{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T20:42:23Z","timestamp":1774039343937,"version":"3.50.1"},"reference-count":78,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Radiation Oncology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.semradonc.2025.08.001","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T14:28:07Z","timestamp":1757514487000},"page":"598-607","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Moving Beyond the Standard Pancreatectomy for Pancreatic Adenocarcinoma"],"prefix":"10.1016","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2042-7947","authenticated-orcid":false,"given":"Madeleine D.","family":"Hunter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nupur","family":"Shridhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Mlouk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg D.","family":"Sacks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Wolfgang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Kluger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0001","doi-asserted-by":"crossref","first-page":"10","DOI":"10.14740\/wjon1166","article-title":"Epidemiology of pancreatic cancer: global trends, etiology and risk factors","volume":"10","author":"Rawla","year":"2019","journal-title":"World J Oncol"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0002","series-title":"StatPearls","article-title":"Distal pancreatectomy","author":"Bishop","year":"2025"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0003","series-title":"Cancer stat facts: pancreatic cancer","year":"2025"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0004","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1477-2574.2011.00305.x","article-title":"History of pancreaticoduodenectomy: early misconceptions, initial milestones and the pioneers","volume":"13","author":"Are","year":"2011","journal-title":"HPB (Oxford)"},{"issue":"5","key":"10.1016\/j.semradonc.2025.08.001_bib0005","first-page":"247","article-title":"Pancreatic surgery: evolution and current tailored approach","volume":"3","author":"Zovak","year":"2014","journal-title":"Hepatobiliary Surg Nutr"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0006","series-title":"StatPearls","article-title":"Pancreaticoduodenectomy (Whipple Procedure)","author":"D\u2019Cruz","year":"2025"},{"issue":"2","key":"10.1016\/j.semradonc.2025.08.001_bib0007","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1001\/archsurg.137.2.164","article-title":"The value of splenic preservation with distal pancreatectomy","volume":"137","author":"Shoup","year":"2002","journal-title":"Arch Surg"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0008","doi-asserted-by":"crossref","DOI":"10.1093\/bjs\/znad424","article-title":"Outcomes after distal pancreatectomy with or without splenectomy for intraductal papillary mucinous neoplasm: international multicentre cohort study","volume":"111","author":"Gorris","year":"2024","journal-title":"Br J Surg"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0009","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.hpb.2023.02.009","article-title":"Kimura's vs Warshaw's technique for spleen preserving distal pancreatectomy: a systematic review and meta-analysis of high-quality studies","volume":"25","author":"Granieri","year":"2023","journal-title":"HPB (Oxford)"},{"issue":"4","key":"10.1016\/j.semradonc.2025.08.001_bib0010","first-page":"349","article-title":"[Central pancreatectomy. Indications and perisurgical results of a pancreatic tissue conservation technique]","volume":"25","author":"Celis Zapata","year":"2005","journal-title":"Rev Gastroenterol Peru"},{"issue":"42","key":"10.1016\/j.semradonc.2025.08.001_bib0011","doi-asserted-by":"crossref","first-page":"15674","DOI":"10.3748\/wjg.v20.i42.15674","article-title":"Central pancreatectomy: the Dagradi Serio Iacono operation. Evolution of a surgical technique from the pioneers to the robotic approach","volume":"20","author":"Iacono","year":"2014","journal-title":"World J Gastroenterol"},{"issue":"7","key":"10.1016\/j.semradonc.2025.08.001_bib0012","article-title":"Central pancreatectomy for central pancreatic lesions: a single-institution experience","volume":"13","author":"SK","year":"2021","journal-title":"Cureus"},{"issue":"10","key":"10.1016\/j.semradonc.2025.08.001_bib0013","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.hpb.2018.05.001","article-title":"The role of central pancreatectomy in pancreatic surgery: a systematic review and meta-analysis","volume":"20","author":"Xiao","year":"2018","journal-title":"HPB (Oxford)"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0014","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/00000658-197707000-00007","article-title":"Regional pancreatectomy: en bloc pancreatic, portal vein and lymph node resection","volume":"186","author":"Fortner","year":"1977","journal-title":"Ann Surg"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0015","series-title":"Pancreatic Adenocarcinoma: Version 2.2025","year":"2025"},{"issue":"5","key":"10.1016\/j.semradonc.2025.08.001_bib0016","doi-asserted-by":"crossref","first-page":"669","DOI":"10.2217\/fon.15.335","article-title":"The role of neoadjuvant therapy in pancreatic cancer: a review","volume":"12","author":"Russo","year":"2016","journal-title":"Future Oncol"},{"issue":"7","key":"10.1016\/j.semradonc.2025.08.001_bib0017","doi-asserted-by":"crossref","first-page":"6575","DOI":"10.3390\/curroncol30070482","article-title":"Adjuvant chemotherapy and radiotherapy in resected pancreatic ductal adenocarcinoma: a systematic review and clinical practice guideline","volume":"30","author":"Biagi","year":"2023","journal-title":"Curr Oncol"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0018","doi-asserted-by":"crossref","first-page":"27","DOI":"10.21037\/tgh.2019.04.04","article-title":"Adjuvant treatment for pancreatic cancer","volume":"4","author":"Klaiber","year":"2019","journal-title":"Transl Gastroenterol Hepatol"},{"issue":"14","key":"10.1016\/j.semradonc.2025.08.001_bib0019","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1001\/jama.2013.279201","article-title":"Adjuvant chemotherapy with gemcitabine and long-term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial","volume":"310","author":"Oettle","year":"2013","journal-title":"JAMA"},{"issue":"12","key":"10.1016\/j.semradonc.2025.08.001_bib0020","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1056\/NEJMoa032295","article-title":"A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer","volume":"350","author":"Neoptolemos","year":"2004","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.semradonc.2025.08.001_bib0021","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1001\/jama.2010.1275","article-title":"Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial","volume":"304","author":"Neoptolemos","year":"2010","journal-title":"JAMA"},{"issue":"19","key":"10.1016\/j.semradonc.2025.08.001_bib0022","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1056\/NEJMoa1011923","article-title":"FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer","volume":"364","author":"Conroy","year":"2011","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.semradonc.2025.08.001_bib0023","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1001\/jamaoncol.2022.3829","article-title":"Five-year outcomes of FOLFIRINOX vs Gemcitabine as adjuvant therapy for pancreatic cancer: a randomized clinical trial","volume":"8","author":"Conroy","year":"2022","journal-title":"JAMA Oncol"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0024","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.16199","article-title":"Comparison of FOLFIRINOX vs Gemcitabine plus Nab-Paclitaxel as first-line chemotherapy for metastatic pancreatic ductal adenocarcinoma","volume":"5","author":"Klein-Brill","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0025","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.annepidem.2022.12.005","article-title":"Head-to-head comparison of FOLFIRINOX versus gemcitabine plus nab-paclitaxel in advanced pancreatic cancer: a target trial emulation using real-world data","volume":"78","author":"Boyne","year":"2023","journal-title":"Ann Epidemiol"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0026","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s13304-021-01186-1","article-title":"Neoadjuvant therapy for pancreatic cancer","volume":"74","author":"Gugenheim","year":"2022","journal-title":"Updates Surg"},{"issue":"2","key":"10.1016\/j.semradonc.2025.08.001_bib0027","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.hpb.2019.06.019","article-title":"The risk of not receiving adjuvant chemotherapy after resection of pancreatic ductal adenocarcinoma: a nationwide analysis","volume":"22","author":"Mackay","year":"2020","journal-title":"HPB (Oxford)"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0028","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s11605-013-2412-1","article-title":"Treatment sequencing for resectable pancreatic cancer: influence of early metastases and surgical complications on multimodality therapy completion