{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:10:59Z","timestamp":1788999059022,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.sleep.2011.05.007","type":"journal-article","created":{"date-parts":[[2011,10,31]],"date-time":"2011-10-31T02:55:07Z","timestamp":1320029707000},"page":"947-951","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Familial aggregation of narcolepsy"],"prefix":"10.1016","volume":"12","author":[{"given":"Yun-Kwok","family":"Wing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siu-Ping","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert M.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson L.S.","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret H.L.","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk-Hang","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crover K.W.","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Mok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho-Wan","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Ho-Ming","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiu-Shuen","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.K.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2011.05.007_b0005","unstructured":"American Academy of Sleep Medicine. The International Classification of Sleep Disorders, 2nd ed: Diagnostic and coding manual. Westchester, Illinois: American Academy of Sleep Medicine; 2005."},{"key":"10.1016\/j.sleep.2011.05.007_b0010","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1136\/jnnp.2007.143420","article-title":"Narcolepsy in southern Chinese patients: clinical characteristics, HLA typing and seasonality of birth","volume":"79","author":"Wing","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.sleep.2011.05.007_b0015","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/sleep\/30.1.13","article-title":"The epidemiology of Narcolepsy","volume":"30","author":"Longstreth","year":"2007","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0020","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1001\/archneur.59.10.1553","article-title":"The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias","volume":"59","author":"Mignot","year":"2002","journal-title":"Arch Neurol"},{"key":"10.1016\/j.sleep.2011.05.007_b0025","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1136\/jnnp.74.12.1667","article-title":"CSF hypocretin-1 levels in narcolepsy, Kleine-Levin syndrome, and other hypersomnias and neurological conditions","volume":"74","author":"Dauvilliers","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.sleep.2011.05.007_b0030","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1212\/WNL.57.12.2253","article-title":"CSF hypocretin\/orexin levels in narcolepsy and other neurological conditions","volume":"57","author":"Ripley","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2011.05.007_b0035","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1136\/jnnp.2005.067207","article-title":"Hypocretin (orexin) deficiency predicts severe objective excessive daytime sleepiness in narcolepsy with cataplexy","volume":"77","author":"Baumann","year":"2006","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.sleep.2011.05.007_b0040","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S1474-4422(08)70140-6","article-title":"CSF hypocretin-1 assessment in sleep and neurological disorders","volume":"7","author":"Bourgin","year":"2008","journal-title":"Lancet Neurol"},{"issue":"2","key":"10.1016\/j.sleep.2011.05.007_b0045","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1093\/sleep\/33.2.169","article-title":"Validation of the ICSD-2 criteria for CSF hypocretin-1 measurements in the diagnosis of narcolepsy in the Danish population","volume":"33","author":"Knudsen","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0050","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1093\/sleep\/25.7.733","article-title":"Hypocretin (orexine) levels in cerebrospinal fluid of patients with narcolepsy: relationship to cataplexy and HLA DQB1\u22170602 status","volume":"25","author":"Krahn","year":"2002","journal-title":"Sleep"},{"issue":"2 Suppl. 1","key":"10.1016\/j.sleep.2011.05.007_b0055","first-page":"S16","article-title":"Genetic and familial aspects of narcolepsy","volume":"50","author":"Mignot","year":"1998","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2011.05.007_b0060","unstructured":"Kessler S, Guilleminault C, Dement W, Passouant P. Narcolepsy. New York: Spectrum; 1976. Genetic factors in narcolepsy; 285\u2013302."},{"key":"10.1016\/j.sleep.2011.05.007_b0065","unstructured":"Honda Y, Asaka A, Tanimura M, Furusho T. A genetic study of narcolepsy and excessive daytime sleepiness in 308 families with narcolepsy or hypersomnia probands. In: Guilleminault C, Lugaresi E, eds. Sleep Wake Disorders Natural History, Epidemiology and Long Term Evolution. New York, NY: Raven Press; 1983:187\u2013199."