{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T21:38:12Z","timestamp":1778276292830,"version":"3.51.4"},"reference-count":140,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Nephrology"],"published-print":{"date-parts":[[2006,9]]},"DOI":"10.1016\/j.semnephrol.2006.07.004","type":"journal-article","created":{"date-parts":[[2006,11,28]],"date-time":"2006-11-28T00:01:34Z","timestamp":1164672094000},"page":"361-374","source":"Crossref","is-referenced-by-count":20,"title":["Kidney Vacuolar H+-ATPase: Physiology and Regulation"],"prefix":"10.1016","volume":"26","author":[{"given":"Patricia","family":"Valles","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S.","family":"Lapointe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Wysocki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Batlle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.semnephrol.2006.07.004_bib1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/nrm729","article-title":"The vacuolar (H+)-ATPases-nature\u2019s most versatile proton pumps","volume":"3","author":"Nishi","year":"2002","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib2","doi-asserted-by":"crossref","first-page":"12951","DOI":"10.1074\/jbc.274.19.12951","article-title":"Structure and properties of the vacuolar (H+)-ATPases","volume":"274","author":"Forgac","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib3","series-title":"The Kidney; Physiology and Pathophysiology","first-page":"171","article-title":"Structure, function, and cellular distribution of the vacuolar H+-ATPase (HV ATPase\/proton pump)","author":"Brown","year":"2000"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib4","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/BF00762532","article-title":"Genetic and cell biological aspects of the yeast vacuolar H(+)-ATPase","volume":"24","author":"Anraku","year":"1992","journal-title":"J Bioenerg Biomembr"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1242\/jeb.203.1.71","article-title":"Structure, mechanism and regulation of the clathrin-coated vesicle and yeast vacuolar H+-ATPases","volume":"203","author":"Forgac","year":"2000","journal-title":"J Exp Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib6","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1002\/jcp.1041570304","article-title":"Relative roles of Na+\/H+ exchange and vacuolar-type H+ ATPases in regulating cytoplasmic pH and function in murine peritoneal macrophages","volume":"157","author":"Swallow","year":"1993","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib7","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/BF00762528","article-title":"The structure and biochemistry of the vacuolar H+-ATPase in proximal and distal urinary acidification","volume":"24","author":"Gluck","year":"1992","journal-title":"J Bioenerg Biomembr"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib8","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1126\/science.1080106","article-title":"Activation of lysosomal function during dendritic cell maturation","volume":"299","author":"Trombetta","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib9","first-page":"R1695","article-title":"Effect of locally applied drugs on the pH of luminal fluid in the endolymphatic sac of guinea pig","volume":"279","author":"Couloigner","year":"2000","journal-title":"Am J Physiol"},{"issue":"suppl","key":"10.1016\/j.semnephrol.2006.07.004_bib10","first-page":"S98","article-title":"Mechanisms of endolymph secretion","volume":"53","author":"Ferrary","year":"1998","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0378-5955(97)00072-5","article-title":"Localization of pH regulating proteins H+-ATPase and Cl\u2212\/HCO3\u2212 exchanger in guinea pig inner ear","volume":"114","author":"Stankovic","year":"1997","journal-title":"Hear Res"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib12","doi-asserted-by":"crossref","first-page":"C1134","DOI":"10.1152\/ajpcell.1998.275.4.C1134","article-title":"Proton secretion in the male reproductive tract: Involvement of Cl\u2212-independent HCO3\u2212 transport","volume":"275","author":"Breton","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib13","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1007\/s000180300040","article-title":"ATP synthases","volume":"60","author":"Muller","year":"2003","journal-title":"Cell Mol Life Sci"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib14","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1242\/jeb.204.15.2597","article-title":"Structure-function relationships of A-, F- and V-ATPases","volume":"204","author":"Gruber","year":"2001","journal-title":"J Exp Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib15","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1152\/physrev.00045.2003","article-title":"Renal vacuolar H+-ATPase","volume":"84","author":"Wagner","year":"2004","journal-title":"Physiol Rev"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib16","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1152\/physrev.1999.79.2.361","article-title":"Vacuolar and plasma membrane proton adenosine-triphosphatases","volume":"79","author":"Nelson","year":"1999","journal-title":"Physiol Rev"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib17","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/S1097-2765(03)00397-6","article-title":"Revised nomenclature for mammalian vacuolar-type H+-ATPase subunit genes","volume":"12","author":"Smith","year":"2003","journal-title":"Mol Cell"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib18","series-title":"The Mycota III","first-page":"57","article-title":"Biochemistry and Molecular