{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:53:06Z","timestamp":1789555986932,"version":"build-2803163510"},"reference-count":85,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Cell &amp; Developmental Biology"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.semcdb.2016.12.008","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T02:17:29Z","timestamp":1482113849000},"page":"25-35","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"special_numbering":"C","title":["Development and stem cells of the esophagus"],"prefix":"10.1016","volume":"66","author":[{"given":"Yongchun","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sijie","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuancan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaopeng","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwen","family":"Que","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.semcdb.2016.12.008_bib0005","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/wdev.179","article-title":"The initial establishment and epithelial morphogenesis of the esophagus: a new model of tracheal-esophageal separation and transition of simple columnar into stratified squamous epithelium in the developing esophagus","volume":"4","author":"Que","year":"2015","journal-title":"Wiley Interdiscip. Rev. Dev. Biol."},{"issue":"13","key":"10.1016\/j.semcdb.2016.12.008_bib0010","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1242\/dev.003855","article-title":"Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm","volume":"134","author":"Que","year":"2007","journal-title":"Development"},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0015","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1242\/dev.053694","article-title":"Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2","volume":"138","author":"Domyan","year":"2011","journal-title":"Development"},{"issue":"4","key":"10.1016\/j.semcdb.2016.12.008_bib0020","doi-asserted-by":"crossref","DOI":"10.1242\/dev.113.4.1093","article-title":"The transcription factor-Ttf-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the fetal brain","volume":"113","author":"Lazzaro","year":"1991","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0025","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1242\/dev.01570","article-title":"Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung","volume":"132","author":"Serls","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.semcdb.2016.12.008_bib0030","series-title":"Comparative Anatomy and Histology: A Mouse and Human Atlas","author":"Treuting","year":"2012"},{"issue":"10","key":"10.1016\/j.semcdb.2016.12.008_bib0035","doi-asserted-by":"crossref","first-page":"2818","DOI":"10.1111\/j.1572-0241.1999.1422_b.x","article-title":"Esophageal submucosal glands: structure and function","volume":"94","author":"Long","year":"1999","journal-title":"Am. J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0040","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ydbio.2012.06.016","article-title":"Genetic and cellular mechanisms regulating anterior foregut and esophageal development","volume":"369","author":"Jacobs","year":"2012","journal-title":"Dev. Biol."},{"issue":"7","key":"10.1016\/j.semcdb.2016.12.008_bib0045","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/j.1432-0436.2006.00096.x","article-title":"Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps","volume":"74","author":"Que","year":"2006","journal-title":"Differentiation"},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0050","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ydbio.2009.11.005","article-title":"Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death","volume":"337","author":"Ioannides","year":"2010","journal-title":"Dev. Biol."},{"issue":"3","key":"10.1016\/j.semcdb.2016.12.008_bib0055","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1053\/j.sempedsurg.2011.03.004","article-title":"Embryology of the early foregut","volume":"20","author":"Metzger","year":"2011","journal-title":"Semin. Pediatr. Surg."},{"issue":"3","key":"10.1016\/j.semcdb.2016.12.008_bib0060","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.jpeds.2008.03.034","article-title":"Longitudinal follow-up of bronchial inflammation, respiratory symptoms, and pulmonary function in adolescents after repair of esophageal atresia with tracheoesophageal fistula","volume":"153","author":"Malmstrom","year":"2008","journal-title":"J. Pediatr."},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0065","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/ppul.1950200105","article-title":"Late pulmonary function following repair of tracheoesophageal fistula or esophageal atresia","volume":"20","author":"Robertson","year":"1995","journal-title":"Pediatr. Pulmonol."},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0070","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1183\/09031936.00153209","article-title":"Repaired oesophageal atresia: respiratory morbidity and pulmonary function in adults","volume":"36","author":"Sistonen","year":"2010","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.semcdb.2016.12.008_bib0075","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3389\/fped.2014.00039","article-title":"The multifactorial origin of respiratory morbidity in patients surviving neonatal repair of esophageal atresia","volume":"2","author":"Fragoso","year":"2014","journal-title":"Front. Pediatr."