{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:01:18Z","timestamp":1786996878423,"version":"build-2736575974"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","award":["LH2023H062"],"award-info":[{"award-number":["LH2023H062"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82174422"],"award-info":[{"award-number":["82174422"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82374509"],"award-info":[{"award-number":["82374509"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["slas-technology.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["SLAS Technology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.slast.2025.100356","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T18:27:33Z","timestamp":1759343253000},"page":"100356","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Evaluation of ovarian microvascular structure in PCOS patients based on high-resolution ultrasound imaging technology"],"prefix":"10.1016","volume":"35","author":[{"given":"Xianyi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoxu","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongying","family":"Kuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.slast.2025.100356_bib0001","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/RLI.0000000000000565","article-title":"Super-resolution contrast-enhanced ultrasound methodology for the identification of in vivo vascular dynamics in 2D[J]","volume":"54","author":"Kanoulas","year":"2019","journal-title":"Invest Radiol"},{"issue":"9","key":"10.1016\/j.slast.2025.100356_bib0002","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1016\/j.ultrasmedbio.2019.05.015","article-title":"Differentiation of vascular characteristics using contrast-enhanced ultrasound imaging[J]","volume":"45","author":"Butler","year":"2019","journal-title":"Ultrasound Med Biol"},{"issue":"10","key":"10.1016\/j.slast.2025.100356_bib0003","doi-asserted-by":"crossref","first-page":"2751","DOI":"10.1002\/jum.14983","article-title":"Evaluation of ovarian vascularity in children by using the \u201csuperb microvascular imaging\u201d ultrasound technique in comparison with conventional Doppler ultrasound techniques[J]","volume":"38","author":"Ayaz","year":"2019","journal-title":"J Ultrasound Med"},{"issue":"5","key":"10.1016\/j.slast.2025.100356_bib0004","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1002\/jcu.23210","article-title":"The clinical application of ultrasonography with superb microvascular imaging-a review[J]","volume":"50","author":"Tang","year":"2022","journal-title":"J Clin Ultrasound"},{"issue":"7","key":"10.1016\/j.slast.2025.100356_bib0005","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1111\/jdv.19939","article-title":"Seeing beyond skin deep: high-resolution ultrasound in dermatology\u2014a comprehensive review and future prospects[J]","volume":"38","author":"Liu","year":"2024","journal-title":"J Eur Acad Dermatol Venereol"},{"issue":"3","key":"10.1016\/j.slast.2025.100356_bib0006","first-page":"981","article-title":"Analysis and evaluation of ultrasound imaging features and pathological results of ovarian cancer[J]","volume":"11","author":"Zhang","year":"2021","journal-title":"J Med Imaging Health Inform"},{"issue":"8","key":"10.1016\/j.slast.2025.100356_bib0007","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1021\/acsphotonics.2c00440","article-title":"Current strategies of photoacoustic imaging assisted cancer theragnostics toward clinical studies[J]","volume":"9","author":"Li","year":"2022","journal-title":"ACS Photonics"},{"issue":"3","key":"10.1016\/j.slast.2025.100356_bib0008","doi-asserted-by":"crossref","first-page":"239","DOI":"10.3233\/CH-221487","article-title":"Ultrasound features of abdominal thrombosis in COVID 19 patients[J]","volume":"82","author":"Dong","year":"2022","journal-title":"Clin Hemorheol Microcirc"},{"issue":"S1","key":"10.1016\/j.slast.2025.100356_bib0009","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.29.S1.S11528","article-title":"Video-rate endocavity photoacoustic\/harmonic ultrasound imaging with miniaturized light delivery[J]","volume":"29","author":"Oh","year":"2024","journal-title":"J Biomed Opt"},{"issue":"1","key":"10.1016\/j.slast.2025.100356_bib0010","doi-asserted-by":"crossref","DOI":"10.1117\/1.JBO.30.1.016006","article-title":"Low-cost microvascular phantom for photoacoustic imaging using loofah[J]","volume":"30","author":"Xu","year":"2025","journal-title":"J Biomed Opt"},{"issue":"5","key":"10.1016\/j.slast.2025.100356_bib0011","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/uog.27454","article-title":"Serous surface papillary borderline ovarian tumors: correlation of sonographic features with clinic pathological