{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:22:14Z","timestamp":1790191334270,"version":"4.1.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T00:00:00Z","timestamp":1625443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004902","name":"Akademie der Naturwissenschaften","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004902","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008485","name":"Schweizerische Akademie der Medizinischen Wissenschaften","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008485","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016208","name":"University of Chittagong","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016208","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Saudi Journal of Biological Sciences"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.sjbs.2021.07.016","type":"journal-article","created":{"date-parts":[[2021,7,10]],"date-time":"2021-07-10T00:51:08Z","timestamp":1625878268000},"page":"6375-6383","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"title":["Deciphering the CNS anti-depressant, antioxidant and cytotoxic profiling of methanol and aqueous extracts of Trametes versicolor and molecular interactions of its phenolic compounds"],"prefix":"10.1016","volume":"28","author":[{"given":"S.M.","family":"Moazzem Hossen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Akramul Hoque Tanim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Shahadat Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad","family":"Ahmed Sami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazim","family":"Uddin Emon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sjbs.2021.07.016_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.jsps.2020.11.004","article-title":"Pharmacological and computer-aided studies provide new insights into Millettia peguensis Ali (Fabaceae)","author":"Alam","year":"2020","journal-title":"Saudi Pharm. J."},{"issue":"4","key":"10.1016\/j.sjbs.2021.07.016_b0010","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00406-004-0484-3","article-title":"Antioxidant enzyme and malondialdehyde values in social phobia before and after citalopram treatment","volume":"254","author":"Atmaca","year":"2004","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.sjbs.2021.07.016_b0015","doi-asserted-by":"crossref","unstructured":"Beck, A.T., Alford, B.A., 2009. Depression: Causes and treatment, University of Pennsylvania Press.","DOI":"10.9783\/9780812290882"},{"issue":"6","key":"10.1016\/j.sjbs.2021.07.016_b0020","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1107\/S0907444902003451","article-title":"The protein data bank","volume":"58","author":"Berman","year":"2002","journal-title":"Acta Crystall. Section D: Biol. Crystall."},{"issue":"2","key":"10.1016\/j.sjbs.2021.07.016_b0025","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/nrn1846","article-title":"New approaches to antidepressant drug discovery: beyond monoamines","volume":"7","author":"Berton","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"issue":"6","key":"10.1016\/j.sjbs.2021.07.016_b0030","first-page":"565","article-title":"Experimental methods for evaluation of psychotropic agents in rodents: I-Anti-anxiety agents","volume":"35","author":"Bhattacharya","year":"1997","journal-title":"Indian J. Exp. Biol."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0035","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.beproc.2008.02.019","article-title":"The exploratory behaviour of rats in the hole-board apparatus: is head-dipping a valid measure of neophilia?","volume":"78","author":"Brown","year":"2008","journal-title":"Behav. Process."},{"issue":"6652","key":"10.1016\/j.sjbs.2021.07.016_b0040","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/39645","article-title":"Molecular basis of agonism and antagonism in the oestrogen receptor","volume":"389","author":"Brzozowski","year":"1997","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.sjbs.2021.07.016_b0045","first-page":"424","article-title":"Compounds from wild mushrooms with antitumor potential","volume":"10","author":"Cfr Ferreira","year":"2010","journal-title":"Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer Agents)"},{"issue":"7599","key":"10.1016\/j.sjbs.2021.07.016_b0050","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/nature17629","article-title":"X-ray structures and mechanism of the human serotonin transporter","volume":"532","author":"Coleman","year":"2016","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0055","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/S0022-3565(24)39013-5","article-title":"Antidepressant-like behavioral effects mediated by 5-hydroxytryptamine2C receptors","volume":"295","author":"Cryan","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0060","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/jps.3030460119","article-title":"The pharmacological activity of a series of basic esters of mono-and dialkylmalonic acids","volume":"46","author":"Dunham","year":"1957","journal-title":"J. Am. Pharm. Assoc."