Biology","author":"Bowman","year":"1996"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib19","doi-asserted-by":"crossref","first-page":"11750","DOI":"10.1074\/jbc.272.18.11750","article-title":"Site-directed mutagenesis of the yeast V-ATPase A subunit","volume":"272","author":"Liu","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib20","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1074\/jbc.273.1.150","article-title":"Mutational analysis of the nucleotide binding sites of the yeast vacuolar proton-translocating ATPase","volume":"273","author":"MacLeod","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib21","doi-asserted-by":"crossref","first-page":"12775","DOI":"10.1074\/jbc.271.22.12775","article-title":"3\u2032-O-(4-Benzoyl)benzoyladenosine 5\u2032-triphosphate inhibits activity of the vacuolar (H+)-ATPase from bovine brain clathrin-coated vesicles by modification of a rapidly exchangeable, noncatalytic nucleotide binding site on the B subunit","volume":"271","author":"Vasilyeva","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib22","doi-asserted-by":"crossref","first-page":"15780","DOI":"10.1016\/S0021-9258(18)47797-6","article-title":"Immunoaffinity purification and characterization of vacuolar H+ATPase from bovine kidney","volume":"262","author":"Gluck","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib23","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1042\/bj3030191","article-title":"Heterogeneity of vacuolar H+-ATPase differential expression of two human subunit B isoforms","volume":"303","author":"Van Hille","year":"1994","journal-title":"Biochem J"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib24","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.1073\/pnas.89.8.3541","article-title":"Selectively amplified expression of an isoform of the vacuolar H+-ATPase 56-kilodalton subunit in renal intercalated cells","volume":"89","author":"Nelson","year":"1992","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib25","doi-asserted-by":"crossref","first-page":"18219","DOI":"10.1074\/jbc.M909857199","article-title":"The B1 subunit of the H+ATPase is a PDZ domain-binding protein","volume":"275","author":"Breton","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib26","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1136\/jmg.39.11.796","article-title":"Novel ATP6V1B1 and ATP6V0A4 mutations in autosomal recessive distal renal tubular acidosis with new evidence for hearing loss","volume":"39","author":"Stover","year":"2002","journal-title":"J Med Genet"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib27","doi-asserted-by":"crossref","first-page":"22570","DOI":"10.1074\/jbc.273.35.22570","article-title":"Multiple genes for vacuolar-type ATPase proteolipids in Caenorhabditis elegans","volume":"273","author":"Oka","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib28","doi-asserted-by":"crossref","first-page":"7972","DOI":"10.1073\/pnas.85.21.7972","article-title":"Bafilomycins a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells","volume":"85","author":"Bowman","year":"1988","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib29","doi-asserted-by":"crossref","first-page":"3965","DOI":"10.1074\/jbc.M109756200","article-title":"Mutations in subunit c of the vacuolar ATPase confer resistance to bafilomycin and identify a conserved antibiotic binding site","volume":"277","author":"Bowman","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib30","doi-asserted-by":"crossref","first-page":"17379","DOI":"10.1016\/S0021-9258(17)32447-X","article-title":"Bafilomycin inhibits proton flow through the H+ channel of vacuolar proton pumps","volume":"269","author":"Crider","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib31","doi-asserted-by":"crossref","first-page":"40481","DOI":"10.1074\/jbc.M509106200","article-title":"Subunit a of the yeast V-ATPase participates in binding of bafilomycin","volume":"280","author":"Wang","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib32","doi-asserted-by":"crossref","first-page":"4795","DOI":"10.1074\/jbc.272.8.4795","article-title":"VMA11 and VMA16 encode second and third proteolipid subunits of the Saccharomyces cerevisiae vacuolar membrane H+-ATPase","volume":"272","author":"Hirata","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib33","doi-asserted-by":"crossref","first-page":"17941","DOI":"10.1074\/jbc.M010790200","article-title":"Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociation","volume":"276","author":"Kawasaki-Nishi","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib34","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/82492","article-title":"Mutations in ATP6N1B, encoding a new kidney vacuolar proton pump 116-kD subunit, cause recessive distal renal tubular acidosis with preserved hearing","volume":"26","author":"Smith","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib35","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/77131","article-title":"Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosis","volume":"25","author":"Frattini","year":"2000","journal-title":"Nat Genet"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib36","doi-asserted-by":"crossref","first-page":"42382","DOI":"10.1074\/jbc.M107267200","article-title":"Molecular cloning and characterization of Atp6n1b a novel fourth murine vacuolar H+-ATPase a-subunit gene","volume":"276","author":"Smith","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib37","doi-asserted-by":"crossref","first-page":"14655","DOI":"10.1074\/jbc.274.21.14655","article-title":"Transmembrane topography of the 100-kDa a subunit (Vph1p) of the yeast vacuolar proton-translocating