{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:12:56Z","timestamp":1791231176629,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,20]],"date-time":"2016-10-20T00:00:00Z","timestamp":1476921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Saudi Journal of Biological Sciences"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.sjbs.2016.10.015","type":"journal-article","created":{"date-parts":[[2016,10,25]],"date-time":"2016-10-25T02:30:40Z","timestamp":1477362640000},"page":"1263-1271","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["The utility of inflammation and platelet biomarkers in patients with acute coronary syndromes"],"prefix":"10.1016","volume":"25","author":[{"given":"Joanna","family":"Kami\u0144ska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga M.","family":"Koper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edyta","family":"Siedlecka-Czykier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna","family":"Matowicka-Karna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Bychowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halina","family":"Kemona","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.sjbs.2016.10.015_b0005","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1161\/CIRCULATIONAHA.111.047431","article-title":"Acute coronary events","volume":"125","author":"Arbab-Zadeh","year":"2012","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.sjbs.2016.10.015_b0010","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/BF00276813","article-title":"Plasma beta-thromboglobulin in diabetes mellitus","volume":"18","author":"Borsey","year":"1980","journal-title":"Diabetologia"},{"issue":"5","key":"10.1016\/j.sjbs.2016.10.015_b0015","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1161\/ATVBAHA.107.161471","article-title":"Tissue factor in patients with acute coronary syndromes: expression in platelets, leukocytes, and platelet-leukocyte aggregates","volume":"28","author":"Brambilla","year":"2008","journal-title":"Arterioscler Thromb Vasc. Biol."},{"key":"10.1016\/j.sjbs.2016.10.015_b0020","unstructured":"Bychowski, J., 2002. Ocena wybranych parametr\u00f3w aktywacji p\u0142ytek krwi u chorych z niestabiln\u0105 d\u0142awic\u0105 piersiow\u0105. Doctoral Thesis. Bia\u0142ystok."},{"issue":"10","key":"10.1016\/j.sjbs.2016.10.015_b0025","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.biopha.2009.06.004","article-title":"Inflammatory markers and cardiac function in acute coronary syndrome: difference in ST-segment elevation myocardial infarction (STEMI) and in non-STEMI models","volume":"63","author":"Di Stefano","year":"2009","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.sjbs.2016.10.015_b0030","first-page":"21","article-title":"Biomarkers in the prediction and management of acute coronary syndromes: current perspectives","volume":"5","author":"Gilardi","year":"2014","journal-title":"Res. Rep. Clin. Cardiol."},{"issue":"3","key":"10.1016\/j.sjbs.2016.10.015_b0035","first-page":"e28","article-title":"American heart association statistics committee and stroke statistics subcommittee. Heart disease and stroke statistics-2013 Update: a report from the American Heart Association","volume":"129","author":"Go","year":"2014","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.sjbs.2016.10.015_b0040","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1590\/S0066-782X2010005000161","article-title":"CRP levels are higher in patients with ST elevation than non-ST elevation acute coronary syndrome","volume":"96","author":"Habib","year":"2011","journal-title":"Arq. Bras. Cardiol."},{"issue":"16","key":"10.1016\/j.sjbs.2016.10.015_b0045","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJMra043430","article-title":"Inflammation, atherosclerosis, and coronary artery disease","volume":"352","author":"Hansson","year":"2005","journal-title":"N Engl. J. Med."},{"issue":"12","key":"10.1016\/j.sjbs.2016.10.015_b0050","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1056\/NEJMoa022600","article-title":"CAPTURE Study Investigators. Soluble CD40 ligand in acute coronary syndromes","volume":"348","author":"Heeschen","year":"2003","journal-title":"N. Engl. J. Med."},{"issue":"2","key":"10.1016\/j.sjbs.2016.10.015_b0055","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jacc.2004.09.060","article-title":"CAPTURE Study Investigators. Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis","volume":"45","author":"Heeschen","year":"2005","journal-title":"J. Am. Coll. Cardiol."