{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T02:59:44Z","timestamp":1793501984555,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T00:00:00Z","timestamp":1606521600000},"content-version":"vor","delay-in-days":58,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","sfnmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Seminars in Fetal and Neonatal Medicine"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.siny.2020.101144","type":"journal-article","created":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T12:15:50Z","timestamp":1596284150000},"page":"101144","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Assessment of neonatal perfusion"],"prefix":"10.1016","volume":"25","author":[{"given":"Samir","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M.","family":"Donn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.siny.2020.101144_bib1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.earlhumdev.2010.01.033","article-title":"Peripheral haemodynamics in newborns: best practice guidelines","volume":"86","author":"Weindling","year":"2010","journal-title":"Early Hum Dev"},{"issue":"6","key":"10.1016\/j.siny.2020.101144_bib2","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/pr.2014.40","article-title":"Respiratory support for premature neonates in the delivery room: effects on cardiovascular function and the development of brain injury","volume":"75","author":"Polglase","year":"2014","journal-title":"Pediatr Res"},{"issue":"6","key":"10.1016\/j.siny.2020.101144_bib3","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s00431-013-2251-9","article-title":"International survey on diagnosis and management of hypotension in extremely preterm babies","volume":"173","author":"Stranak","year":"2014","journal-title":"Eur J Pediatr"},{"issue":"10 Spec No","key":"10.1016\/j.siny.2020.101144_bib4","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1136\/adc.67.10_Spec_No.1221","volume":"67","year":"1992","journal-title":"Arch Dis Child"},{"issue":"10","key":"10.1016\/j.siny.2020.101144_bib5","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1136\/adc.62.10.1068","article-title":"Mean arterial blood pressure and neonatal cerebral lesions","volume":"62","author":"Miall-Allen","year":"1987","journal-title":"Arch Dis Child"},{"issue":"2","key":"10.1016\/j.siny.2020.101144_bib6","doi-asserted-by":"crossref","first-page":"F168","DOI":"10.1136\/adc.2002.023796","article-title":"Clinical detection of low upper body blood flow in very premature infants using blood pressure, capillary refill time, and central-peripheral temperature difference","volume":"89","author":"Osborn","year":"2004","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"1","key":"10.1016\/j.siny.2020.101144_bib7","doi-asserted-by":"crossref","first-page":"F15","DOI":"10.1136\/fn.76.1.F15","article-title":"Association between blood lactate and acid-base status and mortality in ventilated babies","volume":"76","author":"Deshpande","year":"1997","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"1","key":"10.1016\/j.siny.2020.101144_bib8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.siny.2013.09.006","article-title":"Neonatal hypotension: dopamine or dobutamine?","volume":"19","author":"Gupta","year":"2014","journal-title":"Semin Fetal Neonatal Med"},{"issue":"3","key":"10.1016\/j.siny.2020.101144_bib9","doi-asserted-by":"crossref","first-page":"F182","DOI":"10.1136\/fn.82.3.F182","article-title":"Superior vena cava flow in newborn infants: a novel marker of systemic blood flow","volume":"82","author":"Kluckow","year":"2000","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"4","key":"10.1016\/j.siny.2020.101144_bib10","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s00392-009-0745-2","article-title":"The basic pacing rate in CRT patients: the higher the better?","volume":"98","author":"Voss","year":"2009","journal-title":"Clin Res Cardiol"},{"issue":"1","key":"10.1016\/j.siny.2020.101144_bib11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12871-019-0744-4","article-title":"Reliability of pleth variability index in predicting preload responsiveness of mechanically ventilated patients under various conditions: a systematic review and meta-analysis","volume":"19","author":"Liu","year":"2019","journal-title":"BMC Anesthesiol"},{"issue":"3","key":"10.1016\/j.siny.2020.101144_bib12","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1053\/j.jvca.2016.12.009","article-title":"Electrical Cardiometry: a reliable solution to cardiac output estimation in children with structural heart disease","volume":"31","author":"Narula","year":"2017","journal-title":"J\u00a0Cardiothorac Vasc