evaluation of key evidence on the human health hazards of exposure to bisphenol A","volume":"41","author":"Hengstler","year":"2011","journal-title":"Crit. Rev. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0335","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11934-012-0261-1","article-title":"An update on phthalates and male reproductive development and function","volume":"13","author":"Grady","year":"2012","journal-title":"Curr. Urol. Rep."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0340","first-page":"2304","article-title":"Role of oxidative stress in male reproductive dysfunctions with reference to phthalate compounds","volume":"12","author":"Sedha","year":"2015","journal-title":"Urol. J."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0345","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1098\/rstb.2008.0281","article-title":"Components of plastic: experimental studies in animals and relevance for human health Philosophical transactions of the Royal Society of London Series B","volume":"364","author":"Talsness","year":"2009","journal-title":"Biol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0350","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1021\/ac000422r","article-title":"Quantitative detection of eight phthalate metabolites in human urine using HPLC-aPCI-MS\/MS","volume":"72","author":"Blount","year":"2000","journal-title":"Anal. Chem."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0355","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1289\/ehp.6235","article-title":"Prenatal exposures to phthalates among women in New York City and Krakow, Poland","volume":"111","author":"Adibi","year":"2003","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0360","doi-asserted-by":"crossref","first-page":"4543","DOI":"10.1021\/es0264596","article-title":"Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust","volume":"37","author":"Rudel","year":"2003","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0365","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1210\/jc.2014-4325","article-title":"Male reproductive disorders, diseases, and costs of exposure to endocrine-disrupting chemicals in the European Union","volume":"100","author":"Hauser","year":"2015","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0370","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1365-2605.2005.00563.x","article-title":"Disruption of reproductive development in male rat offspring following in utero exposure to phthalate esters","volume":"29","author":"Foster","year":"2006","journal-title":"Int. J. Androl."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0375","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1289\/ehp.97105802","article-title":"The estrogenic activity of phthalate esters in vitro","volume":"105","author":"Harris","year":"1997","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0380","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.toxlet.2005.10.020","article-title":"Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis","volume":"163","author":"Borch","year":"2006","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0385","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/humrep\/deg273","article-title":"Human \u2018testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate","volume":"18","author":"Fisher","year":"2003","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0390","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1093\/humrep\/des069","article-title":"Human testis steroidogenesis is inhibited by phthalates","volume":"27","author":"Desdoits-Lethimonier","year":"2012","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0395","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1289\/ehp.8075","article-title":"Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age","volume":"114","author":"Main","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0400","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.reprotox.2011.12.012","article-title":"The effects of different endocrine disruptors defining compound-specific alterations of gene expression profiles in the developing testis","volume":"33","author":"Lopez-Casas","year":"2012","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0405","doi-asserted-by":"crossref","first-page":"e55387","DOI":"10.1371\/journal.pone.0055387","article-title":"Plastics derived endocrine disruptors (BPA, DEHP and DBP) induce epigenetic transgenerational inheritance of obesity, reproductive disease and sperm epimutations","volume":"8","author":"Manikkam","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0410","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1095\/biolreprod.112.106104","article-title":"Transgenerational effects of di-(2-ethylhexyl) phthalate on testicular germ cell associations and spermatogonial stem cells in mice","volume":"88","author":"Doyle","year":"2013","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0415","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0048-9697(91)90016-8","article-title":"Long-term effects of chemical disasters: lessons and results from Seveso","volume":"106","author":"Bertazzi","year":"1991","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0420","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/toxsci\/kfl055","article-title":"The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds","volume":"93","author":"Van den Berg","year":"2006","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0425","first-page":"2893","article-title":"Dioxin-induced changes in epididymal sperm count and spermatogenesis","volume":"16","author":"Foster","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0430","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1080\/10473289.2006.10464575","article-title":"Emissions of polychlorinated dibenzo-p-dioxins and dibenzofurans from various industrial sources","volume":"56","author":"Lin","year":"2006","journal-title":"J. Air Waste Manage. Assoc."