{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T07:08:11Z","timestamp":1786950491060,"version":"build-2736575974"},"reference-count":58,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,22]],"date-time":"2021-01-22T00:00:00Z","timestamp":1611273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007614","name":"Al Jouf University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007614","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Saudi Journal of Biological Sciences"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.sjbs.2021.01.051","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T11:09:53Z","timestamp":1611918593000},"page":"2502-2509","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Computational drug screening against the SARS-CoV-2 Saudi Arabia isolates through a multiple-sequence alignment approach"],"prefix":"10.1016","volume":"28","author":[{"given":"Pooi Ling","family":"Mok","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avin Ee-Hwan","family":"Koh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aisha","family":"Farhana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Alsrhani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Khursheed","family":"Alam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subbiah","family":"Suresh Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sjbs.2021.01.051_b0005","article-title":"Amantadine as a drug to mitigate the effects of COVID-19","volume":"140","author":"Abreu","year":"2020","journal-title":"Med. Hypotheses"},{"issue":"June","key":"10.1016\/j.sjbs.2021.01.051_b0010","article-title":"Preparedness and response to COVID-19 in Saudi Arabia: building on MERS experience","author":"Algaissi","year":"2020","journal-title":"J. Infect. Public Health"},{"key":"10.1016\/j.sjbs.2021.01.051_b0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.arcmed.2020.06.009","article-title":"Amantadine treatment for people with COVID-19","author":"Ara\u00fajo","year":"2020","journal-title":"Arch. Med. Res."},{"issue":"W1","key":"10.1016\/j.sjbs.2021.01.051_b0020","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gks400","article-title":"ExPASy: SIB bioinformatics resource portal","volume":"40","author":"Artimo","year":"2012","journal-title":"Nucleic Acids Res."},{"issue":"March","key":"10.1016\/j.sjbs.2021.01.051_b0025","article-title":"The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds","author":"B\u00e1ez-Santos","year":"2015","journal-title":"Antiviral Res."},{"issue":"1","key":"10.1016\/j.sjbs.2021.01.051_b0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2991\/jegh.k.200218.003","article-title":"Covid-19 in the shadows of MERS-CoV in the Kingdom of Saudi Arabia","volume":"10","author":"Barry","year":"2020","journal-title":"J. Epidemiol. Global Health"},{"key":"10.1016\/j.sjbs.2021.01.051_b0035","doi-asserted-by":"crossref","unstructured":"Bharath, B.R., Damle, H., Ganju, S., Damle, L., 2020. In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19. F1000Research 9. https:\/\/doi.org\/10.12688\/f1000research.24143.1.","DOI":"10.12688\/f1000research.24143.1"},{"issue":"December","key":"10.1016\/j.sjbs.2021.01.051_b0040","article-title":"Is the discovery of the novel human betacoronavirus 2c EMC\/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?","author":"Chan","year":"2012","journal-title":"J. Infect."},{"key":"10.1016\/j.sjbs.2021.01.051_b0045","doi-asserted-by":"crossref","unstructured":"De Vries, M., Mohamed, A. S., Prescott, R. A., Valero-Jimenez, A. M., Desvignes, L., O\u2019connor, R., et al., 2020. Comparative study of a 3CL pro inhibitor and remdesivir against both major SARS-1 CoV-2 clades in human airway models 2 3. BioRxiv, 2020.08.28.272880. https:\/\/doi.org\/10.1101\/2020.08.28.272880.","DOI":"10.1101\/2020.08.28.272880"},{"key":"10.1016\/j.sjbs.2021.01.051_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/S0140-6736(20)30466-9","article-title":"COVID-19: preparing for superspreader potential among Umrah pilgrims to Saudi Arabia","author":"Ebrahim","year":"2020","journal-title":"The Lancet"},{"key":"10.1016\/j.sjbs.2021.01.051_b0055","doi-asserted-by":"crossref","unstructured":"Fogel, D.B., 2018, September 1. Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: a review. Contemp. Clin. Trials Commun. https:\/\/doi.org\/10.1016\/j.conctc.2018.08.001.","DOI":"10.1016\/j.conctc.2018.08.001"},{"key":"10.1016\/j.sjbs.2021.01.051_b0060","article-title":"Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency","author":"Gordon","year":"2020","journal-title":"J. Biol. Chem. Am. Soc. Biochem. Mol. Biol."