{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:40:07Z","timestamp":1791384007900,"version":"4.3.3"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","sleep-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.sleep.2017.03.029","type":"journal-article","created":{"date-parts":[[2017,5,19]],"date-time":"2017-05-19T10:00:28Z","timestamp":1495188028000},"page":"23-28","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"special_numbering":"C","title":["Morbidity and mortality of middle-aged and elderly narcoleptics"],"prefix":"10.1016","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6986-5254","authenticated-orcid":false,"given":"Poul","family":"Jennum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva Wiberg","family":"Thorstensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Line","family":"Pickering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikke","family":"Ibsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Kjellberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2017.03.029_bib1","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/S1474-4422(14)70075-4","article-title":"Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination","volume":"13","author":"Partinen","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.sleep.2017.03.029_bib2","doi-asserted-by":"crossref","first-page":"e0122478","DOI":"10.1371\/journal.pone.0122478","article-title":"Health-related stigma as a determinant of functioning in young adults with narcolepsy","volume":"10","author":"Kapella","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.sleep.2017.03.029_bib3","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.sleep.2013.03.002","article-title":"Narcolepsy is complicated by high medical and psychiatric comorbidities: a comparison with the general population","volume":"14","author":"Ohayon","year":"2013","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib4","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.sleep.2012.06.006","article-title":"Health, social, and economic consequences of narcolepsy: a controlled national study evaluating the societal effect on patients and their partners","volume":"13","author":"Jennum","year":"2012","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib5","doi-asserted-by":"crossref","first-page":"240","DOI":"10.5664\/jcsm.27493","article-title":"The economic consequences of narcolepsy","volume":"5","author":"Jennum","year":"2009","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1080\/17518420802011493","article-title":"Psychosocial and intellectual functioning in childhood narcolepsy","volume":"11","author":"Dorris","year":"2008","journal-title":"Dev Neurorehabil"},{"key":"10.1016\/j.sleep.2017.03.029_bib7","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1528-1157.1984.tb03438.x","article-title":"Comparison of the psychosocial effects of epilepsy and narcolepsy\/cataplexy: a controlled study","volume":"25","author":"Broughton","year":"1984","journal-title":"Epilepsia"},{"key":"10.1016\/j.sleep.2017.03.029_bib8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s11910-015-0546-0","article-title":"Sleep disorders in multiple sclerosis","volume":"15","author":"Veauthier","year":"2015","journal-title":"Rev Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.sleep.2017.03.029_bib9","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.sleep.2011.07.014","article-title":"Quality of life in patients with narcolepsy with cataplexy, narcolepsy without cataplexy, and idiopathic hypersomnia without long sleep time: comparison between patients on psychostimulants, drug-naive patients and the general Japanese population","volume":"13","author":"Ozaki","year":"2012","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib10","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.sleep.2006.10.010","article-title":"Health-related quality of life in patients with narcolepsy","volume":"8","author":"Dodel","year":"2007","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib11","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1111\/j.1528-1167.2010.02946.x","article-title":"The social and economic consequences of epilepsy: a controlled national study","volume":"52","author":"Jennum","year":"2011","journal-title":"Epilepsia"},{"key":"10.1016\/j.sleep.2017.03.029_bib12","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1177\/1403494810387965","article-title":"The Danish Civil registration system","volume":"39","author":"Pedersen","year":"2011","journal-title":"Scand J Public Health"},{"key":"10.1016\/j.sleep.2017.03.029_bib13","doi-asserted-by":"crossref","first-page":"89","DOI":"10.5664\/jcsm.3370","article-title":"The impact of gender on timeliness of narcolepsy diagnosis","volume":"10","author":"Won","year":"2014","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib14","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1093\/sleep\/25.2.197","article-title":"The epidemiology of narcolepsy in Olmsted County, Minnesota: a population-based study","volume":"25","author":"Silber","year":"2002","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.03.029_bib15","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/S1474-4422(14)70168-1","article-title":"Does autoreactivity have a role in narcolepsy?","volume":"13","author":"Partinen","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.sleep.2017.03.029_bib16","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.euroneuro.2011.05.001","article-title":"The socioeconomic consequences of multiple sclerosis: a controlled national study","volume":"22","author":"Jennum","year":"2012","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.sleep.2017.03.029_bib17","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/jsr.12044","article-title":"Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study","volume":"22","author":"Luca","year":"2013","journal-title":"J\u00a0Sleep Res"},{"key":"10.1016\/j.sleep.2017.03.029_bib18","doi-asserted-by":"crossref","first-page":"175","DOI":"10.5665\/sleep.2366","article-title":"High prevalence of precocious puberty and obesity in childhood narcolepsy with