{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:59:07Z","timestamp":1790521147806,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["sleep-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.sleep.2014.04.020","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T17:03:13Z","timestamp":1401901393000},"page":"1046-1054","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Impact of acute administration of sodium oxybate on nocturnal sleep polysomnography and on multiple sleep latency test in narcolepsy with cataplexy"],"prefix":"10.1016","volume":"15","author":[{"given":"Giuseppe","family":"Plazzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Pizza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Vandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora","family":"Aric\u00f2","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2207-1398","authenticated-orcid":false,"given":"Oliviero","family":"Bruni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Dauvilliers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaele","family":"Ferri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2014.04.020_bib0010","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.sleep.2010.07.008","article-title":"A 5-year prospective cohort study on health-related quality of life in patients with narcolepsy","volume":"12","author":"Vignatelli","year":"2011","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0015","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.smrv.2007.08.010","article-title":"Nocturnal aspects of narcolepsy with cataplexy","volume":"12","author":"Plazzi","year":"2008","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2014.04.020_bib0020","series-title":"Diagnostic and coding manual","article-title":"International classification of sleep disorders","author":"American Academy of Sleep Medicine","year":"2005"},{"key":"10.1016\/j.sleep.2014.04.020_bib0025","series-title":"Narcolepsy. Proceedings of the first international symposium on narcolepsy, July 1975","first-page":"43","article-title":"Disturbed nocturnal sleep","author":"Montplaisir","year":"1976"},{"key":"10.1016\/j.sleep.2014.04.020_bib0030","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.5665\/SLEEP.1280","article-title":"Narcolepsy with cataplexy associated with nocturnal compulsive behaviors: a case\u2013control study","volume":"34","author":"Palaia","year":"2011","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0035","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1111\/j.1365-2869.2004.00422.x","article-title":"The clinical spectrum of narcolepsy with cataplexy: a reappraisal","volume":"13","author":"Sturzenegger","year":"2004","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2014.04.020_bib0040","doi-asserted-by":"crossref","first-page":"955","DOI":"10.5664\/jcsm.3004","article-title":"Disrupted nighttime sleep in narcolepsy","volume":"9","author":"Roth","year":"2013","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0045","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1093\/sleep\/33.5.689","article-title":"Restless legs syndrome is frequent in narcolepsy with cataplexy patients","volume":"33","author":"Plazzi","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0050","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1389-9457(99)00007-6","article-title":"Clinical and polysomnographic features in DQB1*0602 positive and negative narcolepsy patients: results from the modafinil clinical trial","volume":"1","author":"Hong","year":"2000","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0055","first-page":"1409","article-title":"Searching for a marker of REM sleep behavior disorder: submentalis muscle EMG amplitude analysis during sleep in patients with narcolepsy\/cataplexy","volume":"31","author":"Ferri","year":"2008","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0060","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1093\/sleep\/29.12.1587","article-title":"Different periodicity and time structure of leg movements during sleep in narcolepsy\/cataplexy and restless legs syndrome","volume":"29","author":"Ferri","year":"2006","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0065","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.sleep.2009.08.003","article-title":"Sodium oxybate is an effective and safe treatment for narcolepsy","volume":"11","author":"Lammers","year":"2010","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0070","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.sleep.2003.11.002","article-title":"Sodium oxybate demonstrates long-term efficacy for the treatment of cataplexy in patients with narcolepsy","volume":"5","year":"2004","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0075","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.sleep.2005.03.010","article-title":"Further evidence supporting the use of sodium oxybate for the treatment of cataplexy: a double-blind, placebo-controlled study in 228 patients","volume":"6","year":"2005","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0080","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.smrv.2011.09.001","article-title":"Narcolepsy and effectiveness of gamma-hydroxybutyrate (GHB): a systematic review and meta-analysis of randomized controlled trials","volume":"16","author":"Boscolo-Berto","year":"2012","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2014.04.020_bib0085","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1093\/sleep\/27.7.1327","article-title":"A pilot study on the effects of sodium oxybate on sleep architecture and daytime alertness in narcolepsy","volume":"27","author":"Mamelak","year":"2004","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0090","doi-asserted-by":"crossref","first-page":"596","DOI":"10.5664\/jcsm.27994","article-title":"The nightly use of sodium oxybate is associated with a reduction in nocturnal sleep disruption: a double-blind, placebo-controlled study in patients with