{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:35:39Z","timestamp":1791329739622,"version":"4.3.1"},"reference-count":90,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1016\/j.sleep.2007.08.012","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T09:09:43Z","timestamp":1196154583000},"page":"770-781","source":"Crossref","is-referenced-by-count":168,"title":["Early manifestations of restless legs syndrome in childhood and adolescence"],"prefix":"10.1016","volume":"9","author":[{"given":"Daniel L.","family":"Picchietti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna E.","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2007.08.012_bib1","unstructured":"Willis T, Eugenius P. The London practice of physick. London: Bassett, Dring, Harper, and Crook, 1692."},{"key":"10.1016\/j.sleep.2007.08.012_bib2","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1212\/WNL.10.9.868","article-title":"Restless legs syndrome","volume":"10","author":"Ekbom","year":"1960","journal-title":"Neurology"},{"issue":"11","key":"10.1016\/j.sleep.2007.08.012_bib3","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1001\/archinte.165.11.1286","article-title":"Restless legs syndrome prevalence and impact: REST general population study","volume":"165","author":"Allen","year":"2005","journal-title":"Arch Intern Med"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib4","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.sleep.2005.03.008","article-title":"Prevalence, severity and risk factors of restless legs syndrome in the general adult population in two Scandinavian countries","volume":"6","author":"Bjorvatn","year":"2005","journal-title":"Sleep Med"},{"issue":"11","key":"10.1016\/j.sleep.2007.08.012_bib5","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1212\/01.WNL.0000163996.64461.A3","article-title":"Restless legs syndrome: a community-based study of prevalence, severity, and risk factors","volume":"64","author":"Hogl","year":"2005","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib6","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1212\/01.wnl.0000168910.48309.4a","article-title":"Epidemiology of restless legs syndrome in French adults: a nationwide survey: the INSTANT Study","volume":"65","author":"Tison","year":"2005","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib7","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1001\/archinte.164.2.196","article-title":"Sex and the risk of restless legs syndrome in the general population","volume":"164","author":"Berger","year":"2004","journal-title":"Arch Intern Med"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib8","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000050750","article-title":"Restless Legs Syndrome among working-aged women","volume":"46","author":"Ulfberg","year":"2001","journal-title":"Eur Neurol"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib9","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1002\/mds.1209","article-title":"Prevalence of restless legs syndrome among men aged 18 to 64 years: an association with somatic disease and neuropsychiatric symptoms","volume":"16","author":"Ulfberg","year":"2001","journal-title":"Mov Disord"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib10","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.sleep.2004.03.006","article-title":"Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care study","volume":"5","author":"Hening","year":"2004","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib11","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.sleep.2004.07.003","article-title":"Epidemiology of restless legs syndrome as diagnosed in UK primary care","volume":"5","author":"Van De Vijver","year":"2004","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib12","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1212\/WNL.46.1.92","article-title":"A questionnaire study of 138 patients with restless legs syndrome: the \u2018Night-Walkers\u2019 survey","volume":"46","author":"Walters","year":"1996","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/mds.870120111","article-title":"Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria","volume":"12","author":"Montplaisir","year":"1997","journal-title":"Mov Disord"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib14","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1159\/000052098","article-title":"Restless legs syndrome: a clinical study of 55 patients","volume":"45","author":"Bassetti","year":"2001","journal-title":"Eur Neurol"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib15","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0887-8994(94)90110-4","article-title":"Restless legs syndrome in childhood and adolescence","volume":"11","author":"Walters","year":"1994","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.sleep.2007.08.012_bib16","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S1056-4993(18)30359-6","article-title":"Restless legs syndrome and periodic limb movement disorder in children and adolescents: comorbidity with attention-deficit hyperactivity disorder","volume":"5","author":"Picchietti","year":"1996","journal-title":"Child Adoles Psych Clinics North Amer"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib17","first-page":"213","article-title":"Associations between symptoms of inattention, hyperactivity, restless legs, and periodic leg