},{"issue":"9877","key":"10.1016\/j.sjbs.2021.07.016_b0065","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/S0140-6736(13)60970-8","article-title":"Reconsidering the declaration of Helsinki","volume":"381","author":"Emanuel","year":"2013","journal-title":"The Lancet"},{"key":"10.1016\/j.sjbs.2021.07.016_b0070","first-page":"1","article-title":"Evaluation of pharmacological potentials of the aerial part of Achyranthes aspera L.: in vivo, in vitro and in silico approaches","author":"Emon","year":"2020","journal-title":"Adv. Traditional Med."},{"issue":"2","key":"10.1016\/j.sjbs.2021.07.016_b0075","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/fsn3.2047","article-title":"Antidepressant, anxiolytic, antipyretic, and thrombolytic profiling of methanol extract of the aerial part of Piper nigrum: In vivo, in vitro, and in silico approaches","volume":"9","author":"Emon","year":"2021","journal-title":"Food Sci. Nutrit."},{"key":"10.1016\/j.sjbs.2021.07.016_b0080","first-page":"1","article-title":"Investigation of antinociceptive, anti-inflammatory and thrombolytic activity of Caesalpinia digyna (Rottl.) leaves by experimental and computational approaches","author":"Emon","year":"2020","journal-title":"Adv. Tradit. Med."},{"issue":"6A","key":"10.1016\/j.sjbs.2021.07.016_b0085","first-page":"3903","article-title":"Strong antioxidant activity of ellagic acid in mammalian cells in vitro revealed by the comet assay","volume":"21","author":"Festa","year":"2001","journal-title":"Anticancer Res."},{"issue":"5","key":"10.1016\/j.sjbs.2021.07.016_b0090","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/0091-3057(85)90064-4","article-title":"The effects of PK 11195, a ligand for benzodiazepine binding sites, in animal tests of anxiety and stress","volume":"23","author":"File","year":"1985","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"7","key":"10.1016\/j.sjbs.2021.07.016_b0095","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1021\/jm0306430","article-title":"Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy","volume":"47","author":"Friesner","year":"2004","journal-title":"J. Med. Chem."},{"issue":"21","key":"10.1016\/j.sjbs.2021.07.016_b0100","doi-asserted-by":"crossref","first-page":"6177","DOI":"10.1021\/jm051256o","article-title":"Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein\u2212 ligand complexes","volume":"49","author":"Friesner","year":"2006","journal-title":"J. Med. Chem."},{"issue":"4","key":"10.1016\/j.sjbs.2021.07.016_b0105","doi-asserted-by":"crossref","first-page":"265","DOI":"10.4103\/0974-8490.118825","article-title":"Anticonvulsant potential of ethanol extracts and their solvent partitioned fractions from Flemingia strobilifera root","volume":"5","author":"Gahlot","year":"2013","journal-title":"Pharmacognosy Res."},{"issue":"5","key":"10.1016\/j.sjbs.2021.07.016_b0110","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines8050135","article-title":"Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: targets and efficacy","volume":"8","author":"Habtemariam","year":"2020","journal-title":"Biomedicines"},{"issue":"5","key":"10.1016\/j.sjbs.2021.07.016_b0115","article-title":"Sedative and anxiolytic effects of different fractions of the Commelina benghalensis Linn","volume":"3","author":"Hasan","year":"2009","journal-title":"Drug Discoveries & Therapeutics"},{"key":"10.1016\/j.sjbs.2021.07.016_b0120","first-page":"683","article-title":"Antioxidant and antimicrobial activities of methanol extracts of some Verbena species: In vitro evaluation of antioxidant and antimicrobial activity in relation to polyphenolic content","volume":"6","author":"Hela","year":"2010","journal-title":"J. Appl. Sci. Res."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0125","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.jep.2006.10.008","article-title":"Sedative and hypnotic activities of the ethanol fraction from Fructus Schisandrae in mice and rats","volume":"110","author":"Huang","year":"2007","journal-title":"J. Ethnopharmacol."},{"issue":"2","key":"10.1016\/j.sjbs.2021.07.016_b0130","first-page":"85","article-title":"Antioxidant\/anti-inflammatory activities and chemical composition of extracts from the mushroom Trametes versicolor","volume":"2","author":"Kamiyama","year":"2013","journal-title":"Int. J. Nutr. Food Sci."},{"key":"10.1016\/j.sjbs.2021.07.016_b0135","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3389\/fphar.2016.00176","article-title":"Antioxidant, antinociceptive and CNS activities of Viscum orientale and high sensitive quantification of bioactive polyphenols by UPLC","volume":"7","author":"Khatun","year":"2016","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.sjbs.2021.07.016_b0140","first-page":"1","article-title":"An in-silico approach: identification of PPAR-\u03b3 agonists from seaweeds for the management of alzheimer\u2019s disease","author":"Kotha","year":"2020","journal-title":"J. Biomol. Struct. Dyn."