findings[J]","volume":"63","author":"Wang","year":"2024","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.slast.2025.100356_bib0012","first-page":"1743","article-title":"Clinical diagnosis and treatment value of CT three-dimensional imaging of gynecological pelvic blood vessels[J]","volume":"11","author":"Qiao","year":"2021","journal-title":"J Med Imaging Health Inform"},{"issue":"6","key":"10.1016\/j.slast.2025.100356_bib0013","doi-asserted-by":"crossref","DOI":"10.1117\/1.JMI.8.6.066001","article-title":"Endocavity ultrasound and photoacoustic system for fetal and maternal imaging: design, implementation, and ex-vivo validation[J]","volume":"8","author":"Yan","year":"2021","journal-title":"J Med Imaging"},{"issue":"36","key":"10.1016\/j.slast.2025.100356_bib0014","doi-asserted-by":"crossref","first-page":"25144","DOI":"10.1021\/acsnano.4c06965","article-title":"Near-Infrared II agent with excellent overall performance for imaging-guided photothermal thrombolysis[J]","volume":"18","author":"Zhou","year":"2024","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.slast.2025.100356_bib0015","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/uog.29122","article-title":"Ultrasound assessment of the pelvic sidewall: methodological consensus opinion[J]","volume":"65","author":"Fischerova","year":"2025","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.slast.2025.100356_bib0016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s11671-024-04173-8","article-title":"A comprehensive review on nanoparticle-based photo acoustic: current application and future prospective[J]","volume":"19","author":"Panja","year":"2024","journal-title":"Discover Nano"},{"issue":"7","key":"10.1016\/j.slast.2025.100356_bib0017","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1111\/aogs.14585","article-title":"Novel application to evaluate endometrial blood flow using transvaginal superb microvascular imaging: a preliminary study describing physiological changes from ovulation to mid-luteal phase[J]","volume":"102","author":"Mitao","year":"2023","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"11","key":"10.1016\/j.slast.2025.100356_bib0018","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1111\/aogs.14914","article-title":"Microvascular flow imaging of fibroids: a prospective pilot study[J]","volume":"103","author":"Frijlingh","year":"2024","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"6","key":"10.1016\/j.slast.2025.100356_bib0019","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/s41571-022-00615-3","article-title":"The emerging role of photoacoustic imaging in clinical oncology[J]","volume":"19","author":"Lin","year":"2022","journal-title":"Nat Rev Clin Oncol"},{"issue":"2","key":"10.1016\/j.slast.2025.100356_bib0020","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/uog.23654","article-title":"Preoperative staging of ovarian cancer: comparison between ultrasound, CT and whole-body diffusion-weighted MRI (ISAAC study)[J]","volume":"59","author":"Fischerova","year":"2022","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"12","key":"10.1016\/j.slast.2025.100356_bib0021","doi-asserted-by":"crossref","first-page":"6010","DOI":"10.1021\/acs.molpharmaceut.3c00708","article-title":"Nanotheranostics: molecular diagnostics and nanotherapeutic evaluation by photoacoustic\/ultrasound imaging in small animals[J]","volume":"20","author":"Dhamija","year":"2023","journal-title":"Mol Pharm"},{"issue":"4","key":"10.1016\/j.slast.2025.100356_bib0022","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1364\/BOE.420724","article-title":"Multi-spectral intravascular photoacoustic\/ultrasound\/optical coherence tomography tri-modality system with a fully-integrated 0.9-mm full field-of-view catheter for plaque vulnerability imaging[J]","volume":"12","author":"Leng","year":"2021","journal-title":"Biomed Opt Express"},{"issue":"9 Part 1","key":"10.1016\/j.slast.2025.100356_bib0023","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.36740\/WLek202209110","article-title":"Peculiarities of vasor-regulating functions of the vascular endothelium in adaptation of the youth body to systematic physical loads[J]","volume":"75","author":"Tyshchenko","year":"2022","journal-title":"Wiadomosci lekarskie"},{"issue":"6","key":"10.1016\/j.slast.2025.100356_bib0024","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/s41574-021-00482-5","article-title":"Optoacoustic imaging in endocrinology and metabolism[J]","volume":"17","author":"Karlas","year":"2021","journal-title":"Nat Rev Endocrinol"},{"issue":"11","key":"10.1016\/j.slast.2025.100356_bib0025","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1007\/s11547-022-01553-x","article-title":"4D flow MRI in the portal venous system: imaging and analysis methods, and clinical applications[J]","volume":"127","author":"Hyodo","year":"2022","journal-title":"Radiol