{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:15:10Z","timestamp":1791000910490,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T00:00:00Z","timestamp":1519603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Saudi Journal of Biological Sciences"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.sjbs.2018.02.016","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T08:38:06Z","timestamp":1519720686000},"page":"1095-1100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Gastric cancer & prospects of cancer in Saudi Arabia peninsula"],"prefix":"10.1016","volume":"26","author":[{"given":"Abdulwahab Ali","family":"Abuderman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sjbs.2018.02.016_b0005","doi-asserted-by":"crossref","unstructured":"Al Saghier, A., Kabanja, J.H., Afreen, S., Sagar, M., 2013. Gastric cancer: environmental risk factors, treatment and prevention. J. Carcinogene Mutagene S14:008 http:\/\/doi.org\/10.4172\/2157-2518.S14-008.","DOI":"10.4172\/2157-2518.S14-008"},{"issue":"2","key":"10.1016\/j.sjbs.2018.02.016_b0010","first-page":"606","article-title":"Incidence of gastric carcinoma at King Faisal Specialist Hospital \u2013 Jeddah Saudi Arabia: a hospital-based study Integr","volume":"3","author":"Alahmadi","year":"2016","journal-title":"Mol. Med."},{"key":"10.1016\/j.sjbs.2018.02.016_b0015","doi-asserted-by":"crossref","unstructured":"Alhussaini, M.S., 2016. Prevalence of Helicobacter pylori among patients with different gastrointestinal disorders in Saudi Arabia. Med. J. Indonesia 25(4) https:\/\/doi.org\/10.13181\/mji.v25i4.1442.","DOI":"10.13181\/mji.v25i4.1442"},{"issue":"4","key":"10.1016\/j.sjbs.2018.02.016_b0020","doi-asserted-by":"crossref","first-page":"258","DOI":"10.5001\/omj.2011.62","article-title":"K Sharples Incidence of stomach cancer in Oman and other Gulf Cooperation Council countries","volume":"26","author":"Al-Mahrouqi","year":"2011","journal-title":"Oman Med. J."},{"key":"10.1016\/j.sjbs.2018.02.016_b0025","unstructured":"Al-Samawi, Aulaqi, 2012. Histopathology of gastric cancer in Yemen: a 7 years retrospective analysis, Sudan. JMS 7(4), 95\u201397."},{"issue":"9","key":"10.1016\/j.sjbs.2018.02.016_b0030","doi-asserted-by":"crossref","first-page":"674","DOI":"10.7439\/ijbr.v6i9.2457","article-title":"Epidemiological indicators of cancer in north Saudi Arabia: a population-based survey","volume":"6","author":"Alshammari","year":"2015","journal-title":"Int. J. Biomed. Res."},{"key":"10.1016\/j.sjbs.2018.02.016_b0035","doi-asserted-by":"crossref","unstructured":"Berretta, M., Cappellani, A., Lleshi, A., Di Vita, M., Lo Menzo, E., et al., 2012. The role of diet in gastric cancer: still an open question. Front. Biosci. 17, 1640\u20131647.","DOI":"10.2741\/4009"},{"key":"10.1016\/j.sjbs.2018.02.016_b0040","doi-asserted-by":"crossref","unstructured":"Buckland, G., Agudo, A., Lujan, L., Jakszyn, P., Bueno-de-Mesquita, H.B., Palli, D., et al., 2010. Adherence to a mediterranean diet and risk of gastric adenocarcinoma within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study. Am. J. Clin. Nutri. 91(2), 381\u2013390.","DOI":"10.3945\/ajcn.2009.28209"},{"key":"10.1016\/j.sjbs.2018.02.016_b0045","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ctrv.2012.09.007","article-title":"Current questions for the treatment of advanced gastric cancer","volume":"39","author":"Cervantes","year":"2013","journal-title":"Cancer Treat. Rev."},{"key":"10.1016\/j.sjbs.2018.02.016_b0050","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0140-6736(75)90498-5","article-title":"A model for gastric cancer epidemiology","volume":"2","author":"Correa","year":"1975","journal-title":"Lancet"},{"key":"10.1016\/j.sjbs.2018.02.016_b0055","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.gtc.2013.01.003","article-title":"Gastric cancer: epidemiology and risk factors","volume":"42","author":"de Martel","year":"2013","journal-title":"Gastroenterol. Clin. North Am."},{"key":"10.1016\/j.sjbs.2018.02.016_b0060","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/01.sla.0000149300.28588.23","article-title":"et al Gastric adenocarcinoma: review and considerations for future directions","volume":"241","author":"Dicken","year":"2005","journal-title":"Ann Surg."