movements","volume":"25","author":"Chervin","year":"2002","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib18","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1002\/ana.20292","article-title":"Childhood-onset restless legs syndrome","volume":"56","author":"Kotagal","year":"2004","journal-title":"Ann Neurol"},{"key":"10.1016\/j.sleep.2007.08.012_bib19","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.pediatrneurol.2004.11.007","article-title":"Ropinirole in a child with attention-deficit hyperactivity disorder and restless legs syndrome","volume":"32","author":"Konofal","year":"2005","journal-title":"Pediatr Neurol"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib20","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1542\/peds.111.1.e17","article-title":"Sleepwalking and sleep terrors in prepubertal children: what triggers them?","volume":"111","author":"Guilleminault","year":"2003","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib21","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1055\/s-2005-837685","article-title":"Restless legs syndrome and sleep problems in children and adolescents with insulin-dependent diabetes mellitus type 1","volume":"36","author":"Happe","year":"2005","journal-title":"Neuropediatrics"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib22","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1389-9457(01)00160-5","article-title":"Low body stores of iron and restless legs syndrome: a correctable cause of insomnia in adolescents and teenagers","volume":"3","author":"Kryger","year":"2002","journal-title":"Sleep Med"},{"issue":"12","key":"10.1016\/j.sleep.2007.08.012_bib23","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1177\/088307389801301202","article-title":"Periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder","volume":"13","author":"Picchietti","year":"1998","journal-title":"J Child Neurol"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib24","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1002\/1531-8257(199911)14:6<1000::AID-MDS1014>3.0.CO;2-P","article-title":"Further studies on periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder","volume":"14","author":"Picchietti","year":"1999","journal-title":"Mov Disord"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib25","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1093\/sleep\/22.3.297","article-title":"Moderate to severe periodic limb movement disorder in childhood and adolescence","volume":"22","author":"Picchietti","year":"1999","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib26","first-page":"767","article-title":"Some children with growing pains may actually have restless legs syndrome","volume":"27","author":"Rajaram","year":"2004","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib27","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1542\/peds.2006-2767","article-title":"Restless legs syndrome: prevalence and impact in children and adolescents \u2013 the Peds REST study","volume":"120","author":"Picchietti","year":"2007","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib28","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1389-9457(03)00010-8","article-title":"Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health","volume":"4","author":"Allen","year":"2003","journal-title":"Sleep Med"},{"issue":"21","key":"10.1016\/j.sleep.2007.08.012_bib29","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1056\/NEJMcp021288","article-title":"Clinical practice. Restless legs syndrome","volume":"348","author":"Earley","year":"2003","journal-title":"N Engl J Med"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib30","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1016\/S0149-2918(04)90136-1","article-title":"Evaluating the quality of life of patients with restless legs syndrome","volume":"26","author":"Abetz","year":"2004","journal-title":"Clin Ther"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib31","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.sleep.2005.05.006","article-title":"Cognitive deficits associated with restless legs syndrome (RLS)","volume":"7","author":"Pearson","year":"2006","journal-title":"Sleep Med"},{"issue":"Suppl. 2","key":"10.1016\/j.sleep.2007.08.012_bib32","first-page":"50","article-title":"The impact of restless legs syndrome (RLS) on sleep and cognitive function","volume":"9","author":"Abetz","year":"2004","journal-title":"Eur J Neurol"},{"issue":"8","key":"10.1016\/j.sleep.2007.08.012_bib33","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1093\/sleep\/27.8.1499","article-title":"Symptoms of attention-deficit\/hyperactivity disorder in adults with restless legs syndrome","volume":"27","author":"Wagner","year":"2004","journal-title":"Sleep"},{"issue":"7","key":"10.1016\/j.sleep.2007.08.012_bib34","first-page":"891","article-title":"Restless legs syndrome, periodic limb movements in sleep, and depression","volume":"28","author":"Picchietti","year":"2005","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib35","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/sleep\/23.5.1b","article-title":"Clinical characteristics and frequency of the hereditary restless legs syndrome in a population of 300 patients","volume":"23","author":"Winkelmann","year":"2000","journal-title":"Sleep"},{"issue":"15","key":"10.1016\/j.sleep.2007.08.012_bib36","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1212\/01.wnl.0000259036.89411.52","article-title":"Nocturnal blood pressure changes in patients with restless legs syndrome","volume":"68","author":"Pennestri","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2007.08.012_bib37","unstructured":"American Academy of Sleep Medicine. International classification of sleep disorders, second edition: Diagnostic and coding manual. Westchester, IL: American Academy of Sleep Medicine, 2005."