{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:20:48Z","timestamp":1792844448182,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Saudi Journal of Biological Sciences"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.sjbs.2021.09.060","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T18:24:21Z","timestamp":1633112661000},"page":"7575-7580","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Potential benefits of gallic acid as skeletal muscle relaxant in animal experimental models"],"prefix":"10.1016","volume":"28","author":[{"given":"Syed Mohammed Basheeruddin","family":"Asdaq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulhakeem S.","family":"Alamri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walaa F.","family":"Alsanie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Majid","family":"Alhomrani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhana","family":"Yasmin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.sjbs.2021.09.060_b0005","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.jep.2005.11.035","article-title":"Neurosedative and muscle-relaxant activities of ethyl acetate extract of Baphia nitida AFZEL","volume":"106","author":"Adeyemi","year":"2006","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.sjbs.2021.09.060_b0010","unstructured":"Ahmad, S.S., Priyambada, S., Vijayalakshmi, P., 2019. Comparative Study of Muscle Relaxant Activity of Midazolam with Diazepam in Male Albino Mice. Int. J. Pharm. Sci. Rev. Res. 58(2), 39\u201344, September - October 2019; Article No. 07. https:\/\/1library.net\/document\/zk34ng4y-comparative-relaxant-activity-midazolam-diazepam-supriya-priyambada-vijayalakshmi.html."},{"key":"10.1016\/j.sjbs.2021.09.060_b0015","doi-asserted-by":"crossref","unstructured":"Ana, C.A., Caroline, B.C., Fernanda, P.G., Fernanda, S.L., Haroldo, C.O., Julhiany, F.S., 2014. Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi .Evidence-Based Complementary and Alternative Medicine. Article ID 506273, 8 pages.","DOI":"10.1155\/2014\/506273"},{"issue":"22","key":"10.1016\/j.sjbs.2021.09.060_b0020","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.3390\/molecules25225287","article-title":"Role of Daucus carota in Enhancing Antiulcer Profile of Pantoprazole in Experimental Animals","volume":"25","author":"Asdaq","year":"2020","journal-title":"Molecules"},{"issue":"11","key":"10.1016\/j.sjbs.2021.09.060_b0025","first-page":"1473","article-title":"Gastrointestinal motility, muscle relaxation, antipyretic and acute toxicity screening of amyrin type triterpenoid (daturaolone) isolated from Datura metel Linnaeus (Angel\u2019s trumpet) fruits","volume":"25","author":"Bawazeer","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"4","key":"10.1016\/j.sjbs.2021.09.060_b0030","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1089\/mdr.2012.0244","article-title":"Sim\u00f5es M Antibacterial activity and mode of action of ferulic and gallic acids against pathogenic bacteria","volume":"19","author":"Borges","year":"2013","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.sjbs.2021.09.060_b0035","unstructured":"Chen, J.J., 2003. Neuroprotection in Parkinson\u2019s disease. Medscape 2004; 5 (Conference report- American College of Clinical Pharmacy Annul Meeting; Nov 2-5, Atlanta, Georgia)."},{"issue":"7","key":"10.1016\/j.sjbs.2021.09.060_b0040","doi-asserted-by":"crossref","first-page":"478","DOI":"10.7326\/0003-4819-147-7-200710020-00006","article-title":"Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society","volume":"147","author":"Chou","year":"2007","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.sjbs.2021.09.060_b0045","unstructured":"Craig, C.R., Stitzel, R.E., 2003. Modern Pharmacology with clinical applications. Lippincott Williams & Wilkins, p. 339. ISBN 0-7817-3762-1."},{"key":"10.1016\/j.sjbs.2021.09.060_b0050","doi-asserted-by":"crossref","unstructured":"Deacon, R.M., 2013. Measuring the strength of mice. J. Visualized Exp. JoVE (76).","DOI":"10.3791\/2610-v"},{"issue":"3","key":"10.1016\/j.sjbs.2021.09.060_b0055","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1007\/s11064-011-0635-7","article-title":"Antianxiety-like activity of gallic acid in unstressed and stressed mice: possible involvement of nitriergic system","volume":"37","author":"Dhingra","year":"2012","journal-title":"Neurochem Res."},{"issue":"2","key":"10.1016\/j.sjbs.2021.09.060_b0060","first-page":"A71","article-title":"Antioxidant and free radical scavenging activities of sumac (Rhus coriaria) and identification of gallic acid as its active principle","volume":"7","author":"Franziska","year":"2007","journal-title":"BMC Pharmacol."