{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:38:36Z","timestamp":1765294716536,"version":"3.46.0"},"reference-count":20,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","scandinavianjournalpain.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2016,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec id=\"j_j.sjpain.2015.07.005_s_001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Complex regional pain syndrome (CRPS) may occur following fractures, surgery or different trauma. Development of CRPS following snake-bite has only been published in three reports (from Turkey, Nepal and Korea), although snake bites occur frequently world-wide. There has been no report from Western Europe. Vipera Berus is a common snake in European countries and the only venomous snake in Norway. We here describe the development of CRPS in a young woman as a consequence of a viper bite (Vipera Berus) in the right arm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_j.sjpain.2015.07.005_s_002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a clinical investigation (inspection, measurement of skin temperatures, sensory and motor evaluation) of the patient six months following the viper-bite, measurement of thermal thresholds (quantitative sensory testing, QST), measurement of resting sweat output (RSO) and quantitative sudomotor axon reflex (QSART) from both arms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_j.sjpain.2015.07.005_s_003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The patient fulfilled the Budapest criteria for a CRPS-condition, with continuous pain and symptoms and findings of autonomic dysfunction. In addition, we found elevated thresholds of warmth and cold, evidence of an affection of afferent A-delta and C-fibres as well as an affection of the efferent sympathetic sudomotor C-fibres by QSART. An increased RSO-volume was in inverse relationship to the decreased QSART result.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"j_j.sjpain.2015.07.005_s_004\">\n                    <jats:title>Conclusion and implications<\/jats:title>\n                    <jats:p>It is important to be aware of viper-bite as a possible eliciting event for CRPS for early diagnosis and treatment of a patient. As long-lasting pain and oedema are known complications, it is probable that CRPS after viper-bites previously may have been underdiagnosed. As many patients are unaware of being bit, viper bite should be considered in cases of unexplained sudden pain and swelling of a limb.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.sjpain.2015.07.005","type":"journal-article","created":{"date-parts":[[2015,8,24]],"date-time":"2015-08-24T07:37:37Z","timestamp":1440401857000},"page":"15-18","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Complex regional pain syndrome following viper-bite"],"prefix":"10.1515","volume":"10","author":[{"given":"Inge Petter","family":"Kleggetveit","sequence":"first","affiliation":[{"name":"Section of Clinical Neurophysiology , Department of Neurology Oslo University Hospital-Rikshospitalet , Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Per Kristian","family":"Skulberg","sequence":"additional","affiliation":[{"name":"Askim Medical Center , Askim , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen","family":"J\u00f8rum","sequence":"additional","affiliation":[{"name":"Section of Clinical Neurophysiology , Department of Neurology Oslo University Hospital-Rikshospitalet , Oslo , Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"374","published-online":{"date-parts":[[2016,1,1]]},"reference":[{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_001","doi-asserted-by":"crossref","unstructured":"de Mos  M, de Bruijn AGJ, Huygen FJPM, Dieleman JP, Stricker BHC, Sturkenboom MCJM. The incidence of complex regional pain syndrome: a population-based study. Pain 2007;129:12\u201320.","DOI":"10.1016\/j.pain.2006.09.008"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_002","doi-asserted-by":"crossref","unstructured":"Sandroni  P, Benrud-Larson LM, McClelland RL, Low PA. Complex regional pain syndrome type I: incidence and prevalence in Olmsted county, a population-based study. Pain 2003;103:199\u2013207. PubMed PMID: 12749974.","DOI":"10.1016\/S0304-3959(03)00065-4"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_003","doi-asserted-by":"crossref","unstructured":"Baron  R, Fields HL, Janig  W, Kitt  C, Levine JD. National institutes of health workshop: reflex sympathetic dystrophy\/complex regional pain syndromes\u2014state-of-the-science. Anesth Analg 2002;95:1812\u20136. PubMed PMID: 12456464.","DOI":"10.1097\/00000539-200212000-00064"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_004","unstructured":"Ergan SA, Yoleri \u00d6, Yavasi  S, \u00d6lmez N, Memi\u00a7 A. Complex regional pain syndrome caused by snake bite: a case report. Turk J Phys Med Rehabil 2012;58:69\u201371."},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_005","unstructured":"Bhattarai  B, Shrestha BP, Rahman TR, Sharma SK, Tripathi M. Complex regional pain syndrome (CRPS) type-1 following snake bite: a case report. Nepal Med Coll J: NMCJ 2008;10:278\u201380. PubMed PMID: 19558072."},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_006","doi-asserted-by":"crossref","unstructured":"Seo YH, Park MR, Yoo SH. Development of complex regional pain syndrome after a snake bite: a case report. Korean J Pain 2014;27:68\u201371. PubMed PMID: 24478904. Pubmed Central PMCID: PMC3903804.","DOI":"10.3344\/kjp.2014.27.1.68"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_007","doi-asserted-by":"crossref","unstructured":"Harden RN, Bruehl  S, Perez RS, Birklein  F, Marinus  J, Maihofner  C, Lubenov  T, Buvanendran  A, Mackey  S, Graciosa  J, Mogilevski  M, Ramsden  C, Chont  M, Vatine JJ. Validation of proposed diagnostic criteria (the \u201cBudapest Criteria\u201d) for complex regional pain syndrome. Pain 2010;150:268\u201374.","DOI":"10.1016\/j.pain.2010.04.030"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_008","unstructured":"Low PA. Laboratory evaluation of autonomic function. In: Low PA, editor. Clinical autonomic disorders: evaluation and management. 