{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T01:27:14Z","timestamp":1785547634580,"version":"3.56.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Diagnostic Pathology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.semdp.2025.150940","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T15:36:16Z","timestamp":1750779376000},"page":"150940","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Keratocystoma: Molecular insights and diagnostic challenges in a rare salivary gland tumor"],"prefix":"10.1016","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8462-1255","authenticated-orcid":false,"given":"Yoshitaka","family":"Utsumi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Nakaguro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin A.","family":"Bishop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2075-9738","authenticated-orcid":false,"given":"Toshitaka","family":"Nagao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semdp.2025.150940_bib0001","series-title":"WHO Classification of Tumours Editorial Board ed","first-page":"198","article-title":"Keratocystoma","author":"Nagao","year":"2024"},{"key":"10.1016\/j.semdp.2025.150940_bib0002","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s004280050352","article-title":"Unusual choristoma of the parotid gland in a girl. A possible trichoadenoma","volume":"434","author":"Seifert","year":"1999","journal-title":"Virchows Arch"},{"key":"10.1016\/j.semdp.2025.150940_bib0003","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1097\/01.MP.0000026053.67284.A3","article-title":"Keratocystoma of the parotid gland: a report of two cases of an unusual pathologic entity","volume":"15","author":"Nagao","year":"2002","journal-title":"Mod Pathol"},{"key":"10.1016\/j.semdp.2025.150940_bib0004","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1136\/jcp.2010.076521","article-title":"Keratocystoma of the parotid gland: case report and immunohistochemical investigation","volume":"63","author":"Zhang","year":"2010","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.semdp.2025.150940_bib0005","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ijom.2011.12.009","article-title":"Keratocystoma of the parotid gland: a clinicopathological study and literature review","volume":"41","author":"Huang","year":"2012","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.semdp.2025.150940_bib0006","article-title":"Radiological images of keratocystoma: a rare tumor of the parotid gland","volume":"3","author":"Hirata","year":"2014","journal-title":"Acta Radiol Short Rep"},{"key":"10.1016\/j.semdp.2025.150940_bib0007","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.bjoms.2015.04.005","article-title":"Keratocystoma of the parotid gland: a case report and review of previous publications","volume":"53","author":"Wang","year":"2015","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.semdp.2025.150940_bib0008","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/2454-3160.202125","article-title":"Keratocystoma of minor salivary gland of the palate","volume":"2","author":"Ahuja","year":"2016","journal-title":"Saint\u2019s Int Dental J"},{"key":"10.1016\/j.semdp.2025.150940_bib0009","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1002\/dc.24161","article-title":"Keratocystoma of the parotid gland is rare and requires an integrated multidisciplinary approach: report of a case and a literature review","volume":"47","author":"Aresta","year":"2019","journal-title":"Diagn Cytopathol"},{"key":"10.1016\/j.semdp.2025.150940_bib0010","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.anl.2019.05.006","article-title":"Keratocystoma of the parotid gland","volume":"47","author":"Komatsu","year":"2020","journal-title":"Auris Nasus Larynx"},{"key":"10.1016\/j.semdp.2025.150940_bib0011","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2022-252039","article-title":"Parotid gland keratocystoma: a rare diagnosis of a neck lump","volume":"15","author":"Anparasan","year":"2022","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.semdp.2025.150940_bib0012","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2022-249528","article-title":"Cystic lesion in parotid region: an unexpected diagnosis","volume":"15","author":"Saraniti","year":"2022","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.semdp.2025.150940_bib0013","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1097\/PAS.0000000000002169","article-title":"Keratocystoma: a distinctive salivary gland neoplasm characterized by RUNX2 rearrangements","volume":"48","author":"Bishop","year":"2024","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.semdp.2025.150940_bib0014","doi-asserted-by":"crossref","DOI":"10.1177\/01455613241287012","article-title":"Keratocystoma of the Parotid gland: a rare case and review of the literature","author":"Liu","year":"2024","journal-title":"Ear Nose Throat J"},{"key":"10.1016\/j.semdp.2025.150940_bib0015","doi-asserted-by":"crossref","first-page":"E61","DOI":"10.1002\/dc.25438","article-title":"Parotid keratocystoma: fine needle aspiration cytomorphology with ancillary testing results","volume":"53","author":"Klijanienko","year":"2025","journal-title":"Diagn Cytopathol"},{"key":"10.1016\/j.semdp.2025.150940_bib0016","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/s12105-024-01714-6","article-title":"Comprehensive next generation sequencing reveals that purported primary squamous cell carcinomas of the parotid gland are genetically heterogeneous","volume":"18","author":"Bishop","year":"2024","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.semdp.2025.150940_bib0017","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00428-024-03798-5","article-title":"Metastatic cutaneous squamous cell carcinoma accounts for nearly all squamous cell carcinomas of the parotid gland","volume":"485","author":"Bradley","year":"2024","journal-title":"Virchows Arch"},{"key":"10.1016\/j.semdp.2025.150940_bib0018","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1053\/j.semdp.2024.04.001","article-title":"Expanding the cytological and architectural spectrum of mucoepidermoid carcinoma: the key to solving diagnostic problems in morphological variants","volume":"41","author":"Sakamoto","year":"2024","journal-title":"Semin Diagn Pathol"},{"key":"10.1016\/j.semdp.2025.150940_bib0019","doi-asserted-by":"crossref","first-page":"411","DOI":"10.4132\/jptm.2018.07.15","article-title":"Squamous metaplasia in pleomorphic adenoma: a diagnostic and prognostic enigma","volume":"52","author":"Sharma","year":"2018","journal-title":"J Pathol Transl Med"},{"key":"10.1016\/j.semdp.2025.150940_bib0020","doi-asserted-by":"crossref","DOI":"10.12659\/AJCR.939411","article-title":"Dermoid cyst of the parotid gland: case report of a rare entity and review of the literature","volume":"24","author":"Alhusain","year":"2023","journal-title":"Am J Case Rep"},{"key":"10.1016\/j.semdp.2025.150940_bib0021","first-page":"110","article-title":"Parotid masses in patients with previous ear surgery","volume":"98","author":"Walshe","year":"2005","journal-title":"Ir Med J"},{"key":"10.1016\/j.semdp.2025.150940_bib0022","article-title":"Parotid gland cholesteatoma in a 23-year-old male: case report","volume":"5","author":"Piersiala","year":"2017","journal-title":"SAGE Open Med Case Rep"}],"container-title":["Seminars in Diagnostic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0740257025000760?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0740257025000760?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T02:46:14Z","timestamp":1751424374000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0740257025000760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S0740257025000760"],"URL":"https:\/\/doi.org\/10.1016\/j.semdp.2025.150940","relation":{},"ISSN":["0740-2570"],"issn-type":[{"value":"0740-2570","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Keratocystoma: Molecular insights and diagnostic challenges in a rare salivary gland tumor","name":"articletitle","label":"Article Title"},{"value":"Seminars in Diagnostic Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semdp.2025.150940","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"150940"}}