},{"issue":"12","key":"10.1016\/j.sjbs.2021.01.051_b0065","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1001\/jamainternmed.2016.6008","article-title":"Failure of investigational drugs in late-stage clinical development and publication of trial results","volume":"176","author":"Hwang","year":"2016","journal-title":"JAMA Internal Med."},{"key":"10.1016\/j.sjbs.2021.01.051_b0070","doi-asserted-by":"crossref","unstructured":"Irwin, J.J., Sterling, T., Mysinger, M.M., Bolstad, E.S., Coleman, R.G., 2012, July 23. ZINC: A free tool to discover chemistry for biology. J. Chem. Inform. Model. https:\/\/doi.org\/10.1021\/ci3001277.","DOI":"10.1021\/ci3001277"},{"key":"10.1016\/j.sjbs.2021.01.051_b0075","doi-asserted-by":"crossref","unstructured":"Jarada, T.N., Rokne, J.G., Alhajj, R., 2020, July 22. A review of computational drug repositioning: Strategies, approaches, opportunities, challenges, and directions. J. Cheminformatics. BioMed Central. https:\/\/doi.org\/10.1186\/s13321-020-00450-7.","DOI":"10.1186\/s13321-020-00450-7"},{"key":"10.1016\/j.sjbs.2021.01.051_b0080","article-title":"Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of RBD mutant with lower ACE2 binding affinity","author":"Jia","year":"2020","journal-title":"BioRxiv"},{"key":"10.1016\/j.sjbs.2021.01.051_b0085","doi-asserted-by":"crossref","unstructured":"Jiang, Z., Gao, W., Huang, L., 2019, March 14. Tanshinones, critical pharmacological components in salvia miltiorrhiza. Front. Pharmacol. https:\/\/doi.org\/10.3389\/fphar.2019.00202.","DOI":"10.3389\/fphar.2019.00202"},{"issue":"1","key":"10.1016\/j.sjbs.2021.01.051_b0090","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1080\/14756366.2020.1801672","article-title":"Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro","volume":"35","author":"Jo","year":"2020","journal-title":"J. Enzyme Inhibition Med. Chem."},{"issue":"1","key":"10.1016\/j.sjbs.2021.01.051_b0095","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1080\/14756366.2019.1690480","article-title":"Inhibition of SARS-CoV 3CL protease by flavonoids","volume":"35","author":"Jo","year":"2020","journal-title":"J. Enzyme Inhibition Med. Chem."},{"key":"10.1016\/j.sjbs.2021.01.051_b0100","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.virol.2020.08.010","article-title":"Quantitative phylogenomic evidence reveals a spatially structured SARS-CoV-2 diversity","volume":"550","author":"Jones","year":"2020","journal-title":"Virology"},{"issue":"8","key":"10.1016\/j.sjbs.2021.01.051_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e04642","article-title":"Virtual screening, molecular docking studies and DFT calculations of FDA approved compounds similar to the non-nucleoside reverse transcriptase inhibitor (NNRTI) efavirenz","volume":"6","author":"Jordaan","year":"2020","journal-title":"Heliyon"},{"issue":"6","key":"10.1016\/j.sjbs.2021.01.051_b0110","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/jmv.25754","article-title":"From SARS and MERS CoVs to SARS-CoV-2: moving toward more biased codon usage in viral structural and nonstructural genes","volume":"92","author":"Kandeel","year":"2020","journal-title":"J. Med. Virol."},{"issue":"4","key":"10.1016\/j.sjbs.2021.01.051_b0115","doi-asserted-by":"crossref","first-page":"782","DOI":"10.3904\/kjim.2020.157","article-title":"In vitro activity of lopinavir\/ritonavir and hydroxychloroquine against severe acute respiratory syndrome coronavirus 2 at concentrations achievable by usual doses","volume":"35","author":"Kang","year":"2020","journal-title":"The Korean Journal of Internal Medicine"},{"key":"10.1016\/j.sjbs.2021.01.051_b0120","doi-asserted-by":"crossref","unstructured":"Kelleni, M.T., 2020, July 1. Nitazoxanide\/azithromycin combination for COVID-19: A suggested new protocol for early management. Pharmacol. Res. https:\/\/doi.org\/10.1016\/j.phrs.2020.104874.","DOI":"10.20944\/preprints202004.0432.v1"},{"key":"10.1016\/j.sjbs.2021.01.051_b0125","doi-asserted-by":"crossref","unstructured":"Khan, N.T., 2017. MEGA - Core of Phylogenetic Analysis in Molecular Evolutionary Genetics. https:\/\/doi.org\/10.4172\/2329-9002.1000183.","DOI":"10.4172\/2329-9002.1000183"},{"issue":"November","key":"10.1016\/j.sjbs.2021.01.051_b0130","article-title":"Exploring the new horizons of drug repurposing: a vital tool for turning hard work into smart work","author":"Kumar","year":"2019","journal-title":"Eur. J. Med. Chem."},{"issue":"6","key":"10.1016\/j.sjbs.2021.01.051_b0135","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1093\/molbev\/msy096","article-title":"MEGA X: Molecular evolutionary genetics analysis across computing platforms","volume":"35","author":"Kumar","year":"2018","journal-title":"Mol. Biol. Evol."