{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:20:52Z","timestamp":1792790452306,"version":"4.5.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100009601","name":"Beijing Municipal Administration of Hospitals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.sleep.2019.12.024","type":"journal-article","created":{"date-parts":[[2020,1,11]],"date-time":"2020-01-11T02:17:57Z","timestamp":1578709077000},"page":"34-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["Different iron deposition patterns in hemodialysis patients with and without restless legs syndrome: a quantitative susceptibility mapping study"],"prefix":"10.1016","volume":"69","author":[{"given":"Hao","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-yan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zong-li","family":"Diao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"He-yu","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng-yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng-fei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng-han","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-hu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-chang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/00004691-200103000-00004","article-title":"Restless legs syndrome: a review of clinical and pathophysiologic features","volume":"18","author":"Allen","year":"2001","journal-title":"J\u00a0Clin Neurophysiol"},{"issue":"9","key":"10.1016\/j.sleep.2019.12.024_bib2","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.sleep.2010.07.007","article-title":"Restless legs syndrome: understanding its consequences and the need for better treatment","volume":"11","author":"Earley","year":"2010","journal-title":"Sleep Med"},{"issue":"9456","key":"10.1016\/j.sleep.2019.12.024_bib3","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0140-6736(05)17789-7","article-title":"Chronic kidney disease: the global challenge","volume":"365","author":"Meguid El Nahas","year":"2005","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib4","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S1389-9457(03)00010-8","article-title":"Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health","volume":"4","author":"Allen","year":"2003","journal-title":"Sleep Med"},{"issue":"13","key":"10.1016\/j.sleep.2019.12.024_bib5","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1002\/mds.25576","article-title":"Low brain iron content in idiopathic restless legs syndrome patients detected by phase imaging","volume":"28","author":"Rizzo","year":"2013","journal-title":"Mov Disord"},{"key":"10.1016\/j.sleep.2019.12.024_bib6","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.sleep.2016.05.001","article-title":"Brain iron deficiency in idiopathic restless legs syndrome measured by quantitative magnetic susceptibility at 7 tesla","volume":"22","author":"Li","year":"2016","journal-title":"Sleep Med"},{"issue":"11","key":"10.1016\/j.sleep.2019.12.024_bib7","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.sleep.2014.05.009","article-title":"Altered brain iron homeostasis and dopaminergic function in restless legs syndrome (Willis-Ekbom disease)","volume":"15","author":"Earley","year":"2014","journal-title":"Sleep Med"},{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib8","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1007\/s11011-014-9608-2","article-title":"Quantitative measurement of brain iron deposition in patients with haemodialysis using susceptibility mapping","volume":"30","author":"Chai","year":"2015","journal-title":"Metab Brain Dis"},{"issue":"3","key":"10.1016\/j.sleep.2019.12.024_bib9","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1002\/jmri.26226","article-title":"Increased iron deposition of deep cerebral gray matter structures in hemodialysis patients: a longitudinal study using quantitative susceptibility mapping","volume":"49","author":"Chai","year":"2019","journal-title":"J\u00a0Magn Reson Imaging"},{"key":"10.1016\/j.sleep.2019.12.024_bib10","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.parkreldis.2017.08.013","article-title":"Different iron deposition patterns in early- and middle-late-onset Parkinson's disease","volume":"44","author":"Xuan","year":"2017","journal-title":"Park Relat Disord"},{"issue":"7","key":"10.1016\/j.sleep.2019.12.024_bib11","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1021\/acschemneuro.8b00194","article-title":"Increased iron deposition on brain quantitative susceptibility mapping correlates with decreased cognitive function in alzheimer's disease","volume":"9","author":"Du","year":"2018","journal-title":"ACS Chem Neurosci"},{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib12","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1148\/radiol.2018180136","article-title":"Brain iron at quantitative MRI is associated with disability in multiple sclerosis","volume":"289","author":"Zivadinov","year":"2018","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.sleep.2019.12.024_bib13","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1002\/mrm.25358","article-title":"Quantitative