{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T06:36:17Z","timestamp":1789799777329,"version":"4.0.1"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81271494"],"award-info":[{"award-number":["81271494"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81301138"],"award-info":[{"award-number":["81301138"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81030028"],"award-info":[{"award-number":["81030028"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31500867"],"award-info":[{"award-number":["31500867"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81225012"],"award-info":[{"award-number":["81225012"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","sleep-journal.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.sleep.2017.12.016","type":"journal-article","created":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T13:57:10Z","timestamp":1519739830000},"page":"132-139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"special_numbering":"C","title":["Mapping the changed hubs and corresponding functional connectivity in idiopathic restless legs syndrome"],"prefix":"10.1016","volume":"45","author":[{"given":"Chunyan","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaojian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqin","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6482-9710","authenticated-orcid":false,"given":"Yuping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2017.12.016_bib1","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1389-9457(03)00010-8","article-title":"Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the national institutes of health","volume":"4","author":"Allen","year":"2003","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib2","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S1474-4422(05)70139-3","article-title":"The restless legs syndrome","volume":"4","author":"Trenkwalder","year":"2005","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.sleep.2017.12.016_bib3","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/ana.410410513","article-title":"Cerebral generators involved in the pathogenesis of the restless legs syndrome","volume":"41","author":"Bucher","year":"1997","journal-title":"Ann Neurol"},{"key":"10.1016\/j.sleep.2017.12.016_bib4","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3174\/ajnr.A2829","article-title":"Investigation of unmedicated early onset restless legs syndrome by voxel-based morphometry, T2 relaxometry, and functional MR imaging during the night-time hours","volume":"33","author":"Margariti","year":"2012","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.sleep.2017.12.016_bib5","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.sleep.2007.03.021","article-title":"Cerebral correlates of muscle tone fluctuations in restless legs syndrome: a pilot study with combined functional magnetic resonance imaging and anterior tibial muscle electromyography","volume":"9","author":"Spiegelhalder","year":"2008","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib6","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.sleep.2014.12.029","article-title":"Mapping intrinsic functional brain changes and repetitive transcranial magnetic stimulation neuromodulation in idiopathic restless legs syndrome: a resting-state functional magnetic resonance imaging study","volume":"16","author":"Liu","year":"2015","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib7","doi-asserted-by":"crossref","first-page":"10046","DOI":"10.1073\/pnas.0604187103","article-title":"Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems","volume":"103","author":"Fox","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sleep.2017.12.016_bib8","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1523\/JNEUROSCI.5062-08.2009","article-title":"Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease","volume":"29","author":"Buckner","year":"2009","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.sleep.2017.12.016_bib9","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.neuron.2011.09.006","article-title":"Functional network organization of the human brain","volume":"72","author":"Power","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.sleep.2017.12.016_bib10","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1152\/jn.00338.2011","article-title":"The organization of the human cerebral cortex estimated by intrinsic functional connectivity","volume":"106","author":"Yeo","year":"2011","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.sleep.2017.12.016_bib11","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/j.neuroimage.2012.07.045","article-title":"Tractography-based parcellation of the human left inferior parietal lobule","volume":"63","author":"Wang","year":"2012","journal-title":"Neuroimage"},{"key":"10.1016\/j.sleep.2017.12.016_bib12","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1002\/hbm.22745","article-title":"Determination of the posterior boundary of Wernicke's area based on multimodal connectivity profiles","volume":"36","author":"Wang","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.sleep.2017.12.016_bib13","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/hbm.22626","article-title":"Convergent