},{"issue":"38","key":"10.1016\/j.semcdb.2016.12.008_bib0080","doi-asserted-by":"crossref","first-page":"16287","DOI":"10.1073\/pnas.0902274106","article-title":"beta-catenin promotes respiratory progenitor identity in mouse foregut","volume":"106","author":"Harris-Johnson","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0085","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1101\/gad.224503","article-title":"Multipotent cell lineages in early mouse development depend on SOX2 function","volume":"17","author":"Avilion","year":"2003","journal-title":"Genes Dev."},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0090","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.cellsig.2013.02.013","article-title":"The multiple roles for Sox2 in stem cell maintenance and tumorigenesis","volume":"25","author":"Liu","year":"2013","journal-title":"Cell. Signal."},{"issue":"9","key":"10.1016\/j.semcdb.2016.12.008_bib0095","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1093\/hmg\/ddl064","article-title":"Mutations in SOX2 cause anophthalmia-esophageal-genital (AEG) syndrome","volume":"15","author":"Williamson","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.semcdb.2016.12.008_bib0100","unstructured":"H. Kondoh, R. Lovell-Badge, Sox2: biology and role in development and disease, Academic Press, (2016)."},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0105","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1006\/dbio.1999.9234","article-title":"Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-\/-) mouse embryos","volume":"209","author":"Minoo","year":"1999","journal-title":"Dev. Biol."},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0110","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0896-6273(03)00497-5","article-title":"SOX2 functions to maintain neural progenitor identity","volume":"39","author":"Graham","year":"2003","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0115","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/emboj.2011.416","article-title":"MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis","volume":"31","author":"Hosono","year":"2012","journal-title":"EMBO J."},{"issue":"12","key":"10.1016\/j.semcdb.2016.12.008_bib0120","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1242\/dev.128.12.2397","article-title":"Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations","volume":"128","author":"Mahlapuu","year":"2001","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0125","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.celrep.2016.05.060","article-title":"A retinoic acid-hedgehog cascade coordinates mesoderm-inducing signals and endoderm competence during lung specification","volume":"16","author":"Rankin","year":"2016","journal-title":"Cell Rep."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0130","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.devcel.2009.06.005","article-title":"Wnt2\/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut","volume":"17","author":"Goss","year":"2009","journal-title":"Dev. Cell"},{"issue":"7","key":"10.1016\/j.semcdb.2016.12.008_bib0135","doi-asserted-by":"crossref","first-page":"e22493","DOI":"10.1371\/journal.pone.0022493","article-title":"Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation","volume":"6","author":"Woo","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0140","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ydbio.2008.07.021","article-title":"Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis","volume":"322","author":"Li","year":"2008","journal-title":"Dev. Biol."},{"issue":"3","key":"10.1016\/j.semcdb.2016.12.008_bib0145","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1002\/dvdy.21075","article-title":"Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresia","volume":"236","author":"Li","year":"2007","journal-title":"Dev. Dyn."},{"issue":"20","key":"10.1016\/j.semcdb.2016.12.008_bib0150","doi-asserted-by":"crossref","first-page":"4831","DOI":"10.1242\/dev.129.20.4831","article-title":"Wnt7b regulates mesenchymal proliferation and vascular development in the lung","volume":"129","author":"Shu","year":"2002","journal-title":"Development"},{"issue":"24","key":"10.1016\/j.semcdb.2016.12.008_bib0155","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1242\/dev.056077","article-title":"BMP signaling in the development of the mouse esophagus and forestomach","volume":"137","author":"Rodriguez","year":"2010","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0160","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/1717","article-title":"Sonic hedgehog is essential to foregut development","volume":"20","author":"Litingtung","year":"1998","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0165","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/1711","article-title":"Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus","volume":"20","author":"Motoyama","year":"1998","journal-title":"Nat. Genet."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0170","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/aja.1000920202","article-title":"An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation","volume":"92","author":"Wilson","year":"1953","journal-title":"Am. J. Anat."