{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:06:42Z","timestamp":1790485602718,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2008,2,1]],"date-time":"2008-02-01T00:00:00Z","timestamp":1201824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Seminars in Fetal and Neonatal Medicine"],"published-print":{"date-parts":[[2008,2]]},"DOI":"10.1016\/j.siny.2007.09.004","type":"journal-article","created":{"date-parts":[[2007,12,26]],"date-time":"2007-12-26T16:24:39Z","timestamp":1198686279000},"page":"30-34","source":"Crossref","is-referenced-by-count":31,"title":["Current controversies in hypothermic neuroprotection"],"prefix":"10.1016","volume":"13","author":[{"given":"John D.E.","family":"Barks","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.siny.2007.09.004_bib1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pediatrneurol.2004.06.014","article-title":"Moderate hypothermia in neonatal encephalopathy: efficacy outcomes","volume":"32","author":"Eicher","year":"2005","journal-title":"Pediatr Neurol"},{"issue":"9460","key":"10.1016\/j.siny.2007.09.004_bib2","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0140-6736(05)17946-X","article-title":"Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial","volume":"365","author":"Gluckman","year":"2005","journal-title":"Lancet"},{"issue":"15","key":"10.1016\/j.siny.2007.09.004_bib3","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1056\/NEJMcps050929","article-title":"Whole-body hypothermia for neonates with hypoxic\u2013ischemic encephalopathy","volume":"353","author":"Shankaran","year":"2005","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.siny.2007.09.004_bib4","doi-asserted-by":"crossref","first-page":"F127","DOI":"10.1136\/adc.2005.071787","article-title":"Therapeutic hypothermia following perinatal asphyxia","volume":"91","author":"Edwards","year":"2006","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"5","key":"10.1016\/j.siny.2007.09.004_bib5","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1542\/peds.2006-2776","article-title":"Cooling for neonatal hypoxic\u2013ischemic encephalopathy \u2013 is the answer in?","volume":"120","author":"Kirpalani","year":"2007","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.siny.2007.09.004_bib6","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jpeds.2005.12.009","article-title":"Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop","volume":"148","author":"Higgins","year":"2006","journal-title":"J Pediatr"},{"issue":"3","key":"10.1016\/j.siny.2007.09.004_bib7","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1542\/peds.2005-2950","article-title":"Hypothermia: a neuroprotective therapy for neonatal hypoxic\u2013ischemic encephalopathy","volume":"117","author":"Blackmon","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.siny.2007.09.004_bib8","unstructured":"Gray J, Geva A, Zheng Z, Zupancic J. CoolSim: using industrial modeling techniques to examine the impact of selective head cooling in a model of perinatal regionalization. Pediatrics, in press."},{"issue":"1","key":"10.1016\/j.siny.2007.09.004_bib9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0378-3782(98)00033-4","article-title":"The \u2018pharmacology\u2019 of neuronal rescue with cerebral hypothermia","volume":"53","author":"Gunn","year":"1998","journal-title":"Early Hum Dev"},{"issue":"1","key":"10.1016\/j.siny.2007.09.004_bib10","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.pediatrneurol.2004.06.015","article-title":"Moderate hypothermia in neonatal encephalopathy: safety outcomes","volume":"32","author":"Eicher","year":"2005","journal-title":"Pediatr Neurol"},{"issue":"2","key":"10.1016\/j.siny.2007.09.004_bib11","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0887-8994(92)90026-U","article-title":"Problems with definitions and classifications of newborn encephalopathy","volume":"8","author":"Leviton","year":"1992","journal-title":"Pediatr Neurol"},{"issue":"5","key":"10.1016\/j.siny.2007.09.004_bib12","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1542\/peds.2006-2839","article-title":"Determinants of outcomes after head cooling for neonatal encephalopathy","volume":"119","author":"Wyatt","year":"2007","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.siny.2007.09.004_bib13","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1542\/peds.2006-1591","article-title":"Predicting outcomes of neonates diagnosed with hypoxemic\u2013ischemic encephalopathy","volume":"118","author":"Ambalavanan","year":"2006","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.siny.2007.09.004_bib14","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1161\/01.STR.0000128029.50221.fa","article-title":"Topiramate extends the therapeutic window for hypothermia-mediated neuroprotection after stroke in neonatal rats","volume":"35","author":"Liu","year":"2004","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.siny.2007.09.004_bib15","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1203\/01.pdr.0000215045.91122.44","article-title":"Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic\u2013ischemic brain injury in neonatal rats","volume":"59","author":"Jatana","year":"2006","journal-title":"Pediatr Res"},{"key":"10.1016\/j.siny.2007.09.004_bib16","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.brainres.2007.03.083","article-title":"\u2018Therapeutic time window\u2019 duration decreases with increasing severity of cerebral hypoxia\u2013ischaemia under normothermia and delayed hypothermia in newborn piglets","volume":"1154","author":"Iwata","year":"2007","journal-title":"Brain Res"},{"issue":"6","key":"10.1016\/j.siny.2007.09.004_bib17","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1016\/j.jpeds.2004.07.034","article-title":"Randomized trial of systemic hypothermia selectively protects the cortex on MRI in term hypoxic\u2013ischemic encephalopathy","volume":"145","author":"Inder","year":"2004","journal-title":"J Pediatr"},{"issue":"4","key":"10.1016\/j.siny.2007.09.004_bib18","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1542\/peds.2005-0328","article-title":"Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic\u2013ischemic encephalopathy","volume":"116","author":"Rutherford","year":"2005","journal-title":"Pediatrics"}],"container-title":["Seminars in Fetal and Neonatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744165X07001084?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744165X07001084?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,2]],"date-time":"2019-01-02T02:21:12Z","timestamp":1546395672000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1744165X07001084"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,2]]}},"alternative-id":["S1744165X07001084"],"URL":"https:\/\/doi.org\/10.1016\/j.siny.2007.09.004","relation":{},"ISSN":["1744-165X"],"issn-type":[{"value":"1744-165X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,2]]}}}