Anesth"},{"issue":"5","key":"10.1016\/j.siny.2020.101144_bib13","doi-asserted-by":"crossref","first-page":"F340","DOI":"10.1136\/fetalneonatal-2011-301090","article-title":"Continuous non-invasive cardiac output measurements in the neonate by electrical velocimetry: a comparison with echocardiography","volume":"97","author":"Noori","year":"2012","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"10.1016\/j.siny.2020.101144_bib14","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3389\/fped.2014.00016","article-title":"Non-invasive cardiac output measurement in low and very low birth weight infants: a method comparison","volume":"2","author":"Grollmuss","year":"2014","journal-title":"Front Pediatr"},{"issue":"7","key":"10.1016\/j.siny.2020.101144_bib15","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1038\/jp.2014.245","article-title":"Influence of patent ductus arteriosus and ventilators on electrical velocimetry for measuring cardiac output in very-low\/low birth weight infants","volume":"35","author":"Torigoe","year":"2015","journal-title":"J\u00a0Perinatol"},{"issue":"3","key":"10.1016\/j.siny.2020.101144_bib16","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1159\/000501005","article-title":"Cardiac output measurement using the ultrasonic cardiac output monitor: a validation study in newborn infants","volume":"116","author":"Fraga","year":"2019","journal-title":"Neonatology"},{"issue":"4","key":"10.1016\/j.siny.2020.101144_bib17","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1038\/s41390-018-0118-5","article-title":"Comprehensive state-of-the-art overview of neonatologist performed echocardiography: steps towards standardization of the use of echocardiography in neonatal intensive care","volume":"84","author":"de Boode","year":"2018","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.siny.2020.101144_bib18","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41390-018-0078-9","article-title":"Education, training, and accreditation of neonatologist performed echocardiography in europe-framework for practice","volume":"84","author":"Singh","year":"2018","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.siny.2020.101144_bib19","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/s41390-018-0081-1","article-title":"The role of Neonatologist Performed Echocardiography in the assessment and management of neonatal shock","volume":"84","author":"de Boode","year":"2018","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.siny.2020.101144_bib20","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/s41390-018-0079-8","article-title":"European Special Interest Group 'Neonatologist Performed E. Tissue Doppler velocity imaging and event timings in neonates: a guide to image acquisition, measurement, interpretation, and reference values","volume":"84","author":"Nestaas","year":"2018","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.siny.2020.101144_bib21","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/s41390-018-0080-2","article-title":"European Special Interest Group 'Neonatologist Performed E. Deformation imaging and rotational mechanics in neonates: a guide to image acquisition, measurement, interpretation, and reference values","volume":"84","author":"El-Khuffash","year":"2018","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.siny.2020.101144_bib22","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/s41390-018-0075-z","article-title":"Application of neonatologist performed echocardiography in the assessment and management of neonatal heart failure unrelated to congenital heart disease","volume":"84","author":"Levy","year":"2018","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.siny.2020.101144_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41390-018-0076-y","article-title":"Introduction to neonatologist-performed echocardiography","volume":"84","author":"Groves","year":"2018","journal-title":"Pediatr Res"},{"issue":"Suppl 1","key":"10.1016\/j.siny.2020.101144_bib24","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/s41390-018-0077-x","article-title":"Application of NPE in the assessment of a patent ductus arteriosus","volume":"84","author":"van Laere","year":"2018","journal-title":"Pediatr Res"},{"issue":"4","key":"10.1016\/j.siny.2020.101144_bib25","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.siny.2018.03.007","article-title":"Role of neonatologist-performed echocardiography in the assessment and management of patent ductus arteriosus physiology in the newborn","volume":"23","author":"de Boode","year":"2018","journal-title":"Semin Fetal Neonatal Med"},{"issue":"4","key":"10.1016\/j.siny.2020.101144_bib26","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/pr.2016.126","article-title":"Recommendations