{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:40:57Z","timestamp":1789681257508,"version":"4.0.1"},"reference-count":77,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.sleep.2021.02.056","type":"journal-article","created":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T08:30:04Z","timestamp":1615105804000},"page":"319-326","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["The impact of antiseizure medications on polysomnographic parameters: a systematic review and meta-analysis"],"prefix":"10.1016","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1371-1154","authenticated-orcid":false,"given":"Wei-Chih","family":"Yeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiang-Ru","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Ni","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Wei","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Fang","family":"Chien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-On","family":"Fong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuan-Ying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3101-0896","authenticated-orcid":false,"given":"You-Lin","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiu-Jung","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Sheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Yu","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Han","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8462-1311","authenticated-orcid":false,"given":"Tien-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5761-7800","authenticated-orcid":false,"given":"Ping-Tao","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9880-5944","authenticated-orcid":false,"given":"Chung-Yao","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2021.02.056_bib1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.smrv.2011.01.002","article-title":"Sleep disturbances in people with epilepsy; prevalence, impact and treatment","volume":"15","author":"van Golde","year":"2011","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2021.02.056_bib2","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.seizure.2019.04.019","article-title":"Prevalence of sleep disturbances in people with epilepsy and the impact on quality of life: a survey in secondary care","volume":"69","author":"Gutter","year":"2019","journal-title":"Seizure"},{"key":"10.1016\/j.sleep.2021.02.056_bib3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.spen.2015.03.005","article-title":"Sleep and epilepsy","volume":"22","author":"Jain","year":"2015","journal-title":"Semin Pediatr Neurol"},{"key":"10.1016\/j.sleep.2021.02.056_bib4","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.2147\/NDT.S136868","article-title":"Sleep disturbances among patients with epilepsy","volume":"13","author":"Staniszewska","year":"2017","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.1016\/j.sleep.2021.02.056_bib5","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.sleep.2018.09.004","article-title":"Sleep architecture in adults with epilepsy: a systematic review","volume":"53","author":"Sudbrack-Oliveira","year":"2019","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib6","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.seizure.2012.04.005","article-title":"Markedly disturbed sleep in medically refractory compared to controlled epilepsy - a clinical and polysomnography study","volume":"21","author":"Zanzmera","year":"2012","journal-title":"Seizure"},{"key":"10.1016\/j.sleep.2021.02.056_bib7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.14581\/jer.19002","article-title":"Antiepileptic drug therapy in patients with drug-resistant epilepsy","volume":"9","author":"Park","year":"2019","journal-title":"J Epilepsy Res"},{"key":"10.1016\/j.sleep.2021.02.056_bib8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF01243384","article-title":"Gabapentin augments whole blood serotonin in healthy young men","volume":"73","author":"Rao","year":"1988","journal-title":"J Neural Transm"},{"key":"10.1016\/j.sleep.2021.02.056_bib9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/sleep\/28.2.187","article-title":"A double-blind study in healthy volunteers to assess the effects on sleep of pregabalin compared with alprazolam and placebo","volume":"28","author":"Hindmarch","year":"2005","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2021.02.056_bib10","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.yebeh.2012.02.005","article-title":"Pregabalin increases slow-wave sleep and may improve attention in patients with partial epilepsy and insomnia","volume":"23","author":"Bazil","year":"2012","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.sleep.2021.02.056_bib11","doi-asserted-by":"crossref","first-page":"473","DOI":"10.5664\/jcsm.26911","article-title":"Exploratory polysomnographic evaluation of pregabalin on sleep disturbance in patients with epilepsy","volume":"3","author":"de Haas","year":"2007","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/j.1528-1167.2006.00376.x","article-title":"Effects of levetiracetam on nocturnal sleep and daytime vigilance in healthy volunteers","volume":"47","author":"Cicolin","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.sleep.2021.02.056_bib13","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0197-4580(00)00232-3","article-title":"The GABA uptake inhibitor tiagabine promotes slow wave sleep in normal elderly subjects","volume":"22","author":"Mathias","year":"2001","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.sleep.2021.02.056_bib14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1093\/sleep\/28.6.673","article-title":"Dose-response effects of tiagabine on the sleep of older adults","volume":"28","author":"Walsh","year":"2005","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2021.02.056_bib15","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/epi.12478","article-title":"Effects of epilepsy treatments on sleep architecture and daytime