{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T14:05:06Z","timestamp":1698761106201},"reference-count":53,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Nephrology"],"published-print":{"date-parts":[[2006,7]]},"DOI":"10.1016\/j.semnephrol.2006.05.007","type":"journal-article","created":{"date-parts":[[2006,11,28]],"date-time":"2006-11-28T00:01:06Z","timestamp":1164672066000},"page":"307-312","source":"Crossref","is-referenced-by-count":16,"title":["Anemia, Renal Transplantation, and the Anemia Paradox"],"prefix":"10.1016","volume":"26","author":[{"given":"Claudio","family":"Rigatto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.semnephrol.2006.05.007_bib1","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1034\/j.1600-6143.2003.00133.x","article-title":"Prevalence and management of anemia in renal transplant recipients: A European survey","volume":"3","author":"Vanrenterghem","year":"2003","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib2","doi-asserted-by":"crossref","first-page":"3821","DOI":"10.1016\/j.transproceed.2005.10.054","article-title":"Prevalence of anemia in renal transplant patients: Results from MOST, an observational trial","volume":"37","author":"Ferna\u00ecndez Fresnedo","year":"2005","journal-title":"Transplant Proc"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib3","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1111\/j.1399-0012.2005.00428.x","article-title":"Anemia in kidney transplanted patients","volume":"19","author":"Molnar","year":"2005","journal-title":"Clin Transplant"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib4","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1681\/ASN.V133794","article-title":"Anemia and iron deficiencies among long-term renal transplant recipients","volume":"13","author":"Lorenz","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib5","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1097\/01.ASN.0000125551.59739.2E","article-title":"Pharmacoepidemiology of anemia in kidney transplant recipients","volume":"15","author":"Winkelmayer","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib6","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1046\/j.1600-6135.2003.00224.x","article-title":"Anemia: A continuing problem following kidney transplantation","volume":"3","author":"Mix","year":"2003","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib7","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1136\/hrt.70.4.357","article-title":"Pathogenesis of oedema in chronic severe anaemia: Studies of body water and sodium, renal function, haemodynamic variables, and plasma hormones","volume":"70","author":"Anand","year":"1993","journal-title":"Br Heart J"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib8","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/S1073-4449(97)70029-3","article-title":"Cardiac disease in chronic uremia: Pathogenesis","volume":"4","author":"London","year":"1997","journal-title":"Adv Ren Replace Ther"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib9","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1172\/JCI108079","article-title":"Wall stress and patterns of hypertrophy in the human left ventricle","volume":"56","author":"Grossman","year":"1975","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib10","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/0002-9343(80)90471-4","article-title":"Cardiac hypertrophy: Useful adaptation or pathological process?","volume":"69","author":"Grossman","year":"1980","journal-title":"Am J Med"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib11","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/S1073-4449(97)70030-X","article-title":"Cardiac disease in chronic uremia: Pathophysiology","volume":"4","author":"Amann","year":"1997","journal-title":"Adv Ren Replace Ther"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib12","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1172\/JCI118280","article-title":"Stretch induced programmed myocyte death","volume":"96","author":"Cheng","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib13","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1046\/j.1525-139X.1999.00010.x","article-title":"Oxidative stress in uremia: Impact on cardiac disease in dialysis patients","volume":"12","author":"Rigatto","year":"1999","journal-title":"Semin Dial"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib14","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1159\/000168817","article-title":"Prevention of cardiac hypertrophy in experimental chronic renal failure by long term ACE inhibitor administration: Potential role of lysosomal proteinases","volume":"15","author":"Suzuki","year":"1995","journal-title":"Am J Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib15","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1681\/ASN.V4101814","article-title":"The role of parathyroid hormone in the genesis of interstitial cell activation in uremia","volume":"4","author":"Amann","year":"1994","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib16","doi-asserted-by":"crossref","first-page":"S85","DOI":"10.1111\/j.1365-2362.2005.01534.x","article-title":"Arterial structural and functional alterations in uraemia","volume":"35","author":"Gue\u00ecrin","year":"2005","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib17","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1097\/01.TP.0000090344.61975.F0","article-title":"Oxidative stress in kidney transplant patients","volume":"76","author":"Campise","year":"2003","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib18","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1161\/01.RES.55.1.120","article-title":"Differential