{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:00:33Z","timestamp":1790110833149,"version":"4.0.1"},"reference-count":92,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","seminarsinnephrology.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Nephrology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.semnephrol.2016.05.012","type":"journal-article","created":{"date-parts":[[2016,10,21]],"date-time":"2016-10-21T06:30:26Z","timestamp":1477031426000},"page":"351-361","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Cytomegalovirus and Other \u03b2-Herpesviruses"],"prefix":"10.1016","volume":"36","author":[{"given":"Carlos A.Q.","family":"Santos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semnephrol.2016.05.012_bib1","doi-asserted-by":"crossref","first-page":"12396","DOI":"10.1073\/pnas.1635160100","article-title":"Functional map of human cytomegalovirus AD169 defined by global mutational analysis","volume":"100","author":"Yu","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1128\/CMR.00122-14","article-title":"Laboratory and clinical aspects of human herpesvirus 6 infections","volume":"28","author":"Agut","year":"2015","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib3","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00705-013-1902-5","article-title":"Classification of HHV-6A and HHV-6B as distinct viruses","volume":"159","author":"Ablashi","year":"2014","journal-title":"Arch Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib4","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1006\/viro.1998.9105","article-title":"The DNA sequence of the RK strain of human herpesvirus 7","volume":"244","author":"Megaw","year":"1998","journal-title":"Virology"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib5","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1128\/CMR.00009-10","article-title":"Antiviral drug resistance of human cytomegalovirus","volume":"23","author":"Lurain","year":"2010","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib6","first-page":"933","article-title":"Ultrastructural characterization of a new human B lymphotropic DNA virus (human herpesvirus 6) isolated from patients with lymphoproliferative disease","volume":"79","author":"Biberfeld","year":"1987","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib7","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s004280050051","article-title":"Ultrastructural study of human herpesvirus-7 replication in tissue culture","volume":"430","author":"Klussmann","year":"1997","journal-title":"Virch Arch"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib8","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1128\/JVI.01599-10","article-title":"Human cytomegalovirus early protein pUL21a promotes efficient viral DNA synthesis and the late accumulation of immediate-early transcripts","volume":"85","author":"Fehr","year":"2011","journal-title":"J Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib9","doi-asserted-by":"crossref","first-page":"4841","DOI":"10.1128\/JVI.02344-10","article-title":"The human cytomegalovirus gene UL79 is required for the accumulation of late viral transcripts","volume":"85","author":"Perng","year":"2011","journal-title":"J Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib10","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1099\/vir.0.81374-0","article-title":"Human herpesvirus 7 U47 gene products are glycoproteins expressed in virions and associate with glycoprotein H","volume":"87","author":"Sadaoka","year":"2006","journal-title":"J Gen Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib11","first-page":"63","article-title":"Cytomegalovirus cell tropism","volume":"325","author":"Sinzger","year":"2008","journal-title":"Curr Top Microbiol Immunol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib12","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1128\/CMR.18.1.217-245.2005","article-title":"Update on human herpesvirus 6 biology, clinical features, and therapy","volume":"18","author":"De Bolle","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib13","doi-asserted-by":"crossref","first-page":"10552","DOI":"10.1073\/pnas.89.21.10552","article-title":"Human herpesvirus 7 is a T-lymphotropic virus and is related to, but significantly different from, human herpesvirus 6 and human cytomegalovirus","volume":"89","author":"Berneman","year":"1992","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib14","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.jcv.2007.11.014","article-title":"Human cytomegalovirus: latency and reactivation in the myeloid lineage","volume":"41","author":"Sinclair","year":"2008","journal-title":"J Clin Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib15","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1128\/JVI.68.2.1173-1178.1994","article-title":"Human herpesvirus 6 infects cervical epithelial cells and transactivates human papillomavirus gene expression","volume":"68","author":"Chen","year":"1994","journal-title":"J Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib16","doi-asserted-by":"crossref","first-page":"2705","DOI":"10.1099\/0022-1317-80-10-2705","article-title":"Temporal mapping of transcripts in human herpesvirus-7","volume":"80","author":"Menegazzi","year":"1999","journal-title":"J Gen Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib17","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1046\/j.1365-2141.1998.00903.x","article-title":"Integration of human herpesvirus 6 in a Burkitt\u05f3s lymphoma cell line","volume":"102","author":"Daibata","year":"1998","journal-title":"Br J Haematol"},{"issue":"Suppl 1","key":"10.1016\/j.semnephrol.2016.05.012_bib18","first-page":"S41","article-title":"Integration of human herpesvirus-6 (HHV-6) genome in chromosome 17 in two lymphoma patients","volume":"8","author":"Luppi","year":"1994","journal-title":"Leukemia"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib19","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1182\/blood.V94.5.1545","article-title":"Inheritance