ATPase","volume":"274","author":"Leng","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib38","doi-asserted-by":"crossref","first-page":"6824","DOI":"10.1074\/jbc.275.10.6824","article-title":"Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase","volume":"275","author":"Nishi","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib39","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0378-1119(02)00884-3","article-title":"Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C","volume":"297","author":"Smith","year":"2002","journal-title":"Gene"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib40","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1681\/ASN.2004090761","article-title":"Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and bone","volume":"5","author":"Smith","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib41","doi-asserted-by":"crossref","first-page":"46396","DOI":"10.1074\/jbc.M303924200","article-title":"Expression and function of the mouse V-ATPase d subunit isoforms","volume":"278","author":"Nishi","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib42","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1038\/29908","article-title":"ATP synthase\u2019s second stalk comes into focus","volume":"393","author":"Wilkens","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib43","doi-asserted-by":"crossref","first-page":"31804","DOI":"10.1074\/jbc.274.45.31804","article-title":"Structure of the vacuolar ATPase by electron microscopy","volume":"274","author":"Wilkens","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib44","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1073\/pnas.0436796100","article-title":"Evidence for rotation of V1-ATPase","volume":"100","author":"Imamura","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib45","doi-asserted-by":"crossref","first-page":"23714","DOI":"10.1074\/jbc.M302756200","article-title":"Subunit rotation of vacuolar-type proton pumping ATPase relative rotation of the G and C subunits","volume":"278","author":"Hirata","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib46","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1073\/pnas.0305165101","article-title":"Crystal structure of a central stalk subunit C and reversible association\/dissociation of vacuole-type ATPase","volume":"101","author":"Iwata","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib47","doi-asserted-by":"crossref","first-page":"8979","DOI":"10.1074\/jbc.M111708200","article-title":"Mutational analysis of the subunit C (Vma5p) of the yeast vacuolar H+-ATPase","volume":"277","author":"Curtis","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib48","doi-asserted-by":"crossref","first-page":"17025","DOI":"10.1016\/S0021-9258(17)46944-4","article-title":"Disassembly and reassembly of the yeast vacuolar H(+)-ATPase in vivo","volume":"270","author":"Kane","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib49","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.1074\/jbc.270.10.5649","article-title":"Regulation of plasma membrane V-ATPase activity by dissociation of peripheral subunits","volume":"270","author":"Sumner","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib50","doi-asserted-by":"crossref","first-page":"27896","DOI":"10.1074\/jbc.M504890200","article-title":"Cysteine-mediated cross-linking indicates that subunit C of the V-ATPase is in close proximity to subunits E and G of the V1 domain and subunit a of the Vo domain","volume":"280","author":"Inoue","year":"1995","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib51","doi-asserted-by":"crossref","first-page":"15449","DOI":"10.1074\/jbc.M000207200","article-title":"Evidence that the NH2 terminus of vph1p, an integral subunit of the V0 sector of the yeast V-ATPase, interacts directly with the Vma1p and Vma13p subunits of the V1 sector","volume":"275","author":"Landolt-Marticorena","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib52","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1046\/j.1432-1327.1999.00396.x","article-title":"Biosynthesis of the vacuolar H+-ATPase accessory subunit Ac45 in Xenopus pituitary","volume":"262","author":"Holthuis","year":"1999","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib53","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.1681\/ASN.2004110935","article-title":"Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis","volume":"16","author":"Jouret","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib54","series-title":"The Kidney Physiology and Pathophysiology","first-page":"1935","article-title":"Cellular mechanisms of renal tubular acidification","author":"Hamm","year":"2000"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib55","first-page":"S64","article-title":"Biochemical aspects of H+-ATPase in renal proximal tubules: Inhibition by N, N\u2032-dicyclohexylcarbodiimide, N-ethylmaleimide, and bafilomycin","volume":"33","author":"Jehmlich","year":"1991","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib56","first-page":"F817","article-title":"Characteristics of the proton pump in rat renal cortical endocytotic vesicles","volume":"250","author":"Sabolic","year":"1986","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib57","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1172\/JCI113833","article-title":"Localization of a proton-pumping ATPase in rat kidney","volume":"82","author":"Brown","year":"1988","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib58","doi-asserted-by":"crossref","first-page":"C149","DOI":"10.1152\/ajpcell.00464.2003","article-title":"Expression of the 56-kDa B2 subunit isoform of the vacuolar H(+)-ATPase in proton-secreting cells of the kidney and