},{"key":"10.1016\/j.sjbs.2021.07.016_b0145","series-title":"AVMA guidelines for the euthanasia of animals","author":"Leary","year":"2013"},{"issue":"32","key":"10.1016\/j.sjbs.2021.07.016_b0150","doi-asserted-by":"crossref","first-page":"5365","DOI":"10.1021\/bi500525s","article-title":"Structures of KcsA in complex with symmetrical quaternary ammonium compounds reveal a hydrophobic binding site","volume":"53","author":"Lenaeus","year":"2014","journal-title":"Biochemistry"},{"issue":"4","key":"10.1016\/j.sjbs.2021.07.016_b0155","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s11427-011-4153-2","article-title":"Purification and characterization of a novel immunomodulatory protein from the medicinal mushroom Trametes versicolor","volume":"54","author":"Li","year":"2011","journal-title":"Sci. China Life Sci."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0160","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0165-0327(99)00121-4","article-title":"Lower serum vitamin E concentrations in major depression. Another marker of lowered antioxidant defenses in that illness","volume":"58","author":"Maes","year":"2000","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sjbs.2021.07.016_b0165","first-page":"5","article-title":"Effects of acute and chronic administration of Cannabis satis and (-) 9-trans tetrahydro cannabinaol on the behaviour of rats in open field arena","volume":"2","author":"Mansur","year":"1980","journal-title":"Psychopharmacol"},{"key":"10.1016\/j.sjbs.2021.07.016_b0170","doi-asserted-by":"crossref","unstructured":"Meyer, B.N., Ferrigni, N.R., Putnam, J.E., Jacobsen, L.B., Nichols, D.E.j., McLaughlin, J.L., 1982. Brine shrimp: a convenient general bioassay for active plant constituents. Planta Medica 45(05), 31\u201334.","DOI":"10.1055\/s-2007-971236"},{"issue":"1\u20132","key":"10.1016\/j.sjbs.2021.07.016_b0175","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.psychres.2006.04.013","article-title":"Evidence for oxidative stress in the frontal cortex in patients with recurrent depressive disorder\u2014a postmortem study","volume":"151","author":"Michel","year":"2007","journal-title":"Psychiatry Res."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ptr.5222","article-title":"Alhagi: a plant genus rich in bioactives for pharmaceuticals","volume":"29","author":"Muhammad","year":"2015","journal-title":"Phytotherapy Res."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0185","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1517\/14728214.2015.1049996","article-title":"Emerging drugs for the treatment of anxiety","volume":"20","author":"Murrough","year":"2015","journal-title":"Expert Opin. Emerging Drugs"},{"issue":"31","key":"10.1016\/j.sjbs.2021.07.016_b0190","doi-asserted-by":"crossref","first-page":"29","DOI":"10.5530\/pj.2012.31.6","article-title":"Antioxidant, analgesic and CNS depressant effects of Synedrella nodiflora","volume":"4","author":"Nahar","year":"2012","journal-title":"Pharmacognosy Journal"},{"issue":"20","key":"10.1016\/j.sjbs.2021.07.016_b0195","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1001\/jama.2013.281316","article-title":"The Declaration of Helsinki, 50 years later","volume":"310","author":"Ndebele","year":"2013","journal-title":"JAMA"},{"issue":"6","key":"10.1016\/j.sjbs.2021.07.016_b0200","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1017\/S1461145707008401","article-title":"Oxidative stress in psychiatric disorders: evidence base and therapeutic implications","volume":"11","author":"Ng","year":"2008","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.sjbs.2021.07.016_b0205","first-page":"458","article-title":"Biological screening of Kenya medicinal plants using Artemia salina (Artemiidae)","volume":"2","author":"Nguta","year":"2011","journal-title":"Pharmacologyonline"},{"key":"10.1016\/j.sjbs.2021.07.016_b0210","unstructured":"Nyeem, A.B., Alam, M.A., Awal, M.A., Mostafa, M., Uddin, S.J., Islam, N. Rouf, R., 2006. CNS depressant effect of the crude ethanolic extract of the flowering tops of Rosa damascena."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0215","first-page":"195","article-title":"Papaver Rhoeas L. hydroalcoholic extract exacerbates forced swimming test-induced depression in mice","volume":"7","author":"Osanloo","year":"2016","journal-title":"Basic Clin. Neurosci."},{"key":"10.1016\/j.sjbs.2021.07.016_b0220","doi-asserted-by":"crossref","unstructured":"\u00d6Zg\u00d6R, E., M. Ulusoy, \u0130. \u00c7Eleb\u0130Er, S. Yildiz and N. Kesk\u0130N (2016). \u201cInvestigation of antimicrobial activity of different Trametes versicolor extracts on some clinical isolates.