},{"key":"10.1016\/j.sleep.2011.05.007_b0070","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/S0140-6736(89)91977-6","article-title":"Familial patterns of narcolepsy","volume":"2","author":"Guilleminault","year":"1989","journal-title":"Lancet"},{"key":"10.1016\/j.sleep.2011.05.007_b0075","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1111\/j.1600-0404.1991.tb03969.x","article-title":"Familial narcolepsy in Finland","volume":"83","author":"Hublin","year":"1991","journal-title":"Acta Neurol Scand"},{"issue":"8 Suppl.","key":"10.1016\/j.sleep.2011.05.007_b0080","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1093\/sleep\/17.suppl_8.S54","article-title":"Family studies in narcolepsy","volume":"17","author":"Billiard","year":"1994","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0085","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1093\/sleep\/20.11.1021","article-title":"Familial aspects of narcolepsy\u2013cataplexy in the Czech Republic","volume":"20","author":"Nevsimalova","year":"1997","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0090","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1365-2869.1998.00105.x","article-title":"Segregation of HLA genes in multicase narcolepsy families","volume":"7","author":"Mayer","year":"1998","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2011.05.007_b0095","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1111\/j.1365-2869.2005.00476.x","article-title":"Frequency of narcolepsy symptoms and other sleep disorders in narcoleptic patients and their first-degree relatives","volume":"14","author":"Ohayon","year":"2005","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2011.05.007_b0100","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1093\/sleep\/20.10.850","article-title":"HLA haplotypes, polysomnography, and pedigrees in a case series of patients with narcolepsy","volume":"20","author":"Hayduk","year":"1997","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0105","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1093\/sleep\/30.7.851","article-title":"The familial risk and HLA susceptibility among narcolepsy patients in Hong Kong Chinese","volume":"30","author":"Chen","year":"2007","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0110","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/ana.10162","article-title":"The prevalence of narcolepsy among Chinese in Hong Kong","volume":"51","author":"Wing","year":"2002","journal-title":"Ann Neurol"},{"issue":"7","key":"10.1016\/j.sleep.2011.05.007_b0115","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1093\/sleep\/29.7.890","article-title":"The prevalence of multiple sleep-onset REM periods in a population-based sample","volume":"29","author":"Singh","year":"2006","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0120","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1093\/brain\/awl079","article-title":"Correlates of sleep-onset REM periods during the Multiple Sleep Latency Test in community adults","volume":"129","author":"Mignot","year":"2006","journal-title":"Brain"},{"issue":"6","key":"10.1016\/j.sleep.2011.05.007_b0125","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1093\/sleep\/33.6.774","article-title":"Prevalence and correlates of recurrent nightmares: A community-based two-phase study","volume":"33","author":"Li","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0130","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0022-3999(00)00179-3","article-title":"A validity study of Ullanlinna Narcolepsy Scale in Hong Kong Chinese","volume":"49","author":"Wing","year":"2000","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.sleep.2011.05.007_b0135","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jpsychores.2004.05.004","article-title":"Comparing MSLT and ESS in the measurement of excessive daytime sleepiness in obstructive sleep apnea syndrome","volume":"58","author":"Fong","year":"2005","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.sleep.2011.05.007_b0140","unstructured":"Rechtschaffen A, Kales A. A manual of standardised terminology, techniques and scoring system for sleep stages of human subjects UCLA, Los Angeles: NIH Publication 204. Brain Research Institute; 1973."},{"key":"10.1016\/j.sleep.2011.05.007_b0145","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/sleep\/9.4.519","article-title":"Guidelines for the multiple sleep latency test (MSLT): a standard measure of sleepiness","volume":"9","author":"Carskadon","year":"1986","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2011.05.007_b0150","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/WNP.0b013e31817f36a6","article-title":"Inter-rater and Intra-rater reliability in Multiple Sleep Latency Test","volume":"25","author":"Chen","year":"2008","journal-title":"J Clin Neurophysiol"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945711002644?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945711002644?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T15:07:38Z","timestamp":1761404858000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945711002644"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S1389945711002644"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2011.05.007","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Familial aggregation of narcolepsy","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2011.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}