},{"key":"10.1016\/j.sjbs.2018.02.016_b0065","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.ejca.2012.12.027","article-title":"Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012","volume":"49","author":"Ferlay","year":"2013","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.sjbs.2018.02.016_b0070","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.ejca.2014.01.029","article-title":"Worldwide trends in gastric cancer mortality (1980\u20132011), with predictions to 2015, and incidence by subtype","volume":"50","author":"Ferro","year":"2014","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.sjbs.2018.02.016_b0075","doi-asserted-by":"crossref","unstructured":"Fitzsimmons, D., Osmond, C., George, S., Johnson, C.D., 2007. Trends in stomach and pancreatic cancer incidence and mortality in England and Wales, 1951\u20132000. Br J Surg 94(9), 1162.","DOI":"10.1002\/bjs.5751"},{"key":"10.1016\/j.sjbs.2018.02.016_b0080","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/nar\/gkq929","article-title":"COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer","volume":"39","author":"Forbes","year":"2011","journal-title":"Nucl. Acids Res."},{"key":"10.1016\/j.sjbs.2018.02.016_b0085","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0140-6736(08)61159-9","article-title":"Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial","volume":"372","author":"Fukase","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.sjbs.2018.02.016_b0090","doi-asserted-by":"crossref","unstructured":"Ge, S., Feng, X., Shen, L., Wei, Z., Zhu, Q., et al., 2012. Association between habitual dietary salt intake and risk of gastric cancer: a systematic review of observational studies. Gastroenterol. Res. Pract. 2012, 808120.","DOI":"10.1155\/2012\/808120"},{"key":"10.1016\/j.sjbs.2018.02.016_b0095","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3109\/00365520903401959","article-title":"Helicobacter pylori, nutrition and smoking interactions: their impact in gastric carcinogenesis","volume":"45","author":"Gonzalez","year":"2010","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.sjbs.2018.02.016_b0100","doi-asserted-by":"crossref","first-page":"2910","DOI":"10.1002\/ijc.27565","article-title":"Fruit and vegetable intake and the risk of gastric adenocarcinoma: a reanalysis of the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study after a longer follow-up","volume":"131","author":"Gonzalez","year":"2012","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.sjbs.2018.02.016_b0105","doi-asserted-by":"crossref","unstructured":"Hamdi, J., Morad, N.A., 1994. Gastric cancer in southern Saudi Arabia. Ann. Saudi Med. 14(3), 195\u2013197.","DOI":"10.5144\/0256-4947.1994.195"},{"key":"10.1016\/j.sjbs.2018.02.016_b0110","doi-asserted-by":"crossref","unstructured":"Hasosah, M., Satti, M., Shehzad, A., Alsahafi, A., Sukkar, G., Alzaben, A., Sunaid, A., Ahmed, A., AlThubiti, S., Mufti, A., Jacobson, K., 2015. Prevalence and risk factors of Helicobacter pylori infection in Saudi children: a three-year prospective controlled study. Helicobacter 20(1), 56\u201363. https:\/\/www.cancer.org\/cancer\/stomach-cancer\/about\/key-statistics.html, https:\/\/www.uptodate.com\/contents\/epidemiology-of-gastric-cancer.","DOI":"10.1111\/hel.12172"},{"issue":"26","key":"10.1016\/j.sjbs.2018.02.016_b0115","doi-asserted-by":"crossref","first-page":"3226","DOI":"10.3748\/wjg.v16.i26.3226","article-title":"Helicobacter pylori and gastric cancer in the Middle East: a new enigma?","volume":"16","author":"Hussein","year":"2010","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.sjbs.2018.02.016_b0120","first-page":"14296","article-title":"Nitrosamine and related food intake and gastric and oesophageal cancer risk: a systemic review of the epidemiological evidence","volume":"2","author":"Jakszyn","year":"2006","journal-title":"World J. Gastroenterol."},{"issue":"12","key":"10.1016\/j.sjbs.2018.02.016_b0125","first-page":"1529","article-title":"Saudi Oncology Society clinical management guideline series","volume":"35","author":"Kandil","year":"2014","journal-title":"Saudi Med. J."