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0435","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/S0045-6535(99)00337-9","article-title":"Degradation half-life times of PCDDs, PCDFs and PCBs for environmental fate modeling","volume":"40","author":"Sinkkonen","year":"2000","journal-title":"Chemosphere"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0440","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/00043764-200105000-00002","article-title":"Recent dioxin contamination from Agent Orange in residents of a southern Vietnam city","volume":"43","author":"Schecter","year":"2001","journal-title":"J. Occup. Environ. Med."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0445","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1021\/es00002a010","article-title":"Time trends in levels, patterns, and profiles for polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in a sediment core from the baltic proper","volume":"29","author":"Kjeller","year":"1995","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0450","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.chemosphere.2007.02.032","article-title":"A novel source for dioxins present in recycled fat from gelatin production","volume":"68","author":"Hoogenboom","year":"2007","journal-title":"Chemosphere"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0455","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/152873901750128326","article-title":"Intake of dioxins and related compounds from food in the U: S. population","volume":"63","author":"Schecter","year":"2001","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0460","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/S0045-6535(98)00237-9","article-title":"A comparison of dioxins, dibenzofurans and coplanar PCBs in uncooked and broiled ground beef, catfish and bacon","volume":"37","author":"Schecter","year":"1998","journal-title":"Chemosphere"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0465","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/S0045-6535(97)00441-4","article-title":"Dioxins, dibenzofurans, dioxin-like PCBs, and DDE in U S. fast food, 1995","volume":"34","author":"Schecter","year":"1997","journal-title":"Chemosphere"},{"issue":"Suppl. 2","key":"10.1016\/j.semcdb.2016.03.024_bib0470","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1289\/ehp.98106761","article-title":"Animal models of human response to dioxins","volume":"106","author":"Grassman","year":"1998","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0475","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1080\/009841096161744","article-title":"Pharmacokinetics of TCDD in veterans of operation ranch hand: 10-year follow-up","volume":"47","author":"Michalek","year":"1996","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0480","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1210\/endo.141.1.7374","article-title":"The aryl hydrocarbon receptor, a basic helix-loop-helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse","volume":"141","author":"Robles","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0485","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1093\/toxsci\/kfm283","article-title":"The aryl hydrocarbon receptor affects distinct tissue compartments during ontogeny of the immune system","volume":"102","author":"Hogaboam","year":"2008","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0490","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1081\/DCT-100100114","article-title":"Effects of TCDD on thyroid hormone homeostasis in the rat","volume":"23","author":"Kohn","year":"2000","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0495","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/0041-008X(92)90103-Y","article-title":"In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin: 3. Effects on spermatogenesis and reproductive capability","volume":"114","author":"Mably","year":"1992","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0500","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/toxsci\/kfm272","article-title":"In utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: effects on fetal and adult cardiac gene expression and adult cardiac and renal morphology","volume":"101","author":"Aragon","year":"2008","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0505","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1126\/science.1852076","article-title":"Cloning of a factor required for activity of the Ah (dioxin) receptor","volume":"252","author":"Hoffman","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0510","doi-asserted-by":"crossref","first-page":"5599","DOI":"10.1016\/S0021-9258(20)79769-3","article-title":"Genetic expression of aryl hydrocarbon hydroxylase activity Induction of monooxygenase activities and cytochrome P 1-450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically nonresponsive to other aromatic hydrocarbons","volume":"249","author":"Poland","year":"1974","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0515","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0041-008X(79)90071-1","article-title":"Different effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on glucuronide conjugation of various aglycones: studies in Wistar and Gunn