of chromosomally integrated human herpesvirus 6 DNA","volume":"94","author":"Daibata","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib20","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1084\/jem.190.2.177","article-title":"The dynamics of human cytomegalovirus replication in vivo","volume":"190","author":"Emery","year":"1999","journal-title":"J Exp Med"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib21","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1099\/0022-1317-72-6-1401","article-title":"Latent human herpesvirus 6 infection of human monocytes\/macrophages","volume":"72","author":"Kondo","year":"1991","journal-title":"J Gen Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib22","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1006\/viro.1994.1371","article-title":"Biological and molecular characteristics of human herpesvirus 7: in vitro growth optimization and development of a syncytia inhibition test","volume":"202","author":"Secchiero","year":"1994","journal-title":"Virology"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib23","doi-asserted-by":"crossref","first-page":"965","DOI":"10.2165\/10898540-000000000-00000","article-title":"New developments in the management of cytomegalovirus infection after solid organ transplantation","volume":"70","author":"Eid","year":"2010","journal-title":"Drugs"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib24","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1086\/379040","article-title":"Variation of human herpesvirus 7 shedding in saliva","volume":"188","author":"Ihira","year":"2003","journal-title":"J Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib25","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1093\/infdis\/jir722","article-title":"Cytomegalovirus survival on common environmental surfaces: opportunities for viral transmission","volume":"205","author":"Stowell","year":"2012","journal-title":"J Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib26","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1001\/archinte.1977.03630200034012","article-title":"Primary and secondary cytomegalovirus infection","volume":"137","author":"Suwansirikul","year":"1977","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib27","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1086\/528718","article-title":"Delayed-onset primary cytomegalovirus disease and the risk of allograft failure and mortality after kidney transplantation","volume":"46","author":"Arthurs","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib28","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/jmv.1890280203","article-title":"Brief report: primary human herpesvirus 6 infection in a patient following liver transplantation from a seropositive donor","volume":"28","author":"Ward","year":"1989","journal-title":"J Med Virol"},{"issue":"Suppl 3","key":"10.1016\/j.semnephrol.2016.05.012_bib29","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/ajt.12008","article-title":"Human herpesviruses 6, 7 and 8 in solid organ transplant recipients","volume":"13","author":"Razonable","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib30","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1086\/652438","article-title":"Cytomegalovirus seroprevalence in the United States: the national health and nutrition examination surveys, 1988-2004","volume":"50","author":"Bate","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib31","doi-asserted-by":"crossref","first-page":"6260","DOI":"10.1128\/JVI.65.11.6260-6265.1991","article-title":"Human herpesvirus 7: antigenic properties and prevalence in children and adults","volume":"65","author":"Wyatt","year":"1991","journal-title":"J Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib32","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0039-6060(97)90112-4","article-title":"Impact of cytomegalovirus serology on graft survival in living related kidney transplantation: implications for donor selection","volume":"121","author":"Schnitzler","year":"1997","journal-title":"Surgery"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib33","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/S0272-6386(97)90205-5","article-title":"The effects of cytomegalovirus serology on graft and recipient survival in cadaveric renal transplantation: implications for organ allocation","volume":"29","author":"Schnitzler","year":"1997","journal-title":"Am J Kidney Dis"},{"issue":"Suppl 4","key":"10.1016\/j.semnephrol.2016.05.012_bib34","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/ajt.12093","article-title":"Introduction: infections in solid organ transplantation","volume":"13","author":"Green","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib35","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1086\/339329","article-title":"Definitions of cytomegalovirus infection and disease in transplant recipients","volume":"34","author":"Ljungman","year":"2002","journal-title":"Clin Infect Dis"},{"issue":"Suppl:","key":"10.1016\/j.semnephrol.2016.05.012_bib36","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1097\/01.tp.0000230460.42558.b0","article-title":"The natural course of cytomegalovirus infection and disease in renal transplant recipients","volume":"82","author":"Hartmann","year":"2006","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib37","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1034\/j.1600-6143.2002.20907.x","article-title":"The impact of cytomegalovirus infection and disease on rejection episodes in renal allograft recipients","volume":"2","author":"Sagedal","year":"2002","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib38","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1523-1755.2004.00735.x","article-title":"Impact of early cytomegalovirus infection and disease on long-term recipient and kidney graft survival","volume":"66","author":"Sagedal","year":"2004","journal-title":"Kidney Int"},{"issue":"Suppl 