susceptibility mapping (QSM): decoding MRI data for a tissue magnetic biomarker","volume":"73","author":"Wang","year":"2015","journal-title":"Magn Reson Med"},{"key":"10.1016\/j.sleep.2019.12.024_bib14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.neuroimage.2012.09.055","article-title":"Toward in\u00a0vivo histology: a comparison of quantitative susceptibility mapping (QSM) with magnitude-, phase-, and R2*-imaging at ultra-high magnetic field strength","volume":"65","author":"Deistung","year":"2013","journal-title":"Neuroimage"},{"issue":"6","key":"10.1016\/j.sleep.2019.12.024_bib15","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1002\/jmri.24951","article-title":"Subcortical gray matter segmentation and voxel-based analysis using transverse relaxation and quantitative susceptibility mapping with application to multiple sclerosis","volume":"42","author":"Cobzas","year":"2015","journal-title":"J\u00a0Magn Reson Imaging"},{"issue":"5","key":"10.1016\/j.sleep.2019.12.024_bib16","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.sleep.2005.11.009","article-title":"MRI-determined regional brain iron concentrations in early- and late-onset restless legs syndrome","volume":"7","author":"Earley","year":"2006","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2019.12.024_bib17","first-page":"341","article-title":"A\u00a0comparison of MRI tissue relaxometry and ROI methods used to determine regional brain iron concentrations in restless legs syndrome","volume":"8","author":"Moon","year":"2015","journal-title":"Med Dev"},{"issue":"3","key":"10.1016\/j.sleep.2019.12.024_bib18","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3988\/jcn.2014.10.3.197","article-title":"T2 relaxometry using 3.0-tesla magnetic resonance imaging of the brain in early- and late-onset restless legs syndrome","volume":"10","author":"Moon","year":"2014","journal-title":"J\u00a0Clin Neurol"},{"issue":"1","key":"10.1016\/j.sleep.2019.12.024_bib19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1600-0609.2012.01783.x","article-title":"Evidence for tissue iron overload in long-term hemodialysis patients and the impact of withdrawing parenteral iron","volume":"89","author":"Ghoti","year":"2012","journal-title":"Eur J Haematol"},{"issue":"4","key":"10.1016\/j.sleep.2019.12.024_bib20","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1007\/s11011-015-9664-2","article-title":"Increased brain iron deposition is a risk factor for brain atrophy in patients with haemodialysis: a combined study of quantitative susceptibility mapping and whole brain volume analysis","volume":"30","author":"Chai","year":"2015","journal-title":"Metab Brain Dis"},{"key":"10.1016\/j.sleep.2019.12.024_bib21","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.smrv.2019.03.006","article-title":"Neurochemical features of idiopathic restless legs syndrome","volume":"45","author":"Jimenez-Jimenez","year":"2019","journal-title":"Sleep Med Rev"},{"issue":"8","key":"10.1016\/j.sleep.2019.12.024_bib22","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.sleep.2014.03.025","article-title":"Restless legs syndrome\/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria-history, rationale, description, and significance","volume":"15","author":"Allen","year":"2014","journal-title":"Sleep Med"},{"issue":"4","key":"10.1016\/j.sleep.2019.12.024_bib23","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.neuroimage.2010.11.088","article-title":"Quantitative susceptibility mapping of human brain reflects spatial variation in tissue composition","volume":"55","author":"Li","year":"2011","journal-title":"Neuroimage"},{"issue":"6","key":"10.1016\/j.sleep.2019.12.024_bib24","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1002\/hbm.22360","article-title":"Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan","volume":"35","author":"Li","year":"2014","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.sleep.2019.12.024_bib25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.neuroimage.2014.12.043","article-title":"A\u00a0method for estimating and removing streaking artifacts in quantitative susceptibility mapping","volume":"108","author":"Li","year":"2015","journal-title":"Neuroimage"},{"key":"10.1016\/j.sleep.2019.12.024_bib26","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.neuroimage.2014.10.009","article-title":"Association between increased magnetic susceptibility of deep gray matter nuclei and decreased motor function in healthy adults","volume":"105","author":"Li","year":"2015","journal-title":"Neuroimage"},{"issue":"11","key":"10.1016\/j.sleep.2019.12.024_bib27","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1002\/hbm.22928","article-title":"Region-specific disturbed iron distribution in early idiopathic Parkinson's disease measured by quantitative susceptibility mapping","volume":"36","author":"He","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.sleep.2019.12.024_bib28","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.neuroimage.2013.05.127","article-title":"Human