{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:47:46Z","timestamp":1781077666746,"version":"3.54.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100014438","name":"Business Finland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014438","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006706","name":"Tampere Tuberculosis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006706","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Academy of Finland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004212","name":"Paivikki and Sakari Sohlberg Fundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004212","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.sleep.2021.02.020","type":"journal-article","created":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T12:16:38Z","timestamp":1613564198000},"page":"394-400","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Total durations of respiratory events are modulated within REM and NREM sleep by sleeping position and obesity in OSA patients"],"prefix":"10.1016","volume":"81","author":[{"given":"M.","family":"Rissanen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Oksenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"T\u00f6yr\u00e4s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Myllymaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Lepp\u00e4nen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.sleep.2021.02.020_bib1","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S2213-2600(19)30198-5","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis","volume":"7","author":"Benjafield","year":"2019","journal-title":"Lancet Respir Med"},{"issue":"8","key":"10.1016\/j.sleep.2021.02.020_bib2","first-page":"1311","article-title":"Obstructive sleep apnea is a common disorder in the population - a review on the epidemiology of sleep apnea","volume":"7","author":"Franklin","year":"2015","journal-title":"J Thoratic Dis"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib3","first-page":"139","article-title":"Sleep Med Rev. The effect of body posture on sleep-related breathing disorders: facts and therapeutic implications Sleep\u00a0Medicine Reviews","volume":"2","author":"Oksenberg","year":"1998"},{"issue":"17","key":"10.1016\/j.sleep.2021.02.020_bib4","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1056\/NEJM199304293281704","article-title":"The occurrence of sleep disordered breathing among middle aged adults","volume":"328","author":"Young","year":"1993","journal-title":"N\u00a0Engl J Med"},{"issue":"14","key":"10.1016\/j.sleep.2021.02.020_bib5","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1001\/jama.283.14.1829","article-title":"Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. sleep heart health study","volume":"283","author":"Nieto","year":"2000","journal-title":"J\u00a0Am Med Assoc"},{"issue":"11","key":"10.1016\/j.sleep.2021.02.020_bib6","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1164\/rccm.200505-702OC","article-title":"Association of sleep-disordered breathing and the occurrence of stroke","volume":"172","author":"Arzt","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib7","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1007\/s11325-013-0927-z","article-title":"Adjustment of apnea-hypopnea index with severity of obstruction events enhances detection of sleep apnea patients with the highest risk of severe health consequences","volume":"18","author":"Muraja-Murro","year":"2014","journal-title":"Sleep Breath"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib8","first-page":"119","article-title":"RemLogic plug-in enables clinical application of apnea-hypopnea index adjusted for severity of individual obstruction events","volume":"40","author":"Lepp\u00e4nen","year":"2016","journal-title":"J\u00a0Med Eng Technol"},{"issue":"1","key":"10.1016\/j.sleep.2021.02.020_bib9","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s12931-020-1284-7","article-title":"Cardiometabolic comorbidities in obstructive sleep apnea patients are related to disease severity, nocturnal hypoxemia, and decreased sleep quality","volume":"21","author":"Andr\u00e9","year":"2020","journal-title":"Respir Res"},{"issue":"4","key":"10.1016\/j.sleep.2021.02.020_bib10","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s11325-017-1513-6","article-title":"Severity of desaturation events differs between hypopnea and obstructive apnea events and is modulated by their duration in obstructive sleep apnea","volume":"21","author":"Kulkas","year":"2017","journal-title":"Sleep Breath"},{"issue":"7","key":"10.1016\/j.sleep.2021.02.020_bib11","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1164\/rccm.201804-0758OC","article-title":"Apnea\u2013Hypopnea event duration predicts mortality in men and women in the sleep heart health study","volume":"199","author":"Butler","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib12","doi-asserted-by":"crossref","first-page":"561","DOI":"10.5665\/sleep.3498","article-title":"Physiological mechanisms of upper airway hypotonia during REM sleep","volume":"37","author":"McSharry","year":"2014","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.sleep.2021.02.020_bib13","first-page":"48","article-title":"Obstructive sleep apnea related to rapid-eye-movement or non-rapid-eye-movement sleep: comparison of demographic, anthropometric, and polysomnographic features","volume":"42","author":"Sunnetcioglu","year":"2016","journal-title":"J\u00a0Bras Pneumol: publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia."},{"issue":"7","key":"10.1016\/j.sleep.2021.02.020_bib14","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.arbres.2008.12.003","article-title":"Clinical and polysomnographic features of rapid-eye-movement-specific sleep-disordered breathing","volume":"45","author":"Campos-Rodr\u00edguez","year":"2009","journal-title":"Arch Bronconeumol"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib15","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.sleep.2005.10.006","article-title":"Half of patients with obstructive sleep apnea have a higher NREM AHI than REM AHI","volume":"7","author":"Siddiqui","year":"2006","journal-title":"Sleep Med"},{"issue":"11","key":"10.1016\/j.sleep.2021.02.020_bib16","doi-asserted-by":"crossref","first-page":"114004","DOI":"10.1088\/1361-6579\/aae42c","article-title":"Differences in arousal probability and duration after apnea and hypopnea events in adult obstructive sleep apnea patients","volume":"39","author":"Lepp\u00e4nen","year":"2018","journal-title":"Physiol Meas"},{"issue":"5","key":"10.1016\/j.sleep.2021.02.020_bib17","first-page":"906","article-title":"Apnoea\u2013Hypopnoea index during rapid eye movement and non-rapid eye movement sleep in obstructive sleep apnoea","volume":"36","author":"Muraki","year":"2008","journal-title":"J\u00a0Int Med Res"},{"key":"10.1016\/j.sleep.2021.02.020_bib18","article-title":"NREM apnea and hypopnea duration varies across population groups and physiologic traits","author":"Borker","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"10.1016\/j.sleep.2021.02.020_bib19","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1007\/s11517-015-1290-y","article-title":"Amount of weight loss or gain influences the severity of respiratory events in sleep apnea","volume":"53","author":"Kulkas","year":"2015","journal-title":"Med Biol Eng Comput"},{"issue":"6","key":"10.1016\/j.sleep.2021.02.020_bib20","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1378\/chest.08-1311","article-title":"Rapid eye movement-related sleep-disordered breathing","volume":"134","author":"Koo","year":"2008","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.sleep.2021.02.020_bib21","doi-asserted-by":"crossref","first-page":"77","DOI":"10.4187\/respcare.06297","article-title":"Increase in body mass index decreases duration of apneas and hypopneas in obstructive sleep apnea","volume":"64","author":"Lepp\u00e4nen","year":"2019","journal-title":"Respir Care"},{"issue":"1","key":"10.1016\/j.sleep.2021.02.020_bib22","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1093\/sleep\/11.1.90","article-title":"Sleep apnea and body position during sleep","volume":"11","author":"George","year":"1988","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.sleep.2021.02.020_bib23","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s00408-013-9510-4","article-title":"Correlates of obstructive apnea duration","volume":"192","author":"Koo","year":"2014","journal-title":"Lung"},{"issue":"6","key":"10.1016\/j.sleep.2021.02.020_bib24","doi-asserted-by":"crossref","first-page":"813","DOI":"10.5664\/jcsm.6622","article-title":"Efficacy of the new generation of devices for positional therapy for patients with positional obstructive sleep apnea: a systematic review of the literature and meta-analysis","volume":"13","author":"Ravesloot","year":"2017","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"4","key":"10.1016\/j.sleep.2021.02.020_bib25","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1378\/chest.118.4.1018","article-title":"Association of body position with severity of apneic events in patients with severe nonpositional obstructive sleep apnea","volume":"118","author":"Oksenberg","year":"2000","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib26","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1002\/lary.20758","article-title":"Severe obstructive sleep apnea: sleepy versus nonsleepy patients","volume":"120","author":"Oksenberg","year":"2010","journal-title":"Laryngoscope"},{"key":"10.1016\/j.sleep.2021.02.020_bib27","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.sleep.2019.06.021","article-title":"Comparison of cardiac autonomic activity between positional and nonpositional obstructive sleep apnea using heart rate variability","volume":"64","author":"Byun","year":"2019","journal-title":"Sleep Med"},{"issue":"10","key":"10.1016\/j.sleep.2021.02.020_bib28","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1007\/s00405-006-0090-2","article-title":"The role of sleep position in obstructive sleep apnea syndrome","volume":"263","author":"Richard","year":"2006","journal-title":"Eur Arch Oto-Rhino-Laryngol"},{"key":"10.1016\/j.sleep.2021.02.020_bib29","series-title":"Positional therapy in obstructive sleep apnea","first-page":"53","article-title":"Prevalence of positional obstructive sleep apnea in patients undergoing polysomnography and the effect of sleep stage","author":"Shetty","year":"2014"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib30","first-page":"307","article-title":"The association between daytime sleepiness and sleep-disordered breathing in NREM and REM sleep","volume":"25","author":"Punjabi","year":"2002","journal-title":"Sleep"},{"issue":"9","key":"10.1016\/j.sleep.2021.02.020_bib31","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1164\/rccm.200908-1304OC","article-title":"Sleepiness, quality of life, and sleep maintenance in REM