epididymis","volume":"287","author":"Paunescu","year":"2004","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib59","doi-asserted-by":"crossref","first-page":"9948","DOI":"10.1016\/S0021-9258(19)50184-3","article-title":"Immunologic evidence that vacuolar H+ ATPases with heterogeneous forms of Mr = 31,000 subunit have different membrane distributions in mammalian kidney","volume":"267","author":"Hemken","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib60","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1172\/JCI9260","article-title":"Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule","volume":"105","author":"Choi","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib61","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1046\/j.1523-1755.2002.00681.x","article-title":"Bicarbonate reabsorption and NHE-3 expression abundance and activity are increased in Henle\u2019s loop of remnant rats","volume":"62","author":"Capasso","year":"2002","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib62","first-page":"F601","article-title":"Immunolocalization of AE2 anion exchanger in rat kidney","volume":"273","author":"Alper","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib63","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1172\/JCI115268","article-title":"Expression and distribution of renal vacuolar proton-translocating adenosine triphosphatase in response to chronic acid and alkali loads in the rat","volume":"88","author":"Bastani","year":"1991","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib64","doi-asserted-by":"crossref","first-page":"5429","DOI":"10.1073\/pnas.86.14.5429","article-title":"Subtypes of intercalated cells in rat kidney collecting duct defined by antibodies against erythroid band 3 and renal vacuolar H+-ATPase","volume":"86","author":"Alper","year":"1989","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib65","first-page":"F229","article-title":"Localization of pendrin in mouse kidney","volume":"284","author":"Wall","year":"2002","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib66","doi-asserted-by":"crossref","first-page":"8180","DOI":"10.1074\/jbc.M004513200","article-title":"A new member of the HCO3\u2212 transporter superfamily is an apical anion exchanger of beta-intercalated cells in the kidney","volume":"276","author":"Tsuganezawa","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib67","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1146\/annurev.physiol.64.092801.141759","article-title":"Genetic diseases of acid-base transporters","volume":"64","author":"Alper","year":"2002","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib68","first-page":"F584","article-title":"Regulated expression of pendrin in rat kidney in response to chronic NH4Cl or NaHCO3 loading","volume":"284","author":"Frische","year":"2003","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib69","first-page":"F635","article-title":"Transport characteristics of the apical anion exchanger of rabbit cortical collecting duct beta-cells","volume":"276","author":"Emmons","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib70","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1046\/j.1523-1755.2002.00671.x","article-title":"Regulation of the expression of the Cl\u2212\/anion exchanger pendrin in mouse kidney by acid-base status","volume":"62","author":"Wagner","year":"2002","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib71","doi-asserted-by":"crossref","first-page":"4221","DOI":"10.1073\/pnas.071516798","article-title":"Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion","volume":"98","author":"Royaux","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib72","first-page":"E25","article-title":"Prolactin regulation of the pendrin-iodide transporter in the mammary gland","volume":"284","author":"Rillema","year":"2003","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib73","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1097\/01.mnh.0000168390.04520.06","article-title":"Recent advances in our understanding of intercalated cells","volume":"14","author":"Wall","year":"2005","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib74","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1681\/ASN.V134827","article-title":"Contribution of the Na+-K+-2 CL\u2212cotransporter (NKCC1) to transepithelial transport of H+, NH4+, K+, and Na+ in rat outer medullary collecting duct","volume":"13","author":"Wall","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib75","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1097\/01.ASN.0000135060.83250.07","article-title":"Differential regulation of basolateral Cl\u2212\/HCO3\u2212 exchangers Slc26a7 and AE1 in kidney outer medullary collecting duct","volume":"15","author":"Barone","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib76","first-page":"F595","article-title":"Roles and mechanisms of urinary buffer excretion","volume":"253","author":"Hamm","year":"1987","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib77","first-page":"F450","article-title":"Luminal acidification in K-replete OMCDi: contributions of H+-K+-ATPase and bafilomycin-A1-sensitive H-ATPase","volume":"267","author":"Armitage","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib78","first-page":"219","article-title":"Morphologic heterogeneity along the rat inner medullary collecting duct","volume":"60","author":"Clapp","year":"1989","journal-title":"Lab Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib79","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0005-2736(96)00123-X","article-title":"Proton gradient formation in early endosomes from proximal