},{"issue":"5","key":"10.1016\/j.sjbs.2016.10.015_b0060","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1161\/CIRCRESAHA.115.305919","article-title":"Myocardial infarction and inflammation: lost in the biomarker labyrinth","volume":"116","author":"Hristov","year":"2015","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.sjbs.2016.10.015_b0065","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1182\/blood.V57.2.199.199","article-title":"Plasma levels of beta-thromboglobulin and platelet factor 4 as indices of platelet activation in vivo","volume":"57","author":"Kaplan","year":"1981","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.sjbs.2016.10.015_b0070","article-title":"Could mean platelet volume be a predictive marker for acute myocardial infarction?","volume":"11","author":"Kili\u00e7li-Camur","year":"2005","journal-title":"Med. Sci. Monit."},{"issue":"1","key":"10.1016\/j.sjbs.2016.10.015_b0075","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1538-7836.2010.04110.x","article-title":"High platelet volume and increased risk of myocardial infarction: 39,531 participants from the general population","volume":"9","author":"Klovaite","year":"2011","journal-title":"J. Thromb. Haemost."},{"issue":"16","key":"10.1016\/j.sjbs.2016.10.015_b0080","first-page":"2452","article-title":"Relationship between coronary atherosclerosis plaque characteristics and high sensitivity C-reactive proteins, interleukin-6","volume":"124","author":"Lai","year":"2011","journal-title":"Chin. Med. J."},{"issue":"16","key":"10.1016\/j.sjbs.2016.10.015_b0085","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1056\/NEJM200010193431602","article-title":"Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. FRISC Study Group. Fragmin during Instability in Coronary Artery Disease","volume":"343","author":"Lindahl","year":"2000","journal-title":"N. Engl. J. Med."},{"issue":"6","key":"10.1016\/j.sjbs.2016.10.015_b0090","doi-asserted-by":"crossref","first-page":"e164","DOI":"10.1016\/S0828-282X(09)70090-X","article-title":"Relationship of admission hematological indexes with myocardial reperfusion abnormalities in acute ST segment elevation myocardial infarction patients treated with primary percutaneous coronary interventions","volume":"25","author":"Maden","year":"2009","journal-title":"Can. J. Cardiol."},{"issue":"8780","key":"10.1016\/j.sjbs.2016.10.015_b0095","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1016\/0140-6736(91)92719-I","article-title":"Influence of platelet size on outcome after myocardial infarction","volume":"338","author":"Martin","year":"1991","journal-title":"Lancet"},{"issue":"6","key":"10.1016\/j.sjbs.2016.10.015_b0100","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1055\/s-0037-1615952","article-title":"Platelet reactivity in acute coronary syndromes: evidence for differences in platelet behaviour between unstable angina and myocardial infarction","volume":"85","author":"Mathur","year":"2001","journal-title":"Thromb. Haemost."},{"issue":"13","key":"10.1016\/j.sjbs.2016.10.015_b0105","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1161\/hc3801.095588","article-title":"Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction","volume":"104","author":"Michelson","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.sjbs.2016.10.015_b0110","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3389\/fimmu.2015.00098","article-title":"Platelets in inflammation and atherogenesis","volume":"6","author":"Nording","year":"2015","journal-title":"Front. Immunol."},{"issue":"8","key":"10.1016\/j.sjbs.2016.10.015_b0115","article-title":"Mean platelet volume in patients with acute coronary syndromes: a supportive diagnostic predictor","volume":"8","author":"Pal","year":"2014","journal-title":"J Clin Diagn Res."},{"issue":"10","key":"10.1016\/j.sjbs.2016.10.015_b0120","doi-asserted-by":"crossref","first-page":"e13404","DOI":"10.1371\/journal.pone.0013404","article-title":"Proteins involved in platelet signaling are differentially regulated in acute coronary syndrome: a proteomic study","volume":"5","author":"Pargui\u00f1a","year":"2010","journal-title":"PLoS ONE"},{"issue":"8","key":"10.1016\/j.sjbs.2016.10.015_b0125","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1161\/ATVBAHA.107.145987","article-title":"Relationship between a systemic inflammatory marker, plaque inflammation, and plaque characteristics determined by intravascular optical coherence tomography","volume":"27","author":"Raffel","year":"2007","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"issue":"11","key":"10.1016\/j.sjbs.2016.10.015_b0130","first-page":"739","article-title":"Mean platelet volume in diabetes mellitus","volume":"86","author":"Sharpe","year":"1993","journal-title":"Q. J. Med."},{"issue":"5","key":"10.1016\/j.sjbs.2016.10.015_b0135","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1161\/ATVBAHA.110.221788","article-title":"Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease","volume":"31","author":"Slavka","year":"2011","journal-title":"Arterioscler Thromb. Vasc. Biol."