{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:53:25Z","timestamp":1787068405123,"version":"build-2736575974"},"reference-count":32,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,28]],"date-time":"2021-07-28T00:00:00Z","timestamp":1627430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Saudi Journal of Biological Sciences"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.sjbs.2021.07.085","type":"journal-article","created":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T12:52:08Z","timestamp":1627649528000},"page":"6987-6991","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Analysis of CCND1 protein and circulatory antioxidant enzyme activity association in oral squamous cell carcinoma"],"prefix":"10.1016","volume":"28","author":[{"given":"P.S.","family":"Sushma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaiser","family":"Jamil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Udaykumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad M.","family":"Aldakheel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shatha A.","family":"Alduraywish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bader Homoud","family":"Alali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayesha","family":"Mateen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabbani","family":"Syed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sjbs.2021.07.085_b0005","doi-asserted-by":"crossref","unstructured":"Ahmedin, J., Freddie, B. and Melissa, M., 2014. Global cancer statistics. Cancer. J. Clin. 61(2), 69\u201390.","DOI":"10.3322\/caac.20107"},{"key":"10.1016\/j.sjbs.2021.07.085_b0010","doi-asserted-by":"crossref","unstructured":"Aldakheel, F.M., Abuderman, A.A., Alali, B.H., Mateen, A., Alduraywish, S.A., Alqahtani, M.S., Syed, R., 2021. Smoking and P53 polymorphism association with chromosomal aberration in lung cancer. J. King Saud Univ. Sci. p.101533.","DOI":"10.1016\/j.jksus.2021.101533"},{"issue":"7","key":"10.1016\/j.sjbs.2021.07.085_b0015","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1093\/annonc\/mdr562","article-title":"Body mass, tobacco smoking, alcohol drinking and risk of cancer of small intestine \u2013 a pooled analysis of over 500,000 subjects in asia cohort","volume":"23","author":"Boffetta","year":"2011","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.sjbs.2021.07.085_b0030","doi-asserted-by":"crossref","unstructured":"Duan, Y.Z., Zhang, L., Liu, CC., et al., 2013. CCND1 G870A polymorphism interaction with cigarette smoking increases lung cancer risk: meta-analyses based on 5008 cases and 5214 controls. Mol. Biol. Rep. 40, 4625\u20134635.","DOI":"10.1007\/s11033-013-2556-9"},{"issue":"2","key":"10.1016\/j.sjbs.2021.07.085_b0035","first-page":"110","article-title":"Biochemistry of free radicals and antioxidants","volume":"2","author":"Eboh","year":"2014","journal-title":"Scholars. Acad. J. Biosci."},{"key":"10.1016\/j.sjbs.2021.07.085_b0040","doi-asserted-by":"crossref","unstructured":"Ellman, G.L.,1959. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82, 70\u201377.","DOI":"10.1016\/0003-9861(59)90090-6"},{"key":"10.1016\/j.sjbs.2021.07.085_b0045","doi-asserted-by":"crossref","unstructured":"Farhad,I., Irene, T. and Mathorota, 2010. Alcoholic drinking and laryngeal cancers overall and dose- risk relation- A systematic review and meta analysis. Oral. Oncol. 46(11), 802\u2013810.","DOI":"10.1016\/j.oraloncology.2010.07.015"},{"key":"10.1016\/j.sjbs.2021.07.085_b0050","doi-asserted-by":"crossref","unstructured":"Hemmer, S., Wasenius, V.M., Haglund, C., Zhu, Y., Knuutila, S., Franssila, K., Joensuu H., 2001. Deletion of 11q23 and cyclin D1 overexpression are frequent aberrations in parathyroid adenomas. Am. J. Pathol. 