\u201d Biological Chemistry 43: 267-272.","DOI":"10.15671\/HJBC.20164420569"},{"issue":"2","key":"10.1016\/j.sjbs.2021.07.016_b0225","doi-asserted-by":"crossref","first-page":"343","DOI":"10.15835\/nbha46211132","article-title":"Characterization of Trametes versicolor: Medicinal mushroom with important health benefits","volume":"46","author":"Puia","year":"2018","journal-title":"Notulae Botanicae Horti Agrobotanici Cluj-Napoca"},{"key":"10.1016\/j.sjbs.2021.07.016_b0230","first-page":"45","article-title":"Phytopharmacological evaluation of leaves of olive-Olea europaea","volume":"1","author":"Rahman","year":"2015","journal-title":"Pharmacologyonline"},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0235","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S0367-326X(00)00243-4","article-title":"Sedative properties of the decoction of the rhizome of Cyperus articulatus","volume":"72","author":"Rakotonirina","year":"2001","journal-title":"Fitoterapia"},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0240","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s43440-020-00163-6","article-title":"Molecular insights into the therapeutic promise of targeting HMGB1 in depression","volume":"73","author":"Rana","year":"2021","journal-title":"Pharmacol Rep"},{"issue":"Pt 3","key":"10.1016\/j.sjbs.2021.07.016_b0245","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1107\/S0907444903029718","article-title":"Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode","volume":"60","author":"Retailleau","year":"2004","journal-title":"Acta Crystallogr D Biol Crystallogr"},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0250","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1021\/acs.jctc.8b01026","article-title":"OPLS3e: Extending force field coverage for drug-like small molecules","volume":"15","author":"Roos","year":"2019","journal-title":"J. Chem. Theory Comput."},{"issue":"21","key":"10.1016\/j.sjbs.2021.07.016_b0255","doi-asserted-by":"crossref","first-page":"4994","DOI":"10.3390\/molecules25214994","article-title":"Evaluation of various solvent extracts of Tetrastigma leucostaphylum (Dennst.) Alston leaves, a Bangladeshi traditional medicine used for the treatment of Diarrhea","volume":"25","author":"Rudra","year":"2020","journal-title":"Molecules"},{"issue":"4","key":"10.1016\/j.sjbs.2021.07.016_b0260","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1254\/jphs.FP0060837","article-title":"Changes in emotional behavior of mice in the hole-board test after olfactory bulbectomy","volume":"102","author":"Saitoh","year":"2006","journal-title":"J. Pharmacol. Sci."},{"issue":"7","key":"10.1016\/j.sjbs.2021.07.016_b0265","first-page":"795","article-title":"Antidepressant-like effect of aqueous extract of Channa striatus fillet in mice models of depression","volume":"15","author":"Saleem","year":"2011","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"8","key":"10.1016\/j.sjbs.2021.07.016_b0270","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1177\/0269881107077609","article-title":"Coronary artery disease risk factors in patients with schizophrenia: effects of short term antipsychotic treatment","volume":"21","author":"Sarandol","year":"2007","journal-title":"J Psychopharmacol"},{"issue":"145","key":"10.1016\/j.sjbs.2021.07.016_b0275","first-page":"165","article-title":"Anti-diabetic effect of methanol extract of Trametes versicolor on male mice","volume":"26","author":"Shokrzadeh","year":"2017","journal-title":"J. Mazandaran Univ. Med. Sci."},{"issue":"7","key":"10.1016\/j.sjbs.2021.07.016_b0280","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1002\/pds.1541","article-title":"A comparison of antidepressant use in Nova Scotia, Canada and Australia","volume":"17","author":"Smith","year":"2008","journal-title":"Pharmacoepidemiol. Drug Saf."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0285","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.pbb.2004.01.019","article-title":"Antianxiety and antidepressant effects of riparin III from Aniba riparia (Nees) Mez (Lauraceae) in mice","volume":"78","author":"Sousa","year":"2004","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.sjbs.2021.07.016_b0290","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1146\/annurev.clinpsy.1.102803.143948","article-title":"The psychobiology of depression and resilience to stress: implications for prevention and treatment","volume":"1","author":"Southwick","year":"2005","journal-title":"Annu. Rev. Clin. Psychol."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0295","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0024-3205(93)90220-W","article-title":"A possible mechanism of antidepresant activity of beta-amyrin palmitate isolated from Lobelia inflata leaves in the forced swimming test","volume":"52","author":"Subarnas","year":"1993","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0300","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40816-018-0063-1","article-title":"Evaluation of central nervous system (CNS) depressant activity of methanolic extract of Commelina diffusa Burm. in mice","volume":"4","author":"Sultana","year":"2018","journal-title":"Clin. Phytosci."