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0175","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.ydbio.2006.05.019","article-title":"Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives","volume":"297","author":"Wang","year":"2006","journal-title":"Dev. Biol."},{"issue":"16","key":"10.1016\/j.semcdb.2016.12.008_bib0180","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1242\/dev.006221","article-title":"Inhibition of Tgf beta signaling by endogenous retinoic acid is essential for primary lung bud induction","volume":"134","author":"Chen","year":"2007","journal-title":"Development"},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0185","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ydbio.2005.04.042","article-title":"Conversion of columnar to stratified squamous epithelium in the developing mouse oesophagus","volume":"284","author":"Yu","year":"2005","journal-title":"Dev. Biol."},{"issue":"3","key":"10.1016\/j.semcdb.2016.12.008_bib0190","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/nrg758","article-title":"Getting under the skin of epidermal morphogenesis","volume":"3","author":"Fuchs","year":"2002","journal-title":"Nat. Rev. Genet."},{"issue":"7130","key":"10.1016\/j.semcdb.2016.12.008_bib0195","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/nature05659","article-title":"Scratching the surface of skin development","volume":"445","author":"Fuchs","year":"2007","journal-title":"Nature"},{"issue":"6729","key":"10.1016\/j.semcdb.2016.12.008_bib0200","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/19531","article-title":"p63 is a p53 homologue required for limb and epidermal morphogenesis","volume":"398","author":"Mills","year":"1999","journal-title":"Nature"},{"issue":"6729","key":"10.1016\/j.semcdb.2016.12.008_bib0205","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/19539","article-title":"p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development","volume":"398","author":"Yang","year":"1999","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0210","doi-asserted-by":"crossref","first-page":"C171","DOI":"10.1152\/ajpcell.00226.2003","article-title":"Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium","volume":"287","author":"Daniely","year":"2004","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0215","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1101\/gad.1165104","article-title":"p63 is the molecular switch for initiation of an epithelial stratification program","volume":"18","author":"Koster","year":"2004","journal-title":"Genes Dev."},{"issue":"7","key":"10.1016\/j.semcdb.2016.12.008_bib0220","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.cell.2011.05.026","article-title":"Residual embryonic cells as precursors of a Barrett's-like metaplasia","volume":"145","author":"Wang","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.semcdb.2016.12.008_bib0225","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1146\/annurev-pathol-121808-102117","article-title":"p63 in epithelial survival, germ cell surveillance, and neoplasia","volume":"5","author":"Crum","year":"2010","journal-title":"Annu. Rev. Pathol."},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0230","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1101\/gad.1190504","article-title":"p63 and the epithelial stem cell: more than status quo?","volume":"18","author":"McKeon","year":"2004","journal-title":"Genes Dev."},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0235","doi-asserted-by":"crossref","first-page":"e5623","DOI":"10.1371\/journal.pone.0005623","article-title":"An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate","volume":"4","author":"Romano","year":"2009","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.semcdb.2016.12.008_bib0240","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1242\/dev.071191","article-title":"DeltaNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation","volume":"139","author":"Romano","year":"2012","journal-title":"Development"},{"issue":"20","key":"10.1016\/j.semcdb.2016.12.008_bib0245","doi-asserted-by":"crossref","first-page":"8105","DOI":"10.1073\/pnas.1221216110","article-title":"p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia","volume":"110","author":"Pignon","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"16","key":"10.1016\/j.semcdb.2016.12.008_bib0250","doi-asserted-by":"crossref","first-page":"2815","DOI":"10.1242\/dev.038620","article-title":"Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis","volume":"136","author":"Driskell","year":"2009","journal-title":"Development"},{"issue":"11","key":"10.1016\/j.semcdb.2016.12.008_bib0255","doi-asserted-by":"crossref","first-page":"e331","DOI":"10.1371\/journal.pbio.0030331","article-title":"Molecular dissection of mesenchymal-epithelial interactions in the hair follicle","volume":"3","author":"Rendl","year":"2005","journal-title":"PLoS Biol."},{"issue":"4","key":"10.1016\/j.semcdb.2016.12.008_bib0260","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1172\/JCI78850","article-title":"BMP-driven NRF2 activation in esophageal basal cell differentiation and eosinophilic esophagitis","volume":"125","author":"Jiang","year":"2015","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0265","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.celrep.2014.09.027","article-title":"Cellular heterogeneity in the mouse esophagus implicates the presence of a nonquiescent epithelial stem cell population","volume":"9","author":"DeWard","year":"2014","journal-title":"Cell Rep."