functional architecture of the superior parietal lobule unraveled with multimodal neuroimaging approaches","volume":"36","author":"Wang","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.sleep.2017.12.016_bib14","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.neuron.2014.05.014","article-title":"Intrinsic and task-evoked network architectures of the human brain","volume":"83","author":"Cole","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.sleep.2017.12.016_bib15","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1007\/s11682-015-9460-y","article-title":"A\u00a0lateralized top-down network for visuospatial attention and neglect","volume":"10","author":"Wang","year":"2016","journal-title":"Brain Imag Behav"},{"key":"10.1016\/j.sleep.2017.12.016_bib16","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1002\/jnr.23705","article-title":"Network science and the human brain: using graph theory to understand the brain and one of its hubs, the amygdala, in health and disease","volume":"94","author":"Mears","year":"2016","journal-title":"J\u00a0Neurosci Res"},{"key":"10.1016\/j.sleep.2017.12.016_bib17","doi-asserted-by":"crossref","first-page":"e159","DOI":"10.1371\/journal.pbio.0060159","article-title":"Mapping the structural core of human cerebral cortex","volume":"6","author":"Hagmann","year":"2008","journal-title":"PLoS Biol"},{"key":"10.1016\/j.sleep.2017.12.016_bib18","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/nrn2575","article-title":"Complex brain networks: graph theoretical analysis of structural and functional systems","volume":"10","author":"Bullmore","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.sleep.2017.12.016_bib19","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1177\/1073858406293182","article-title":"Small-world brain networks","volume":"12","author":"Bassett","year":"2006","journal-title":"Neuroscientist"},{"key":"10.1016\/j.sleep.2017.12.016_bib20","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.tics.2013.09.012","article-title":"Network hubs in the human brain","volume":"17","author":"van den Heuvel","year":"2013","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.sleep.2017.12.016_bib21","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.1016\/j.neuroimage.2009.11.001","article-title":"Identifying the brain's most globally connected regions","volume":"49","author":"Cole","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.sleep.2017.12.016_bib22","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1002\/hbm.22241","article-title":"Overlapping and segregated resting-state functional connectivity in patients with major depressive disorder with and without childhood neglect","volume":"35","author":"Wang","year":"2014","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.sleep.2017.12.016_bib23","doi-asserted-by":"crossref","first-page":"120","DOI":"10.3389\/fnana.2016.00120","article-title":"Changed hub and corresponding functional connectivity of subgenual anterior cingulate cortex in major depressive disorder","volume":"10","author":"Wu","year":"2016","journal-title":"Front Neuroanat"},{"key":"10.1016\/j.sleep.2017.12.016_bib24","doi-asserted-by":"crossref","DOI":"10.1093\/scan\/nsx100","article-title":"Electroconvulsive therapy selectively enhanced feedforward connectivity from fusiform face area to amygdala in major depressive disorder","author":"Wang","year":"2017","journal-title":"Soc Cogn Affect Neurosci"},{"key":"10.1016\/j.sleep.2017.12.016_bib25","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.jad.2017.09.001","article-title":"Local functional connectivity density is closely associated with the response of electroconvulsive therapy in major depressive disorder","volume":"225","author":"Wang","year":"2017","journal-title":"J\u00a0Affect Disord"},{"key":"10.1016\/j.sleep.2017.12.016_bib26","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1093\/cercor\/bhr269","article-title":"Network centrality in the human functional connectome","volume":"22","author":"Zuo","year":"2012","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.sleep.2017.12.016_bib27","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/nrn3901","article-title":"The connectomics of brain disorders","volume":"16","author":"Fornito","year":"2015","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.sleep.2017.12.016_bib28","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1002\/mds.25576","article-title":"Low brain iron content in idiopathic restless legs syndrome patients detected by phase imaging","volume":"28","author":"Rizzo","year":"2013","journal-title":"Mov Disord"},{"key":"10.1016\/j.sleep.2017.12.016_bib29","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1212\/WNL.0000000000001455","article-title":"Quantitative susceptibility mapping suggests a paramagnetic effect in PML","volume":"84","author":"Carra-Dalliere","year":"2015","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2017.12.016_bib30","doi-asserted-by":"crossref","first-page":"3712","DOI":"10.1093\/brain\/aws266","article-title":"Abnormal medial thalamic metabolism in patients with idiopathic restless legs