tubules","volume":"1284","author":"Marshansky","year":"1996","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib80","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF00233457","article-title":"H+ extrusion by an apical vacuolar-type H+-ATPase in rat renal proximal tubules","volume":"126","author":"Zimolo","year":"1992","journal-title":"J Membr Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib81","doi-asserted-by":"crossref","first-page":"9665","DOI":"10.1073\/pnas.95.16.9665","article-title":"Angiotensin II stimulates vesicular H+-ATPase in rat proximal tubular cells","volume":"95","author":"Wagner","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib82","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s002320010019","article-title":"Cell pH and H+ secretion by S3 segment of mammalian kidney role of H+-ATPase and Cl\u2212","volume":"178","author":"Malnic","year":"2000","journal-title":"J Membr Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib83","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s002329900228","article-title":"Role of Cl\u2212 in electrogenic H+ secretion by cortical distal tubule","volume":"157","author":"Fernandez","year":"1997","journal-title":"J Membr Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib84","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1007\/s004240050438","article-title":"The intrinsic Cl\u2212 conductance of mouse kidney cortex brush-border membrane vesicles is not related to CFTR","volume":"434","author":"King","year":"1997","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib85","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1432-1033.1997.00367.x","article-title":"Properties of chloride-conductive pathways in rat kidney cortical and outer-medulla brush-border membranes\u2014inhibition by anti-(cystic fibrosis transmembrane regulator) mAbs","volume":"246","author":"Benharouga","year":"1997","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib86","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/348637a0","article-title":"Protein kinase A regulates chloride conductance in endocytic vesicles from proximal tubule","volume":"348","author":"Bae","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib87","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/S0092-8674(00)80654-6","article-title":"Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors","volume":"96","author":"Bremser","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib88","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1083\/jcb.133.1.29","article-title":"An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes","volume":"133","author":"Aniento","year":"1996","journal-title":"J Cell Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib89","first-page":"F55","article-title":"Assembly of distinctive coated pit and microvillar microdomains in the renal brush border","volume":"262","author":"Biemesderfer","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib90","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1038\/35052017","article-title":"SNARE-mediated membrane fusion","volume":"2","author":"Chen","year":"2001","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib91","doi-asserted-by":"crossref","first-page":"15781","DOI":"10.1073\/pnas.95.26.15781","article-title":"Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as q- and r-SNAREs","volume":"95","author":"Fasshauer","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib92","doi-asserted-by":"crossref","first-page":"26518","DOI":"10.1074\/jbc.274.37.26518","article-title":"SNARE proteins regulate H+-ATPase redistribution to the apical membrane in rat renal inner medullary collecting duct cells","volume":"274","author":"Banerjee","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib93","doi-asserted-by":"crossref","first-page":"19791","DOI":"10.1074\/jbc.M212250200","article-title":"Syntaxin isoform specificity in the regulation of renal H+-ATPase exocytosis","volume":"278","author":"Li","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib94","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1083\/jcb.200212004","article-title":"Vacuole membrane fusion: V0 functions after trans-SNARE pairing and is coupled to the Ca2+-releasing channel","volume":"162","author":"Bayer","year":"2003","journal-title":"J Cell Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib95","doi-asserted-by":"crossref","first-page":"3541","DOI":"10.1073\/pnas.89.8.3541","article-title":"Selectively amplified expression of an isoform of the vacuolar H+-ATPase 56-kilodalton subunit in renal intercalated cells","volume":"89","author":"Nelson","year":"1992","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib96","doi-asserted-by":"crossref","first-page":"3696","DOI":"10.1016\/S0021-9258(19)50581-6","article-title":"Differential expression of the \u201cB\u201d subunit of the vacuolar H+-ATPase in bovine tissues","volume":"267","author":"Puopolo","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib97","doi-asserted-by":"crossref","first-page":"C667","DOI":"10.1152\/ajpcell.00225.2002","article-title":"The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction","volume":"284","author":"Pushkin","year":"2003","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib98","doi-asserted-by":"crossref","first-page":"18499","DOI":"10.1074\/jbc.M212844200","article-title":"A novel role for subunit C in mediating binding of the H+-V-ATPase to the actin cytoskeleton","volume":"278","author":"Vitavska","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib99","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/318368a0","article-title":"Plasticity of functional epithelial