},{"issue":"6","key":"10.1016\/j.sjbs.2021.07.016_b0305","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/S0021-5198(19)36179-7","article-title":"Studies of the spontaneous movement of animals by the hole cross test; effect of 2-dimethyl-aminoethanol and its acyl esters on the central nervous system","volume":"21","author":"Takagi","year":"1971","journal-title":"Japanese J. Pharmacol."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0310","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0014-2999(98)00223-4","article-title":"Changes in head-dipping behavior in the hole-board test reflect the anxiogenic and\/or anxiolytic state in mice","volume":"350","author":"Takeda","year":"1998","journal-title":"Eur. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.sjbs.2021.07.016_b0315","doi-asserted-by":"crossref","first-page":"409","DOI":"10.4103\/0253-7613.161265","article-title":"Evaluation of skeletal muscle relaxant activity of aqueous extract of Nerium oleander flowers in Albino rats","volume":"47","author":"Tirumalasetti","year":"2015","journal-title":"Indian J. Pharmacol."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0320","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jad.2005.12.010","article-title":"Possible connections among job stress, depressive symptoms, lipid modulation and antioxidants","volume":"91","author":"Tsuboi","year":"2006","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0325","doi-asserted-by":"crossref","first-page":"1300990","DOI":"10.1080\/23312025.2017.1300990","article-title":"Estimation of in vivo neuropharmacological and in vitro antioxidant effects of Tetracera sarmentosa","volume":"3","author":"Uddin Mazumdar","year":"2017","journal-title":"Cogent Biology"},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0330","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2174\/157015909787602823","article-title":"Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options","volume":"7","author":"Uttara","year":"2009","journal-title":"Curr. Neuropharmacol."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.016_b0335","first-page":"21","article-title":"Phytochemical and pharmacological potential of Nerium oleander: a review","volume":"1","author":"Vikas","year":"2010","journal-title":"Int. J. Pharm. Sci. Res. (IJPSR)"},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.016_b0340","doi-asserted-by":"crossref","first-page":"1261577","DOI":"10.1080\/23312025.2016.1261577","article-title":"Catechins from green tea modulate neurotransmitter transporter activity in Xenopus oocytes","volume":"2","author":"Wang","year":"2016","journal-title":"Cogent Biol."},{"issue":"7","key":"10.1016\/j.sjbs.2021.07.016_b0345","doi-asserted-by":"crossref","first-page":"801","DOI":"10.3109\/13880200903280042","article-title":"Anxiolytic and sedative-hypnotic activities of polygalasaponins from Polygala tenuifolia in mice","volume":"48","author":"Yao","year":"2010","journal-title":"Pharm. Biol."},{"issue":"4","key":"10.1016\/j.sjbs.2021.07.016_b0350","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyu077","article-title":"Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation","volume":"18","author":"Zhang","year":"2015","journal-title":"Int. J. Neuropsychopharmacol."},{"issue":"4","key":"10.1016\/j.sjbs.2021.07.016_b0355","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.cell.2008.01.033","article-title":"Mechanisms and functional implications of adult neurogenesis","volume":"132","author":"Zhao","year":"2008","journal-title":"Cell"}],"container-title":["Saudi Journal of Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21005891?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21005891?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:17:35Z","timestamp":1761153455000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1319562X21005891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":71,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S1319562X21005891"],"URL":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.07.016","relation":{},"ISSN":["1319-562X"],"issn-type":[{"value":"1319-562X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Deciphering the CNS anti-depressant, antioxidant and cytotoxic profiling of methanol and aqueous extracts of Trametes versicolor and molecular interactions of its phenolic compounds","name":"articletitle","label":"Article Title"},{"value":"Saudi Journal of Biological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.07.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}