brain atlas for automated region of interest selection in quantitative susceptibility mapping: application to determine iron content in deep gray matter structures","volume":"82","author":"Lim","year":"2013","journal-title":"Neuroimage"},{"key":"10.1016\/j.sleep.2019.12.024_bib29","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.neuroimage.2013.09.011","article-title":"Evaluation of group-specific, whole-brain atlas generation using Volume-based Template Estimation (VTE): application to normal and Alzheimer's populations","volume":"84","author":"Zhang","year":"2014","journal-title":"Neuroimage"},{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib30","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1148\/radiology.208.2.9680575","article-title":"Doppler perfusion index: an interobserver and intraobserver reproducibility study","volume":"208","author":"Oppo","year":"1998","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.sleep.2019.12.024_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0059717","article-title":"Enhanced functional connectivity between putamen and supplementary motor area in Parkinson's disease patients","volume":"8","author":"Yu","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib32","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1037\/a0019077","article-title":"Conditional routing of information to the cortex: a model of the basal ganglia's role in cognitive coordination","volume":"117","author":"Stocco","year":"2010","journal-title":"Psychol Rev"},{"issue":"5","key":"10.1016\/j.sleep.2019.12.024_bib33","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1016\/j.neuron.2015.05.008","article-title":"Antagonistic but not symmetric regulation of primary motor cortex by basal ganglia direct and indirect pathways","volume":"86","author":"Oldenburg","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.sleep.2019.12.024_bib34","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.sleep.2016.06.003","article-title":"Connectome and molecular pharmacological differences in the dopaminergic system in restless legs syndrome (RLS): plastic changes and neuroadaptations that may contribute to augmentation","volume":"31","author":"Earley","year":"2017","journal-title":"Sleep Med"},{"issue":"4","key":"10.1016\/j.sleep.2019.12.024_bib35","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1093\/cercor\/bhu241","article-title":"Nigrostriatal dopamine acting on globus pallidus regulates sleep","volume":"26","author":"Qiu","year":"2016","journal-title":"Cerebr Cortex"},{"issue":"1","key":"10.1016\/j.sleep.2019.12.024_bib36","doi-asserted-by":"crossref","first-page":"9905","DOI":"10.1038\/s41598-017-10284-3","article-title":"Targeted disruption of supraspinal motor circuitry reveals a distributed network underlying Restless Legs Syndrome (RLS)-like movements in the rat","volume":"7","author":"Guo","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.sleep.2019.12.024_bib37","first-page":"1","article-title":"The variation of motor-related brain structure and its relation to abnormal motor behaviors in end-stage renal disease patients with restless legs syndrome","author":"Mu","year":"2018","journal-title":"Brain Imag Behav"},{"issue":"6","key":"10.1016\/j.sleep.2019.12.024_bib38","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.sleep.2014.12.029","article-title":"Mapping intrinsic functional brain changes and repetitive transcranial magnetic stimulation neuromodulation in idiopathic restless legs syndrome: a resting-state functional magnetic resonance imaging study","volume":"16","author":"Liu","year":"2015","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2019.12.024_bib39","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3389\/fneur.2018.00025","article-title":"Altered brain functional connectome in migraine with and without restless legs syndrome: a resting-state functional MRI study","volume":"9","author":"Yang","year":"2018","journal-title":"Front Neurol"},{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib40","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1212\/WNL.56.2.263","article-title":"MRI measurement of brain iron in patients with restless legs syndrome","volume":"56","author":"Allen","year":"2001","journal-title":"Neurology"},{"issue":"12","key":"10.1016\/j.sleep.2019.12.024_bib41","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1212\/01.wnl.0000325914.50764.a2","article-title":"T2 relaxometry and fMRI of the brain in late-onset restless legs syndrome","volume":"71","author":"Astrakas","year":"2008","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.sleep.2019.12.024_bib42","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3174\/ajnr.A2829","article-title":"Investigation of unmedicated early onset restless legs syndrome by voxel-based morphometry, T2 relaxometry, and functional MR imaging during the night-time hours","volume":"33","author":"Margariti","year":"2012","journal-title":"AJNR