polarity","volume":"318","author":"Schwartz","year":"1985","journal-title":"Nature"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib100","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1172\/JCI0213292","article-title":"Acid incubation reverses the polarity of intercalated cell transporters, an effect mediated by hensin","volume":"109","author":"Schwartz","year":"2002","journal-title":"Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib101","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1172\/JCI119044","article-title":"Hensin, a new collecting duct protein involved in the in vitro plasticity of intercalated cell polarity","volume":"98","author":"Takito","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib102","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/01.mnh.0000172727.82993.aa","article-title":"Role of hensin in mediating the adaptation of the cortical collecting duct to metabolic acidosis","volume":"14","author":"Schwartz","year":"2005","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib103","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1172\/JCI0213292","article-title":"Acid incubation reverses the polarity of intercalated cell transporters, an effect mediated by hensin","volume":"109","author":"Schwartz","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib104","first-page":"F148","article-title":"Galectin-3 expression is induced in renal beta-intercalated cells during metabolic acidosis","volume":"290","author":"Schwaderer","year":"2006","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib105","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1083\/jcb.109.3.1279","article-title":"Cellular remodeling of HCO3\u2212-secreting cells in rabbit renal collecting duct in response to an acidic environment","volume":"109","author":"Satlin","year":"1989","journal-title":"J Cell Biol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib106","first-page":"F390","article-title":"Effect of respiratory acidosis and respiratory alkalosis on renal transport enzymes","volume":"267","author":"Eiam-ong","year":"1994","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib107","first-page":"F259","article-title":"Carbonic anhydrase II and IV mRNA in rabbit nephron segments: Stimulation during metabolic acidosis","volume":"274","author":"Tsuruoka","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib108","first-page":"S79","article-title":"Colchicine-induced redistribution of proton pumps in kidney epithelial cells","volume":"33","author":"Brown","year":"1991","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib109","first-page":"F583","article-title":"Effect of metabolic acidosis and alkalosis on NEM-sensitive ATPase in rat nephron segments","volume":"262","author":"Khadouri","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib110","first-page":"F532","article-title":"Potassium deprivation upregulates expression of renal basolateral Na+-HCO3\u2212 cotransporter (NBC-1)","volume":"279","author":"Amlal","year":"2000","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib111","first-page":"F656","article-title":"Morphometric analysis of kidney hypertrophy in rats after chronic potassium depletion","volume":"262","author":"Elger","year":"1992","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib112","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1093\/ndt\/14.6.1435","article-title":"The relationship between distal tubular proton secretion and dietary potassium depletion: Evidence for up-regulation of H+-ATPase","volume":"14","author":"Bailey","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib113","doi-asserted-by":"crossref","first-page":"31S","DOI":"10.1016\/S0895-7061(99)00249-6","article-title":"Localization and function of angiotensin AT1 receptors","volume":"13","author":"Allen","year":"2000","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib114","first-page":"F1147","article-title":"Immortalized rabbit cortical collecting duct cells express AT1 angiotensin II receptors","volume":"271","author":"Burns","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib115","first-page":"S189","article-title":"Concentrations and actions of intraluminal angiotensin II","volume":"10","author":"Navar","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib116","first-page":"F143","article-title":"Effects of angiotensin II on electrolyte transport in the early and late distal tubule in rat kidney","volume":"271","author":"Wang","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib117","first-page":"A0054","article-title":"Stimulation of H+-ATPase in intercalated cells from isolated mouse cortical collecting ducts by angiotensin II","volume":"11","author":"Wagner","year":"2000","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib118","first-page":"F476","article-title":"Surviving rat distal tubule bicarbonate reabsorption: Effects of chronic AT1 blockade","volume":"278","author":"Levine","year":"2000","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib119","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1681\/ASN.V8111658","article-title":"Expression of type 1 angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron","volume":"8","author":"Bouby","year":"1997","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib120","first-page":"F730","article-title":"Regulation of luminal alkalinization and acidification in the cortical collecting duct by angiotensin II","volume":"269","author":"Weiner","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib121","first-page":"S112","article-title":"Acid-base transport in the collecting duct","volume":"15","author":"Wagner","year":"2002","journal-title":"J Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib122","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1161\/01.HYP.0000154787.42718.a4","article-title":"Angiotensin