2nd ed. Lippincott-Raven Publishers; 1997. 179\u2013208."},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_009","doi-asserted-by":"crossref","unstructured":"Reading CJ. Incidence, pathology, and treatment of adder (Vipera berus L.) bites in man. J Accid Emerg Med 1996;13:346\u201351. PubMed PMID: 8894864. Pubmed Central PMCID: PMC1342773.","DOI":"10.1136\/emj.13.5.346"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_010","unstructured":"Aakvik  R, Refstad  S, Ringstad LG, Jacobsen D. Adderbites inNorway\u2014occurrence and treatment. Tidsskrift for den Norske laegeforening: tidsskrift for praktisk medicin, ny raekke 2004;124:1779\u201381. PubMed PMID: 15229667. Hoggormbitt-forekomst og behandling."},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_011","doi-asserted-by":"crossref","unstructured":"Reid HA. Adder bites in Britain. Br Med J 1976;2:153\u20136. PubMed PMID: 1276841. Pubmed Central PMCID: PMC1687390.","DOI":"10.1136\/bmj.2.6028.153"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_012","unstructured":"Solheim R. Bites by vipers. Tidsskrift for den Norske laegeforening: tidsskrift for praktisk medicin, ny raekke 2003;123:1886\u20138. PubMed PMID: 12830276."},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_013","unstructured":"Helsebiblioteket.no Huggorm - behandlingsanbefaling ved forgiftning 2011. Available from: http:\/\/www.helsebiblioteket.no\/forgiftninger\/stikk-og-bitt\/huggorm-behandlingsanbefaling-ved-forgiftning [accessed on 24.06.11]."},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_014","doi-asserted-by":"crossref","unstructured":"Meyer RA, Ringkamp  M, Campbell JN, Raja SN. Peripheral mechanisms of cutaneous nociception. In: McMahon SB, Koltzenburg  M, editors. Wall and Melzack\u2019s textbook of pain. 5th ed. Elsevier Churchill Livingstone; 2006. p. 3\u201334.","DOI":"10.1016\/B0-443-07287-6\/50006-0"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_015","doi-asserted-by":"crossref","unstructured":"Bohlen CJ, Chesler AT, Sharif-Naeini  R, Medzihradszky KF, Zhou  S, King  D, Sanchez EE, Burlingame AL, Basbaum AI, Julius D. A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature 2011;479:410\u20134. PubMed PMID: 22094702. Pubmed Central PMCID: PMC3226747.","DOI":"10.1038\/nature10607"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_016","doi-asserted-by":"crossref","unstructured":"Diochot  S, Baron  A, Salinas  M, Douguet  D, Scarzello  S, Dabert-Gay AS, Debayle  D, Friend  V, Allowi  A, Lazdunski  M, Lingueglia E. Black mamba venom peptides target acid-sensing ion channels to abolish pain. Nature 2012;490:552\u20135. PubMed PMID: 23034652.","DOI":"10.1038\/nature11494"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_017","doi-asserted-by":"crossref","unstructured":"Lewis RJ, Garcia ML. Therapeutic potential of venom peptides. Nat Rev Drug Discov 2003;2:790\u2013802, 10\/\/print.","DOI":"10.1038\/nrd1197"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_018","doi-asserted-by":"crossref","unstructured":"Kasturiratne  A, Wickremasinghe AR, de Silva  N, Gunawardena NK, Pathmeswaran  A, Premaratna  R, Savioli  L, Lalloo DG, de Silva HJ. The global burden of snakebite: a literature analysis and modelling based on regional estimates of envenoming and deaths. PLoS Med 2008;5:e218. PubMed PMID: 18986210. Pubmed Central PMCID: PMC2577696.","DOI":"10.1371\/journal.pmed.0050218"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_019","doi-asserted-by":"crossref","unstructured":"Birklein  F, O\u2019Neill  D, Schlereth T. Complex regional pain syndrome: an optimistic perspective. Neurology 2014;84:89\u201396. PubMed PMID: 25471395.","DOI":"10.1212\/WNL.0000000000001095"},{"key":"2025120909564040569_j_j.sjpain.2015.07.005_ref_020","doi-asserted-by":"crossref","unstructured":"Chelimsky TC, Low PA, Naessens JM, Wilson PR, Amadio PC, O\u2019Brien PC. Value of autonomic testing in reflex sympathetic dystrophy. Mayo Clin Proc 1995;70:1029\u201340. PubMed PMID: 7475332. eng.","DOI":"10.4065\/70.11.1029"}],"container-title":["Scandinavian Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.degruyter.com\/view\/journals\/sjpain\/10\/1\/article-p15.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1877886015000841?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S1877886015000841?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1016\/j.sjpain.2015.07.005\/xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1016\/j.sjpain.2015.07.005\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T11:59:09Z","timestamp":1765281549000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.degruyterbrill.com\/document\/doi\/10.1016\/j.sjpain.2015.07.005\/html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,1]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,1,1]]},"published-print":{"date-parts":[[2016,1,1]]}},"alternative-id":["10.1016\/j.sjpain.2015.07.005"],"URL":"https:\/\/doi.org\/10.1016\/j.sjpain.2015.07.005","relation":{},"ISSN":["1877-8860","1877-8879"],"issn-type":[{"type":"print","value":"1877-8860"},{"type":"electronic","value":"1877-8879"}],"subject":[],"published":{"date-parts":[[2016,1,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Complex regional pain syndrome following viper-bite","name":"articletitle","label":"Article Title"},{"value":"Scandinavian Journal of Pain","name":"journaltitle","label":"Journal Title"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.sjpain.2015.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"http:\/\/dx.doi.org\/10.1016\/j.sjpain.2015.11.008","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Scandinavian Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}