},{"issue":"3","key":"10.1016\/j.sjbs.2016.10.015_b0140","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/0002-9149(81)90065-5","article-title":"Elevated beta thromboglobulin in peripheral venous blood of patients with acute myocardial ischemia: direct evidence for enhanced platelet reactivity in vivo","volume":"48","author":"Smitherman","year":"1981","journal-title":"Am. J. Cardiol."},{"issue":"4","key":"10.1016\/j.sjbs.2016.10.015_b0145","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1177\/039463201402700407","article-title":"Role of mast cells in atherosclerosis: a classical inflammatory disease","volume":"27","author":"Spinas","year":"2014","journal-title":"Int. J. Immunopathol. Pharmacol."},{"issue":"7","key":"10.1016\/j.sjbs.2016.10.015_b0150","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.amjcard.2006.11.032","article-title":"Inflammatory markers, angiographic severity of coronary artery disease, and patient outcome","volume":"99","author":"Sukhija","year":"2007","journal-title":"Am. J. Cardiol."},{"issue":"9","key":"10.1016\/j.sjbs.2016.10.015_b0155","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/clc.20254","article-title":"Clinical implications of elevated serum interleukin-6, soluble CD40 ligand, metalloproteinase-9, and tissue inhibitor of metalloproteinase-1 in patients with acute ST-segment elevation myocardial infarction","volume":"31","author":"Tan","year":"2008","journal-title":"Clin. Cardiol."},{"key":"10.1016\/j.sjbs.2016.10.015_b0160","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2174\/1874192401105010110","article-title":"Relationship between MMP-1, MMP-9, TIMP-1, IL-6 and risk factors, clinical presentation, extent and severity of atherosclerotic coronary artery disease","volume":"5","author":"Tanindi","year":"2011","journal-title":"Open. Cardiovasc. Med. J."},{"issue":"11","key":"10.1016\/j.sjbs.2016.10.015_b0165","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.5603\/KP.2013.0293","article-title":"The relationship between platelet indices and clinical features of coronary artery disease","volume":"71","author":"Turk","year":"2013","journal-title":"Kardiol. Pol."},{"issue":"8","key":"10.1016\/j.sjbs.2016.10.015_b0170","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1177\/1076029612467845","article-title":"Elevated RANTES level is associated with metabolic syndrome and correlated with activated platelets associated markers in healthy younger men","volume":"20","author":"Ueba","year":"2014","journal-title":"Clin. Appl. Thromb. Hemost."},{"issue":"2","key":"10.1016\/j.sjbs.2016.10.015_b0175","doi-asserted-by":"crossref","first-page":"4260","DOI":"10.4238\/2014.June.9.11","article-title":"Correlation of serum high-sensitivity C-reactive protein and interleukin-6 in patients with acute coronary syndrome","volume":"13","author":"Wang","year":"2014","journal-title":"Genet. Mol. Res."},{"issue":"3","key":"10.1016\/j.sjbs.2016.10.015_b0180","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.psym.2013.09.004","article-title":"Do platelet-derived microparticles play a role in depression, inflammation, and acute coronary syndrome?","volume":"55","author":"Williams","year":"2014","journal-title":"Psychosomatics"},{"issue":"1","key":"10.1016\/j.sjbs.2016.10.015_b0185","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s11239-007-0078-9","article-title":"Role of mean platelet volume in triagging acute coronary syndromes","volume":"26","author":"Yilmaz","year":"2008","journal-title":"J. Thromb. Thrombolysis."},{"issue":"1","key":"10.1016\/j.sjbs.2016.10.015_b0190","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/clc.2","article-title":"Association of platelet-monocyte aggregates with platelet activation, systemic inflammation, and myocardial injury in patients with non-st elevation acute coronary syndromes","volume":"30","author":"Zhang","year":"2007","journal-title":"Clin. Cardiol."}],"container-title":["Saudi Journal of Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X16301395?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X16301395?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T04:31:38Z","timestamp":1657513898000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1319562X16301395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":38,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S1319562X16301395"],"URL":"https:\/\/doi.org\/10.1016\/j.sjbs.2016.10.015","relation":{},"ISSN":["1319-562X"],"issn-type":[{"value":"1319-562X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The utility of inflammation and platelet biomarkers in patients with acute coronary syndromes","name":"articletitle","label":"Article Title"},{"value":"Saudi Journal of Biological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sjbs.2016.10.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}