{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T15:34:11Z","timestamp":1774366451462,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","sleep-journal.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.sleep.2017.09.029","type":"journal-article","created":{"date-parts":[[2017,10,23]],"date-time":"2017-10-23T20:12:06Z","timestamp":1508789526000},"page":"68-72","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Does continuous positive airway pressure treatment affect autonomic nervous system in patients with severe obstructive sleep apnea?"],"prefix":"10.1016","volume":"42","author":[{"given":"Francesca","family":"Izzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Placidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Liguori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedetta","family":"Lauretti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Girolama A.","family":"Marfia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Pisani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola B.","family":"Mercuri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilla","family":"Rocchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.sleep.2017.09.029_bib1","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1212\/WNL.0000000000000605","article-title":"Neural control of the heart: recent concepts and clinical correlations","volume":"83","author":"Palma","year":"2014","journal-title":"Neurology"},{"issue":"12","key":"10.1016\/j.sleep.2017.09.029_bib2","doi-asserted-by":"crossref","first-page":"H1683","DOI":"10.1152\/ajpheart.00554.2013","article-title":"Central control of cardiovascular function during sleep","volume":"305","author":"Silvani","year":"2013","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.sleep.2017.09.029_bib3","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.smrv.2015.05.005","article-title":"Cardiovascular autonomic dysfunctions and sleep disorders","volume":"26","author":"Calandra-Buonaura","year":"2016","journal-title":"Sleep Med Rev"},{"issue":"9","key":"10.1016\/j.sleep.2017.09.029_bib4","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1164\/rccm.2109080","article-title":"Epidemiology of obstructive sleep apnea: a population health perspective","volume":"165","author":"Young","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2017.09.029_bib5","article-title":"Is high and fluctuating muscle nerve sympathetic activity in the sleep apnoea syndrome of pathogenetic importance for the development of hypertension?","volume":"6","author":"Hedner","year":"1988","journal-title":"J\u00a0Hypertens Suppl"},{"key":"10.1016\/j.sleep.2017.09.029_bib6","doi-asserted-by":"crossref","DOI":"10.1172\/JCI118235","article-title":"Sympathetic neural mechanisms in obstructive sleep apnea","volume":"96","author":"Somers","year":"1995","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.sleep.2017.09.029_bib7","doi-asserted-by":"crossref","DOI":"10.1111\/j.1475-097X.1996.tb00569.x","article-title":"Cardiac sympathovagal balance during sleep apnea episodes","volume":"16","author":"Vanninen","year":"1996","journal-title":"Clin Physiol"},{"issue":"1\u20132","key":"10.1016\/j.sleep.2017.09.029_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF01828839","article-title":"Cardiovascular autonomic dysfunction in normotensive awake subjects with obstructive sleep apnoea syndrome","volume":"4","author":"Cortelli","year":"1994","journal-title":"Clin Auton Res"},{"issue":"11","key":"10.1016\/j.sleep.2017.09.029_bib9","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1002\/mds.20153","article-title":"Assessment of autonomic dysfunction in Parkinson's disease: the SCOPA-AUT","volume":"19","author":"Visser","year":"2004","journal-title":"Mov Disord"},{"key":"10.1016\/j.sleep.2017.09.029_bib10","doi-asserted-by":"crossref","first-page":"597","DOI":"10.5664\/jcsm.2172","article-title":"Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. Deliberations of the sleep apnea definitions task force of the American academy of sleep medicine","volume":"8","author":"Berry","year":"2012","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"6","key":"10.1016\/j.sleep.2017.09.029_bib11","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A\u00a0new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.sleep.2017.09.029_bib12","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s100720300004","article-title":"GINSEN (Gruppo Italiano Narcolessia Studio Epidemiologico Nazionale. Italian version of the Epworth sleepiness scale: external validity","volume":"23","author":"Vignatelli","year":"2003","journal-title":"Neurol Sci"},{"key":"10.1016\/j.sleep.2017.09.029_bib13","series-title":"Autonomic failure: a text book of clinical disorders of the autonomic nervous system","first-page":"169","article-title":"Investigation of autonomic disorders","author":"Mathias","year":"1999"},{"issue":"2","key":"10.1016\/j.sleep.2017.09.029_bib14","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.cmpb.2014.08.002","article-title":"A\u00a0new integrated instrumental approach to autonomic nervous system assessment","volume":"117","author":"Corazza","year":"2014","journal-title":"Comput Methods Programs Biomed"},{"issue":"5","key":"10.1016\/j.sleep.2017.09.029_bib15","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1053\/smrv.2002.0273","article-title":"Sleep disordered breathing and nocturnal polyuria: nocturia and enuresis","volume":"7","author":"Umlauf","year":"2003","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2017.09.029_bib16","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/B978-0-444-63274-6.00014-X","article-title":"Affective brain areas and sleep-disordered breathing","volume":"209","author":"Harper","year":"2014","journal-title":"Prog