Am J Neuroradiol"},{"issue":"8","key":"10.1016\/j.sleep.2019.12.024_bib43","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1002\/mds.22070","article-title":"Multiregional brain iron deficiency in restless legs syndrome","volume":"23","author":"Godau","year":"2008","journal-title":"Mov Disord"},{"issue":"12","key":"10.1016\/j.sleep.2019.12.024_bib44","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s11940-018-0540-3","article-title":"Restless legs syndrome and other movement disorders of sleep-treatment update","volume":"20","author":"Salminen","year":"2018","journal-title":"Curr Treat Options Neurol"},{"issue":"1","key":"10.1016\/j.sleep.2019.12.024_bib45","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/mds.27482","article-title":"Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome","volume":"34","author":"Haschka","year":"2019","journal-title":"Mov Disord"},{"issue":"10","key":"10.1016\/j.sleep.2019.12.024_bib46","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.sleep.2009.01.006","article-title":"The dopaminergic neurons of the A11 system in RLS autopsy brains appear normal","volume":"10","author":"Earley","year":"2009","journal-title":"Sleep Med"},{"issue":"4","key":"10.1016\/j.sleep.2019.12.024_bib47","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.sleep.2004.01.012","article-title":"Dopamine and iron in the pathophysiology of restless legs syndrome (RLS)","volume":"5","author":"Allen","year":"2004","journal-title":"Sleep Med"},{"issue":"8","key":"10.1016\/j.sleep.2019.12.024_bib48","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1007\/s11064-017-2219-7","article-title":"Three types of A11 neurons project to the rat spinal cord","volume":"42","author":"Ozawa","year":"2017","journal-title":"Neurochem Res"},{"key":"10.1016\/j.sleep.2019.12.024_bib49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.brainres.2008.03.010","article-title":"Lack of D2 receptor mediated regulation of dopamine synthesis in A11 diencephalospinal neurons in male and female mice","volume":"1214","author":"Pappas","year":"2008","journal-title":"Brain Res"},{"key":"10.1016\/j.sleep.2019.12.024_bib50","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3389\/fnbeh.2018.00199","article-title":"Differential dopamine D1 and D3 receptor modulation and expression in the spinal cord of two mouse models of restless legs syndrome","volume":"12","author":"Meneely","year":"2018","journal-title":"Front Behav Neurosci"},{"issue":"5","key":"10.1016\/j.sleep.2019.12.024_bib51","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1179\/1607845414Y.0000000199","article-title":"Long-term effects of an oral iron chelator, deferasirox, in hemodialysis patients with iron overload","volume":"20","author":"Chen","year":"2015","journal-title":"Hematology"},{"issue":"4","key":"10.1016\/j.sleep.2019.12.024_bib52","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1681\/ASN.2017101088","article-title":"Hemodialysis induces an acute decline in cerebral blood flow in elderly patients","volume":"29","author":"Polinder-Bos","year":"2018","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.sleep.2019.12.024_bib53","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.mri.2019.04.003","article-title":"Clinical feasibility of brain quantitative susceptibility mapping","volume":"60","author":"Zhang","year":"2019","journal-title":"Magn Reson Imaging"},{"key":"10.1016\/j.sleep.2019.12.024_bib54","doi-asserted-by":"crossref","first-page":"20181016","DOI":"10.1259\/bjr.20181016","article-title":"Introduction to quantitative susceptibility mapping and susceptibility weighted imaging","author":"Ruetten","year":"2019","journal-title":"Br J Radiol"},{"issue":"2","key":"10.1016\/j.sleep.2019.12.024_bib55","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1177\/1073858418791763","article-title":"New insights into the neurobiology of restless legs syndrome","volume":"25","author":"Ferre","year":"2019","journal-title":"The Neuroscientist"},{"issue":"5","key":"10.1016\/j.sleep.2019.12.024_bib56","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/ana.410410513","article-title":"Cerebral generators involved in the pathogenesis of the restless legs syndrome","volume":"41","author":"Bucher","year":"1997","journal-title":"Ann Neurol"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945720300113?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945720300113?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T15:22:23Z","timestamp":1761405743000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945720300113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":56,"alternative-id":["S1389945720300113"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2019.12.024","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Different iron deposition patterns in hemodialysis patients with and without restless legs syndrome: a quantitative susceptibility mapping study","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2019.12.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}