4","key":"10.1016\/j.semnephrol.2016.05.012_bib39","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/ajt.12103","article-title":"Infectious AST Diseases Community of Practice. Cytomegalovirus in solid organ transplantation","volume":"13","author":"Razonable","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib40","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1097\/TP.0000000000000030","article-title":"Delayed-onset cytomegalovirus disease coded during hospital readmission after kidney transplantation","volume":"98","author":"Santos","year":"2014","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib41","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/clinids\/22.1.171","article-title":"Longitudinal study of human herpesvirus 6 infection in organ transplant recipients","volume":"22","author":"Herbein","year":"1996","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib42","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1086\/315477","article-title":"The prevalence of human herpesvirus-7 in renal transplant recipients is unaffected by oral or intravenous ganciclovir","volume":"181","author":"Brennan","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib43","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1086\/466529","article-title":"Herpesvirus infections in solid organ transplant patients at high risk of primary cytomegalovirus disease","volume":"192","author":"Razonable","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib44","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0166-3542(98)00049-7","article-title":"Comparison of antiviral compounds against human herpesvirus 6 and 7","volume":"40","author":"Yoshida","year":"1998","journal-title":"Antiviral Res"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib45","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1097\/00007890-199712270-00036","article-title":"Prophylactic oral ganciclovir compared with deferred therapy for control of cytomegalovirus in renal transplant recipients","volume":"64","author":"Brennan","year":"1997","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib46","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1056\/NEJM199905133401903","article-title":"Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group","volume":"340","author":"Lowance","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib47","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/j.1600-6143.2004.00382.x","article-title":"Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients","volume":"4","author":"Paya","year":"2004","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib48","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1111\/j.1600-6143.2010.03074.x","article-title":"The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients","volume":"10","author":"Humar","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib49","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1111\/j.1600-6143.2007.02133.x","article-title":"Improvement in long-term renal graft survival due to CMV prophylaxis with oral ganciclovir: results of a randomized clinical trial","volume":"8","author":"Kliem","year":"2008","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib50","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1111\/j.1600-6143.2006.01413.x","article-title":"Prophylactic versus preemptive oral valganciclovir for the management of cytomegalovirus infection in adult renal transplant recipients","volume":"6","author":"Khoury","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib51","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1600-6143.2007.02031.x","article-title":"Valacyclovir prophylaxis versus preemptive valganciclovir therapy to prevent cytomegalovirus disease after renal transplantation","volume":"8","author":"Reischig","year":"2008","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib52","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/TP.0b013e318238dab3","article-title":"Valganciclovir prophylaxis versus preemptive therapy in cytomegalovirus-positive renal allograft recipients: 1-year results of a randomized clinical trial","volume":"93","author":"Witzke","year":"2012","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib53","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/jmv.23539","article-title":"High risk of cytomegalovirus infection following solid organ transplantation despite prophylactic therapy","volume":"85","author":"Harvala","year":"2013","journal-title":"J Med Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib54","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.1016\/j.transproceed.2015.04.087","article-title":"Accuracy of inpatient International Classification of Diseases, Ninth Revision, Clinical Modification coding for cytomegalovirus after kidney transplantation","volume":"47","author":"Santos","year":"2015","journal-title":"Transplant Proc"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib55","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1681\/ASN.V8111801","article-title":"Does cytomegalovirus cause glomerular injury in renal allograft recipients?","volume":"8","author":"Birk","year":"1997","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib56","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1053\/j.ajkd.2013.08.021","article-title":"Cytomegalovirus glomerulopathy and cytomegalovirus interstitial nephritis on sequential transplant kidney biopsies","volume":"63","author":"Vichot","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib57","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1093\/ndt\/18.2.397","article-title":"CMV infection of the renal allograft is much more common than the pathology indicates: a retrospective analysis of qualitative and quantitative buffy coat CMV-PCR, renal biopsy pathology and tissue CMV-PCR","volume":"18","author":"Liapis","year":"2003","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib58","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S1047-2797(01)00283-6","article-title":"Hospitalizations