II increases H+-ATPase B1 subunit expression in medullary collecting ducts","volume":"45","author":"Vall\u00e9s","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib123","first-page":"F576","article-title":"Mineralocorticoid effects on cation transport by cortical collecting tubules in vitro","volume":"235","author":"Schwartz","year":"1978","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib124","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1172\/JCI110986","article-title":"Mineralocorticoid modulation of rabbit medullary collecting duct acidification","volume":"72","author":"Stone","year":"1983","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib125","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/ki.1988.139","article-title":"Effects of aldosterone on NEM-sensitive ATPase in rabbit nephron segments","volume":"34","author":"Garg","year":"1988","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib126","first-page":"F319","article-title":"Early aldosterone action: Toward filling the gap between transcription and transport","volume":"277","author":"Verrey","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib127","first-page":"68","article-title":"Aldosterone increases the synthesis and cell surface expression of a4, a kidney specific subunit of H+-ATPase in a mouse renal collecting tubule cell line","volume":"14","author":"Moorthi","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib128","article-title":"Early genomic effect of aldosterone on a4 subunit of the vacuolar H+-ATPase","volume":"16","author":"Wysocki","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib129","doi-asserted-by":"crossref","first-page":"2385","DOI":"10.1172\/JCI116471","article-title":"Regulation of collecting tubule adenosine triphosphates by aldosterone and potassium","volume":"91","author":"Eiam-Ong","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib130","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1073\/pnas.0307321101","article-title":"Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone","volume":"101","author":"Winter","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib131","series-title":"The Metabolic and Molecular Bases of Inherited Disease","first-page":"4983","article-title":"Renal tubular acidosis","author":"DuBose","year":"2001"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib132","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1097\/01.ASN.0000023430.92674.E5","article-title":"Renal tubular acidosis: the clinical entity","volume":"13","author":"Rodriguez-Soriano","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib133","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/5022","article-title":"Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness","volume":"21","author":"Karet","year":"1999","journal-title":"Nat Genet"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib134","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1086\/302679","article-title":"Localization of a gene for autosomal recessive distal renal tubular acidosis with normal hearing (rdRTA2) to 7q33-34","volume":"65","author":"Karet","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib135","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/j.1399-0004.1994.tb04022.x","article-title":"The primary hereditary form of distal renal tubular acidosis: Clinical and genetic studies in a 60-member kindred","volume":"45","author":"Chaabani","year":"1994","journal-title":"Clin Genet"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib136","doi-asserted-by":"crossref","first-page":"6337","DOI":"10.1073\/pnas.95.11.6337","article-title":"Mutations in the chloride-bicarbonate exchanger gene AE1 cause autosomal dominant but not autosomal recessive distal renal tubular acidosis","volume":"95","author":"Karet","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib137","first-page":"0015","article-title":"Generation and characterization of H+-ATPase B1 subunit deficient mice","volume":"12","author":"Finberg","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib138","first-page":"0004","article-title":"Loss of plasma membrane H+-ATPase activity from cortical collecting duct intercalated cells of H+-ATPase B1-subunit deficient mice: A mouse model of distal renal tubular acidosis","volume":"13","author":"Finberg","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib139","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S0014-5793(03)00396-X","article-title":"Proton translocation driven by ATP hydrolysis in V-ATPases","volume":"545","author":"Kawasaki-Nishi","year":"2003","journal-title":"FEBS Lett"},{"key":"10.1016\/j.semnephrol.2006.07.004_bib140","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00424-003-1082-3","article-title":"A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse","volume":"446","author":"Wagner","year":"2003","journal-title":"Pflugers Arch"}],"container-title":["Seminars in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929506000817?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929506000817?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,5]],"date-time":"2021-08-05T05:14:35Z","timestamp":1628140475000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0270929506000817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":140,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["S0270929506000817"],"URL":"https:\/\/doi.org\/10.1016\/j.semnephrol.2006.07.004","relation":{},"ISSN":["0270-9295"],"issn-type":[{"value":"0270-9295","type":"print"}],"subject":[],"published":{"date-parts":[[2006,9]]}}}