},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib38","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1002\/mds.870100517","article-title":"Toward a better definition of the restless legs syndrome. The International Restless Legs Syndrome Study Group","volume":"10","author":"Walters","year":"1995","journal-title":"Mov Disord"},{"key":"10.1016\/j.sleep.2007.08.012_bib39","series-title":"International classification of sleep disorders, revised: Diagnostic and coding manual","author":"ASDA","year":"1997"},{"key":"10.1016\/j.sleep.2007.08.012_bib40","unstructured":"American Psychiatric Association., American Psychiatric Association. Task Force on DSM-IV. Diagnostic and statistical manual of mental disorders: DSM-IV. Washington, DC: American Psychiatric Association; 1994."},{"key":"10.1016\/j.sleep.2007.08.012_bib41","unstructured":"The Atlas Task Force. Recording and scoring leg movements. Sleep 1993;16 (8):748\u201359."},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib42","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1002\/mds.870110407","article-title":"Clinical symptoms and possible anticipation in a large kindred of familial restless legs syndrome","volume":"11","author":"Trenkwalder","year":"1996","journal-title":"Mov Disord"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1389-9457(99)00012-X","article-title":"Defining the phenotype of the restless legs syndrome (RLS) using age-of-symptom-onset","volume":"1","author":"Allen","year":"2000","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib44","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1002\/mds.10231","article-title":"Long-term course of restless legs syndrome in dialysis patients after kidney transplantation","volume":"17","author":"Winkelmann","year":"2002","journal-title":"Mov Disord"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib45","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1212\/01.WNL.0000138427.83574.A6","article-title":"Restless legs syndrome and pregnancy","volume":"63","author":"Manconi","year":"2004","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.sleep.2007.08.012_bib46","first-page":"739","article-title":"Restless legs syndrome and sleep bruxism: prevalence and association among Canadians","volume":"17","author":"Lavigne","year":"1994","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib47","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1212\/WNL.47.6.1435","article-title":"Restless legs syndrome: clinicoetiologic correlates","volume":"47","author":"Ondo","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2007.08.012_bib48","series-title":"Rudolph\u2019s pediatrics","author":"Rudolph","year":"2003"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib49","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S1389-9457(01)00164-2","article-title":"Is there a subpopulation of children with growing pains who really have Restless Legs Syndrome? A review of the literature","volume":"3","author":"Walters","year":"2002","journal-title":"Sleep Med"},{"issue":"8","key":"10.1016\/j.sleep.2007.08.012_bib50","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1093\/sleep\/28.8.1007","article-title":"Restless legs syndrome and attention-deficit\/hyperactivity disorder: a review of the literature","volume":"28","author":"Cortese","year":"2005","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib51","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s00415-005-0604-7","article-title":"\u201cAnxietas Tibiarum\u201d depression and anxiety disorders in patients with restless legs syndrome","volume":"252","author":"Winkelmann","year":"2005","journal-title":"J Neurol"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib52","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0006-3223(95)00188-3","article-title":"Sleep disturbance and psychiatric disorders: a longitudinal epidemiological study of young adults","volume":"39","author":"Breslau","year":"1996","journal-title":"Biol Psychiatry"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib53","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1093\/oxfordjournals.aje.a009241","article-title":"Insomnia in young men and subsequent depression. The Johns Hopkins Precursors Study","volume":"146","author":"Chang","year":"1997","journal-title":"Am J Epidemiol"},{"issue":"11","key":"10.1016\/j.sleep.2007.08.012_bib54","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/sleep\/28.11.1457","article-title":"Epidemiology of insomnia, depression, and anxiety","volume":"28","author":"Taylor","year":"2005","journal-title":"Sleep"},{"issue":"11","key":"10.1016\/j.sleep.2007.08.012_bib55","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1001\/jama.262.11.1479","article-title":"Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention?","volume":"262","author":"Ford","year":"1989","journal-title":"JAMA"},{"issue":"1\u20132","key":"10.1016\/j.sleep.2007.08.012_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2006.05.025","article-title":"Early