{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:16:51Z","timestamp":1788405411956,"version":"build-2803163510"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","seminarsinnephrology.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Nephrology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.semnephrol.2026.151721","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:06:09Z","timestamp":1788404769000},"page":"151721","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Phosphorus Intake and Outcomes in Chronic Kidney Disease: Cardiovascular, Skeletal, and Mortality Risks"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6593-3571","authenticated-orcid":false,"given":"Orlando M.","family":"Guti\u00e9rrez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.semnephrol.2026.151721_bib0001","series-title":"Clinical Aspects of Natural and Added Phosphorus in Foods","first-page":"3","article-title":"The story of phosphorus","author":"Guti\u00e9rrez","year":"2017"},{"issue":"6","key":"10.1016\/j.semnephrol.2026.151721_bib0002","doi-asserted-by":"crossref","first-page":"723","DOI":"10.3945\/an.113.004812","article-title":"The connection between dietary phosphorus, cardiovascular disease, and mortality: where we stand and what we need to know","volume":"4","author":"Guti\u00e9rrez","year":"2013","journal-title":"Adv Nutr"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0003","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1053\/j.ackd.2012.10.008","article-title":"Sodium- and phosphorus-based food additives: persistent but surmountable hurdles in the management of nutrition in chronic kidney disease","volume":"20","author":"Guti\u00e9rrez","year":"2013","journal-title":"Adv Chronic Kidney Dis"},{"key":"10.1016\/j.semnephrol.2026.151721_bib0004","series-title":"Present Knowledge in Nutrition","first-page":"335","article-title":"Phosphorus","author":"Guti\u00e9rrez","year":"2020"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0005","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1053\/j.ackd.2010.11.004","article-title":"Intestinal phosphate transport","volume":"18","author":"Sabbagh","year":"2011","journal-title":"Adv Chronic Kidney Dis"},{"issue":"4","key":"10.1016\/j.semnephrol.2026.151721_bib0006","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1152\/physrev.2000.80.4.1373","article-title":"Proximal tubular phosphate reabsorption: molecular mechanisms","volume":"80","author":"Murer","year":"2000","journal-title":"Physiol Rev"},{"issue":"6","key":"10.1016\/j.semnephrol.2026.151721_bib0007","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1681\/ASN.2007010068","article-title":"How fibroblast growth factor 23 works","volume":"18","author":"Liu","year":"2007","journal-title":"J Am Soc Nephrol"},{"issue":"9","key":"10.1016\/j.semnephrol.2026.151721_bib0008","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.2215\/CJN.02640310","article-title":"Fibroblast growth factor 23 and disordered vitamin D metabolism in chronic kidney disease: updating the \u201ctrade-off\u201d hypothesis","volume":"5","author":"Guti\u00e9rrez","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"issue":"4 suppl 1","key":"10.1016\/j.semnephrol.2026.151721_bib0009","doi-asserted-by":"crossref","first-page":"S34","DOI":"10.1053\/ajkd.2001.27394","article-title":"Vascular calcification and inorganic phosphate","volume":"38","author":"Giachelli","year":"2001","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0010","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1053\/j.ackd.2010.12.002","article-title":"Direct effects of phosphate on vascular cell function","volume":"18","author":"Lau","year":"2011","journal-title":"Adv Chronic Kidney Dis"},{"issue":"6","key":"10.1016\/j.semnephrol.2026.151721_bib0011","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1681\/ASN.2007070760","article-title":"The mechanism of phosphorus as a cardiovascular risk factor in CKD","volume":"19","author":"Mathew","year":"2008","journal-title":"J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.semnephrol.2026.151721_bib0012","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1681\/ASN.2009060640","article-title":"Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification","volume":"21","author":"Shroff","year":"2010","journal-title":"J Am Soc Nephrol"},{"issue":"12","key":"10.1016\/j.semnephrol.2026.151721_bib0013","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1038\/ki.2009.83","article-title":"Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin","volume":"75","author":"El-Abbadi","year":"2009","journal-title":"Kidney