sleepiness: an evidence-based review of objective sleep metrics","volume":"55","author":"Jain","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.sleep.2021.02.056_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000100","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"6","author":"Liberati","year":"2009","journal-title":"PLoS Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib17","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1037\/pha0000148","article-title":"The efficacy and tolerability of paliperidone in mania of bipolar disorder: A preliminary meta-analysis","volume":"25","author":"Chang","year":"2017","journal-title":"Exp Clin Psychopharmacol"},{"key":"10.1016\/j.sleep.2021.02.056_bib18","doi-asserted-by":"crossref","first-page":"15908","DOI":"10.1038\/s41598-019-52205-6","article-title":"Therapeutic effects of methylphenidate for attention-deficit\/hyperactivity disorder in children with borderline intellectual functioning or intellectual disability: A systematic review and meta-analysis","volume":"9","author":"Sun","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.sleep.2021.02.056_bib19","doi-asserted-by":"crossref","first-page":"e2475","DOI":"10.1097\/MD.0000000000002475","article-title":"Significant effect of valproate augmentation therapy in patients with schizophrenia: A meta-analysis study","volume":"95","author":"Tseng","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.sleep.2021.02.056_bib20","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12888-016-0718-8","article-title":"Significant treatment effect of adjunct music therapy to standard treatment on the positive, negative, and mood symptoms of schizophrenic patients: a meta-analysis","volume":"16","author":"Tseng","year":"2016","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.sleep.2021.02.056_bib21","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.euroneuro.2016.03.001","article-title":"Light therapy in the treatment of patients with bipolar depression: A meta-analytic study","volume":"26","author":"Tseng","year":"2016","journal-title":"Eur Neuropsychopharmacol"},{"key":"10.1016\/j.sleep.2021.02.056_bib22","doi-asserted-by":"crossref","first-page":"g254","DOI":"10.1136\/bmj.g254","article-title":"Drug treatment of epilepsy in adults","volume":"348","author":"Schmidt","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.sleep.2021.02.056_bib23","doi-asserted-by":"crossref","first-page":"107966","DOI":"10.1016\/j.neuropharm.2020.107966","article-title":"Mechanisms of action of currently used antiseizure drugs","volume":"168","author":"Sills","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.sleep.2021.02.056_bib24","first-page":"693","article-title":"Dose effects of temazepam tablets on sleep","volume":"12","author":"Roehrs","year":"1986","journal-title":"Drugs Exp Clin Res"},{"key":"10.1016\/j.sleep.2021.02.056_bib25","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0197-4580(85)90006-5","article-title":"Efficacy of a reduced triazolam dose in elderly insomniacs","volume":"6","author":"Roehrs","year":"1985","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.sleep.2021.02.056_bib26","first-page":"118","article-title":"Medications for the treatment of sleep disorders: An overview","volume":"3","author":"Pagel","year":"2001","journal-title":"Prim Care Companion J Clin Psychiatry"},{"key":"10.1016\/j.sleep.2021.02.056_bib27","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1177\/0269881113503509","article-title":"Benzodiazepines: risks and benefits. A reconsideration","volume":"27","author":"Baldwin","year":"2013","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.sleep.2021.02.056_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.sleep.2021.02.056_bib29","series-title":"A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects","author":"Rechtschaffen","year":"1968"},{"key":"10.1016\/j.sleep.2021.02.056_bib30","series-title":"The AASM Manual for the Scoring of Sleep and associated events: Rules, Terminology and technical specifications, version 2.2","author":"Berry Rb","year":"2015"},{"key":"10.1016\/j.sleep.2021.02.056_bib31","doi-asserted-by":"crossref","first-page":"107064","DOI":"10.1016\/j.yebeh.2020.107064","article-title":"Rapid eye movement (REM) sleep and seizure control in idiopathic generalized epilepsy","volume":"107","author":"Hamdy","year":"2020","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.sleep.2021.02.056_bib32","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.sleep.2017.02.013","article-title":"Sleep architecture in patients with Juvenile Myoclonic Epilepsy","volume":"38","author":"Mekky","year":"2017","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib33","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ensci.2016.06.002","article-title":"How do people with drug-resistant mesial temporal lobe epilepsy sleep? A clinical and video-EEG with EOG and submental EMG for sleep staging study","volume":"4","author":"Scarlatelli-Lima","year":"2016","journal-title":"eNeurologicalSci"},{"key":"10.1016\/j.sleep.2021.02.056_bib34","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.sleep.2021.02.007","article-title":"Rapid eye movement sleep disturbance in patients with refractory epilepsy: A polysomnographic study","volume":"81","author":"Yeh","year":"2021","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib35","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1111\/j.1528-1167.2007.01461.x","article-title":"Global cognitive function in children with epilepsy: a community-based study","volume":"49","author":"Berg","year":"2008","journal-title":"Epilepsia"},{"key":"10.1016\/j.sleep.2021.02.056_bib36","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/jrsm.12","article-title":"A basic introduction to fixed-effect and random-effects models for meta-analysis","volume":"1","author":"Borenstein","year":"2010","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.sleep.2021.02.056_bib37","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib38","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1002\/jrsm.1230","article-title":"Basics