158, 1355\u20131362.","DOI":"10.1016\/S0002-9440(10)64086-2"},{"issue":"6","key":"10.1016\/j.sjbs.2021.07.085_b0055","first-page":"725","article-title":"Areca nut extract induced oxidative stress and upregulated hypoxia induced factor leading to autophagy in oral cancer cells","volume":"6","author":"Hsuan","year":"2010","journal-title":"Atg."},{"key":"10.1016\/j.sjbs.2021.07.085_b0060","series-title":"Toxicology and disease\/ cancer therapy in reactive oxygen species-Mediated drugs and treatment","first-page":"860563","author":"Hsuch","year":"2014"},{"issue":"22","key":"10.1016\/j.sjbs.2021.07.085_b0065","doi-asserted-by":"crossref","first-page":"9579","DOI":"10.7314\/APJCP.2014.15.22.9579","article-title":"Overweight, Obesity oxidative stress & risk on breast cancer","volume":"15","author":"Joanna","year":"2014","journal-title":"Asian. Pac. J. Cancer. Prev."},{"key":"10.1016\/j.sjbs.2021.07.085_b0070","doi-asserted-by":"crossref","unstructured":"Kandel, R., Zhu, X.L., Li, S.Q and Rohan, T., 2001.Cyclin D1 protein overexpression and gene amplification in benign breast tissue and breast cancer risk. Eur. J. Cancer. Prev. 10, 43\u201351.","DOI":"10.1097\/00008469-200102000-00005"},{"key":"10.1016\/j.sjbs.2021.07.085_b0075","doi-asserted-by":"crossref","unstructured":"Lawrence, R.A., Sunde, R.A., Schwartz, G.L., et al., 1974. Glutathione peroxidase activity in rat lens and other tissues in relation to dietary selenium intake. Exp. Eye Res.18, 563\u2013569.","DOI":"10.1016\/0014-4835(74)90062-1"},{"issue":"12","key":"10.1016\/j.sjbs.2021.07.085_b0080","article-title":"Cyclin D1 depletion interferes with oxidative balance and promotes cancer cell senescence","volume":"131","author":"Laphanuwat","year":"2018","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.sjbs.2021.07.085_b0085","doi-asserted-by":"crossref","unstructured":"Luca, C.D., Kharaeya, Z., Korkina., 2015. Is there a role of antioxidants in the prevention of infection associated carcinogenesis and in the treatment of infection driven tumors. Curr. Top. Med. Chem. 15(2), 120\u2013135.","DOI":"10.2174\/1568026615666141209145022"},{"key":"10.1016\/j.sjbs.2021.07.085_b0090","doi-asserted-by":"crossref","unstructured":"Marklund, S., Marklund, G., 1974. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47, 469\u2013474.","DOI":"10.1111\/j.1432-1033.1974.tb03714.x"},{"issue":"5","key":"10.1016\/j.sjbs.2021.07.085_b0095","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1038\/bjc.2012.333","article-title":"Alcohol drinking, tobacco smoking and subtypes of haematological malignancy in UK million women study","volume":"107","author":"Kroll","year":"2012","journal-title":"British J. Cancer."},{"issue":"3","key":"10.1016\/j.sjbs.2021.07.085_b0100","first-page":"390","article-title":"Evaluation of two novel antioxidants with differential effects on curcumin induced apoptosis in C2 skeletal myoblasts: involvement of JNKs","volume":"23","author":"Maria","year":"2014","journal-title":"Bioorg. Med. Chem."},{"issue":"2","key":"10.1016\/j.sjbs.2021.07.085_b0105","doi-asserted-by":"crossref","first-page":"170","DOI":"10.2174\/1568026615666141209160918","article-title":"Antioxidant supplementation on cancer risk and concurrent use of antioxidants during cancer therapy: an update","volume":"15","author":"Ozben","year":"2015","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.sjbs.2021.07.085_b0110","doi-asserted-by":"crossref","unstructured":"Perni, Stefano., Calzuda., 2014. Natural antioxidants in wheat sprout extracts. Curr. Org. Chem. 18 (23), 2950\u20132960.","DOI":"10.2174\/1385272819666140923221446"},{"key":"10.1016\/j.sjbs.2021.07.085_b0115","doi-asserted-by":"crossref","unstructured":"Stefanopetti, 2009. Lifestyle risk factors for oral cancers. Oral. Oncol. 45(4-5) (2009), 340\u201350.","DOI":"10.1016\/j.oraloncology.2008.05.018"},{"key":"10.1016\/j.sjbs.2021.07.085_b0120","doi-asserted-by":"crossref","unstructured":"Sinha, A.K., Colorimetric assay of catalase. Anal. Biochem. 