Int"},{"issue":"9","key":"10.1016\/j.semnephrol.2026.151721_bib0014","doi-asserted-by":"crossref","first-page":"2778","DOI":"10.1681\/ASN.2005040392","article-title":"Effects of short daily versus conventional hemodialysis on left ventricular hypertrophy and inflammatory markers: a prospective, controlled study","volume":"16","author":"Ayus","year":"2005","journal-title":"J Am Soc Nephrol"},{"issue":"4","key":"10.1016\/j.semnephrol.2026.151721_bib0015","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1365-2796.2005.01544.x","article-title":"Left ventricular function and calcium phosphate plasma levels in uraemic patients","volume":"258","author":"Galetta","year":"2005","journal-title":"J Intern Med"},{"issue":"6","key":"10.1016\/j.semnephrol.2026.151721_bib0016","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1111\/j.1523-1755.2004.66013.x","article-title":"Adverse effects of hyperphosphatemia on myocardial hypertrophy, renal function, and bone in rats with renal failure","volume":"66","author":"Neves","year":"2004","journal-title":"Kidney Int"},{"issue":"7","key":"10.1016\/j.semnephrol.2026.151721_bib0017","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1681\/ASN.2008101106","article-title":"Dietary phosphorus acutely impairs endothelial function","volume":"20","author":"Shuto","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.semnephrol.2026.151721_bib0018","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.advenzreg.2006.01.003","article-title":"A novel function of phosphate-mediated intracellular signal transduction pathways","volume":"46","author":"Takeda","year":"2006","journal-title":"Adv Enzyme Regul"},{"issue":"10","key":"10.1016\/j.semnephrol.2026.151721_bib0019","doi-asserted-by":"crossref","first-page":"2754","DOI":"10.1093\/ndt\/gfl270","article-title":"High-calcium vs high-phosphate intake and small artery tone in advanced experimental renal insufficiency","volume":"21","author":"Koobi","year":"2006","journal-title":"Nephrol Dial Transplant"},{"issue":"10","key":"10.1016\/j.semnephrol.2026.151721_bib0020","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.2215\/CJN.02420409","article-title":"Mineral metabolism and inflammation in chronic kidney disease patients: a cross-sectional study","volume":"4","author":"Navarro-Gonzalez","year":"2009","journal-title":"Clin J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.semnephrol.2026.151721_bib0021","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3109\/0886022X.2010.528116","article-title":"Reduction of hyperphosphatemia is related with the reduction of C-reactive protein in dialysis patients. Study in sevelamer-resistant dialysis patients treated with chitosan chewing gum as salivary phosphate binder","volume":"33","author":"Calo","year":"2011","journal-title":"Ren Fail"},{"issue":"3","key":"10.1016\/j.semnephrol.2026.151721_bib0022","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1542-4758.2009.00369.x","article-title":"Effect of phosphate binders on oxidative stress and inflammation markers in hemodialysis patients","volume":"13","author":"Peres","year":"2009","journal-title":"Hemodial Int"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0023","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1159\/000111061","article-title":"Effects of sevelamer and calcium-based phosphate binders on lipid and inflammatory markers in hemodialysis patients","volume":"28","author":"Shantouf","year":"2008","journal-title":"Am J Nephrol"},{"issue":"9","key":"10.1016\/j.semnephrol.2026.151721_bib0024","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1681\/ASN.2006080936","article-title":"Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) study","volume":"18","author":"Fliser","year":"2007","journal-title":"J Am Soc Nephrol"},{"issue":"6","key":"10.1016\/j.semnephrol.2026.151721_bib0025","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1056\/NEJMoa0706130","article-title":"Fibroblast growth factor 23 and mortality among patients undergoing hemodialysis","volume":"359","author":"Gutierrez","year":"2008","journal-title":"N Engl J Med"},{"issue":"23","key":"10.1016\/j.semnephrol.2026.151721_bib0026","doi-asserted-by":"crossref","first-page":"2432","DOI":"10.1001\/jama.2011.826","article-title":"Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease","volume":"305","author":"Isakova","year":"2011","journal-title":"JAMA"},{"issue":"12","key":"10.1016\/j.semnephrol.2026.151721_bib0027","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.1093\/ndt\/gfq309","article-title":"FGF-23 