},{"issue":"MAY","key":"10.1016\/j.sjbs.2021.01.051_b0140","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3389\/fphar.2017.00298","article-title":"On the integration of in silico drug design methods for drug repurposing","volume":"8","author":"March-Vila","year":"2017","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.sjbs.2021.01.051_b0145","article-title":"Tale of three seeding patterns of SARS-CoV-2 in Saudi Arabia","author":"Memish","year":"2020","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.sjbs.2021.01.051_b0150","unstructured":"Meo, S.A., Klonoff, D.C., Akram, J., 2020. Efficacy of chloroquine and hydroxychloroquine in the treatment of COVID-19. Eur. Rev. Med. Pharmacol. Sci. https:\/\/doi.org\/10.26355\/eurrev_202004_21038."},{"key":"10.1016\/j.sjbs.2021.01.051_b0155","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.3389\/fmicb.2020.01800","article-title":"Geographic and Genomic Distribution of SARS-CoV-2 Mutations","volume":"11","author":"Mercatelli","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.sjbs.2021.01.051_b0160","doi-asserted-by":"crossref","unstructured":"Naqvi, A.A.T., Fatima, K., Mohammad, T., Fatima, U., Singh, I.K., Singh, A., et al., 2020, October 1. Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: structural genomics approach. Biochim. Biophys. Acta \u2013 Mol. Basis Dis. https:\/\/doi.org\/10.1016\/j.bbadis.2020.165878.","DOI":"10.1016\/j.bbadis.2020.165878"},{"issue":"7","key":"10.1016\/j.sjbs.2021.01.051_b0165","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1525\/abt.2016.78.7.608","article-title":"Using the free program MEGA to build phylogenetic trees from molecular data","volume":"78","author":"Newman","year":"2016","journal-title":"Am. Biol. Teacher"},{"issue":"11","key":"10.1016\/j.sjbs.2021.01.051_b0170","doi-asserted-by":"crossref","DOI":"10.3390\/molecules25112707","article-title":"Potential of flavonoid-inspired phytomedicines against COVID-19.","volume":"25","author":"Ngwa","year":"2020","journal-title":"Molecules (Basel, Switzerland)"},{"issue":"7","key":"10.1016\/j.sjbs.2021.01.051_b0175","doi-asserted-by":"crossref","first-page":"699","DOI":"10.3855\/jidc.13203","article-title":"Containment of COVID-19: the unprecedented response of Saudi Arabia","volume":"14","author":"Obied","year":"2020","journal-title":"J. Infect. Develop. Countries"},{"key":"10.1016\/j.sjbs.2021.01.051_b0180","doi-asserted-by":"crossref","unstructured":"Ou-Yang, S.S., Lu, J.Y., Kong, X.Q., Liang, Z.J., Luo, C., Jiang, H., 2012, September 27. Computational drug discovery. Acta Pharmacol. Sin. https:\/\/doi.org\/10.1038\/aps.2012.109.","DOI":"10.1038\/aps.2012.109"},{"issue":"1","key":"10.1016\/j.sjbs.2021.01.051_b0185","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1186\/s12967-020-02344-6","article-title":"Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant","volume":"18","author":"Pachetti","year":"2020","journal-title":"J. Translat. Med."},{"issue":"3","key":"10.1016\/j.sjbs.2021.01.051_b0190","article-title":"Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2): an update","volume":"12","author":"Pal","year":"2020","journal-title":"Cureus"},{"issue":"19","key":"10.1016\/j.sjbs.2021.01.051_b0195","doi-asserted-by":"crossref","first-page":"5928","DOI":"10.1016\/j.bmc.2012.07.038","article-title":"Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases","volume":"20","author":"Park","year":"2012","journal-title":"Bioorg. Med. Chem."},{"issue":"December","key":"10.1016\/j.sjbs.2021.01.051_b0200","article-title":"Drug repurposing: progress, challenges and recommendations","author":"Pushpakom","year":"2018","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.sjbs.2021.01.051_b0205","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2017726117","article-title":"Low genetic diversity may be an Achilles heel of SARS-CoV-2","author":"Rausch","year":"2020","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"September","key":"10.1016\/j.sjbs.2021.01.051_b0210","article-title":"Roles of flavonoids against coronavirus infection","author":"Russo","year":"2020","journal-title":"Chemico-Biol. Int."},{"issue":"5","key":"10.1016\/j.sjbs.2021.01.051_b0215","first-page":"437","article-title":"Chinese herbal medicine for SARS and SARS-CoV-2 treatment and prevention, encouraging using herbal medicine for COVID-19 outbreak","volume":"70","author":"Shahrajabian","year":"2020","journal-title":"Acta Agriculturae Scandinavica, Sect. B \u2014 Soil & Plant Sci."