Med"},{"issue":"5","key":"10.1016\/j.slast.2025.100356_bib0026","first-page":"1023","article-title":"An ultrasound imaging and computational fluid dynamics protocol to assess hemodynamics in iliac vein compression syndrome[J]","volume":"11","author":"Assi","year":"2023","journal-title":"J Vasc Surg"},{"issue":"5","key":"10.1016\/j.slast.2025.100356_bib0027","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1177\/15266028211025022","article-title":"Uterine arteriovenous malformation: a pictorial review of diagnosis and management[J]","volume":"28","author":"Hoang","year":"2021","journal-title":"J Endovasc Therapy"},{"issue":"5","key":"10.1016\/j.slast.2025.100356_bib0028","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1080\/01443615.2021.2004101","article-title":"Application of ultrasound markers measured at different time points of COH cycle in the prediction of ovarian response for individualised ovulation induction[J]","volume":"42","author":"Li","year":"2022","journal-title":"J Obstet Gynaecol (Lahore)"},{"issue":"11","key":"10.1016\/j.slast.2025.100356_bib0029","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/OGX.0000000000001325","article-title":"Autologous ovarian tissue transplantation: preoperative assessment and preparation of the patient[J]","volume":"79","author":"Turan","year":"2024","journal-title":"Obstet Gynecol Surv"},{"issue":"22","key":"10.1016\/j.slast.2025.100356_bib0030","doi-asserted-by":"crossref","first-page":"28011","DOI":"10.1021\/acsami.4c04913","article-title":"NIR-II fluorescence imaging for in vivo quantitative analysis[J]","volume":"16","author":"Chen","year":"2024","journal-title":"ACS Appl Mater Interfaces"},{"issue":"10","key":"10.1016\/j.slast.2025.100356_bib0031","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1021\/acssensors.2c01468","article-title":"Ultrasound molecular imaging and its applications in cancer diagnosis and therapy[J]","volume":"7","author":"Zhang","year":"2022","journal-title":"ACS Sens"},{"issue":"1","key":"10.1016\/j.slast.2025.100356_bib0032","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11307-023-01827-4","article-title":"Current and developing lymphatic imaging approaches for elucidation of functional mechanisms and disease progression[J]","volume":"26","author":"Aron","year":"2024","journal-title":"Mol Imaging Biol"},{"issue":"1","key":"10.1016\/j.slast.2025.100356_bib0033","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.mric.2022.06.006","article-title":"MR imaging of endometriosis of the adnexa[J]","volume":"31","author":"Sakala","year":"2023","journal-title":"Magn Resonance Imaging Clin"},{"issue":"4","key":"10.1016\/j.slast.2025.100356_bib0034","doi-asserted-by":"crossref","DOI":"10.1117\/1.JOM.1.4.044502","article-title":"Triple-modality co-registered endoscope featuring wide-field reflectance imaging, and high-resolution multiphoton and optical coherence microscopy[J]","volume":"1","author":"Vega","year":"2021","journal-title":"J Opt Microsyst"},{"issue":"12","key":"10.1016\/j.slast.2025.100356_bib0035","doi-asserted-by":"crossref","first-page":"3735","DOI":"10.31635\/ccschem.022.202101547","article-title":"Small-molecule fluorophores for near-infrared IIb imaging and image-guided therapy of vascular diseases[J]","volume":"4","author":"Li","year":"2022","journal-title":"CCS Chem"},{"issue":"2","key":"10.1016\/j.slast.2025.100356_bib0036","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/RUQ.0000000000000537","article-title":"Liver stiffness is increased in polycystic ovary syndrome and related with complement C1q\/tumor necrosis factor\u2013Related protein 3 levels: a point shear wave elastography study[J]","volume":"37","author":"Gulumsek","year":"2021","journal-title":"Ultrasound Q"}],"container-title":["SLAS Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2472630325001153?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2472630325001153?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T16:47:38Z","timestamp":1775494058000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2472630325001153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":36,"alternative-id":["S2472630325001153"],"URL":"https:\/\/doi.org\/10.1016\/j.slast.2025.100356","relation":{},"ISSN":["2472-6303"],"issn-type":[{"value":"2472-6303","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of ovarian microvascular structure in PCOS patients based on high-resolution ultrasound imaging technology","name":"articletitle","label":"Article Title"},{"value":"SLAS Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.slast.2025.100356","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Society for Laboratory Automation and Screening.","name":"copyright","label":"Copyright"}],"article-number":"100356"}}