and future cardiovascular events in patients with chronic kidney disease before initiation of dialysis treatment","volume":"25","author":"Seiler","year":"2010","journal-title":"Nephrol Dial Transplant"},{"issue":"9","key":"10.1016\/j.semnephrol.2026.151721_bib0028","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1093\/ndt\/gfp191","article-title":"High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients","volume":"24","author":"Jean","year":"2009","journal-title":"Nephrol Dial Transplant"},{"issue":"10","key":"10.1016\/j.semnephrol.2026.151721_bib0029","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1681\/ASN.2010121224","article-title":"FGF-23 associates with death, cardiovascular events, and initiation of chronic dialysis","volume":"22","author":"Kendrick","year":"2011","journal-title":"J Am Soc Nephrol"},{"issue":"11","key":"10.1016\/j.semnephrol.2026.151721_bib0030","doi-asserted-by":"crossref","first-page":"4393","DOI":"10.1172\/JCI46122","article-title":"FGF23 induces left ventricular hypertrophy","volume":"121","author":"Faul","year":"2011","journal-title":"J Clin Invest"},{"issue":"19","key":"10.1016\/j.semnephrol.2026.151721_bib0031","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1161\/CIRCULATIONAHA.108.844506","article-title":"Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease","volume":"119","author":"Gutierrez","year":"2009","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0032","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.atherosclerosis.2009.05.013","article-title":"Serum intact FGF23 associate with left ventricular mass, hypertrophy and geometry in an elderly population","volume":"207","author":"Mirza","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.semnephrol.2026.151721_bib0033","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.yjmcc.2019.11.149","article-title":"FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice","volume":"138","author":"Han","year":"2020","journal-title":"J Mol Cell Cardiol"},{"issue":"4","key":"10.1016\/j.semnephrol.2026.151721_bib0034","doi-asserted-by":"crossref","first-page":"683","DOI":"10.2215\/CJN.08601209","article-title":"Association of dietary phosphorus intake and phosphorus to protein ratio with mortality in hemodialysis patients","volume":"5","author":"Noori","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"issue":"19","key":"10.1016\/j.semnephrol.2026.151721_bib0035","doi-asserted-by":"crossref","first-page":"4064","DOI":"10.3390\/nu14194064","article-title":"Dietary phosphorus, its sources, and mortality in adults on haemodialysis: the DIET-HD study","volume":"14","author":"Su","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.semnephrol.2026.151721_bib0036","article-title":"Associations of dietary phosphorus-protein ratio, phosphorus-energy ratio, and protein-energy ratio with mortality in peritoneal dialysis patients: a retrospective cohort study","volume":"13","author":"Wang","year":"2026","journal-title":"Front Nutr"},{"issue":"15","key":"10.1016\/j.semnephrol.2026.151721_bib0037","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.3390\/nu14153070","article-title":"The interplay between dietary phosphorous, protein intake, and mortality in a prospective hemodialysis cohort","volume":"14","author":"Brown-Tortorici","year":"2022","journal-title":"Nutrients"},{"issue":"3","key":"10.1016\/j.semnephrol.2026.151721_bib0038","doi-asserted-by":"crossref","first-page":"620","DOI":"10.2215\/CJN.04620510","article-title":"Prescribed dietary phosphate restriction and survival among hemodialysis patients","volume":"6","author":"Lynch","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"issue":"3","key":"10.1016\/j.semnephrol.2026.151721_bib0039","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1093\/ndt\/gfr367","article-title":"Dietary phosphorus intake and mortality in moderate chronic kidney disease: NHANES III","volume":"27","author":"Murtaugh","year":"2012","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"10.1016\/j.semnephrol.2026.151721_bib0040","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1038\/ki.2015.284","article-title":"Relationship of dietary phosphate intake with risk of end-stage renal disease and mortality in chronic kidney disease stages 3-5: the Modification of Diet in Renal Disease study","volume":"89","author":"Selamet","year":"2016","journal-title":"Kidney