},{"key":"10.1016\/j.sjbs.2021.01.051_b0220","doi-asserted-by":"crossref","unstructured":"Shu, Y., McCauley, J., 2017, March 30. GISAID: Global initiative on sharing all influenza data \u2013 from vision to reality. Eurosurveillance. European Centre for Disease Prevention and Control (ECDC). https:\/\/doi.org\/10.2807\/1560-7917.ES.2017.22.13.30494.","DOI":"10.2807\/1560-7917.ES.2017.22.13.30494"},{"issue":"August","key":"10.1016\/j.sjbs.2021.01.051_b0225","article-title":"COVID-19 treatment: close to a cure? A rapid review of pharmacotherapies for the novel coronavirus (SARS-CoV-2)","author":"Song","year":"2020","journal-title":"Int. J. Antimicrob. Agents"},{"issue":"3","key":"10.1016\/j.sjbs.2021.01.051_b0230","first-page":"512","article-title":"Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees","volume":"10","author":"Tamura","year":"1993","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.sjbs.2021.01.051_b0235","first-page":"1","article-title":"SARS-CoV-2 genomic variations associated with mortality rate of COVID-19","author":"Toyoshima","year":"2020","journal-title":"J. Human Genet."},{"issue":"6","key":"10.1016\/j.sjbs.2021.01.051_b0240","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00473-12","article-title":"Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans","volume":"3","author":"van Boheemen","year":"2012","journal-title":"MBio"},{"key":"10.1016\/j.sjbs.2021.01.051_b0245","doi-asserted-by":"crossref","unstructured":"Virdi, R.S., Bavisotto, R.V, Hopper, N.C., Frick, D.N., 2020. Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3. BioRxiv\u00a0: The Preprint Server for Biology. https:\/\/doi.org\/10.1101\/2020.07.06.190413.","DOI":"10.1101\/2020.07.06.190413"},{"key":"10.1016\/j.sjbs.2021.01.051_b0250","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1186\/1471-2105-11-451","article-title":"VIGOR, an annotation program for small viral genomes","volume":"11","author":"Wang","year":"2010","journal-title":"BMC Bioinform."},{"key":"10.1016\/j.sjbs.2021.01.051_b0255","unstructured":"Worldometer, n.d. Saudi Arabia Coronavirus: 291,468 Cases and 3,233 Deaths - Worldometer. Retrieved September 10, 2020, from https:\/\/www.worldometers.info\/coronavirus\/country\/saudi-arabia\/."},{"issue":"5","key":"10.1016\/j.sjbs.2021.01.051_b0260","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.apsb.2020.02.008","article-title":"Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods","volume":"10","author":"Wu","year":"2020","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.sjbs.2021.01.051_b0265","doi-asserted-by":"crossref","DOI":"10.1007\/s40495-020-00216-7","article-title":"An update on current therapeutic drugs treating COVID-19","author":"Wu","year":"2020","journal-title":"Curr. Pharmacol. Rep."},{"key":"10.1016\/j.sjbs.2021.01.051_b0270","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ejphar.2019.03.021","article-title":"Tanshinone I inhibits vascular smooth muscle cell proliferation by targeting insulin-like growth factor-1 receptor\/phosphatidylinositol-3-kinase signaling pathway","volume":"853","author":"Wu","year":"2019","journal-title":"Eur. J. Pharmacol."},{"issue":"10251","key":"10.1016\/j.sjbs.2021.01.051_b0275","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0140-6736(20)31757-8","article-title":"Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study","volume":"396","author":"Young","year":"2020","journal-title":"The Lancet"},{"issue":"12","key":"10.1016\/j.sjbs.2021.01.051_b0280","doi-asserted-by":"crossref","first-page":"4049","DOI":"10.1016\/j.bmcl.2012.04.081","article-title":"Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13","volume":"22","author":"Yu","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.sjbs.2021.01.051_b0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.108599","article-title":"Tanshinone IIA protects against heart failure post-myocardial infarction via AMPKs\/mTOR-dependent autophagy pathway","volume":"112","author":"Zhang","year":"2019","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.sjbs.2021.01.051_b0290","doi-asserted-by":"crossref","DOI":"10.1038\/s41392-020-00343-z","article-title":"A cell-based large-scale screening of natural compounds for inhibitors of SARS-CoV-2","author":"Zhang","year":"2020","journal-title":"Signal Transduct. Targeted Therapy"}],"container-title":["Saudi Journal of Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21000528?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21000528?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:11:32Z","timestamp":1761153092000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1319562X21000528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S1319562X21000528"],"URL":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.01.051","relation":{},"ISSN":["1319-562X"],"issn-type":[{"value":"1319-562X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Computational drug screening against the SARS-CoV-2 Saudi Arabia isolates through a multiple-sequence alignment approach","name":"articletitle","label":"Article Title"},{"value":"Saudi Journal of Biological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.01.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}