},{"key":"10.1016\/j.sjbs.2021.09.060_b0065","doi-asserted-by":"crossref","unstructured":"Garc\u00eda-Campos, Paz, B\u00e1ez-Matus, Ximena, Jara-Guti\u00e9rrez, Carlos, Paz-Araos, Marilyn, Astorga, C\u00e9sar, Cea, Luis A.m Rodr\u00edguez, Viviana, Bevilacqua, Jorge A., Caviedes, Pablo, C\u00e1rdenas, Ana M., 2020. N-Acetylcysteine Reduces Skeletal Muscles Oxidative Stress and Improves Grip Strength in Dysferlin-Deficient Bla\/J Mice. Int. J. Mol. Sci. 21(12), 4293. 10.3390\/ijms21124293.","DOI":"10.3390\/ijms21124293"},{"key":"10.1016\/j.sjbs.2021.09.060_b0070","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1590\/S1984-82502012000300025","article-title":"Antidepressant and skeletal muscle relaxant effects of the aqueous extract of the Prosopis cineraria","volume":"48","author":"George","year":"2012","journal-title":"Braz. J. Pharmaceut. Sci."},{"key":"10.1016\/j.sjbs.2021.09.060_b0075","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/BF02877259","article-title":"Two types of antimutagenic effects of gallic acid and tannic acids towards N nitroso- compounds-induced mutagenecity in the Ames Salmonella assay","volume":"32","author":"Gichner","year":"1987","journal-title":"Folia Microbiol."},{"key":"10.1016\/j.sjbs.2021.09.060_b0080","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0960-894X(01)00811-3","article-title":"New Anti-Malarial Compounds from Database Searching","volume":"12","author":"Griffith","year":"2002","journal-title":"Bioorgan. Med. Chem. Lett."},{"key":"10.1016\/j.sjbs.2021.09.060_b0085","first-page":"168","article-title":"Enhanced Solubility and Bioavailabitity of GA via Preparation of Solid Dispersions of Mesoporous Silica Nanoparticles IRANIAN","volume":"18","author":"Huang","year":"2019","journal-title":"J. Pharm. Res."},{"key":"10.1016\/j.sjbs.2021.09.060_b0090","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1142\/S0192415X98000373","article-title":"Mechanism of the protective effects of sumac gall extract and gallic acid on CCl4-induced acute liver injury in rats","volume":"26","author":"Kanai","year":"1998","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.sjbs.2021.09.060_b0095","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1590\/S0074-02762008000500005","article-title":"Anti-HSV-1 and anti-HIV-1 activity of gallic acid and pentyl gallate","volume":"103","author":"Kratz","year":"2008","journal-title":"Mem. Inst. Oswaldo. Cruz."},{"key":"10.1016\/j.sjbs.2021.09.060_b0100","first-page":"2376","article-title":"Assessment of motor balance and coordination in mice using the balance beam","volume":"49","author":"Luong","year":"2011","journal-title":"J. Vis. Exp."},{"issue":"1","key":"10.1016\/j.sjbs.2021.09.060_b0105","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11418-012-0636-0","article-title":"Evaluation of n-hexane extract of Viola betonicifolia for its neuropharmacological properties","volume":"67","author":"Muhammad","year":"2013","journal-title":"J. Nat. Med."},{"key":"10.1016\/j.sjbs.2021.09.060_b0110","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.18203\/2319-2003.ijbcp20192206","article-title":"A study to evaluate the skeletal muscle relaxant property of Pregabalin and Gabapentin in albino rats","volume":"8","author":"Naidu","year":"2019","journal-title":"Int. J. Basic Clin. Pharmacol."},{"issue":"1","key":"10.1016\/j.sjbs.2021.09.060_b0115","first-page":"43","article-title":"Stability studies and evaluation of the semi solid dosage form of the rutin, quercitin, ellagic acid, gallic acid and sitosterol isolated from the leaves of Tectona grandis for wound healing activity","volume":"3","author":"Nayeem","year":"2011","journal-title":"Archiv. Appl. Sci. Res."},{"key":"10.1016\/j.sjbs.2021.09.060_b0120","doi-asserted-by":"crossref","unstructured":"Nayeem, N., Asdaq, S.M.B., Salem, H., AHEl-Alfqy, S., 2016. Gallic Acid: A Promising Lead Molecule for Drug Development. J. App. Pharm. 8, 213. doi: 10.4172\/1920-4159.1000213","DOI":"10.4172\/1920-4159.1000213"},{"issue":"4","key":"10.1016\/j.sjbs.2021.09.060_b0125","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1017\/S0022149X1300045X","article-title":"Anthelmintic activity of phenolic acids from the axlewood tree Anogeissus leiocarpus on the filarial nematode Onchocerca ochengi and drug-resistant strains of the free-living nematode Caenorhabditis elegans","volume":"88","author":"Ndjonka","year":"2014","journal-title":"Helminthol."},{"issue":"2","key":"10.1016\/j.sjbs.2021.09.060_b0130","doi-asserted-by":"crossref","first-page":"217","DOI":"10.31254\/jsir.2014.3216","article-title":"Evaluation of diuretic activity of gallic acid in normal rats","volume":"3","author":"Ramya","year":"2014","journal-title":"J. Sci. Innov. Res."