rats","volume":"47","author":"Aitio","year":"1979","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0520","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/S0006-2952(97)00417-6","article-title":"Sustained increase in intracellular free calcium and activation of cyclooxygenase-2 expression in mouse hepatoma cells treated with dioxin","volume":"54","author":"Puga","year":"1997","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0525","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1093\/carcin\/9.12.2285","article-title":"Organ-specific effects of long term feeding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,7,8-pentachlorodibenzo-p-dioxin on I-compounds in hepatic and renal DNA of female Sprague-dawley rats","volume":"9","author":"Randerath","year":"1988","journal-title":"Carcinogenesis"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0530","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.scitotenv.2009.09.044","article-title":"E-waste an assessment of global production and environmental impacts","volume":"408","author":"Robinson","year":"2009","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0535","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/228783a0","article-title":"Metabolic effects of polychlorinated biphenyls in the American kestrel","volume":"228","author":"Lincer","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0540","first-page":"47","article-title":"PCBs: structure-function relationships and mechanism of action","volume":"60","author":"Safe","year":"1985","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0545","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1289\/ehp.94102290","article-title":"Polychlorinated biphenyls as hormonally active structural analogues","volume":"102","author":"McKinney","year":"1994","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0550","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/0272-0590(90)90257-K","article-title":"Role of the Ah locus in suppression of cytotoxic T lymphocyte activity by halogenated aromatic hydrocarbons (PCBs and TCDD): structure-activity relationships and effects in C57Bl\/6 mice congenic at the Ah locus","volume":"14","author":"Kerkvliet","year":"1990","journal-title":"Fundam. Appl. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0555","doi-asserted-by":"crossref","first-page":"4252","DOI":"10.1210\/endo.139.10.6216","article-title":"Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta","volume":"139","author":"Kuiper","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0560","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1289\/ehp.8661","article-title":"PCB-related alteration of thyroid hormones and thyroid hormone receptor gene expression in free-ranging harbor seals (Phoca vitulina)","volume":"114","author":"Tabuchi","year":"2006","journal-title":"Environ. Health Perspect."},{"issue":"Suppl. 4","key":"10.1016\/j.semcdb.2016.03.024_bib0565","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1289\/ehp.99107s4639","article-title":"Characterization of potential endocrine-related health effects at low-dose levels of exposure to PCBs","volume":"107","author":"Brouwer","year":"1999","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0570","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1080\/10715760500308154","article-title":"Studies on the protective role of vitamin C and E against polychlorinated biphenyl (Aroclor 1254)\u2014induced oxidative damage in Leydig cells","volume":"39","author":"Murugesan","year":"2005","journal-title":"Free Radic. Res."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0575","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1515\/reveh-2012-0031","article-title":"Lipophilic chemical exposure as a cause of type 2 diabetes (T2D)","volume":"28","author":"Zeliger","year":"2013","journal-title":"Rev. Environ. Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0580","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1289\/ehp.5461","article-title":"Effects of PCB exposure on neuropsychological function in children","volume":"111","author":"Schantz","year":"2003","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0585","first-page":"181","article-title":"Environmental organochlorine exposure and postmenopausal breast cancer risk","volume":"7","author":"Moysich","year":"1998","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0590","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3109\/19396360903582216","article-title":"Adverse effects of low level heavy metal exposure on male reproductive function","volume":"56","author":"Wirth","year":"2010","journal-title":"Syst. Biol. Reprod. Med."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0595","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1007\/s10534-010-9343-z","article-title":"Cadmium exposure in the population: from health risks to strategies of prevention","volume":"23","author":"Nawrot","year":"2010","journal-title":"Biometals"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0600","doi-asserted-by":"crossref","first-page":"11066","DOI":"10.1007\/s11356-014-2986-5","article-title":"Reproductive toxicity of lead, cadmium, and phthalate exposure in men","volume":"21","author":"Pant","year":"2014","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0605","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.taap.2013.01.016","article-title":"Hexavalent chromium at low concentration alters Sertoli cell barrier and connexin 43 gap junction but not claudin-11 and N-cadherin in the rat seminiferous tubule culture model","volume":"268","author":"Carette","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0610","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0269-7491(90)90072-K","article-title":"Effect of