for cytomegalovirus disease after renal transplantation in the United States","volume":"12","author":"Abbott","year":"2002","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib59","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0966-3274(99)80023-9","article-title":"Role of cytomegalovirus infection in allograft rejection: a review of possible mechanisms","volume":"7","author":"Borchers","year":"1999","journal-title":"Transplant Immunol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib60","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1111\/j.1600-6143.2009.02618.x","article-title":"Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients","volume":"9","author":"Kumar","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib61","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.1399-3062.2010.00532.x","article-title":"Choice of induction regimens on the risk of cytomegalovirus infection in donor-positive and recipient-negative kidney transplant recipients","volume":"12","author":"Luan","year":"2010","journal-title":"Transplant Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib62","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1034\/j.1399-0012.2000.140206.x","article-title":"Mycophenolate mofetil increases cytomegalovirus invasive organ disease in renal transplant patients","volume":"14","author":"Sarmiento","year":"2000","journal-title":"Clin Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib63","doi-asserted-by":"crossref","first-page":"18","DOI":"10.7326\/0003-4819-123-1-199507010-00002","article-title":"Preemptive ganciclovir therapy to prevent cytomegalovirus disease in cytomegalovirus antibody-positive renal transplant recipients. A randomized controlled trial","volume":"123","author":"Hibberd","year":"1995","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib64","doi-asserted-by":"crossref","unstructured":"Conti DJ, Freed BM, Singh TP, Gallichio M, Gruber SA, Lempert N. Preemptive ganciclovir therapy in cytomegalovirus-seropositive renal transplants recipients. Arch Surg. 1995;130:1217-1221; discussion 1221-2.","DOI":"10.1001\/archsurg.1995.01430110075014"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib65","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1034\/j.1399-0012.2003.02104.x","article-title":"Detection of simultaneous beta-herpesvirus infections in clinical syndromes due to defined cytomegalovirus infection","volume":"17","author":"Razonable","year":"2003","journal-title":"Clin Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib66","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1002\/lt.21816","article-title":"A report of human herpesvirus 6-associated encephalitis in a solid organ transplant recipient and a review of previously published cases","volume":"15","author":"Vinnard","year":"2009","journal-title":"Liver Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib67","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1111\/j.1600-6143.2004.00459.x","article-title":"Encephalitis owing to human herpesvirus-6 after cardiac transplant","volume":"4","author":"Nash","year":"2004","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib68","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1399-3062.2006.00143.x","article-title":"Colitis in a renal transplant patient with human herpesvirus-6 infection","volume":"8","author":"Delbridge","year":"2006","journal-title":"Transplant Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib69","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1097\/00007890-200101270-00021","article-title":"Fatal primary infection due to human herpesvirus 6 variant A in a renal transplant recipient","volume":"71","author":"Rossi","year":"2001","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib70","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/TP.0b013e3181601413","article-title":"Human herpesvirus 7 primary infection in kidney transplant recipients","volume":"85","author":"Anton","year":"2008","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib71","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1038\/sj.bmt.1703774","article-title":"Human herpesvirus-7 infection of the CNS with acute myelitis in an adult bone marrow recipient","volume":"30","author":"Ward","year":"2002","journal-title":"Bone Marrow Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib72","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1086\/317929","article-title":"Human beta-herpesvirus interactions in solid organ transplant recipients","volume":"183","author":"Mendez","year":"2001","journal-title":"J Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib73","first-page":"213","article-title":"Association of human herpesvirus 7 with cytomegalovirus disease in renal transplant recipients","volume":"70","author":"Tong","year":"2000","journal-title":"Transplantation"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib74","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1093\/cid\/cis900","article-title":"An international multicenter performance analysis of cytomegalovirus load tests","volume":"56","author":"Hirsch","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib75","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1093\/cid\/cit096","article-title":"Virologic suppression measured by a cytomegalovirus (CMV) DNA test calibrated to the World Health Organization international standard is predictive of CMV disease resolution in transplant recipients","volume":"56","author":"Razonable","year":"2013","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib76","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.jcv.2012.09.017","article-title":"Determination, validation and standardization of a CMV DNA cut-off value in plasma for preemptive treatment of CMV infection in solid organ transplant recipients at lower risk for CMV infection","volume":"56","author":"Martin-Gandul","year":"2013","journal-title":"J Clin