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0270","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.cell.2009.03.045","article-title":"The canonical Notch signaling pathway: unfolding the activation mechanism","volume":"137","author":"Kopan","year":"2009","journal-title":"Cell"},{"issue":"21","key":"10.1016\/j.semcdb.2016.12.008_bib0275","doi-asserted-by":"crossref","first-page":"3022","DOI":"10.1101\/gad.1477606","article-title":"Canonical Notch signaling functions as a commitment switch in the epidermal lineage","volume":"20","author":"Blanpain","year":"2006","journal-title":"Gene Dev."},{"issue":"6","key":"10.1016\/j.semcdb.2016.12.008_bib0280","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1053\/j.gastro.2010.08.040","article-title":"NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network","volume":"139","author":"Ohashi","year":"2010","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.semcdb.2016.12.008_bib0285","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/ajg.2011.102","article-title":"Role of E-cadherin in the pathogenesis of gastroesophageal reflux disease","volume":"106","author":"Jovov","year":"2011","journal-title":"Am. J. Gastroenterol."},{"issue":"22","key":"10.1016\/j.semcdb.2016.12.008_bib0290","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/S0960-9822(00)00803-4","article-title":"Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium","volume":"10","author":"Seery","year":"2000","journal-title":"Curr. Biol."},{"issue":"12","key":"10.1016\/j.semcdb.2016.12.008_bib0295","first-page":"3860","article-title":"A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification","volume":"118","author":"Kalabis","year":"2008","journal-title":"J. Clin. Invest."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0300","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1634\/stemcells.2006-0421","article-title":"Identification of candidate murine esophageal stem cells using a combination of cell kinetic studies and cell surface markers","volume":"25","author":"Croagh","year":"2007","journal-title":"Stem Cells"},{"issue":"3","key":"10.1016\/j.semcdb.2016.12.008_bib0305","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.stem.2013.01.007","article-title":"Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells","volume":"12","author":"Liu","year":"2013","journal-title":"Cell Stem Cell"},{"issue":"9","key":"10.1016\/j.semcdb.2016.12.008_bib0310","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/ncb3400","article-title":"A single dividing cell population with imbalanced fate drives oesophageal tumour growth","volume":"18","author":"Frede","year":"2016","journal-title":"Nat. Cell Biol."},{"issue":"6098","key":"10.1016\/j.semcdb.2016.12.008_bib0315","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1126\/science.1218835","article-title":"A single progenitor population switches behavior to maintain and repair esophageal epithelium","volume":"337","author":"Doupe","year":"2012","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.semcdb.2016.12.008_bib0320","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/ncb2963","article-title":"Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change","volume":"16","author":"Alcolea","year":"2014","journal-title":"Nat. Cell Biol."},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0325","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/00004836-198604000-00005","article-title":"Muscle anatomy of the human esophagus","volume":"8","author":"Meyer","year":"1986","journal-title":"J. Clin. Gastroenterol."},{"issue":"8","key":"10.1016\/j.semcdb.2016.12.008_bib0330","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1242\/dev.127.8.1627","article-title":"Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent","volume":"127","author":"Kablar","year":"2000","journal-title":"Development"},{"issue":"4","key":"10.1016\/j.semcdb.2016.12.008_bib0335","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1442-2050.2011.01180.x","article-title":"Anatomy and physiology of the esophageal body","volume":"25","author":"Yazaki","year":"2012","journal-title":"Dis. Esophagus"},{"issue":"32","key":"10.1016\/j.semcdb.2016.12.008_bib0340","doi-asserted-by":"crossref","first-page":"4317","DOI":"10.3748\/wjg.v18.i32.4317","article-title":"Circular smooth muscle contributes to esophageal shortening during peristalsis","volume":"18","author":"Vegesna","year":"2012","journal-title":"World J. Gastroenterol."},{"issue":"Suppl. 1","key":"10.1016\/j.semcdb.2016.12.008_bib0345","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1365-2982.2005.00661.x","article-title":"The lower oesophageal sphincter","volume":"17","author":"Boeckxstaens","year":"2005","journal-title":"Neurogastroenterol. Motil."},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0350","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0016-5085(76)80098-4","article-title":"Genesis of basal sphincter pressure: effect of tetrodotoxin on lower esophageal sphincter pressure in opossum in vivo","volume":"71","author":"Goyal","year":"1976","journal-title":"Gastroenterology"},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0355","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1053\/j.gastro.2008.02.031","article-title":"A unique longitudinal muscle contraction pattern associated with transient lower esophageal sphincter relaxation","volume":"134","author":"Babaei","year":"2008","journal-title":"Gastroenterology"},{"issue":"6","key":"10.1016\/j.semcdb.2016.12.008_bib0360","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1111\/j.1572-0241.2005.41775.x","article-title":"Etiology and pathogenesis of achalasia: the current understanding","volume":"100","author":"Park","year":"2005","journal-title":"Am. J. Gastroenterol."