sensitivity of canine cardiac sarcolemmal and microsomal enzymes to inhibition by free radical induced lipid peroxidation","volume":"55","author":"Kramer","year":"1984","journal-title":"Circ Res"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib19","doi-asserted-by":"crossref","first-page":"4948","DOI":"10.1016\/S0021-9258(19)89197-4","article-title":"Redox modification of sodium-calcium exchange activity in cardiac sarcolemmal vesicles","volume":"201","author":"Reeves","year":"1986","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib20","first-page":"H1280","article-title":"Antioxidant changes in hypertrophied and failing guinea pig hearts","volume":"266","author":"Dhalla","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib21","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/0735-1097(96)00140-4","article-title":"Role of oxidative stress in transition of hypertrophy to heart failure","volume":"28","author":"Dhalla","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF00219315","article-title":"Effect of lipid peroxidation on heart mitochondria oxygen consuming and calcium transporting capacities","volume":"81","author":"Ceconi","year":"1988","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib23","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1432-1033.1978.tb12615.x","article-title":"Influence of mitochondrial radical formation on energy linked respiration","volume":"90","author":"Nohl","year":"1978","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib24","first-page":"91","article-title":"Atherosclerosis: Its pathophysiology with special reference to lipid peroxidation","volume":"6","author":"Chakravarti","year":"1991","journal-title":"J Appl Cardiol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0891-5849(96)00271-7","article-title":"Antioxidants inhibit the expression of ICAM-1 and VCAM-1 induced by oxidized LDL on human umbilical vein endothelial cells","volume":"22","author":"Cominacini","year":"1997","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib26","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1161\/01.ATV.17.3.445","article-title":"Oxidized LDL mediates the release of FGF-1","volume":"17","author":"Ananyeva","year":"1997","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib27","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/ncpcardio0094","article-title":"Therapy insight: congestive heart failure, chronic kidney disease and anemia, the cardio-renal-anemia syndrome","volume":"2","author":"Iaina","year":"2005","journal-title":"Nat Clin Pract Cardiovasc Med"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib28","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ccc.2004.01.001","article-title":"Physiologic aspects of anemia","volume":"20","author":"Hebert","year":"2004","journal-title":"Crit Care Clin"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib29","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1093\/cvr\/23.10.842","article-title":"Circulatory effects of acute normovolaemic haemodilution in rats with healed myocardial infarction","volume":"23","author":"Kobayashi","year":"1989","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib30","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1016\/S0735-1097(01)01248-7","article-title":"The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: A randomized controlled study","volume":"37","author":"Silverberg","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib31","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1159\/000185077","article-title":"Analysis of left ventricular changes associated with chronic hemodialysis: A non-invasive follow-up study","volume":"49","author":"Huting","year":"1988","journal-title":"Nephron"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib32","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1159\/000185937","article-title":"The clinical course of left ventricular hypertrophy in dialysis patients","volume":"55","author":"Parfrey","year":"1990","journal-title":"Nephron"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib33","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0272-6386(96)90130-4","article-title":"The impact of anemia on cardiomyopathy, morbidity and mortality in end stage renal disease","volume":"28","author":"Foley","year":"1996","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib34","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0272-6386(99)70118-6","article-title":"Left ventricular mass index increase in early renal disease: Impact of decline in hemoglobin","volume":"34","author":"Levin","year":"1999","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib35","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1093\/ndt\/11.7.1277","article-title":"The outcome and risk factors for left ventricular disorders in chronic uremia","volume":"11","author":"Parfrey","year":"1996","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib36","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1046\/j.1523-1755.1998.00154.x","article-title":"The long term evolution of cardiomyopathy in dialysis patients","volume":"54","author":"Foley","year":"1998","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib37","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1111\/j.1523-1755.2005.00693.x","article-title":"Anemia and mortality in hemodialysis patients: Accounting for morbidity and treatment variables updated over time","volume":"68","author":"Robinson","year":"2005","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib38","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0272-6386(12)80453-7","article-title":"Long