Virol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib77","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1128\/JCM.40.3.746-752.2002","article-title":"Role of the laboratory in diagnosis and management of cytomegalovirus infection in hematopoietic stem cell and solid-organ transplant recipients","volume":"40","author":"Razonable","year":"2002","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib78","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1128\/CMR.00015-13","article-title":"Clinical utility of viral load in management of cytomegalovirus infection after solid organ transplantation","volume":"26","author":"Razonable","year":"2013","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib79","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/j.1399-0012.1997.tb00821.x","article-title":"Diagnosing cytomegalovirus disease in CMV seropositive renal allograft recipients: a comparison between the detection of CMV DNAemia by polymerase chain reaction and antigenemia by CMV pp65 assay","volume":"11","author":"Lo","year":"1997","journal-title":"Clin Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib80","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1600-6143.2009.02861.x","article-title":"Clinical predictors of relapse after treatment of primary gastrointestinal cytomegalovirus disease in solid organ transplant recipients","volume":"10","author":"Eid","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib81","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1136\/jcp.53.8.612","article-title":"Histopathological detection of owl\u05f3s eye inclusions is still specific for cytomegalovirus in the era of human herpesviruses 6 and 7","volume":"53","author":"Mattes","year":"2000","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib82","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/hep.1840120119","article-title":"Early diagnosis of cytomegalovirus hepatitis in liver transplant recipients: role of immunostaining, DNA hybridization and culture of hepatic tissue","volume":"12","author":"Paya","year":"1990","journal-title":"Hepatology"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib83","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1399-3062.2007.00241.x","article-title":"Clinical features and outcomes of cytomegalovirus retinitis after transplantation","volume":"10","author":"Eid","year":"2008","journal-title":"Transplant Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib84","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1111\/j.1600-6143.2007.01910.x","article-title":"Oral valganciclovir is noninferior to intravenous ganciclovir for the treatment of cytomegalovirus disease in solid organ transplant recipients","volume":"7","author":"Asberg","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib85","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1086\/338362","article-title":"Cytomegalovirus UL97 phosphotransferase mutations that affect susceptibility to ganciclovir","volume":"185","author":"Chou","year":"2002","journal-title":"J Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib86","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1086\/514041","article-title":"High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes","volume":"176","author":"Smith","year":"1997","journal-title":"J Infect Dis"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib87","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1056\/NEJMoa1303688","article-title":"CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation","volume":"369","author":"Marty","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib88","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1128\/AAC.01596-09","article-title":"In vitro and in vivo activities of the novel anticytomegalovirus compound AIC246","volume":"54","author":"Lischka","year":"2010","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib89","first-page":"269","article-title":"Letermovir and inhibitors of the terminase complex: a promising new class of investigational antiviral drugs against human cytomegalovirus","volume":"8","author":"Melendez","year":"2015","journal-title":"Infect Drug Resist"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib90","first-page":"3560","article-title":"Successful treatment of severe cytomegalovirus infections with ganciclovir and CMV hyperimmune globulin in liver transplant recipients","volume":"21","author":"D\u05f3Alessandro","year":"1989","journal-title":"Transplant Proc"},{"issue":"Suppl 4","key":"10.1016\/j.semnephrol.2016.05.012_bib91","first-page":"22","article-title":"Use of ganciclovir plus cytomegalovirus immune globulin to treat CMV pneumonia in orthotopic liver transplant recipients. The Boston Center for Liver Transplantation CMVIG-Study Group","volume":"25","author":"George","year":"1993","journal-title":"Transplant Proc"},{"key":"10.1016\/j.semnephrol.2016.05.012_bib92","first-page":"271","article-title":"Hyperimmune immunoglobulin therapy for cytomegalovirus infections in renal transplant patients","volume":"20","author":"Brown","year":"1983","journal-title":"Proc Eur Dial Transplant Assoc"}],"container-title":["Seminars in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929516300432?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929516300432?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T18:56:29Z","timestamp":1749668189000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0270929516300432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":92,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0270929516300432"],"URL":"https:\/\/doi.org\/10.1016\/j.semnephrol.2016.05.012","relation":{},"ISSN":["0270-9295"],"issn-type":[{"value":"0270-9295","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cytomegalovirus and Other \u03b2-Herpesviruses","name":"articletitle","label":"Article Title"},{"value":"Seminars in Nephrology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semnephrol.2016.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}