{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:03:17Z","timestamp":1791925397599,"version":"4.3.4"},"reference-count":55,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Nephrology"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.semnephrol.2011.09.008","type":"journal-article","created":{"date-parts":[[2011,11,19]],"date-time":"2011-11-19T02:41:05Z","timestamp":1321670465000},"page":"535-541","source":"Crossref","is-referenced-by-count":46,"title":["Diuretics and Disorders of Calcium Homeostasis"],"prefix":"10.1016","volume":"31","author":[{"given":"Marvin","family":"Grieff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Bushinsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semnephrol.2011.09.008_bib1","series-title":"Brenner and Rector's the kidney","first-page":"1299","article-title":"Nephrolithiasis","author":"Bushinsky","year":"2007"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib2","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s11926-006-0029-z","article-title":"Idiopathic hypercalciuria","volume":"8","author":"Leibman","year":"2006","journal-title":"Curr Rheumatol Rep"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib3","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1056\/NEJMcp1001011","article-title":"Calcium kidney stones","volume":"363","author":"Worcester","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0272-6386(85)80128-1","article-title":"Diuretics and calcium metabolism","volume":"5","author":"Sutton","year":"1985","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib5","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1172\/JCI24134","article-title":"Enhanced passive Ca2+ reabsorption and reduce Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia","volume":"115","author":"Nijenhuis","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib6","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1681\/ASN.2004070543","article-title":"Thiazides reduce brushite, but not calcium oxalate, supersaturation, and stone formation in genetic hypercalciuric stone-forming rats","volume":"16","author":"Bushinsky","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib7","unstructured":"Bushinsky DA, Willett T, Asplin JR, Grynpas MD. Chlorthalidone improves bone quality in genetic hypercalciuric stone-forming rats. Presented in abstract form at: 43rd Annual Meeting and Scientific Exposition of the American Society of Nephrology; 2010 Nov 16-21; Denver, CO."},{"key":"10.1016\/j.semnephrol.2011.09.008_bib8","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.2215\/CJN.04670510","article-title":"The evidence-based use of thiazide diuretics in hypertension and nephrolithiasis","volume":"5","author":"Reilly","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib9","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1097\/00041552-200103000-00008","article-title":"Prevention of nephrolithiasis","volume":"10","author":"Pearle","year":"2001","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib10","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1089\/end.1999.13.679","article-title":"Meta-analysis of randomized trials for medical prevention of calcium oxalate nephrolithiasis","volume":"9","author":"Pearle","year":"1999","journal-title":"J Endourol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib11","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1056\/NEJM199808063390607","article-title":"Diuretic therapy","volume":"339","author":"Brater","year":"1998","journal-title":"N Engl J Med"},{"issue":"Suppl 6","key":"10.1016\/j.semnephrol.2011.09.008_bib12","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1097\/00005344-199312050-00014","article-title":"Randomized prospective study of a nonthiazide diuretic, indapamide, in preventing stone recurrences","volume":"22","author":"Borghi","year":"1993","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib13","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.0954-6820.1984.tb05023.x","article-title":"Thiazide prophylaxis of urolithiasis","volume":"215","author":"Laerum","year":"1984","journal-title":"Acta Med Scand"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib14","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0022-5347(17)42599-7","article-title":"Chlorthalidone reduces calcium oxalate calculous recurrence but magnesium hydroxide does not","volume":"139","author":"Ettinger","year":"1988","journal-title":"J Urol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib15","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/S0022-5347(17)53269-3","article-title":"Double-blind study with thiazide in recurrent calcium lithiasis","volume":"128","author":"Scholz","year":"1982","journal-title":"J Urol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib16","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0140-6736(81)90302-0","article-title":"Do thiazides prevent recurrent idiopathic renal calcium stones?","author":"Brocks","year":"1981","journal-title":"Lancet"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib17","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1056\/NEJMoa010369","article-title":"Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria","volume":"346","author":"Borghi","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib18","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1172\/JCI106889","article-title":"Changes in serum and urinary calcium during treatment with hydrochlorothiazide: studies on