cataplexy","volume":"36","author":"Poli","year":"2013","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.03.029_bib19","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/sleep\/33.11.1457","article-title":"Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children","volume":"33","author":"Aran","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.03.029_bib20","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.sleep.2013.09.018","article-title":"Narcolepsy-cataplexy and schizophrenia in adolescents","volume":"15","author":"Huang","year":"2014","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib21","first-page":"30","article-title":"Narcolepsy presenting as schizophrenia: a literature review and two case reports","volume":"8","author":"Talih","year":"2011","journal-title":"Innov Clin Neurosci"},{"key":"10.1016\/j.sleep.2017.03.029_bib22","doi-asserted-by":"crossref","first-page":"335","DOI":"10.31887\/DCNS.2005.7.4\/jhabarubio","article-title":"Psychiatric aspects of organic sleep disorders","volume":"7","author":"Haba-Rubio","year":"2005","journal-title":"Dialogues Clin Neurosci"},{"key":"10.1016\/j.sleep.2017.03.029_bib23","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0165-1781(00)00227-4","article-title":"Prevalence of hallucinations and their pathological associations in the general population","volume":"97","author":"Ohayon","year":"2000","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.sleep.2017.03.029_bib24","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/00005053-199501000-00009","article-title":"Psychiatric morbidity in narcoleptics on chronic high dose methylphenidate therapy","volume":"183","author":"Pawluk","year":"1995","journal-title":"J\u00a0Nerv Ment Dis"},{"key":"10.1016\/j.sleep.2017.03.029_bib25","doi-asserted-by":"crossref","first-page":"615","DOI":"10.5665\/sleep.4582","article-title":"Psychiatric comorbidity and cognitive profile in children with narcolepsy with or without association to the H1N1 influenza vaccination","volume":"38","author":"Szakacs","year":"2015","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.03.029_bib26","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.sleep.2014.07.025","article-title":"Subjective deficits of attention, cognition and depression in patients with narcolepsy","volume":"16","author":"Zamarian","year":"2015","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.03.029_bib27","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1136\/jnnp.2008.161588","article-title":"Psychological health in central hypersomnias: the French Harmony study","volume":"80","author":"Dauvilliers","year":"2009","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"1","key":"10.1016\/j.sleep.2017.03.029_bib28","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3233\/JPD-150725","article-title":"Risk factor profile in Parkinson's disease subtype with REM sleep behavior disorder","volume":"6","author":"Jacobs","year":"2016","journal-title":"J Parkinsons Dis"},{"key":"10.1016\/j.sleep.2017.03.029_bib29","article-title":"Cerebrospinal fluid biomarkers of neurodegeneration are decreased or normal in narcolepsy","author":"Jennum","year":"2016","journal-title":"Sleep"},{"issue":"3","key":"10.1016\/j.sleep.2017.03.029_bib30","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1111\/jsr.12374","article-title":"The European narcolepsy network (EU-NN) database","volume":"25","author":"Khatami","year":"2016","journal-title":"J\u00a0Sleep Res"},{"key":"10.1016\/j.sleep.2017.03.029_bib31","doi-asserted-by":"crossref","first-page":"91","DOI":"10.5665\/sleep.2308","article-title":"Attenuated heart rate response is associated with hypocretin deficiency in patients with narcolepsy","volume":"36","author":"Sorensen","year":"2013","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.03.029_bib32","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.0889-7204.2004.02442.x","article-title":"Sleep-disordered breathing and the association with cardiovascular risk","volume":"19","author":"Merritt","year":"2004","journal-title":"Prog Cardiovasc Nurs"},{"key":"10.1016\/j.sleep.2017.03.029_bib33","doi-asserted-by":"crossref","first-page":"835","DOI":"10.5665\/sleep.2706","article-title":"Comorbidity and mortality of narcolepsy: a controlled retro- and prospective national study","volume":"36","author":"Jennum","year":"2013","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.03.029_bib34","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000348719","article-title":"Sleep-disordered breathing and periodic limb movements in narcolepsy with cataplexy: a systematic analysis of 35 consecutive patients","volume":"70","author":"Pizza","year":"2013","journal-title":"Eur Neurol"},{"key":"10.1016\/j.sleep.2017.03.029_bib35","first-page":"542","article-title":"Narcolepsy in adolescents","volume":"21","author":"Sullivan","year":"2010","journal-title":"Adolesc Med State Art Rev"},{"key":"10.1016\/j.sleep.2017.03.029_bib36","doi-asserted-by":"crossref","first-page":"439","DOI":"10.5665\/sleep.3470","article-title":"Increased mortality in narcolepsy","volume":"37","author":"Ohayon","year":"2014","journal-title":"Sleep"},{"issue":"7","key":"10.1016\/j.sleep.2017.03.029_bib37","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1111\/epi.13421","article-title":"Long-term socioeconomic consequences and health care costs of childhood and adolescent-onset epilepsy","volume":"57","author":"Jennum","year":"2016","journal-title":"Epilepsia"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945717301880?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945717301880?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T15:03:28Z","timestamp":1659020608000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945717301880"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":37,"alternative-id":["S1389945717301880"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2017.03.029","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Morbidity and mortality of middle-aged and elderly narcoleptics","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2017.03.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}