of meta-analysis: I(2) is not an absolute measure of heterogeneity","volume":"8","author":"Borenstein","year":"2017","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.sleep.2021.02.056_bib39","series-title":"Cochrane handbook for systematic reviews of interventions","article-title":"10.4.3.1 Recommendations on testing for funnel plot asymmetry","author":"Higgins","year":"2011"},{"key":"10.1016\/j.sleep.2021.02.056_bib40","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.sleep.2021.02.056_bib41","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0006-341X.2000.00455.x","article-title":"Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"10.1016\/j.sleep.2021.02.056_bib42","first-page":"15","article-title":"Assessing the influence of a single study in meta-analysis","volume":"47","author":"Tobias","year":"1999","journal-title":"STATA technical bulletin"},{"key":"10.1016\/j.sleep.2021.02.056_bib43","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.yebeh.2005.08.001","article-title":"Effects of levetiracetam on sleep in normal volunteers","volume":"7","author":"Bazil","year":"2005","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.sleep.2021.02.056_bib44","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1111\/j.1530-0277.2008.00706.x","article-title":"A randomized double-blind pilot trial of gabapentin versus placebo to treat alcohol dependence and comorbid insomnia","volume":"32","author":"Brower","year":"2008","journal-title":"Alcohol Clin Exp Res"},{"key":"10.1016\/j.sleep.2021.02.056_bib45","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1159\/000054948","article-title":"Effects of carbamazepine on dexamethasone suppression and sleep electroencephalography in borderline personality disorder","volume":"45","author":"De la Fuente","year":"2002","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.sleep.2021.02.056_bib46","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s00415-004-0367-6","article-title":"Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa\/benserazid","volume":"251","author":"Eisensehr","year":"2004","journal-title":"J Neurol"},{"key":"10.1016\/j.sleep.2021.02.056_bib47","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1183\/09031936.00158413","article-title":"Zonisamide reduces obstructive sleep apnoea: a randomised placebo-controlled study","volume":"44","author":"Eskandari","year":"2014","journal-title":"Eur Respir J"},{"key":"10.1016\/j.sleep.2021.02.056_bib48","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.5664\/jcsm.4110","article-title":"A randomized, double-blind, placebo-controlled, multicenter, 28-day, polysomnographic study of gabapentin in transient insomnia induced by sleep phase advance","volume":"10","author":"Furey","year":"2014","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib49","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1212\/WNL.59.10.1573","article-title":"Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study","volume":"59","author":"Garcia-Borreguero","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2021.02.056_bib50","doi-asserted-by":"crossref","first-page":"1897","DOI":"10.1212\/WNL.0b013e3181e1ce73","article-title":"Treatment of restless legs syndrome with pregabalin: a double-blind, placebo-controlled study","volume":"74","author":"Garcia-Borreguero","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2021.02.056_bib51","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/sleep\/28.2.187","article-title":"A double-blind study in healthy volunteers to assess the effects on sleep of pregabalin compared with alprazolam and placebo","volume":"28","author":"Hindmarch","year":"2005","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2021.02.056_bib52","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/jsr.12495","article-title":"Gabapentin acutely increases the apnea-hypopnea index in older men: data from a randomized, double-blind, placebo-controlled study","volume":"26","author":"Piovezan","year":"2017","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2021.02.056_bib53","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.5664\/jcsm.4108","article-title":"A randomized, double-blind, single-dose, placebo-controlled, multicenter, polysomnographic study of gabapentin in transient insomnia induced by sleep phase advance","volume":"10","author":"Rosenberg","year":"2014","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib54","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/sleep\/29.3.335","article-title":"Effect of tiagabine on sleep in elderly subjects with primary insomnia: a randomized, double-blind, placebo-controlled study","volume":"29","author":"Roth","year":"2006","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2021.02.056_bib55","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1002\/acr.21595","article-title":"Effect of pregabalin on sleep in patients with fibromyalgia and sleep maintenance disturbance: a randomized, placebo-controlled, 2-way crossover polysomnography study","volume":"64","author":"Roth","year":"2012","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"10.1016\/j.sleep.2021.02.056_bib56","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.smrv.2016.03.002","article-title":"Not a single but multiple populations of GABAergic neurons control sleep","volume":"32","author":"Luppi","year":"2017","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2021.02.056_bib57","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0165-6147(99)01413-3","article-title":"The 'ABC' of GABA receptors","volume":"21","author":"Bormann","year":"2000","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.sleep.2021.02.056_bib58","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.jsmc.2010.08.002","article-title":"Drug-related sleep stage changes: Functional significance