},{"issue":"4","key":"10.1016\/j.sjbs.2021.09.060_b0135","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1472-8206.2012.01040.x","article-title":"Antidepressant-like activity of gallic acid in mice subjected to unpredictable chronic mild stress","volume":"27","author":"Ritu","year":"2013","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1016\/j.sjbs.2021.09.060_b0140","first-page":"331","article-title":"Comparative antibacterial effect of gallic acid and catechin against Helicobacter pylori","volume":"54","author":"Roberto","year":"2013","journal-title":"Food Sci. Technol."},{"key":"10.1016\/j.sjbs.2021.09.060_b0145","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.indcrop.2012.10.024","article-title":"Hepatoprotective effect of gallic acid isolated from Peltiphyllum peltatum against sodium fluoride-induced oxidative stress","volume":"44","author":"Seyed","year":"2013","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.sjbs.2021.09.060_b0150","doi-asserted-by":"crossref","first-page":"JEN-S25096","DOI":"10.4137\/JEN.S25096","article-title":"Isolation and identification of a flavone GA from marine red alga Acanthophora spicifera with antinociceptive and anti-Inflammatory activities","volume":"10","author":"Shoubaky","year":"2016","journal-title":"J. Exp. Neurosci."},{"issue":"4","key":"10.1016\/j.sjbs.2021.09.060_b0155","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4103\/0974-8490.89743","article-title":"Cardioprotective effects of gallic acid in diabetes-induced myocardial dysfunction in rats","volume":"3","author":"Snehal","year":"2011","journal-title":"Pharmacogn. Res."},{"key":"10.1016\/j.sjbs.2021.09.060_b0160","first-page":"411","article-title":"Antioxidant activity and phenolic content of selected fruit seeds","volume":"88","author":"Soong","year":"2004","journal-title":"Food"},{"issue":"6","key":"10.1016\/j.sjbs.2021.09.060_b0165","article-title":"Assessment of Physician Prescribing of Muscle Relaxants in the United States, 2005\u20132016","volume":"3","author":"Soprano","year":"2020","journal-title":"JAMANetw Open"},{"key":"10.1016\/j.sjbs.2021.09.060_b0170","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1002\/bip.10499","article-title":"Structure\u2013activity relationships in the hydrophobic interactions of polyphenols with cellulose and collagen","volume":"70","author":"Tang","year":"2003","journal-title":"Biopolymers"},{"issue":"1","key":"10.1016\/j.sjbs.2021.09.060_b0175","first-page":"25","article-title":"Inappropriate Use of Skeletal Muscle Relaxants in Geriatric Patients","volume":"45","author":"Trueman","year":"2020","journal-title":"US Pharm."},{"issue":"17","key":"10.1016\/j.sjbs.2021.09.060_b0180","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1097\/01.BRS.0000090503.38830.AD","article-title":"Muscle relaxants for nonspecific low back pain: a systematic review within the framework of the cochrane collaboration","volume":"28","author":"Van Tulder","year":"2003","journal-title":"Spine"},{"issue":"4","key":"10.1016\/j.sjbs.2021.09.060_b0185","first-page":"714","article-title":"Skeletal muscle relaxant property of diazepam by using rotarod on albino mice","volume":"4","author":"Veena","year":"2015","journal-title":"Indian J. Basic Appl. Med. Res."},{"issue":"3","key":"10.1016\/j.sjbs.2021.09.060_b0190","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.febslet.2009.11.092","article-title":"Gallic acid induces GLUT4 translocation and glucose uptake activity in 3T3-L1 cells","volume":"5","author":"Vishnu Prasad","year":"2010","journal-title":"FEBS Lett."},{"key":"10.1016\/j.sjbs.2021.09.060_b0195","unstructured":"Vogel, H.G., Vogel, W.H., 2002. Drug Discovery and Evaluation: Pharmacological Assays, second ed., Springer-Verlag Berlin Heidelberg, New York, 2002, pp. 396\u2013398."},{"key":"10.1016\/j.sjbs.2021.09.060_b0200","first-page":"42","article-title":"Anxiolytic and muscle-relaxant activities of Dalbergia saxatilis","volume":"19","author":"Yemitan","year":"2003","journal-title":"West Afr. J. Pharmacol. Drug Res."}],"container-title":["Saudi Journal of Biological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21008627?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1319562X21008627?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:16:48Z","timestamp":1761153408000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1319562X21008627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":40,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S1319562X21008627"],"URL":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.09.060","relation":{},"ISSN":["1319-562X"],"issn-type":[{"value":"1319-562X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential benefits of gallic acid as skeletal muscle relaxant in animal experimental models","name":"articletitle","label":"Article Title"},{"value":"Saudi Journal of Biological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sjbs.2021.09.060","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.","name":"copyright","label":"Copyright"}]}}