childhood sleep and eating problems as predictors of adolescent and adult mood and anxiety disorders","volume":"96","author":"Ong","year":"2006","journal-title":"J Affect Disord"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib57","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s10802-005-1824-0","article-title":"Prospective longitudinal associations between persistent sleep problems in childhood and anxiety and depression disorders in adulthood","volume":"33","author":"Gregory","year":"2005","journal-title":"J Abnorm Child Psychol"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib58","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1053\/smrv.1999.0075","article-title":"Depression and insomnia: questions of cause and effect","volume":"4","author":"Lustberg","year":"2000","journal-title":"Sleep Med Rev"},{"issue":"10","key":"10.1016\/j.sleep.2007.08.012_bib59","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.4088\/JCP.v66n1008","article-title":"Sleep and depression","volume":"66","author":"Tsuno","year":"2005","journal-title":"J Clin Psychiatry"},{"issue":"11","key":"10.1016\/j.sleep.2007.08.012_bib60","first-page":"1362","article-title":"Insomnia and depression: if it looks and walks like a duck","volume":"28","author":"Turek","year":"2005","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib61","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1093\/sleep\/28.2.169","article-title":"Reduced extracellular dopamine and increased responsiveness to novelty: neurochemical and behavioral sequelae of intermittent hypoxia","volume":"28","author":"Decker","year":"2005","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib62","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1542\/peds.2005-1067","article-title":"Polysomnographic characteristics in normal preschool and early school-aged children","volume":"117","author":"Montgomery-Downs","year":"2006","journal-title":"Pediatrics"},{"issue":"9","key":"10.1016\/j.sleep.2007.08.012_bib63","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1093\/sleep\/29.9.1183","article-title":"PLMS and PLMW in healthy subjects as a function of age: prevalence and interval distribution","volume":"29","author":"Pennestri","year":"2006","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib64","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/ppul.20236","article-title":"Polysomnographic values in children 2\u20139 years old: additional data and review of the literature","volume":"40","author":"Traeger","year":"2005","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.sleep.2007.08.012_bib65","doi-asserted-by":"crossref","DOI":"10.1016\/j.sleep.2006.08.009","article-title":"Ethnic difference in periodic limb movements in children","author":"O\u2019Brien L","year":"2007","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib66","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1046\/j.1365-2869.2003.00332.x","article-title":"Periodic limb movement disorder of sleep in children","volume":"12","author":"Crabtree","year":"2003","journal-title":"J Sleep Res"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib67","doi-asserted-by":"crossref","first-page":"E70","DOI":"10.1542\/peds.106.5.e70","article-title":"Sleep and periodic limb movement in sleep in juvenile fibromyalgia","volume":"106","author":"Tayag-Kier","year":"2000","journal-title":"Pediatrics"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib68","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/S0022-3476(98)70110-6","article-title":"Periodic limb movement in sleep in children with Williams syndrome","volume":"133","author":"Arens","year":"1998","journal-title":"J Pediatr"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib69","doi-asserted-by":"crossref","first-page":"438","DOI":"10.5664\/jcsm.26661","article-title":"Prevalence and correlates of periodic limb movements in older women","volume":"2","author":"Claman","year":"2006","journal-title":"J Clin Sleep Med"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib70","doi-asserted-by":"crossref","first-page":"446","DOI":"10.5664\/jcsm.26662","article-title":"Periodic limb movements in sleep: irrelevant epiphenomenon, marker for a potential problem, or a disorder?","volume":"2","author":"Picchietti","year":"2006","journal-title":"J Clin Sleep Med"},{"issue":"8 Pt 1","key":"10.1016\/j.sleep.2007.08.012_bib71","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1164\/ajrccm.164.8.2107127b","article-title":"Con: assessment of periodic leg movements is not an essential component of an overnight sleep study","volume":"164","author":"Mahowald","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib72","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/s1389-9457(02)00238-1","article-title":"Can periodic limb movement disorder be diagnosed without polysomnography? A case-control study","volume":"4","author":"Hilbert","year":"2003","journal-title":"Sleep Med"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib73","first-page":"331","article-title":"Variability of periodic leg movements in various sleep disorders: implications for clinical and pathophysiologic studies","volume":"28","author":"Hornyak","year":"2005","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib74","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.sleep.2004.12.010","article-title":"The validation of a new actigraphy system