lead, mercury and cadmium on a sulphate-reducing bacterium","volume":"67","author":"Loka Bharathi","year":"1990","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0615","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1365-2613.2009.00692.x","article-title":"Testis response to low doses of cadmium in Wistar rats","volume":"91","author":"de Souza Predes","year":"2010","journal-title":"Int. J. Exp. Pathol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0620","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.fct.2013.01.024","article-title":"Mercuric chloride-induced testicular toxicity in rats and the protective role of sodium selenite and vitamin E","volume":"55","author":"Kalender","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0625","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.toxlet.2011.05.233","article-title":"Effects of maternal cadmium exposure during late pregnant period on testicular steroidogenesis in male offspring","volume":"205","author":"Ji","year":"2011","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0630","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12011-014-0023-7","article-title":"Perspectives in endocrine toxicity of heavy metals\u2013a review","volume":"160","author":"Rana","year":"2014","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0635","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.taap.2009.04.020","article-title":"Current status of cadmium as an environmental health problem","volume":"238","author":"Jarup","year":"2009","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0640","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/15287394.2014.867202","article-title":"Chronic exposure to low doses of mercury impairs sperm quality and induces oxidative stress in rats","volume":"77","author":"Martinez","year":"2014","journal-title":"J. Toxicol. Environ. Health A"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0645","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.etap.2015.08.030","article-title":"Arsenic cardiotoxicity: an overview","volume":"40","author":"Alamolhodaei","year":"2015","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0650","first-page":"0","article-title":"Toxic and genotoxic effects of hexavalent chromium in environment and its bioremediation strategies, Journal of environmental science and health Part C","volume":"2015","author":"Mishra","year":"2016","journal-title":"Environ. Carcinog. Ecotoxicol. Rev."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0655","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.taap.2009.01.028","article-title":"Cadmium-induced testicular injury","volume":"238","author":"Siu","year":"2009","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0660","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1210\/endo.142.5.8145","article-title":"Is cadmium chloride-induced inter-sertoli tight junction permeability barrier disruption a suitable in vitro model to study the events of junction disassembly during spermatogenesis in the rat testis","volume":"142","author":"Chung","year":"2001","journal-title":"Endocrinology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0665","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.reprotox.2009.11.009","article-title":"Cadmium-induced lipid peroxidation and changes in antioxidant defense system in the rat testes: protective role of coenzyme Q(10) and vitamin E","volume":"29","author":"Ognjanovic","year":"2010","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0670","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1007\/s00128-007-9211-x","article-title":"Protective effects of zinc on testes of cadmium-treated rats","volume":"81","author":"Burukoglu","year":"2008","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0675","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1006\/taap.1993.1123","article-title":"A single low cadmium dose causes failure of spermiation in the rat","volume":"121","author":"Hew","year":"1993","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0680","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0300-483X(95)03195-L","article-title":"In vivo studies of cadmium-induced apoptosis in testicular tissue of the rat and its modulation by a chelating agent","volume":"107","author":"Xu","year":"1996","journal-title":"Toxicology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0685","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/1476-069X-6-14","article-title":"Dietary exposure to methyl mercury and PCB and the associations with semen parameters among Swedish fishermen","volume":"6","author":"Rignell-Hydbom","year":"2007","journal-title":"Environ. Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0690","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.cellimm.2010.08.001","article-title":"In vitro and in vivo interactions of aluminum on NTPDase and AChE activities in lymphocytes of rats","volume":"265","author":"Kaizer","year":"2010","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0695","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5271\/sjweh.1060","article-title":"Influence of pesticides on male fertility","volume":"33","author":"Bretveld","year":"2007","journal-title":"Scand. J. Work Environ. Health"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0700","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.toxlet.2014.01.029","article-title":"Occupational exposure to pesticides and consequences on male semen and fertility: a review","volume":"230","author":"Mehrpour","year":"2014","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0705","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1177\/0960327110388959","article-title":"Toxic influence of organophosphate, carbamate, and organochlorine pesticides on cellular metabolism of lipids, proteins, and carbohydrates: a systematic review","volume":"30","author":"Karami-Mohajeri","year":"2011","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0710","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0300-483X(02)00138-5","article-title":"Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis","volume":"176","author":"Latchoumycandane","year":"2002","journal-title":"Toxicology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0715","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1177\/096032719501401106","article-title":"Effect of oral administration of carbofuran on male reproductive system of rat","volume":"14","author":"Pant","year":"1995","journal-title":"Hum. Exp. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0720","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.tox.2008.10.016","article-title":"Lindane induces testicular apoptosis in adult Wistar rats through the involvement of Fas-fasL and mitochondria-dependent pathways","volume":"255","author":"Saradha","year":"2009","journal-title":"Toxicology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0725","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1016\/j.fct.2010.08.027","article-title":"Reproductive toxicity of methomyl insecticide in male rats and protective effect of folic acid","volume":"48","author":"Shalaby","year":"2010","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0730","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1383-5718(01)00146-2","article-title":"Genotoxic effect of 2,4-dichlorophenoxy acetic acid and its metabolite 2,4-dichlorophenol in mouse","volume":"494","author":"Amer","year":"2001","journal-title":"Mutat. Res."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0735","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1439-0272.1989.tb02400.x","article-title":"Ultrastructure of testicular cells in rats treated with dibromochloropropane (DBCP)","volume":"21","author":"Shemi","year":"1989","journal-title":"Andrologia"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0740","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1530\/REP-10-0400","article-title":"Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes","volume":"141","author":"Stouder","year":"2011","journal-title":"Reproduction"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0745","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1196\/annals.1336.004","article-title":"Seminiferous cord formation and germ-cell programming: epigenetic transgenerational actions of endocrine disruptors","volume":"1061","author":"Skinner","year":"2005","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0750","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1006\/taap.1996.0067","article-title":"Fate of germ cells in 2,5-hexanedione-induced testicular injury","volume":"137","author":"Allard","year":"1996","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0755","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/0041-008X(87)90212-2","article-title":"2,5-Hexanedione alters microtubule assembly. I. Testicular atrophy, not nervous system toxicity, correlates with enhanced tubulin polymerization","volume":"88","author":"Koekelheide","year":"1987","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0760","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.semcdb.2014.01.003","article-title":"Microtubules and spermatogenesis","volume":"30","author":"O'Donnell","year":"2014","journal-title":"Semin. Dev. Biol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0765","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1095\/biolreprod64.3.946","article-title":"Expression of Fas and Fas ligand in normal and ischemia-reperfusion testes: involvement of the Fas system in the induction of germ cell apoptosis in the damaged mouse testis","volume":"64","author":"Koji","year":"2001","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0770","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1006\/bbrc.2002.6644","article-title":"Bisphenol A induces apoptosis and G2-to-m arrest of ovarian granulosa cells","volume":"292","author":"Xu","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0775","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/toxsci\/kft198","article-title":"Endocrine disruptors differentially target ATP-binding cassette transporters in the blood-testis barrier and affect Leydig cell testosterone secretion in vitro","volume":"136","author":"Dankers","year":"2013","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0780","doi-asserted-by":"crossref","first-page":"e106245","DOI":"10.1371\/journal.pone.0106245","article-title":"Exposure to low-dose bisphenol A impairs meiosis in the rat seminiferous tubule culture model: a physiotoxicogenomic approach","volume":"9","author":"Ali","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0785","doi-asserted-by":"crossref","first-page":"e676","DOI":"10.1038\/cddis.2013.203","article-title":"Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity","volume":"4","author":"Liu","year":"2013","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0790","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/jat.3188","article-title":"The toxic effects of Bisphenol A on the mouse spermatocyte GC-2 cell line: the role of the Ca2+-calmodulin-ca2+\/calmodulin-dependent protein kinase II axis","volume":"35","author":"Qian","year":"2015","journal-title":"J. Appl. Toxicol.: JAT"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0795","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.fct.2011.11.041","article-title":"impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: an in vivo and in silico study","volume":"50","author":"D'Cruz","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0800","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1177\/1933719111415547","article-title":"Bisphenol A induces oxidative stress and decreases levels of insulin receptor substrate 2 and glucose transporter 8 in rat testis","volume":"19","author":"D'Cruz","year":"2012","journal-title":"Reprod. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0805","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1016\/j.biocel.2009.05.016","article-title":"Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?","volume":"41","author":"Li","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0810","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1517\/14728222.2015.1039513","article-title":"Sertoli cells are the target of environmental toxicants in the testis\u2014a mechanistic and therapeutic insight","volume":"19","author":"Gao","year":"2015","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0815","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1007\/s13105-011-0102-6","article-title":"Probable gamma-aminobutyric acid involvement in bisphenol A effect at the hypothalamic level in adult male rats","volume":"67","author":"Cardoso","year":"2011","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0820","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1177\/153537020122600309","article-title":"Bisphenol A inhibits testicular functions and increases luteinizing hormone secretion in adult male rats","volume":"226","author":"Tohei","year":"2001","journal-title":"Exp. Biol. Med."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0825","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.toxlet.2010.02.002","article-title":"Bisphenol A may cause testosterone reduction by adversely affecting both testis and pituitary systems similar to estradiol","volume":"194","author":"Nakamura","year":"2010","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0830","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.lfs.2009.10.004","article-title":"Perinatal exposure of rats to bisphenol A affects the fertility of male offspring","volume":"85","author":"Salian","year":"2009","journal-title":"Life Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0835","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/toxsci\/kfg087","article-title":"Quantitative changes in gene expression in fetal rat testes following exposure to di(n-butyl) phthalate","volume":"73","author":"Barlow","year":"2003","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0840","doi-asserted-by":"crossref","first-page":"6509","DOI":"10.1007\/s11033-013-2769-y","article-title":"Effects of diethylhexyl phthalate (DEHP) given neonatally on spermatogenesis of mice","volume":"40","author":"Zhang","year":"2013","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0845","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0378-4274(01)00348-4","article-title":"The acute effects of mono(2-ethylhexyl)phthalate (MEHP) on testes of prepubertal Wistar rats","volume":"122","author":"Dalgaard","year":"2001","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0850","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.bbagrm.2014.08.006","article-title":"A chromatin modifier regulates Sertoli cell response to mono-(2-ethylhexyl) phthalate (MEHP) via tissue inhibitor of metalloproteinase 2 (TIMP2) signaling","volume":"1839","author":"Zhang","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0855","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/j.febslet.2008.02.013","article-title":"Metastasis tumor antigen 1 is involved in the resistance to heat stress-induced testicular apoptosis","volume":"582","author":"Li","year":"2008","journal-title":"FEBS Lett."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0860","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.urology.2012.07.034","article-title":"Presence of metastasis-associated protein 1 in Sertoli cells is required for proper contact between Sertoli cells and adjacent germ cells","volume":"81","author":"Sun","year":"2013","journal-title":"Urology"},{"key":"10.1016\/j.semcdb.2016.03.024_bib0865","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2174\/1874467208666150126155420","article-title":"Effect of environmental contaminants on mammalian testis","volume":"7","author":"Manfo","year":"2014","journal-title":"Curr. Mol. Pharmacol."},{"key":"10.1016\/j.semcdb.2016.03.024_bib0870","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.toxlet.2004.07.015","article-title":"Cadmium at a non-toxic dose alters gene expression in mouse testes","volume":"154","author":"Zhou","year":"2004","journal-title":"Toxicol. Lett."}],"container-title":["Seminars in Cell & Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952116300854?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952116300854?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T13:29:39Z","timestamp":1655472579000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1084952116300854"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":174,"alternative-id":["S1084952116300854"],"URL":"https:\/\/doi.org\/10.1016\/j.semcdb.2016.03.024","relation":{},"ISSN":["1084-9521"],"issn-type":[{"value":"1084-9521","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of environmental contaminants on spermatogenesis","name":"articletitle","label":"Article Title"},{"value":"Seminars in Cell & Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semcdb.2016.03.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}