and survival","volume":"18","author":"Tzeng","year":"2014","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0029","series-title":"NCCN Guideline Version 2.2025: pancreatic adenocarcinoma","year":"2025"},{"issue":"3","key":"10.1016\/j.semradonc.2025.08.001_bib0030","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S2468-1253(23)00405-3","article-title":"Neoadjuvant FOLFIRINOX versus upfront surgery for resectable pancreatic head cancer (NORPACT-1): a multicentre, randomised, phase 2 trial","volume":"9","author":"Labori","year":"2024","journal-title":"Lancet Gastroenterol Hepatol"},{"issue":"17","key":"10.1016\/j.semradonc.2025.08.001_bib0031","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1200\/JCO-24-01378","article-title":"Neoadjuvant FOLF(IRIN)OX chemotherapy for resectable pancreatic adenocarcinoma: a multicenter randomized noncomparative Phase II trial (PANACHE01 FRENCH08 PRODIGE48 study)","volume":"43","author":"Schwarz","year":"2025","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0032","doi-asserted-by":"crossref","DOI":"10.1097\/SLA.0000000000006730","article-title":"Neoadjuvant chemotherapy with Gemcitabine and S-1 versus upfront surgery for resectable pancreatic cancer: results of the randomized phase II\/III prep-02\/JSAP05 trial","author":"Unno","year":"2025","journal-title":"Ann Surg"},{"issue":"11","key":"10.1016\/j.semradonc.2025.08.001_bib0033","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1200\/JCO.21.02233","article-title":"Neoadjuvant chemoradiotherapy versus upfront surgery for resectable and borderline resectable pancreatic cancer: long-term results of the Dutch randomized PREOPANC trial","volume":"40","author":"Versteijne","year":"2022","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0034","doi-asserted-by":"crossref","first-page":"S9","DOI":"10.1016\/j.hpb.2024.03.017","article-title":"Neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy for borderline resectable and resectable pancreatic cancer (PREOPANC-2): a multicenter randomized controlled trial","volume":"26","author":"Janssen","year":"2024","journal-title":"HPB"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0035","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1186\/s12885-021-08031-z","volume":"21","author":"Janssen","year":"2021","journal-title":"BMC Cancer"},{"issue":"7","key":"10.1016\/j.semradonc.2025.08.001_bib0036","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1001\/jamaoncol.2018.0329","article-title":"Total neoadjuvant therapy with FOLFIRINOX followed by individualized chemoradiotherapy for borderline resectable pancreatic adenocarcinoma: a phase 2 clinical trial","volume":"4","author":"Murphy","year":"2018","journal-title":"JAMA Oncol"},{"issue":"2","key":"10.1016\/j.semradonc.2025.08.001_bib0037","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/SLA.0000000000002705","article-title":"Oncological benefits of neoadjuvant chemoradiation with Gemcitabine versus upfront surgery in patients with borderline resectable pancreatic cancer: a prospective, randomized, open-label, Multicenter Phase 2\/3 trial","volume":"268","author":"Jang","year":"2018","journal-title":"Ann Surg"},{"issue":"10","key":"10.1016\/j.semradonc.2025.08.001_bib0038","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1001\/jamasurg.2019.2277","article-title":"Outcomes of primary chemotherapy for borderline resectable and locally advanced pancreatic ductal adenocarcinoma","volume":"154","author":"Maggino","year":"2019","journal-title":"JAMA Surg"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0039","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/SLA.0000000000004915","article-title":"Surgical decision-making in pancreatic ductal adenocarcinoma: modeling prognosis following pancreatectomy in the era of induction and neoadjuvant chemotherapy","volume":"277","author":"Habib","year":"2023","journal-title":"Ann Surg"},{"issue":"2","key":"10.1016\/j.semradonc.2025.08.001_bib0040","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/SLA.0000000000003284","article-title":"Factors predicting response, perioperative outcomes, and survival following total neoadjuvant therapy for borderline\/locally advanced pancreatic cancer","volume":"273","author":"Truty","year":"2021","journal-title":"Ann Surg"},{"issue":"3","key":"10.1016\/j.semradonc.2025.08.001_bib0041","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jamcollsurg.2013.11.017","article-title":"Portal vein resection in borderline resectable pancreatic cancer: a United Kingdom multicenter