{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T04:45:26Z","timestamp":1770439526818,"version":"3.49.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"crossref","award":["PG\/06\/092\/21267"],"award-info":[{"award-number":["PG\/06\/092\/21267"]}],"id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.sleep.2013.01.001","type":"journal-article","created":{"date-parts":[[2013,2,23]],"date-time":"2013-02-23T02:12:21Z","timestamp":1361585541000},"page":"428-432","source":"Crossref","is-referenced-by-count":23,"title":["Arterial stiffness and endothelial function in obstructive sleep apnoea\/hypopnoea syndrome"],"prefix":"10.1016","volume":"14","author":[{"given":"Anne","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjorie","family":"Vennelle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Connell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham","family":"McKillop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E.","family":"Newby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil J.","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata L.","family":"Riha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2013.01.001_b0005","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The occurrence of sleep-disordered breathing among middle-aged adults","volume":"328","author":"Young","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0010","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1164\/rccm.2109080","article-title":"Epidemiology of obstructive sleep apnea: a population health perspective","volume":"165","author":"Young","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"issue":"Suppl. 2","key":"10.1016\/j.sleep.2013.01.001_b0015","first-page":"ii45","article-title":"Sleep apnoea and hypertension: proof at last?","volume":"56","author":"Stradling","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.sleep.2013.01.001_b0020","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/S0140-6736(05)74229-X","article-title":"Long-term cardiovascular outcomes in men with obstructive sleep apnoea\u2013hypopnoea with or without treatment with continuous positive airway pressure: an observational study","volume":"365","author":"Marin","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.sleep.2013.01.001_b0025","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1164\/ajrccm.163.1.2001008","article-title":"Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study","volume":"163","author":"Shahar","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0030","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1164\/rccm.2105124","article-title":"Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-up","volume":"166","author":"Peker","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0035","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1183\/09031936.06.00107805","article-title":"Increased incidence of coronary artery disease in sleep apnoea: a long-term follow-up","volume":"28","author":"Peker","year":"2006","journal-title":"Eur Respir J"},{"key":"10.1016\/j.sleep.2013.01.001_b0040","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1164\/rccm.200505-702OC","article-title":"Association of sleep-disordered breathing and the occurrence of stroke","volume":"172","author":"Arzt","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0045","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1152\/jappl.1993.74.3.1123","article-title":"Arterial blood pressure responses to graded transient arousal from sleep in normal humans","volume":"74","author":"Davies","year":"1993","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.sleep.2013.01.001_b0050","first-page":"850","article-title":"Arterial stiffness increases during obstructive sleep apneas","volume":"25","author":"Jelic","year":"2002","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2013.01.001_b0055","doi-asserted-by":"crossref","first-page":"S529","DOI":"10.1097\/00004872-198812040-00166","article-title":"Is high and fluctuating muscle nerve sympathetic activity in the sleep apnoea syndrome of pathogenetic importance for the development of hypertension?","volume":"6","author":"Hedner","year":"1988","journal-title":"J Hypertens Suppl"},{"key":"10.1016\/j.sleep.2013.01.001_b0060","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1164\/rccm.200503-340OC","article-title":"Early signs of atherosclerosis in obstructive sleep apnea","volume":"172","author":"Drager","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0065","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1164\/rccm.200306-767OC","article-title":"Endothelial function in obstructive sleep apnea and response to treatment","volume":"169","author":"Ip","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0070","doi-asserted-by":"crossref","first-page":"2607","DOI":"10.1161\/01.CIR.102.21.2607","article-title":"Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apnea","volume":"102","author":"Kato","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.sleep.2013.01.001_b0075","series-title":"A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects","year":"1968"},{"key":"10.1016\/j.sleep.2013.01.001_b0080","series-title":"The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications","article-title":"Quan SF for the American Academy of Sleep Medicine","author":"Iber","year":"2007"},{"key":"10.1016\/j.sleep.2013.01.001_b0085","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.1093\/eurheartj\/ehl254","article-title":"European network for non-invasive investigation of large arteries. Expert consensus document on arterial stiffness: methodological issues and clinical applications","volume":"27","author":"Laurent","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.sleep.2013.01.001_b0090","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1161\/01.CIR.95.7.1827","article-title":"Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function","volume":"95","author":"Chen","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.sleep.2013.01.001_b0095","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0895-7061(01)02252-X","article-title":"Heart rate dependency of pulse pressure amplification and arterial stiffness","volume":"15","author":"Wilkinson","year":"2002","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.sleep.2013.01.001_b0100","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1161\/hq0102.101770","article-title":"Pulse-wave analysis: clinical evaluation of a noninvasive, widely applicable method for assessing endothelial function","volume":"22","author":"Wilkinson","year":"2002","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.sleep.2013.01.001_b0105","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0735-1097(02)01991-5","article-title":"Assessment of endothelial function using peripheral waveform analysis: a clinical application","volume":"40","author":"Hayward","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.sleep.2013.01.001_b0110","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1365-2125.2004.02334.x","article-title":"Comparative effects of glyceryl trinitrate and amyl nitrite on pulse wave reflection and augmentation index","volume":"59","author":"Greig","year":"2005","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.sleep.2013.01.001_b0115","unstructured":"AtCor Medical. Instructions for PWV measurements, <http:\/\/atcormedical.com> [accessed 10\/10\/2007]."