for the measurement of periodic leg movements in sleep","volume":"6","author":"King","year":"2005","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib75","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.sleep.2005.01.004","article-title":"The PAM-RL ambulatory device for detection of periodic leg movements: a validation study","volume":"6","author":"Sforza","year":"2005","journal-title":"Sleep Med"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib76","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/ageing\/23.3.200","article-title":"Iron status and restless legs syndrome in the elderly","volume":"23","author":"O\u2019Keeffe","year":"1994","journal-title":"Age Ageing"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib77","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1093\/sleep\/21.4.381","article-title":"Iron and the restless legs syndrome","volume":"21","author":"Sun","year":"1998","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2007.08.012_bib78","doi-asserted-by":"crossref","DOI":"10.1016\/j.sleep.2006.10.004","article-title":"Restless legs syndrome in Indian patients having iron deficiency anemia in a tertiary care hospital","author":"Rangarajan","year":"2007","journal-title":"Sleep Med"},{"issue":"2","key":"10.1016\/j.sleep.2007.08.012_bib79","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.sleep.2003.09.010","article-title":"Restless legs syndrome in blood donors","volume":"5","author":"Ulfberg","year":"2004","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib80","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.sleep.2005.11.009","article-title":"MRI-determined regional brain iron concentrations in early- and late-onset restless legs syndrome","volume":"7","author":"Earley","year":"2006","journal-title":"Sleep Med"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib81","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1212\/01.WNL.0000078887.16593.12","article-title":"Neuropathological examination suggests impaired brain iron acquisition in restless legs syndrome","volume":"61","author":"Connor","year":"2003","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.sleep.2007.08.012_bib82","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.sleep.2004.03.002","article-title":"The treatment of restless legs syndrome with intravenous iron dextran","volume":"5","author":"Earley","year":"2004","journal-title":"Sleep Med"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib83","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.sleep.2005.01.008","article-title":"Repeated IV doses of iron provides effective supplemental treatment of restless legs syndrome","volume":"6","author":"Earley","year":"2005","journal-title":"Sleep Med"},{"issue":"6","key":"10.1016\/j.sleep.2007.08.012_bib84","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/sleep\/26.6.735","article-title":"Periodic limb movements in sleep and iron status in children","volume":"26","author":"Simakajornboon","year":"2003","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.sleep.2007.08.012_bib85","doi-asserted-by":"crossref","first-page":"e732","DOI":"10.1542\/peds.2005-0715","article-title":"Effectiveness of iron supplementation in a young child with attention-deficit\/hyperactivity disorder","volume":"116","author":"Konofal","year":"2005","journal-title":"Pediatrics"},{"issue":"12","key":"10.1016\/j.sleep.2007.08.012_bib86","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1001\/archpedi.158.12.1113","article-title":"Iron deficiency in children with attention-deficit\/hyperactivity disorder","volume":"158","author":"Konofal","year":"2004","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib87","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.sleep.2004.01.012","article-title":"Dopamine and iron in the pathophysiology of restless legs syndrome (RLS)","volume":"5","author":"Allen","year":"2004","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2007.08.012_bib88","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1146\/annurev.nutr.23.020102.075739","article-title":"Iron status and neural functioning","volume":"23","author":"Beard","year":"2003","journal-title":"Annu Rev Nutr"},{"issue":"1","key":"10.1016\/j.sleep.2007.08.012_bib89","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1600-0609.1994.tb00173.x","article-title":"Serum ferritin in children and adolescents Results from population surveys in 1979 and 1986 comprising 1312 individuals","volume":"53","author":"Milman","year":"1994","journal-title":"Eur J Haematol"},{"issue":"4","key":"10.1016\/j.sleep.2007.08.012_bib90","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/j.1600-0609.1999.tb01883.x","article-title":"A longitudinal study of serum ferritin in 319 adolescent Danish boys and girls examined in and","volume":"63","author":"Milman","year":"1999","journal-title":"Eur J Haematol"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945707003139?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945707003139?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T17:25:54Z","timestamp":1588094754000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945707003139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":90,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["S1389945707003139"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2007.08.012","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}