syndrome","volume":"135","author":"Rizzo","year":"2012","journal-title":"Brain"},{"key":"10.1016\/j.sleep.2017.12.016_bib31","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.sleep.2013.09.030","article-title":"Functional connectivity alternation of the thalamus in restless legs syndrome patients during the asymptomatic period: a resting-state connectivity study using functional magnetic resonance imaging","volume":"15","author":"Ku","year":"2014","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib32","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1093\/brain\/awl163","article-title":"Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding","volume":"129","author":"Cervenka","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.sleep.2017.12.016_bib33","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1093\/brain\/awg033","article-title":"Pharmacologically modulated fMRI\u2500cortical responsiveness to levodopa in drug-naive hemiparkinsonian patients","volume":"126","author":"Buhmann","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.sleep.2017.12.016_bib34","first-page":"450","article-title":"Effects of motor cortex modulation and descending inhibitory systems on pain thresholds in healthy subjects","volume":"13","author":"Reidler","year":"2012","journal-title":"J\u00a0Pain"},{"key":"10.1016\/j.sleep.2017.12.016_bib35","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.pain.2006.02.023","article-title":"A\u00a0sham-controlled, phase II trial of transcranial direct current stimulation for the treatment of central pain in traumatic spinal cord injury","volume":"122","author":"Fregni","year":"2006","journal-title":"Pain"},{"key":"10.1016\/j.sleep.2017.12.016_bib36","first-page":"610","article-title":"Transcranial DC stimulation in fibromyalgia: optimized cortical target supported by high-resolution computational models","volume":"12","author":"Mendonca","year":"2011","journal-title":"J\u00a0Pain"},{"key":"10.1016\/j.sleep.2017.12.016_bib37","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.brs.2008.09.009","article-title":"A\u00a0preliminary study of transcranial direct current stimulation for the treatment of refractory chronic pelvic pain","volume":"2","author":"Fenton","year":"2009","journal-title":"Brain Stimul"},{"key":"10.1016\/j.sleep.2017.12.016_bib38","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1097\/00001756-200303240-00019","article-title":"Retrosplenial cortical activation in the fibromyalgia syndrome","volume":"14","author":"Wik","year":"2003","journal-title":"Neuroreport"},{"key":"10.1016\/j.sleep.2017.12.016_bib39","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/BF00237906","article-title":"A\u00a0method to discriminate axonal from cellbody activity and to analyse \u201csilent cells\u201d","volume":"21","author":"Fries","year":"1974","journal-title":"Exp Brain Res"},{"key":"10.1016\/j.sleep.2017.12.016_bib40","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.sleep.2016.07.018","article-title":"Brain imaging and networks in restless legs syndrome","volume":"31","author":"Rizzo","year":"2017","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib41","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1002\/ana.410410108","article-title":"Activation mapping in essential tremor with functional magnetic resonance imaging","volume":"41","author":"Bucher","year":"1997","journal-title":"Ann Neurol"},{"key":"10.1016\/j.sleep.2017.12.016_bib42","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1038\/nn1544","article-title":"The cerebellum communicates with the basal ganglia","volume":"8","author":"Hoshi","year":"2005","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.sleep.2017.12.016_bib43","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/BF01244940","article-title":"Dopamine D2 receptor alteration in patients with periodic movements in sleep (nocturnal myoclonus)","volume":"93","author":"Staedt","year":"1993","journal-title":"J\u00a0Neural Transm Gen Sect"},{"key":"10.1016\/j.sleep.2017.12.016_bib44","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.sleep.2013.05.017","article-title":"Sensory symptoms in restless legs syndrome: the enigma of pain","volume":"14","author":"Winkelman","year":"2013","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib45","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1073\/pnas.98.2.676","article-title":"A\u00a0default mode of brain function","volume":"98","author":"Raichle","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sleep.2017.12.016_bib46","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1002\/hbm.23488","article-title":"Correspondent functional topography of the human left inferior parietal lobule at rest and under task revealed using resting-state fMRI and coactivation based parcellation","volume":"38","author":"Wang","year":"2017","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.sleep.2017.12.016_bib47","doi-asserted-by":"crossref","DOI":"10.1002\/hbm.23311","article-title":"Functional topography of the right inferior parietal lobule structured by anatomical connectivity profiles","author":"Wang","year":"2016","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.sleep.2017.12.016_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fnana.2016.00041","article-title":"Distinct