mechanisms","volume":"51","author":"Brickman","year":"1972","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib19","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1046\/j.1523-1755.2000.00221.x","article-title":"Comparative effects of potassium chloride and bicarbonate on thiazide-induced reduction in urinary calcium excretion","volume":"58","author":"Frasetto","year":"2000","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib20","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1210\/jcem-57-5-920","article-title":"Effect of amiloride with or without hydrochlorothiazide on urinary calcium and saturation of calcium salts","volume":"57","author":"Leppla","year":"1983","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib21","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.juro.2006.11.040","article-title":"Adverse metabolic side effects of thiazides: implications for patients with calcium nephrolithiasis","volume":"177","author":"Huen","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib22","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1097\/01.mnh.0000232880.58340.0c","article-title":"Bone disease in idiopathic hypercalciuria","volume":"15","author":"Heilberg","year":"2006","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib23","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1056\/NEJM198308113090605","article-title":"Thiazide effect on the mineral content of bone","volume":"309","author":"Wasnich","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib24","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1056\/NEJM199002013220502","article-title":"Thiazide diuretic agents and the incidence of hip fracture","volume":"322","author":"Lacroix","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib25","doi-asserted-by":"crossref","first-page":"476","DOI":"10.7326\/0003-4819-139-6-200309160-00010","article-title":"Thiazide diuretics and the risk of hip fracture","volume":"139","author":"Schoofs","year":"2003","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib26","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/S0002-9343(00)00510-6","article-title":"Hydrochlorothiazide reduces loss of cortical bone in normal postmenopausal women: a randomized controlled trial","volume":"109","author":"Reid","year":"2000","journal-title":"Am J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib27","doi-asserted-by":"crossref","first-page":"516","DOI":"10.7326\/0003-4819-133-7-200010030-00010","article-title":"Low-dose hydrochlorothiazide and preservation of bone mineral density in older adults","volume":"133","author":"Lacroix","year":"2000","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib28","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/BF01774014","article-title":"A randomized, double-masked, placebo-controlled trial of chlorthalidone and bone loss in elderly women","volume":"5","author":"Wasnich","year":"1995","journal-title":"Osteoporosis Int"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib29","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1056\/NEJM199511303332201","article-title":"Effect of oral alendronate on bone mineral density and the incidence of fractures in postmenopausal osteoporosis","volume":"333","author":"Liberman","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib30","doi-asserted-by":"crossref","first-page":"911.e9","DOI":"10.1016\/j.amjmed.2006.07.044","article-title":"Incidence and clinical spectrum of thiazide-associated hypercalcemia","volume":"120","author":"Wermers","year":"2007","journal-title":"Am J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib31","first-page":"338","article-title":"Thiazide therapy and severe hypercalcemia in a patient with hyperparathyroidism","volume":"154","author":"Strong","year":"1991","journal-title":"West J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib32","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.2215\/CJN.05970809","article-title":"Contribution of intestine, bone, kidney, and dialysis to extracellular fluid calcium content","volume":"5","author":"Bushinsky","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib33","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1056\/NEJMcp042806","article-title":"Hypercalcemia associated with cancer","volume":"352","author":"Stewart","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib34","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/ndt\/gfl718","article-title":"Mineral metabolism parameters throughout chronic kidney disease stages 1-5-achievement of K\/DOQI target ranges","volume":"22","author":"Craver","year":"2007","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib35","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1152\/ajplegacy.1971.220.1.49","article-title":"Effect of hypercalcemia on renal tubular sodium handling in the rat","volume":"220","author":"DiBona","year":"1971","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib36","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s002230010086","article-title":"Calcium-induced natriuresis: physiologic and clinical implications","volume":"66","author":"Adami","year":"2000","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib37","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1097\/01.mnh.0000242179.38739.fb","article-title":"Recent advances in renal tubular calcium reabsorption","volume":"15","author":"Mensenkamp","year":"2006","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib38","series-title":"Brenner and Rector's the kidney","first-page":"156","article-title":"Transport of inorganic solutes: sodium, chloride, potassium, magnesium, calcium