47, (1972) 389\u2013394.","DOI":"10.1016\/0003-2697(72)90132-7"},{"key":"10.1016\/j.sjbs.2021.07.085_b0125","doi-asserted-by":"crossref","unstructured":"Surinder, K., David, B.l., 2015. Mitochondrial Sirtuins & their relationship with metabolic diseases and cancer. Antioxid. Redox. Signal. 22(12), 1060\u20131077.","DOI":"10.1089\/ars.2014.6213"},{"issue":"2","key":"10.1016\/j.sjbs.2021.07.085_b0130","first-page":"3","article-title":"Bioantioxidant activity: Their mechanism and measurement methods","volume":"1","author":"Sahari","year":"2014","journal-title":"Appl. Food. Biotechno."},{"key":"10.1016\/j.sjbs.2021.07.085_b0135","doi-asserted-by":"crossref","unstructured":"Saawarn, S., Astekar, M., Saawarn, N., Dhakar, N., Gomateshwar, S.S., 2012. Cyclin d1 expression and its correlation with histopathological differentiation in oral squamous cell carcinoma. Sci. World. J. Article No.978327.","DOI":"10.1100\/2012\/978327"},{"key":"10.1016\/j.sjbs.2021.07.085_b0140","doi-asserted-by":"crossref","unstructured":"Santarius, T., Shipley, J., Brewer, D., Stratton, M.R., Cooper, C.S., 2010. A census of amplified and overexpressed human cancer genes. Nat. Rev. Cancer. 10, 59\u201364.","DOI":"10.1038\/nrc2771"},{"key":"10.1016\/j.sjbs.2021.07.085_b0145","doi-asserted-by":"crossref","unstructured":"Sgambato, A., Migaldi, M., Faraglia, B., et al., 2002. Cyclin D1 expression in papillary superficial bladder cancer: its association with other cell cycle-associated proteins, cell proliferation and clinical outcome. Int. J. Cancer. 97,671\u2013678.","DOI":"10.1002\/ijc.10055"},{"key":"10.1016\/j.sjbs.2021.07.085_b0150","first-page":"3683","article-title":"Targeting cyclin D1 in non-small cell lung cancer and mesothelioma cells by antisense oligonucleotides","volume":"31","author":"Saini","year":"2011","journal-title":"Anticancer. Res."},{"key":"10.1016\/j.sjbs.2021.07.085_b0155","doi-asserted-by":"crossref","unstructured":"Tramacera, Negri, E., Pelucchi,C., 2012. A metaanalysis on alcoholic drinking & gastric cancer. Ann. Oncol. 23(1), 28\u201336.","DOI":"10.1093\/annonc\/mdr135"},{"key":"10.1016\/j.sjbs.2021.07.085_b0160","first-page":"975","article-title":"Overexpression of cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck","volume":"55","author":"Michalides","year":"1995","journal-title":"Cancer. Res."},{"issue":"1","key":"10.1016\/j.sjbs.2021.07.085_b0165","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s13046-014-0106-5","article-title":"Dual effect of oxidative stress on leukemia cancer induction and treatment","volume":"33","author":"Udensi","year":"2014","journal-title":"J. Exp. Clin. Cancer. Res."},{"key":"10.1016\/j.sjbs.2021.07.085_b0170","doi-asserted-by":"crossref","unstructured":"Weinstein, I.B., Joe, A.K., 2006. Mechanisms of disease: oncogene addiction\u2013a rationale for molecular targeting in cancer therapy. Nat. Clin. Pract. Oncol. 3, 448\u2013457.","DOI":"10.1038\/ncponc0558"}],"container-title":["Saudi Journal of Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21006689?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21006689?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:12:45Z","timestamp":1761153165000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1319562X21006689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":32,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S1319562X21006689"],"URL":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.07.085","relation":{},"ISSN":["1319-562X"],"issn-type":[{"value":"1319-562X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Analysis of CCND1 protein and circulatory antioxidant enzyme activity association in oral squamous cell carcinoma","name":"articletitle","label":"Article Title"},{"value":"Saudi Journal of Biological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.07.085","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}