},{"key":"10.1016\/j.sleep.2013.01.001_b0120","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s11325-010-0465-x","article-title":"Treatment of obstructive sleep apnea reduces arterial stiffness","volume":"16","author":"Buchner","year":"2012","journal-title":"Sleep Breath"},{"key":"10.1016\/j.sleep.2013.01.001_b0125","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1164\/rccm.200805-717OC","article-title":"Endothelial function and arterial stiffness in minimally symptomatic obstructive sleep apnea","volume":"178","author":"Kohler","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0130","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1291\/hypres.31.1109","article-title":"Aortic pressure augmentation as a marker of cardiovascular risk in obstructive sleep apnea syndrome","volume":"31","author":"Noda","year":"2008","journal-title":"Hypertens Res"},{"key":"10.1016\/j.sleep.2013.01.001_b0135","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1093\/eurheartj\/ehq024","article-title":"Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis","volume":"31","author":"Vlachopoulos","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.sleep.2013.01.001_b0140","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/hr.2010.200","article-title":"Increased arterial stiffness in obstructive sleep apnea: a systematic review","volume":"34","author":"Doonan","year":"2011","journal-title":"Hypertens Res"},{"key":"10.1016\/j.sleep.2013.01.001_b0145","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1093\/eurheartj\/ehq165","article-title":"Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: \u2018establishing normal and reference values\u2019","volume":"31","year":"2010","journal-title":"Eur Heart J"},{"key":"10.1016\/j.sleep.2013.01.001_b0150","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1378\/chest.10-2799","article-title":"The effect of simulated obstructive apnea and hypopnea on aortic diameter and BP","volume":"140","author":"St\u00f6whas","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.sleep.2013.01.001_b0155","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.jacc.2008.05.039","article-title":"Obstructive sleep apnea is associated with greater thoracic aorta size","volume":"52","author":"Serizawa","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.sleep.2013.01.001_b0160","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/j.1540-8175.2009.00957.x","article-title":"Effect of continuous positive airway pressure therapy on aortic stiffness in patients with obstructive sleep apnea syndrome","volume":"26","author":"Keles","year":"2009","journal-title":"Echocardiography"},{"key":"10.1016\/j.sleep.2013.01.001_b0165","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.echo.2006.09.005","article-title":"The relationship between aortic stiffness and cardiac function in patients with obstructive sleep apnea, independently from systemic hypertension","volume":"20","author":"Tavil","year":"2007","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.sleep.2013.01.001_b0170","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/sleep\/33.9.1173","article-title":"The relative impact of obstructive sleep apnea and hypertension on the structural and functional changes of the thoracic aorta","volume":"33","author":"Lee","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2013.01.001_b0175","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/00004872-199605000-00006","article-title":"Attenuated endothelium-dependent vascular relaxation in patients with sleep apnoea","volume":"14","author":"Carlson","year":"1996","journal-title":"J Hypertens"},{"key":"10.1016\/j.sleep.2013.01.001_b0180","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1164\/ajrccm.165.7.2102003","article-title":"Impaired vasodilator responses in obstructive sleep apnea are improved with continuous positive airway pressure therapy","volume":"165","author":"Imadojemu","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2013.01.001_b0185","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1093\/sleep\/32.10.1257","article-title":"Endothelial function in normotensive men with obstructive sleep apnea before and 6 months after CPAP treatment","volume":"32","author":"Bayram","year":"2009","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2013.01.001_b0190","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1159\/000323266","article-title":"Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy","volume":"82","author":"Buchner","year":"2011","journal-title":"Respiration"},{"key":"10.1016\/j.sleep.2013.01.001_b0195","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1183\/09031936.00086608","article-title":"Molecular mechanisms of cardiovascular disease in OSAHS: the oxidative stress link","volume":"33","author":"Lavie","year":"2009","journal-title":"Eur Respir J"},{"key":"10.1016\/j.sleep.2013.01.001_b0200","doi-asserted-by":"crossref","first-page":"3701","DOI":"10.1210\/jc.2009-1779","article-title":"Neck circumference as a novel measure of cardiometabolic risk: the Framingham heart study","volume":"95","author":"Preis","year":"2010","journal-title":"J Clin Endocrinol Metab"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945713000117?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945713000117?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T01:49:47Z","timestamp":1562723387000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945713000117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S1389945713000117"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2013.01.001","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}