and phosphate","author":"Mount","year":"2007"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib39","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1152\/ajplegacy.1973.225.1.119","article-title":"Furosemide effect on isolated perfused tubules","volume":"225","author":"Burg","year":"1973","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib40","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1172\/JCI109928","article-title":"Calcium transport in the thick ascending limb of Henle","volume":"66","author":"Suki","year":"1980","journal-title":"J Clin Invest"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib41","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1152\/ajplegacy.1961.200.5.1099","article-title":"Calcium clearance as a function of sodium clearance in the dog","volume":"200","author":"Walser","year":"1961","journal-title":"Am J Physiol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib42","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1056\/NEJM197010152831603","article-title":"Acute treatment of hypercalcemia with furosemide","volume":"283","author":"Suki","year":"1970","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib43","doi-asserted-by":"crossref","first-page":"259","DOI":"10.7326\/0003-4819-149-4-200808190-00007","article-title":"Narrative review: furosemide for hypercalcemia: an unproven yet common practice","volume":"149","author":"LeGrand","year":"2008","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib44","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/jbmr.5650080604","article-title":"Determinants of bone mineral density and risk factors for osteoporosis in healthy elderly women","volume":"8","author":"Ooms","year":"1993","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib45","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1359\/JBMR.051003","article-title":"Loop diuretics increase bone turnover and decrease BMD in osteopenic postmenopausal women: results from a randomized controlled study with bumetanide","volume":"21","author":"Rejnmark","year":"2006","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib46","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1001\/archinte.168.7.735","article-title":"Loop diuretic use and increased rates of hip bone loss in older men","volume":"168","author":"Lim","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib47","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1542\/peds.70.3.360","article-title":"Renal calcifications: a complication of long-term furosemide therapy in preterm infants","volume":"70","author":"Hufnagle","year":"1982","journal-title":"Pediatrics"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib48","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1097\/00008480-199704000-00008","article-title":"Nephrocalcinosis","volume":"9","author":"Alon","year":"1997","journal-title":"Curr Opin Pediatr"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib49","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1093\/ndt\/16.12.2303","article-title":"Medullary nephrocalcinosis associated with long-term furosemide abuse in adults","volume":"16","author":"Kim","year":"2001","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib50","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1001\/archinte.124.6.736","article-title":"Acetazolamide and sodium bicarbonate induced nephrocalcinosis and nephrolithiasis","volume":"124","author":"Parfitt","year":"1969","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib51","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1212\/WNL.43.6.1105","article-title":"Acetazolamide-induced nephrolithiasis: implications for treatment of neuromuscular disorders","volume":"43","author":"Tawil","year":"1993","journal-title":"Neurology"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib52","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1038\/ki.1990.265","article-title":"Renal handling of citrate","volume":"38","author":"Hamm","year":"1990","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib53","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/ki.1979.67","article-title":"Effects of metabolic acidosis and alkalosis on sodium and calcium transport in the dog kidney","volume":"15","author":"Sutton","year":"1979","journal-title":"Kidney Int"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib54","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1681\/ASN.2005070732","article-title":"Acid-base status determines the renal expression of Ca2+ and Mg2+ transport proteins","volume":"17","author":"Nijenhuis","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2011.09.008_bib55","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1053\/j.ajkd.2006.07.003","article-title":"Biochemical and stone-risk profiles with topiramate treatment","volume":"48","author":"Welch","year":"2006","journal-title":"Am J Kidney Dis"}],"container-title":["Seminars in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929511001379?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929511001379?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T04:54:07Z","timestamp":1639716847000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0270929511001379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":55,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0270929511001379"],"URL":"https:\/\/doi.org\/10.1016\/j.semnephrol.2011.09.008","relation":{},"ISSN":["0270-9295"],"issn-type":[{"value":"0270-9295","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]}}}