Int"},{"issue":"7","key":"10.1016\/j.semnephrol.2026.151721_bib0041","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.2215\/CJN.00390118","article-title":"Twenty-four-hour urine phosphorus as a biomarker of dietary phosphorus intake and absorption in CKD: a secondary analysis from a controlled diet balance study","volume":"13","author":"Stremke","year":"2018","journal-title":"Clin J Am Soc Nephrol"},{"issue":"8","key":"10.1016\/j.semnephrol.2026.151721_bib0042","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1681\/ASN.2020091340","article-title":"Intestinal phosphorus absorption in moderate CKD and healthy adults determined using a radioisotopic tracer","volume":"32","author":"Stremke","year":"2021","journal-title":"J Am Soc Nephrol"},{"issue":"11","key":"10.1016\/j.semnephrol.2026.151721_bib0043","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.2215\/CJN.0000000000000538","article-title":"Association of intake of whole grains with health outcomes in the Chronic Renal Insufficiency Cohort Study","volume":"19","author":"Winkelman","year":"2024","journal-title":"Clin J Am Soc Nephrol"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0044","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1681\/ASN.2008060609","article-title":"Phosphorus binders and survival on hemodialysis","volume":"20","author":"Isakova","year":"2009","journal-title":"J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.semnephrol.2026.151721_bib0045","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1053\/j.ajkd.2011.12.025","article-title":"Phosphate binder use and mortality among hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS): evaluation of possible confounding by nutritional status","volume":"60","author":"Lopes","year":"2012","journal-title":"Am J Kidney Dis"},{"issue":"5","key":"10.1016\/j.semnephrol.2026.151721_bib0046","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1038\/ki.2013.185","article-title":"Use of phosphate-binding agents is associated with a lower risk of mortality","volume":"84","author":"Cannata-And\u00eda","year":"2013","journal-title":"Kidney Int"},{"issue":"1","key":"10.1016\/j.semnephrol.2026.151721_bib0047","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-29757-0","article-title":"Use of phosphate-binders and risk of infection-related and all-cause mortality in patients undergoing hemodialysis: the Q-Cohort Study","volume":"8","author":"Yamada","year":"2018","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.semnephrol.2026.151721_bib0048","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1053\/j.ajkd.2010.06.011","article-title":"Outcomes associated with phosphorus binders in men with non\u2013dialysis-dependent CKD","volume":"56","author":"Kovesdy","year":"2010","journal-title":"Am J Kidney Dis"},{"issue":"8","key":"10.1016\/j.semnephrol.2026.151721_bib0049","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1681\/ASN.2012030223","article-title":"Effects of phosphate binders in moderate CKD","volume":"23","author":"Block","year":"2012","journal-title":"J Am Soc Nephrol"},{"issue":"11","key":"10.1016\/j.semnephrol.2026.151721_bib0050","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1681\/ASN.2020040411","article-title":"A randomized trial on the effect of phosphate reduction on vascular end points in CKD (IMPROVE-CKD)","volume":"31","author":"Toussaint","year":"2020","journal-title":"J Am Soc Nephrol"},{"issue":"5","key":"10.1016\/j.semnephrol.2026.151721_bib0051","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1053\/j.ajkd.2016.05.015","article-title":"Phosphate-binding agents in adults with CKD: a network meta-analysis of randomized trials","volume":"68","author":"Palmer","year":"2016","journal-title":"Am J Kidney Dis"},{"issue":"6","key":"10.1016\/j.semnephrol.2026.151721_bib0052","article-title":"Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)","volume":"6","author":"Natale","year":"2025","journal-title":"Cochrane Database Syst Rev"},{"issue":"5","key":"10.1016\/j.semnephrol.2026.151721_bib0053","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1001\/archinte.1969.00300150061009","article-title":"Calcium, phosphorus, and bone in renal disease and transplantation","volume":"123","author":"Bricker","year":"1969","journal-title":"Arch Intern Med"},{"issue":"5","key":"10.1016\/j.semnephrol.2026.151721_bib0054","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s11914-017-0398-4","article-title":"Effects of excessive dietary phosphorus intake on bone health","volume":"15","author":"Vorland","year":"2017","journal-title":"Curr Osteoporos