narcolepsy","volume":"6","author":"Black","year":"2010","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0095","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s11325-011-0520-2","article-title":"Catathrenia under sodium oxybate in narcolepsy with cataplexy","volume":"16","author":"Poli","year":"2012","journal-title":"Sleep Breath"},{"key":"10.1016\/j.sleep.2014.04.020_bib0100","doi-asserted-by":"crossref","first-page":"310","DOI":"10.5664\/JCSM.1082","article-title":"Sodium oxybate-induced sleep driving and sleep-related eating disorder","volume":"7","author":"Wallace","year":"2011","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0105","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.sleep.2006.06.003","article-title":"Restless legs syndrome in narcolepsy: a side effect of sodium oxybate?","volume":"8","author":"Abril","year":"2007","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0110","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1093\/sleep\/29.9.1189","article-title":"A randomized trial evaluating the effectiveness of sodium oxybate therapy on quality of life in narcolepsy","volume":"29","author":"Weaver","year":"2006","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0115","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s100720300004","article-title":"Italian version of the Epworth sleepiness scale: external validity","volume":"23","author":"Vignatelli","year":"2003","journal-title":"Neurol Sci"},{"key":"10.1016\/j.sleep.2014.04.020_bib0120","series-title":"A manual of standardized terminology, techniques, and scoring system for sleep stages of human subjects","year":"1968"},{"key":"10.1016\/j.sleep.2014.04.020_bib0125","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.sleep.2004.06.010","article-title":"Topographic mapping of the spectral components of the cyclic alternating pattern (CAP)","volume":"6","author":"Ferri","year":"2005","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0130","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S1389-9457(01)00149-6","article-title":"Atlas, rules, and recording techniques for the scoring of cyclic alternating pattern (CAP) in human sleep","volume":"2","author":"Terzano","year":"2001","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0135","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.clinph.2004.09.021","article-title":"Inter-rater reliability of sleep cyclic alternating pattern (CAP) scoring and validation of a new computer-assisted CAP scoring method","volume":"116","author":"Ferri","year":"2005","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.sleep.2014.04.020_bib0140","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.sleep.2006.01.001","volume":"7","author":"Zucconi","year":"2006","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0145","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1093\/sleep\/29.12.1587","article-title":"New approaches to the study of periodic leg movements during sleep in restless legs syndrome","volume":"29","author":"Ferri","year":"2006","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0150","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-2869.2008.00631.x","article-title":"A quantitative statistical analysis of the submentalis muscle EMG amplitude during sleep in normal controls and patients with REM sleep behavior disorder","volume":"17","author":"Ferri","year":"2008","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2014.04.020_bib0155","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.sleep.2010.06.003","article-title":"Improved computation of the atonia index in normal controls and patients with REM sleep behavior disorder","volume":"11","author":"Ferri","year":"2010","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0160","doi-asserted-by":"crossref","first-page":"451","DOI":"10.5664\/jcsm.2048","article-title":"Sodium oxybate for narcolepsy with cataplexy: systematic review and meta-analysis","volume":"8","author":"Alshaikh","year":"2012","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0165","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1093\/sleep\/29.7.939","article-title":"Sodium oxybate improves excessive daytime sleepiness in narcolepsy","volume":"29","author":"Black","year":"2006","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/WNF.0b013e318203d415","article-title":"Long-term follow-up of patients with narcolepsy\u2013cataplexy treated with sodium oxybate (Xyrem)","volume":"34","author":"Alshaikh","year":"2011","journal-title":"Clin Neuropharmacol"},{"key":"10.1016\/j.sleep.2014.04.020_bib0175","first-page":"42","article-title":"A randomized, double blind, placebo-controlled multicenter trial comparing the effects of three doses of orally administered sodium oxybate with placebo for the treatment of narcolepsy","volume":"25","year":"2002","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0180","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.sleep.2010.07.001","article-title":"Injurious REM sleep behaviour disorder in narcolepsy with cataplexy contributing to criminal proceedings and divorce","volume":"11","author":"Ingravallo","year":"2010","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0185","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.sleep.2012.09.009","article-title":"An observational clinical and video-polysomnographic study of the effects of clonazepam in REM sleep behavior disorder","volume":"14","author":"Ferri","year":"2013","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0190","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.sleep.2013.01.007","article-title":"Effects of long-term use of clonazepam on nonrapid eye movement sleep patterns in rapid eye movement sleep behavior disorder","volume":"14","author":"Ferri","year":"2013","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0195","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1093\/sleep\/9.1.232","article-title":"Comparative polysomnographic study of narcolepsy and idiopathic central nervous system