for neonatologist performed echocardiography in europe: consensus statement endorsed by European society for paediatric research (ESPR) and European society for Neonatology (ESN)","volume":"80","author":"de Boode","year":"2016","journal-title":"Pediatr Res"},{"issue":"2","key":"10.1016\/j.siny.2020.101144_bib27","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1007\/s00431-015-2633-2","article-title":"Expert consensus statement 'Neonatologist-performed echocardiography (NoPE)'-training and accreditation in UK","volume":"175","author":"Singh","year":"2016","journal-title":"Eur J Pediatr"},{"issue":"12","key":"10.1016\/j.siny.2020.101144_bib28","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/S0002-9149(99)80419-6","article-title":"Noninvasive assessment of myocardial contractility, preload, and afterload in healthy newborn infants","volume":"75","author":"Rowland","year":"1995","journal-title":"Am J Cardiol"},{"issue":"3","key":"10.1016\/j.siny.2020.101144_bib29","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0167-5273(98)00047-3","article-title":"Maturational changes in left ventricular contractile state","volume":"64","author":"Toyono","year":"1998","journal-title":"Int J Cardiol"},{"issue":"6","key":"10.1016\/j.siny.2020.101144_bib30","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.jpeds.2009.12.026","article-title":"Hemodynamics in preterm infants with late-onset sepsis","volume":"156","author":"de Waal","year":"2010","journal-title":"J\u00a0Pediatr"},{"issue":"5","key":"10.1016\/j.siny.2020.101144_bib31","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1097\/PCC.0000000000000115","article-title":"Hemodynamic changes in preterm neonates with septic shock: a prospective observational study\u2217","volume":"15","author":"Saini","year":"2014","journal-title":"Pediatr Crit Care Med"},{"issue":"10","key":"10.1016\/j.siny.2020.101144_bib32","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s00431-002-1042-5","article-title":"The pulse oximeter perfusion index as a predictor for high illness severity in neonates","volume":"161","author":"De Felice","year":"2002","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.siny.2020.101144_bib33","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jpeds.2016.08.008","article-title":"Decreased variability and low values of perfusion index on day one are associated with adverse outcome in extremely preterm infants","volume":"178","author":"Van Laere","year":"2016","journal-title":"J\u00a0Pediatr"},{"issue":"3","key":"10.1016\/j.siny.2020.101144_bib34","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.earlhumdev.2010.01.031","article-title":"Clinical monitoring of systemic hemodynamics in critically ill newborns","volume":"86","author":"de Boode","year":"2010","journal-title":"Early Hum Dev"},{"issue":"3","key":"10.1016\/j.siny.2020.101144_bib35","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/apa.12906","article-title":"Current research suggests that the future looks brighter for cerebral oxygenation monitoring in preterm infants","volume":"104","author":"Kenosi","year":"2015","journal-title":"Acta Paediatr"},{"key":"10.1016\/j.siny.2020.101144_bib36","doi-asserted-by":"crossref","first-page":"g7635","DOI":"10.1136\/bmj.g7635","article-title":"Cerebral near infrared spectroscopy oximetry in extremely preterm infants: phase II randomised clinical trial","volume":"350","author":"Hyttel-Sorensen","year":"2015","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.siny.2020.101144_bib37","doi-asserted-by":"crossref","first-page":"F86","DOI":"10.1136\/adc.2010.189142","article-title":"Functional cardiac MRI in preterm and term newborns","volume":"96","author":"Groves","year":"2011","journal-title":"Arch Dis Child Fetal Neonatal Ed"}],"container-title":["Seminars in Fetal and Neonatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744165X2030069X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1744165X2030069X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:44:04Z","timestamp":1761677044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1744165X2030069X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["S1744165X2030069X"],"URL":"https:\/\/doi.org\/10.1016\/j.siny.2020.101144","relation":{},"ISSN":["1744-165X"],"issn-type":[{"value":"1744-165X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of neonatal perfusion","name":"articletitle","label":"Article Title"},{"value":"Seminars in Fetal and Neonatal Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.siny.2020.101144","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101144"}}