},{"key":"10.1016\/j.sjbs.2018.02.016_b0130","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1158\/1055-9965.EPI-13-1057","article-title":"Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention","volume":"23","author":"Karimi","year":"2014","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.sjbs.2018.02.016_b0135","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1002\/bjs.6944","article-title":"Long term outcome after proximal gastrectomy with jejunal interposition for suspected early cancer in the upper third of the stomach","volume":"97","author":"Katai","year":"2010","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.sjbs.2018.02.016_b0140","doi-asserted-by":"crossref","unstructured":"Kumar, R.K., Raj, S.S., Shankar, E.M., Ganapathy, E., Ebrahim, A.S., Farooq, S.M., 2013. Gastric Carcinoma: A Review on Epidemiology, Current Surgical and Chemotherapeutic Options. Intech Open, pp. 271\u2013293 (Chapter 12) https:\/\/doi.org\/10.5772\/45896.","DOI":"10.5772\/45896"},{"key":"10.1016\/j.sjbs.2018.02.016_b0145","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1753-4887.2008.00029.x","article-title":"Nutrition and gastric cancer risk: an update","volume":"66","author":"Liu","year":"2008","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.sjbs.2018.02.016_b0150","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/01.cej.0000236255.95769.22","article-title":"Fruit and vegetable consumption and gastric cancer by location and histological type: case-control and meta-analysis","volume":"16","author":"Lunet","year":"2007","journal-title":"Eur. J. Cancer Prev."},{"key":"10.1016\/j.sjbs.2018.02.016_b0155","series-title":"Cancer Incidence In Oman, 2007","author":"Mohammad","year":"2009"},{"key":"10.1016\/j.sjbs.2018.02.016_b0160","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1056\/NEJMoa010187","article-title":"Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction","volume":"345","author":"Macdonald","year":"2001","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.sjbs.2018.02.016_b0165","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.bpg.2006.10.005","article-title":"Epidemiology of Helicobacter pylori infection","volume":"21","author":"Malaty","year":"2007","journal-title":"Best Prac. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.sjbs.2018.02.016_b0170","doi-asserted-by":"crossref","first-page":"2287","DOI":"10.1158\/1055-9965.EPI-10-0362","article-title":"et al Alcohol and tobacco use in relation to gastric cancer: a prospective study of men in Shanghai, China","volume":"19","author":"Moy","year":"2010","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.sjbs.2018.02.016_b0175","doi-asserted-by":"crossref","first-page":"156","DOI":"10.4251\/wjgo.v4.i7.156","article-title":"Carcinoma of the stomach: a review of epidemiology, pathogenesis, molecular genetics and chemoprevention","volume":"4","author":"Nagini","year":"2012","journal-title":"World J. Gastrointest. Oncol."},{"issue":"4","key":"10.1016\/j.sjbs.2018.02.016_b0180","first-page":"175","article-title":"Evaluation of circulating TP53 antigen in the sera of gastric cancer patients: as a tumor marker Biomark","volume":"5","author":"Nasif","year":"2013","journal-title":"Genomic Med."},{"key":"10.1016\/j.sjbs.2018.02.016_b0185","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1111\/j.1349-7006.2002.tb01209.x","article-title":"Synergistic Promoting effects of Helicobacter pylori infection and high-salt diet on gastric carcinogenesis in mongolian gerbils","volume":"93","author":"Nozaki","year":"2002","journal-title":"Jpn. J. Cancer Res."},{"key":"10.1016\/j.sjbs.2018.02.016_b0190","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S1286-4579(03)00111-4","article-title":"Burden of Helicobacter pylori and H. pylori-related diseases in developed countries: recent developments and future implications","volume":"5","author":"Rothenbacher","year":"2003","journal-title":"Microbes Infect."},{"key":"10.1016\/j.sjbs.2018.02.016_b0195","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/ijc.28344","article-title":"Neglected role of hookah and opium in gastric carcinogenesis: a cohort study on risk factors and attributable fractions","volume":"134","author":"Sadjadi","year":"2014","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.sjbs.2018.02.016_b0200","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1007\/s10120-015-0479-y","article-title":"Endoscopic and histological features of gastric cancers after successful Helicobacter pylori eradication therapy","volume":"19","author":"Saka","year":"2016","journal-title":"Gastric Cancer"},{"key":"10.1016\/j.sjbs.2018.02.016_b0205","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4103\/1319-3767.54743","article-title":"Helicobacter pylori infection in developing countries. The burden for how long?","volume":"15","author":"Salih","year":"2009","journal-title":"Saudi J. Gastroenterol."