hypersomnia","volume":"9","author":"Baker","year":"1986","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0200","first-page":"23","article-title":"Effects of nocturnal gamma-hydroxybutyrate on sleep\/waking patterns in narcolepsy\u2013cataplexy","volume":"7","author":"Broughton","year":"1980","journal-title":"Can J Neurol Sci"},{"key":"10.1016\/j.sleep.2014.04.020_bib0205","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1093\/sleep\/16.3.216","article-title":"Gammahydroxybutyrate and narcolepsy: a double-blind placebo-controlled study","volume":"16","author":"Lammers","year":"1993","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2014.04.020_bib0210","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.sleep.2009.05.004","article-title":"The nightly administration of sodium oxybate results in significant reduction in the nocturnal sleep disruption of patients with narcolepsy","volume":"10","author":"Black","year":"2009","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0215","doi-asserted-by":"crossref","first-page":"2675","DOI":"10.1016\/j.clinph.2005.08.004","article-title":"NREM sleep alterations in narcolepsy\/cataplexy","volume":"116","author":"Ferri","year":"2005","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.sleep.2014.04.020_bib0220","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.sleep.2005.12.003","article-title":"Cyclic alternating pattern (CAP) alterations in narcolepsy","volume":"7","author":"Terzano","year":"2006","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0225","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1016\/j.clinph.2011.02.028","article-title":"Cyclic alternating pattern in narcolepsy patients and healthy controls after partial and total sleep deprivation","volume":"122","author":"Poryazova","year":"2011","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.sleep.2014.04.020_bib0230","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.neulet.2007.12.025","article-title":"The slow-wave components of the Cyclic Alternating Pattern (CAP) have a role in sleep-related learning processes","volume":"432","author":"Ferri","year":"2008","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.sleep.2014.04.020_bib0235","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.sleep.2010.02.009","article-title":"Effects of NREM sleep instability on cognitive processing","volume":"11","author":"Aric\u00f2","year":"2010","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0240","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.sleep.2010.01.006","article-title":"The effects of experimental sleep fragmentation on cognitive processing","volume":"11","author":"Ferri","year":"2010","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2014.04.020_bib0245","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.pbb.2004.09.022","article-title":"Adolescent gamma-hydroxybutyric acid exposure decreases cortical N-methyl-d-aspartate receptor and impairs spatial learning","volume":"79","author":"Sircar","year":"2004","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.sleep.2014.04.020_bib0250","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.pbb.2007.12.007","article-title":"Effects of gamma-hydroxybutyrate (GHB) and its metabolic precursors on delayed-matching-to-position performance in rats","volume":"89","author":"Kueh","year":"2008","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.sleep.2014.04.020_bib0255","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1196\/annals.1432.044","article-title":"Gamma-hydroxybutyric acid-induced cognitive deficits in the female adolescent rat","volume":"1139","author":"Sircar","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.sleep.2014.04.020_bib0260","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1017\/S1461145709000157","article-title":"Neurotoxic effects induced by gammahydroxybutyric acid (GHB) in male rats","volume":"12","author":"Pedraza","year":"2009","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.sleep.2014.04.020_bib0265","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s11011-009-9136-7","article-title":"Effects of 1,4-butanediol administration on oxidative stress in rat brain: study of the neurotoxicity of gamma-hydroxybutyric acid in vivo","volume":"24","author":"Sgaravatti","year":"2009","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.sleep.2014.04.020_bib0270","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1365-2869.2007.00601.x","article-title":"Periodic leg movements during sleep and wakefulness in narcolepsy","volume":"16","author":"Dauvilliers","year":"2007","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2014.04.020_bib0275","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1365-2869.2011.00942.x","article-title":"Periodic leg movements during sleep in narcoleptic patients with or without restless legs syndrome","volume":"21","author":"Plazzi","year":"2012","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2014.04.020_bib0280","first-page":"1229","article-title":"Defining the boundaries of the response of sleep leg movements to a single dose of dopamine agonist","volume":"31","author":"Manconi","year":"2008","journal-title":"Sleep"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138994571400238X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138994571400238X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,20]],"date-time":"2020-08-20T15:09:20Z","timestamp":1597936160000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S138994571400238X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":55,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S138994571400238X"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2014.04.020","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of acute administration of sodium oxybate on nocturnal sleep polysomnography and on multiple sleep latency test in narcolepsy with cataplexy","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2014.04.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}