versus non-REM sleep-disordered breathing","volume":"181","author":"Chami","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.sleep.2021.02.020_bib32","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1093\/sleep\/22.5.667","article-title":"Sleep\u2013Related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research","volume":"22","year":"1999","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.sleep.2021.02.020_bib33","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1093\/sleep\/15.2.173","article-title":"American sleep disorders association. EEG arousals: scoring rules and examples","volume":"15","author":"Bonnet","year":"1992","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2021.02.020_bib34","series-title":"A\u00a0manual of standardized terminology techniques and scoring system for sleep stages of human subjects","year":"1968"},{"key":"10.1016\/j.sleep.2021.02.020_bib35","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A\u00a0new method for measuring daytime sleepiness: the Epworth Sleepiness Scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.sleep.2021.02.020_bib36","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/sleep\/9.4.519","article-title":"Guidelines for the Multiple sleep latency test (MSLT): a standard measure of sleepiness","volume":"9","author":"Carskadon","year":"1986","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.sleep.2021.02.020_bib37","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1093\/sleep\/7.2.110","article-title":"Effect of sleep position on sleep apnea severity","volume":"7","author":"Cartwright","year":"1984","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.sleep.2021.02.020_bib38","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.13066","article-title":"On the rise and fall of the apnea\u2212hypopnea index: a historical review and critical appraisal","volume":"29","author":"Pevernagie","year":"2020","journal-title":"J\u00a0Sleep Res"},{"issue":"4","key":"10.1016\/j.sleep.2021.02.020_bib39","first-page":"343","article-title":"REM-related obstructive sleep apnea: the effect of body position","volume":"6","author":"Oksenberg","year":"2010","journal-title":"J\u00a0Clin Sleep Med: JCSM: Off Publ Am Acad Sleep Med"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib40","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1378\/chest.112.3.629","article-title":"Positional vs nonpositional obstructive sleep apnea patients","volume":"112","author":"Oksenberg","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.sleep.2021.02.020_bib41","doi-asserted-by":"crossref","first-page":"21556","DOI":"10.1038\/s41598-020-77780-x","article-title":"Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea","volume":"10","author":"Hietakoste","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.sleep.2021.02.020_bib42","series-title":"36th annual international conference of the IEEE engineering in medicine and biology society, Chicago, IL","first-page":"270","article-title":"In: effect of apnea duration on apnea induced variations in cerebral blood flow velocity and arterial blood pressure","author":"Alex","year":"2014"},{"issue":"1","key":"10.1016\/j.sleep.2021.02.020_bib43","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jpsychores.2004.05.004","article-title":"Comparing MSLT and ESS in the measurement of excessive daytime sleepiness in obstructive sleep apnoea syndrome","volume":"58","author":"Fong","year":"2005","journal-title":"J\u00a0Psychosom Res"},{"issue":"1","key":"10.1016\/j.sleep.2021.02.020_bib44","doi-asserted-by":"crossref","first-page":"32","DOI":"10.17241\/smr.2018.00157","article-title":"Clinical and polysomnographic characteristics of patients with excessive daytime sleepiness","volume":"9","author":"Park","year":"2018","journal-title":"Sleep Med Res"},{"issue":"10","key":"10.1016\/j.sleep.2021.02.020_bib45","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.5664\/jcsm.3072","article-title":"Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea","volume":"9","author":"Ward","year":"2013","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.020_bib46","doi-asserted-by":"crossref","first-page":"505","DOI":"10.3389\/fneur.2018.00505","article-title":"Obstructive sleep apnea with or without excessive daytime sleepiness: clinical and experimental data-driven phenotyping","volume":"9","author":"Garbarino","year":"2018","journal-title":"Front Neurol"},{"issue":"3","key":"10.1016\/j.sleep.2021.02.020_bib47","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1183\/09031936.04.00099404","article-title":"Effects of obesity upon genioglossus structure and function in obstructive sleep apnoea","volume":"23","author":"Carrera","year":"2004","journal-title":"Eur Respir J"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945721001180?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945721001180?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T15:34:07Z","timestamp":1761406447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945721001180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":47,"alternative-id":["S1389945721001180"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2021.02.020","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Total durations of respiratory events are modulated within REM and NREM sleep by sleeping position and obesity in OSA patients","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2021.02.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}