},{"key":"10.1016\/j.sjbs.2018.02.016_b0210","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1349-7006.2003.tb01450.x","article-title":"The effect of 5-year vitamin C supplementation on serum pepsinogen level and Helicobacter pylori infection","volume":"94","author":"Sasazuki","year":"2003","journal-title":"Cancer Sci."},{"key":"10.1016\/j.sjbs.2018.02.016_b0215","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1093\/aje\/kwn276","article-title":"et al Population-based prospective study of the combined influence of cigarette smoking ahd Helicobacter pylori infection on gastric cancer incidence: the Hisayama study","volume":"168","author":"Shikata","year":"2008","journal-title":"Am. J. Epidemiol."},{"issue":"1","key":"10.1016\/j.sjbs.2018.02.016_b0220","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3322\/caac.21208","article-title":"Cancer statistics, 2014","volume":"64","author":"Siegel","year":"2014","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.sjbs.2018.02.016_b0225","doi-asserted-by":"crossref","unstructured":"Siegel, R.L., Miller, K.D., Jemal, A., 2017. Cancer statistics 2017 CA 67(1). http:\/\/doi.org\/10.3322\/caac.21387.","DOI":"10.3322\/caac.21387"},{"key":"10.1016\/j.sjbs.2018.02.016_b0230","first-page":"705","article-title":"Dietary habits and gastro-intestinal cancers: a comparative case-control study of stomach and large intestinal cancers in Nagoya, Japan","volume":"76","author":"Tajima","year":"1985","journal-title":"Jpn. J. Cancer Res."},{"issue":"11","key":"10.1016\/j.sjbs.2018.02.016_b0235","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1093\/jjco\/hyx128","article-title":"Estimation of lifetime cumulative incidence and mortality risk of gastric cancer","volume":"47","author":"Taniyama","year":"2017","journal-title":"Jpn. J. Clin. Oncol."},{"key":"10.1016\/j.sjbs.2018.02.016_b0240","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms18081699","article-title":"Prevention of gastric cancer: eradication of Helicobacter pylori and beyond","volume":"18","author":"Tsukamoto","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.sjbs.2018.02.016_b0245","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1056\/NEJMoa001999","article-title":"Helicobacter pylori infection and the development of gastric cancer","volume":"345","author":"Uemura","year":"2001","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.sjbs.2018.02.016_b0250","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1200\/JCO.2005.05.0245","article-title":"Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data","volume":"24","author":"Wagner","year":"2006","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.sjbs.2018.02.016_b0255","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1023\/A:1018833819860","article-title":"et al Helicobacter pylori infection and gastric cancer. A nested case-control study in a rural area of Japan","volume":"42","author":"Watanabe","year":"1997","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.sjbs.2018.02.016_b0260","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1038\/sj.bjc.6602067","article-title":"Individual and joint impact of family history and Helicobacter pylori infection on the risk of stomach cancer: a nested case-control study","volume":"91","author":"Yatsuya","year":"2004","journal-title":"Br J Cancer"},{"issue":"2017","key":"10.1016\/j.sjbs.2018.02.016_b0265","first-page":"66","article-title":"Estimates of cancer incidence and mortality in China","volume":"36","author":"Zheng","year":"2013","journal-title":"Chin. J. Cancer"}],"container-title":["Saudi Journal of Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X18300512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X18300512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T19:23:14Z","timestamp":1603912994000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1319562X18300512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":53,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S1319562X18300512"],"URL":"https:\/\/doi.org\/10.1016\/j.sjbs.2018.02.016","relation":{},"ISSN":["1319-562X"],"issn-type":[{"value":"1319-562X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gastric cancer & prospectsof cancer in Saudi Arabia peninsula","name":"articletitle","label":"Article Title"},{"value":"Saudi Journal of Biological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sjbs.2018.02.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Production and hosting by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}