Brain Res"},{"issue":"1","key":"10.1016\/j.sleep.2017.09.029_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1113\/jphysiol.1994.sp019997","article-title":"Annual review prize lecture. Central nervous mechanisms contributing to cardiovascular control","volume":"474","author":"Spyer","year":"1994","journal-title":"J\u00a0Physiol"},{"issue":"4\u20135","key":"10.1016\/j.sleep.2017.09.029_bib18","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1023\/A:1025080314925","article-title":"Functional organization of brain pathways subserving the baroreceptor reflex: studies in conscious animals using immediate early gene expression","volume":"23","author":"Dampney","year":"2003","journal-title":"Cell Mol Neurobiol"},{"issue":"12","key":"10.1016\/j.sleep.2017.09.029_bib19","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/j.sleep.2013.08.781","article-title":"Autonomic complaints in patients with restless legs syndrome","volume":"14","author":"Shneyder","year":"2013","journal-title":"Sleep Med"},{"issue":"6","key":"10.1016\/j.sleep.2017.09.029_bib20","first-page":"1112","article-title":"Autonomic symptoms in idiopathic REM behavior disorder: a multicentre case-control study","volume":"261","author":"Ferini-Strambi","year":"2014","journal-title":"J\u00a0Neurol"},{"issue":"5","key":"10.1016\/j.sleep.2017.09.029_bib21","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s00395-005-0536-5","article-title":"Influence of obstructive sleep apnea on heart rate turbulence","volume":"100","author":"Yang","year":"2005","journal-title":"Basic Res Cardiol"},{"issue":"7","key":"10.1016\/j.sleep.2017.09.029_bib22","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.ejim.2013.03.011","article-title":"One night on-call: sleep deprivation affects cardiac autonomic control and inflammation in physicians","volume":"24","author":"Tobaldini","year":"2013","journal-title":"Eur J Intern Med"},{"issue":"3","key":"10.1016\/j.sleep.2017.09.029_bib23","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1365-2869.2008.00659.x","article-title":"Daytime sleepiness and neural cardiac modulation in sleep-related breathing disorders","volume":"17","author":"Lombardi","year":"2008","journal-title":"J\u00a0Sleep Res"},{"issue":"2","key":"10.1016\/j.sleep.2017.09.029_bib24","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.sleep.2014.10.011","article-title":"Bidirectional interactions between the baroreceptor reflex and arousal: an update","volume":"16","author":"Silvani","year":"2015","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.sleep.2017.09.029_bib25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.5665\/sleep.1582","article-title":"Magnetic resonance spectroscopy and neurocognitive dysfunction in obstructive sleep apnea before and after CPAP treatment","volume":"35","author":"O'Donoghue","year":"2012","journal-title":"Sleep"},{"issue":"10","key":"10.1016\/j.sleep.2017.09.029_bib26","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1056\/NEJMoa1606599","article-title":"CPAP for prevention of cardiovascular events in obstructive sleep apnea","volume":"375","author":"McEvoy","year":"2016","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.sleep.2017.09.029_bib27","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1001\/archinte.167.8.757","article-title":"The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials","volume":"167","author":"Haentjens","year":"2007","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.sleep.2017.09.029_bib28","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1161\/HYPERTENSIONAHA.106.085175","article-title":"Effect of nocturnal nasal continuous positive airway pressure on blood pressure in obstructive sleep apnea","volume":"50","author":"Bazzano","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.sleep.2017.09.029_bib29","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1164\/rccm.200901-0050OC","article-title":"Long-term effect of continuous positive airway pressure in hypertensive patients with sleep apnea","volume":"181","author":"Barb\u00e9","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2017.09.029_bib30","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1378\/chest.95.4.735","article-title":"Heart rate response to breath-hold, Valsalva and Mueller maneuvers in obstructive sleep apnea","volume":"95","author":"Hanly","year":"1989","journal-title":"Chest"},{"key":"10.1016\/j.sleep.2017.09.029_bib31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF01826208","article-title":"Autonomic nervous system function in patients with primary obstructive sleep apnoea syndrome","volume":"1","author":"Svanborg","year":"1991","journal-title":"Clin Auton Res"},{"issue":"2","key":"10.1016\/j.sleep.2017.09.029_bib32","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/ana.410070209","article-title":"Cold face test in the assessment of trigeminal-brainstem-vagal function in humans","volume":"7","author":"Khurana","year":"1980","journal-title":"Ann Neurol"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945717304033?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945717304033?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T09:05:37Z","timestamp":1603184737000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945717304033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":32,"alternative-id":["S1389945717304033"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2017.09.029","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Does continuous positive airway pressure treatment affect autonomic nervous system in patients with severe obstructive sleep apnea?","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2017.09.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}