study","volume":"218","author":"Ravikumar","year":"2014","journal-title":"J Am Coll Surg"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0042","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.pan.2022.05.001","article-title":"Venous resection for pancreatic cancer, a safe and feasible option? A systematic review and meta-analysis","volume":"22","author":"Zwart","year":"2022","journal-title":"Pancreatology"},{"issue":"11","key":"10.1016\/j.semradonc.2025.08.001_bib0043","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/bjs.10580","article-title":"Impact of portal vein infiltration and type of venous reconstruction in surgery for borderline resectable pancreatic cancer","volume":"104","author":"Ravikumar","year":"2017","journal-title":"Br J Surg"},{"issue":"5","key":"10.1016\/j.semradonc.2025.08.001_bib0044","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.pan.2017.08.005","article-title":"Pancreatectomy with venous resection for pT3 head adenocarcinoma: perioperative outcomes, recurrence pattern and prognostic implications of histologically confirmed vascular infiltration","volume":"17","author":"Malleo","year":"2017","journal-title":"Pancreatology"},{"issue":"8","key":"10.1016\/j.semradonc.2025.08.001_bib0045","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.ejso.2023.03.229","article-title":"Pancreatectomy with venous vascular resection for pancreatic cancer: impact of types of vein resection on timing and pattern of recurrence","volume":"49","author":"Tamburrino","year":"2023","journal-title":"Eur J Surg Oncol"},{"issue":"3","key":"10.1016\/j.semradonc.2025.08.001_bib0046","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s00423-017-1578-5","article-title":"Combined hepatic arterial resection in pancreatic resections for locally advanced pancreatic cancer","volume":"402","author":"Miyazaki","year":"2017","journal-title":"Langenbecks Arch Surg"},{"issue":"11","key":"10.1016\/j.semradonc.2025.08.001_bib0047","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1007\/s00268-019-05106-8","article-title":"Pancreatectomy with hepatic artery resection for pancreatic head cancer","volume":"43","author":"Yang","year":"2019","journal-title":"World J Surg"},{"issue":"11","key":"10.1016\/j.semradonc.2025.08.001_bib0048","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1016\/j.hpb.2022.06.005","article-title":"Patency rates of hepatic arterial resection and revascularization in locally advanced pancreatic cancer","volume":"24","author":"Alva-Ruiz","year":"2022","journal-title":"HPB (Oxford)"},{"issue":"4","key":"10.1016\/j.semradonc.2025.08.001_bib0049","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1002\/1097-0142(195307)6:4<704::AID-CNCR2820060410>3.0.CO;2-P","article-title":"The coeliac axis in the expansion of the operation for gastric carcinoma","volume":"6","author":"Appleby","year":"1953","journal-title":"Cancer"},{"issue":"11","key":"10.1016\/j.semradonc.2025.08.001_bib0050","doi-asserted-by":"crossref","first-page":"3757","DOI":"10.1245\/s10434-016-5303-3","article-title":"Modified Appleby procedure for pancreatic adenocarcinoma: does improved neoadjuvant therapy warrant such an aggressive approach?","volume":"23","author":"Peters","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0051","doi-asserted-by":"crossref","DOI":"10.1016\/j.hpb.2025.04.009","article-title":"Distal pancreatectomy with celiac axis resection (DP-CAR) for pancreatic ductal adenocarcinoma in a retrospective monocentric cohort: neoadjuvant treatment and three-axis embolization of the celiac axis are key factors of success","author":"Bertrand","year":"2025","journal-title":"HPB (Oxford)"},{"issue":"7","key":"10.1016\/j.semradonc.2025.08.001_bib0052","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1002\/jso.26424","article-title":"Distal pancreatectomy with en bloc celiac axis resection (DP-CAR) and arterial reconstruction: techniques and outcomes","volume":"123","author":"Addeo","year":"2021","journal-title":"J Surg Oncol"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0053","doi-asserted-by":"crossref","first-page":"e1210","DOI":"10.1097\/SLA.0000000000005866","article-title":"Distal pancreatectomy with en bloc celiac axis resection (DP-CAR) for locally advanced pancreatic cancer: a safe and effective procedure","volume":"278","author":"Loos","year":"2023","journal-title":"Ann Surg"},{"issue":"5","key":"10.1016\/j.semradonc.2025.08.001_bib0054","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1245\/s10434-018-6391-z","article-title":"Outcomes after distal pancreatectomy with celiac axis resection for pancreatic