Rep"},{"issue":"7","key":"10.1016\/j.semnephrol.2026.151721_bib0055","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1093\/ajcn\/33.7.1546","article-title":"Early dietary phosphorus restriction and calcium supplementation in the prevention of renal osteodystrophy","volume":"33","author":"Maschio","year":"1980","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.semnephrol.2026.151721_bib0056","first-page":"S71","article-title":"Is phosphate more important than protein in low-protein diets?","volume":"17","author":"Maschio","year":"1985","journal-title":"Kidney Int Suppl"},{"issue":"5","key":"10.1016\/j.semnephrol.2026.151721_bib0057","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.3945\/ajcn.114.085498","article-title":"Effect of dietary phosphate intake on the circadian rhythm of serum phosphate concentrations in chronic kidney disease: a crossover study","volume":"100","author":"Ix","year":"2014","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0058","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1053\/j.ajkd.2016.08.029","article-title":"Phosphorus additives and albuminuria in early stages of CKD: a randomized controlled trial","volume":"69","author":"Chang","year":"2017","journal-title":"Am J Kidney Dis"},{"issue":"7","key":"10.1016\/j.semnephrol.2026.151721_bib0059","doi-asserted-by":"crossref","first-page":"950","DOI":"10.2215\/CJN.0000000730","article-title":"Effects of lowering dietary phosphorus additive intake on mineral metabolism in adults with and without CKD","volume":"20","author":"Khan","year":"2025","journal-title":"Clin J Am Soc Nephrol"},{"issue":"1","key":"10.1016\/j.semnephrol.2026.151721_bib0060","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1093\/jn\/107.1.42","article-title":"Physiological responses of human adults to foods containing phosphate additives","volume":"107","author":"Bell","year":"1977","journal-title":"J Nutr"},{"key":"10.1016\/j.semnephrol.2026.151721_bib0061","first-page":"284","article-title":"On the ratio of calcium and phosphorus in human nutrition","volume":"38","author":"Feldheim","year":"1983","journal-title":"Milchwissenschaft"},{"key":"10.1016\/j.semnephrol.2026.151721_bib0062","first-page":"78","article-title":"Phosphorus intake of Americans","volume":"36","author":"Greger","year":"1982","journal-title":"Food Technol"},{"issue":"2","key":"10.1016\/j.semnephrol.2026.151721_bib0063","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1365-2621.1983.tb10791.x","article-title":"Zinc, iron and copper availability as affected by orthophosphates, polyphosphates and calcium","volume":"48","author":"Zemel","year":"1983","journal-title":"J Food Sci"},{"issue":"9","key":"10.1016\/j.semnephrol.2026.151721_bib0064","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/S0002-8223(21)07957-8","article-title":"Accuracy of methods estimating calcium and phosphorus intake in daily diets","volume":"88","author":"Oenning","year":"1988","journal-title":"J Am Diet Assoc"},{"issue":"4","key":"10.1016\/j.semnephrol.2026.151721_bib0065","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1053\/j.jrn.2012.12.003","article-title":"The prevalence of phosphorus-containing food additives in top-selling foods in grocery stores","volume":"23","author":"Le\u00f3n","year":"2013","journal-title":"J Ren Nutr"},{"issue":"1","key":"10.1016\/j.semnephrol.2026.151721_bib0066","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1053\/j.jrn.2013.09.003","article-title":"Contribution of food additives to sodium and phosphorus content of diets rich in processed foods","volume":"24","author":"Carrigan","year":"2014","journal-title":"J Ren Nutr"}],"container-title":["Seminars in Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929526000409?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0270929526000409?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:06:23Z","timestamp":1788404783000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0270929526000409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":66,"alternative-id":["S0270929526000409"],"URL":"https:\/\/doi.org\/10.1016\/j.semnephrol.2026.151721","relation":{},"ISSN":["0270-9295"],"issn-type":[{"value":"0270-9295","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phosphorus Intake and Outcomes in Chronic Kidney Disease: Cardiovascular, Skeletal, and Mortality Risks","name":"articletitle","label":"Article Title"},{"value":"Seminars in Nephrology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semnephrol.2026.151721","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"151721"}}