changes in functional connectivity in posteromedial cortex subregions during the progress of Alzheimer's disease","volume":"10","author":"Wu","year":"2016","journal-title":"Front Neuroanat"},{"key":"10.1016\/j.sleep.2017.12.016_bib49","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.sleep.2016.05.007","article-title":"Default mode network disturbances in restless legs syndrome\/Willis-Ekbom disease","volume":"23","author":"Ku","year":"2016","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib50","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/brain\/awh441","article-title":"The role of opioids in restless legs syndrome: an [11C]diprenorphine PET study","volume":"128","author":"von Spiczak","year":"2005","journal-title":"Brain"},{"key":"10.1016\/j.sleep.2017.12.016_bib51","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1126\/science.288.5472.1769","article-title":"Psychological and neural mechanisms of the affective dimension of pain","volume":"288","author":"Price","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.sleep.2017.12.016_bib52","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.sleep.2011.01.021","article-title":"Sensations in restless legs syndrome","volume":"13","author":"Karroum","year":"2012","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2017.12.016_bib53","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1093\/gerona\/glp161","article-title":"Prevalence and clinical correlates of restless legs syndrome in an elderly French population: the SYNAPSE study","volume":"65","author":"Celle","year":"2010","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.sleep.2017.12.016_bib54","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1002\/mds.23353","article-title":"Short-term attention and verbal fluency is decreased in restless legs syndrome patients","volume":"25","author":"Fulda","year":"2010","journal-title":"Mov Disord"},{"key":"10.1016\/j.sleep.2017.12.016_bib55","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1093\/sleep\/32.5.589","article-title":"Review of the relationship of restless legs syndrome and periodic limb movements in sleep to hypertension, heart disease, and stroke","volume":"32","author":"Walters","year":"2009","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.12.016_bib56","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1053\/smrv.1999.0075","article-title":"Depression and insomnia: questions of cause and effect","volume":"4","author":"Lustberg","year":"2000","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2017.12.016_bib57","first-page":"891","article-title":"Restless legs syndrome, periodic limb movements in sleep, and depression","volume":"28","author":"Picchietti","year":"2005","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2017.12.016_bib58","first-page":"23","article-title":"A\u00a0magnetic resonance spectroscopy investigation of the anterior cingulate cortex and prefrontal cortex in chronic pain patients","volume":"28","author":"Fukui","year":"2008","journal-title":"Nihon Shinkei Seishin Yakurigaku Zasshi"},{"key":"10.1016\/j.sleep.2017.12.016_bib59","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3389\/fnins.2017.00259","article-title":"Aberrant functional connectivity architecture in participants with chronic insomnia disorder accompanying cognitive dysfunction: a whole-brain, data-driven analysis","volume":"11","author":"Pang","year":"2017","journal-title":"Front Neurosci"},{"key":"10.1016\/j.sleep.2017.12.016_bib60","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/j.neuroimage.2004.10.021","article-title":"Bilateral thalamic gray matter changes in patients with restless legs syndrome","volume":"24","author":"Etgen","year":"2005","journal-title":"Neuroimage"},{"key":"10.1016\/j.sleep.2017.12.016_bib61","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1016\/j.clinph.2004.01.031","article-title":"Why do restless legs occur at rest? Pathophysiology of neuronal structures in RLS. Neurophysiology of RLS (part 2)","volume":"115","author":"Trenkwalder","year":"2004","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.sleep.2017.12.016_bib62","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.jad.2017.08.084","article-title":"Selective functional dysconnectivity of the dorsal-anterior subregion of the precuneus in drug-naive major depressive disorder","volume":"225","author":"Zhu","year":"2018","journal-title":"J\u00a0Affect Disord"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945718300327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945718300327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,23]],"date-time":"2018-08-23T16:21:11Z","timestamp":1535041271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945718300327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":62,"alternative-id":["S1389945718300327"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2017.12.016","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mapping the changed hubs and corresponding functional connectivity in idiopathic restless legs syndrome","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2017.12.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}