},{"issue":"4","key":"10.1016\/j.semcdb.2016.12.008_bib0365","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/00005176-199611000-00001","article-title":"Molecular analysis of gastrointestinal smooth muscle development","volume":"23","author":"McHugh","year":"1996","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"issue":"3","key":"10.1016\/j.semcdb.2016.12.008_bib0370","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1002\/aja.1002040306","article-title":"Molecular analysis of smooth muscle development in the mouse","volume":"204","author":"McHugh","year":"1995","journal-title":"Dev. Dyn."},{"issue":"1","key":"10.1016\/j.semcdb.2016.12.008_bib0375","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/(SICI)1096-9861(19970915)386:1<119::AID-CNE11>3.0.CO;2-F","article-title":"Development of nicotinic receptor clusters and innervation accompanying the change in muscle phenotype in the mouse esophagus","volume":"386","author":"Sang","year":"1997","journal-title":"J. Comp. Neurol."},{"issue":"5","key":"10.1016\/j.semcdb.2016.12.008_bib0380","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/BF00304424","article-title":"Early stages of chick somite development","volume":"191","author":"Christ","year":"1995","journal-title":"Anat. Embryol. (Berl.)"},{"issue":"5243","key":"10.1016\/j.semcdb.2016.12.008_bib0385","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1126\/science.270.5243.1818","article-title":"Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle","volume":"270","author":"Patapoutian","year":"1995","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0390","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/gene.10198","article-title":"Skeletal myogenesis in the mouse esophagus does not occur through transdifferentiation","volume":"36","author":"Rishniw","year":"2003","journal-title":"Genesis"},{"issue":"6","key":"10.1016\/j.semcdb.2016.12.008_bib0395","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.devcel.2015.07.003","article-title":"A cranial mesoderm origin for esophagus striated muscles","volume":"34","author":"Gopalakrishnan","year":"2015","journal-title":"Dev. Cell"},{"issue":"4","key":"10.1016\/j.semcdb.2016.12.008_bib0400","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1242\/dev.007989","article-title":"The contribution of Islet1-expressing splanchnic mesoderm cells to distinct branchiomeric muscles reveals significant heterogeneity in head muscle development","volume":"135","author":"Nathan","year":"2008","journal-title":"Development"},{"issue":"7044","key":"10.1016\/j.semcdb.2016.12.008_bib0405","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1038\/nature03594","article-title":"A Pax3\/Pax7-dependent population of skeletal muscle progenitor cells","volume":"435","author":"Relaix","year":"2005","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.semcdb.2016.12.008_bib0410","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1083\/jcb.201301005","article-title":"Smooth muscle fascicular reorientation is required for esophageal morphogenesis and dependent on Cdo","volume":"201","author":"Romer","year":"2013","journal-title":"J. Cell Biol."},{"issue":"13","key":"10.1016\/j.semcdb.2016.12.008_bib0415","doi-asserted-by":"crossref","first-page":"4761","DOI":"10.1523\/JNEUROSCI.21-13-04761.2001","article-title":"Progressive cerebellar, auditory, and esophageal dysfunction caused by targeted disruption of the frizzled-4 gene","volume":"21","author":"Wang","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.semcdb.2016.12.008_bib0420","doi-asserted-by":"crossref","DOI":"10.1186\/s13395-015-0068-0","article-title":"PAX7 is required for patterning the esophageal musculature","volume":"5","author":"Chihara","year":"2015","journal-title":"Skelet. Muscle"},{"issue":"10","key":"10.1016\/j.semcdb.2016.12.008_bib0425","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1242\/dev.02846","article-title":"Foxp2 and Foxp1 cooperatively regulate lung and esophagus development","volume":"134","author":"Shu","year":"2007","journal-title":"Development"}],"container-title":["Seminars in Cell &amp; Developmental Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952116304827?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1084952116304827?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,17]],"date-time":"2022-07-17T21:19:03Z","timestamp":1658092743000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1084952116304827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":85,"alternative-id":["S1084952116304827"],"URL":"https:\/\/doi.org\/10.1016\/j.semcdb.2016.12.008","relation":{},"ISSN":["1084-9521"],"issn-type":[{"value":"1084-9521","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development and stem cells of the esophagus","name":"articletitle","label":"Article Title"},{"value":"Seminars in Cell & Developmental Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semcdb.2016.12.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}