cancer: a Pan-European retrospective cohort study","volume":"25","author":"Klompmaker","year":"2018","journal-title":"Ann Surg Oncol"},{"issue":"3","key":"10.1016\/j.semradonc.2025.08.001_bib0055","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1245\/s10434-018-07101-0","article-title":"Outcomes and risk score for distal pancreatectomy with celiac axis resection (DP-CAR): an international multicenter analysis","volume":"26","author":"Klompmaker","year":"2019","journal-title":"Ann Surg Oncol"},{"issue":"7","key":"10.1016\/j.semradonc.2025.08.001_bib0056","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1007\/s11605-019-04324-8","article-title":"Efficacy of neoadjuvant chemotherapy in distal pancreatectomy with en bloc celiac axis resection (DP-CAR) for locally advanced pancreatic cancer","volume":"24","author":"Yoshiya","year":"2020","journal-title":"J Gastrointest Surg"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0057","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jamcollsurg.2020.05.005","article-title":"En bloc celiac axis resection for pancreatic cancer: classification of anatomical variants based on tumor extent","volume":"231","author":"Truty","year":"2020","journal-title":"J Am Coll Surg"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0058","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/SLA.0000000000003859","article-title":"Prognosis based definition of resectability in pancreatic cancer: a road map to new guidelines","volume":"275","author":"Oba","year":"2022","journal-title":"Ann Surg"},{"issue":"2","key":"10.1016\/j.semradonc.2025.08.001_bib0059","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/SLA.0000000000002753","article-title":"Survival in locally advanced pancreatic cancer after neoadjuvant therapy and surgical resection","volume":"270","author":"Gemenetzis","year":"2019","journal-title":"Ann Surg"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0060","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1245\/s10434-021-10663-1","article-title":"Anatomic criteria determine resectability in locally advanced pancreatic cancer","volume":"29","author":"Gemenetzis","year":"2022","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0061","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.pan.2023.06.005","article-title":"Conversion surgery\" for locally advanced pancreatic cancer: a position paper by the study group at the joint meeting of the International Association of Pancreatology (IAP) & Japan Pancreas Society (JPS) 2022","volume":"23","author":"Oba","year":"2023","journal-title":"Pancreatology"},{"issue":"3","key":"10.1016\/j.semradonc.2025.08.001_bib0062","doi-asserted-by":"crossref","DOI":"10.3390\/cancers16030489","article-title":"Anatomical and biological considerations to determine resectability in pancreatic cancer","volume":"16","author":"Rompen","year":"2024","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.semradonc.2025.08.001_bib0063","first-page":"559","article-title":"Arterial divestment instead of resection for locally advanced pancreatic cancer (LAPC)","author":"Miao","year":"2016","journal-title":"Abstracts"},{"issue":"3","key":"10.1016\/j.semradonc.2025.08.001_bib0064","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00423-021-02080-5","article-title":"Sub-adventitial divestment technique for resecting artery-involved pancreatic cancer: a retrospective cohort study","volume":"406","author":"Cai","year":"2021","journal-title":"Langenbecks Arch Surg"},{"issue":"7","key":"10.1016\/j.semradonc.2025.08.001_bib0065","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1007\/s11605-018-3995-3","article-title":"Optimal extent of superior mesenteric artery dissection during pancreaticoduodenectomy for pancreatic cancer: balancing surgical and oncological safety","volume":"23","author":"Inoue","year":"2019","journal-title":"J Gastrointest Surg"},{"issue":"5","key":"10.1016\/j.semradonc.2025.08.001_bib0066","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1097\/SLA.0000000000003010","article-title":"Pancreatectomy with arterial resection for pancreatic adenocarcinoma: how can it Be done safely and with which outcomes?: a single institution's experience with 118 patients","volume":"271","author":"Bachellier","year":"2020","journal-title":"Ann Surg"},{"issue":"7","key":"10.1016\/j.semradonc.2025.08.001_bib0067","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.hpb.2020.04.005","article-title":"Arterial resections in pancreatic cancer - systematic review and meta-analysis","volume":"22","author":"Ma\u0142czak","year":"2020","journal-title":"HPB (Oxford)"},{"issue":"8","key":"10.1016\/j.semradonc.2025.08.001_bib0068","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/bjs\/znac363","article-title":"Pancreatectomy with resection and reconstruction of the superior mesenteric artery","volume":"110","author":"Boggi","year":"2023","journal-title":"Br J Surg"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0069","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1097\/SLA.0000000000006350","article-title":"Outcomes of visceral arterial interposition graft reconstruction for locally advanced pancreatic cancer","volume":"281","author":"Yonkus","year":"2025","journal-title":"Ann Surg"},{"issue":"4","key":"10.1016\/j.semradonc.2025.08.001_bib0070","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1097\/SLA.0000000000004054","article-title":"Arterial resection in pancreatic cancer surgery: effective after a learning curve","volume":"275","author":"Loos","year":"2022","journal-title":"Ann Surg"},{"issue":"2","key":"10.1016\/j.semradonc.2025.08.001_bib0071","doi-asserted-by":"crossref","DOI":"10.1093\/bjsopen\/zraf026","article-title":"Arterial resection and divestment in pancreatic cancer surgery in the era of multidisciplinary treatment: decadal comparative study","volume":"9","author":"Hirose","year":"2025","journal-title":"BJS Open"},{"issue":"4","key":"10.1016\/j.semradonc.2025.08.001_bib0072","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.jacbts.2018.01.014","article-title":"Radiation-induced endothelial vascular injury: a review of possible mechanisms","volume":"3","author":"Venkatesulu","year":"2018","journal-title":"JACC Basic Transl Sci"},{"issue":"5","key":"10.1016\/j.semradonc.2025.08.001_bib0073","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.jtcvs.2008.07.005","article-title":"Conduit choice for coronary artery bypass grafting after mediastinal radiation","volume":"136","author":"Brown","year":"2008","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.semradonc.2025.08.001_bib0074","doi-asserted-by":"crossref","DOI":"10.1136\/openhrt-2017-000766","article-title":"Coronary artery bypass grafting in patients treated with thoracic radiation: a case-control study","volume":"5","author":"Fender","year":"2018","journal-title":"Open Heart"},{"issue":"8","key":"10.1016\/j.semradonc.2025.08.001_bib0075","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1245\/s10434-017-5885-4","article-title":"Downstaging in stage IV pancreatic cancer: a new population eligible for surgery?","volume":"24","author":"Frigerio","year":"2017","journal-title":"Ann Surg Oncol"},{"issue":"6","key":"10.1016\/j.semradonc.2025.08.001_bib0076","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/j.surg.2021.12.029","article-title":"Surgical treatment of hepatic oligometastatic pancreatic ductal adenocarcinoma: an analysis of the National Cancer Database","volume":"171","author":"Hamad","year":"2022","journal-title":"Surgery"},{"issue":"9","key":"10.1016\/j.semradonc.2025.08.001_bib0077","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14092067","article-title":"Can surgical resection of metastatic lesions Be beneficial to pancreatic ductal adenocarcinoma patients with isolated lung metastasis?","volume":"14","author":"Yun","year":"2022","journal-title":"Cancers (Basel)"},{"issue":"5","key":"10.1016\/j.semradonc.2025.08.001_bib0078","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1002\/jhbp.1127","article-title":"Outcomes of lung metastasis from pancreatic cancer: a nationwide multicenter analysis","volume":"29","author":"Homma","year":"2022","journal-title":"J Hepatobiliary Pancreat Sci"}],"container-title":["Seminars in Radiation Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053429625000657?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1053429625000657?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T00:10:48Z","timestamp":1760227848000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1053429625000657"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":78,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1053429625000657"],"URL":"https:\/\/doi.org\/10.1016\/j.semradonc.2025.08.001","relation":{},"ISSN":["1053-4296"],"issn-type":[{"value":"1053-4296","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Moving Beyond the Standard Pancreatectomy for Pancreatic Adenocarcinoma","name":"articletitle","label":"Article Title"},{"value":"Seminars in Radiation Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.semradonc.2025.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}