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Chem."},{"key":"10.1016\/j.semcdb.2021.07.007_bib80","article-title":"Cyclin D2 overexpression enhances the efficacy of human induced pluripotent stem cell-derived cardiomyocytes for myocardial repair in a Swine model of myocardial infarction","author":"Zhao","year":"2021","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.semcdb.2021.07.007_bib81","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.114.000946","article-title":"Single intracoronary injection of encapsulated antagomir\u201092a promotes angiogenesis and prevents adverse infarct remodeling.","volume":"3","author":"Bellera","year":"2014","journal-title":"J. Am. 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