term myocardial effects of correction of anemia with recombinant human erythropoietin in aged dialysis patients","volume":"14","author":"Martinez-Vea","year":"1992","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib39","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1038\/ki.1993.383","article-title":"Cardiovascular consequences of the correction of anemia of renal failure with erythropoietin","volume":"44","author":"Fellner","year":"1993","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib40","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1046\/j.1523-1755.2003.00109.x","article-title":"Chronic kidney disease, anemia, and incident stroke in a middle-aged, community-based population: The ARIC study","volume":"64","author":"Abramson","year":"2003","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib41","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.ahj.2005.03.055","article-title":"Kidney function and anemia as risk factors for coronary heart disease and mortality: The Atherosclerosis Risk in Communities (ARIC) study","volume":"151","author":"Astor","year":"2006","journal-title":"Am Heart J"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib42","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1681\/ASN.V1341084","article-title":"Congestive heart failure in renal transplant recipients: Risk factors, outcomes, and relationship with ischemic heart disease","volume":"13","author":"Rigatto","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib43","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1097\/01.ASN.0000043141.67989.39","article-title":"Electrocardiographic left ventricular hypertrophy in renal transplant recipients: Prognostic value and impact of blood pressure and anemia","volume":"14","author":"Rigatto","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib44","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1097\/01.TP.0000084872.26360.C5","article-title":"Increasing hematocrit reduces early posttransplant cardiovascular risk in diabetic transplant recipients","volume":"76","author":"Djamali","year":"2003","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib45","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1136\/bmj.300.6724.573","article-title":"Association between recombinant human erythropoietin and quality of life and exercise capacity of patients receiving haemodialysis","volume":"300","year":"1990","journal-title":"BMJ"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib46","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1159\/000419519","article-title":"Morbidity and mortality in hemodialysis patients with and without erythropoietin treatment: A controlled study","volume":"88","author":"Bahlmann","year":"1991","journal-title":"Contrib Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib47","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1525-1594.1993.tb00571.x","article-title":"Adverse events of subcutaneous recombinant human erythropoietin therapy: Results of a controlled multicenter European study","volume":"17","author":"Klinkmann","year":"1993","journal-title":"Artif Organs"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib48","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1053\/j.ajkd.2005.09.007","article-title":"Evidence-based systematic literature review of hemoglobin\/hematocrit and all-cause mortality in dialysis patients","volume":"47","author":"Volkova","year":"2006","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib49","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/j.1523-1755.2004.00797.x","article-title":"Treating anemia early in renal failure patients slows the decline of renal function: A randomized controlled trial","volume":"66","author":"Gouva","year":"2004","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib50","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1056\/NEJM199808273390903","article-title":"The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin","volume":"339","author":"Besarab","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib51","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1681\/ASN.2004121039","article-title":"Double-blind comparison of full and partial anemia correction in incident hemodialysis patients without symptomatic heart disease","volume":"16","author":"Parfrey","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.05.007_bib52","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1053\/j.ajkd.2005.08.007","article-title":"Canadian randomized trial of hemoglobin maintenance to prevent or delay left ventricular mass growth in patients with CKD","volume":"46","author":"Levin","year":"2005","journal-title":"Am J Kidney Dis"},{"issue":"suppl 4","key":"10.1016\/j.semnephrol.2006.05.007_bib53","first-page":"48","article-title":"Long-term management of the transplant recipient","volume":"17","year":"2002","journal-title":"Anaemia Nephrol Dial Transplant"}],"container-title":["Seminars in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929506000738?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929506000738?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T05:14:01Z","timestamp":1628140441000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0270929506000738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7]]},"references-count":53,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006,7]]}},"alternative-id":["S0270929506000738"],"URL":"https:\/\/doi.org\/10.1016\/j.semnephrol.2006.05.007","relation":{},"ISSN":["0270-9295"],"issn-type":[{"value":"0270-9295","type":"print"}],"subject":[],"published":{"date-parts":[[2006,7]]}}}