and clinical relevance","volume":"5","author":"Roehrs","year":"2010","journal-title":"Sleep Med Clin"},{"key":"10.1016\/j.sleep.2021.02.056_bib59","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/sleep\/22.1.33","article-title":"Role of GABAA receptors in the regulation of sleep: initial sleep responses to peripherally administered modulators and agonists","volume":"22","author":"Lancel","year":"1999","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2021.02.056_bib60","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.sleep.2005.05.004","article-title":"Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia","volume":"7","author":"Walsh","year":"2006","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2021.02.056_bib61","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1016\/j.mayocp.2016.07.024","article-title":"Benzodiazepine use in older adults: Dangers, management, and alternative therapies","volume":"91","author":"Markota","year":"2016","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.sleep.2021.02.056_bib62","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0127836","article-title":"Association between benzodiazepine use and dementia: A meta-analysis","volume":"10","author":"Zhong","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.sleep.2021.02.056_bib63","doi-asserted-by":"crossref","first-page":"i90","DOI":"10.1136\/bmj.i90","article-title":"Benzodiazepine use and risk of incident dementia or cognitive decline: prospective population based study","volume":"352","author":"Gray","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.sleep.2021.02.056_bib64","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/bcp.13153","article-title":"Impact of concomitant medications on obstructive sleep apnoea","volume":"83","author":"Jullian-Desayes","year":"2017","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.sleep.2021.02.056_bib65","doi-asserted-by":"crossref","first-page":"911","DOI":"10.3233\/JAD-181145","article-title":"Long-term trazodone use and cognition: A potential therapeutic role for slow-wave sleep enhancers","volume":"67","author":"La","year":"2019","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.sleep.2021.02.056_bib66","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.smrv.2012.11.001","article-title":"REM sleep dysregulation in depression: state of the art","volume":"17","author":"Palagini","year":"2013","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2021.02.056_bib67","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1093\/sleep\/25.8.56","article-title":"Relationship of epileptic seizures to sleep stage and sleep depth","volume":"25","author":"Minecan","year":"2002","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2021.02.056_bib68","doi-asserted-by":"crossref","first-page":"731","DOI":"10.2147\/NDT.S833","article-title":"Tiagabine: efficacy and safety in partial seizures - current status","volume":"4","author":"Bauer","year":"2008","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10.1016\/j.sleep.2021.02.056_bib69","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1046\/j.1528-1157.2001.36500.x","article-title":"Tiagabine: efficacy and safety in adjunctive treatment of partial seizures","volume":"42","author":"Crawford","year":"2001","journal-title":"Epilepsia"},{"key":"10.1016\/j.sleep.2021.02.056_bib70","doi-asserted-by":"crossref","first-page":"61","DOI":"10.2147\/NSS.S34842","article-title":"Sleep disturbance in mental health problems and neurodegenerative disease","volume":"5","author":"Anderson","year":"2013","journal-title":"Nat Sci Sleep"},{"key":"10.1016\/j.sleep.2021.02.056_bib71","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.jad.2012.08.015","article-title":"Polysomnographic sleep patterns of non-depressed, non-medicated children with generalized anxiety disorder","volume":"147","author":"Alfano","year":"2013","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sleep.2021.02.056_bib72","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.nlm.2015.01.004","article-title":"REM sleep and memory reorganization: Potential relevance for psychiatry and psychotherapy","volume":"122","author":"Landmann","year":"2015","journal-title":"Neurobiol Learn Mem"},{"key":"10.1016\/j.sleep.2021.02.056_bib73","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1097\/JCP.0b013e318172b45f","article-title":"Tiagabine in adult patients with generalized anxiety disorder: results from 3 randomized, double-blind, placebo-controlled, parallel-group studies","volume":"28","author":"Pollack","year":"2008","journal-title":"J Clin Psychopharmacol"},{"key":"10.1016\/j.sleep.2021.02.056_bib74","doi-asserted-by":"crossref","first-page":"66","DOI":"10.4088\/JCP.v67n0110","article-title":"Open-label tiagabine monotherapy for major depressive disorder with anxiety","volume":"67","author":"Carpenter","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.sleep.2021.02.056_bib75","doi-asserted-by":"crossref","first-page":"2764","DOI":"10.1038\/npp.2012.142","article-title":"The impact of gabapentin administration on brain GABA and glutamate concentrations: a 7T (1)H-MRS study","volume":"37","author":"Cai","year":"2012","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.sleep.2021.02.056_bib76","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.biopsycho.2016.11.010","article-title":"When a gold standard isn't so golden: Lack of prediction of subjective sleep quality from sleep polysomnography","volume":"123","author":"Kaplan","year":"2017","journal-title":"Biol Psychol"},{"key":"10.1016\/j.sleep.2021.02.056_bib77","doi-asserted-by":"crossref","first-page":"661","DOI":"10.2165\/11536200-000000000-00000","article-title":"A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin","volume":"49","author":"Bockbrader","year":"2010","journal-title":"Clin Pharmacokinet"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945721001593?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945721001593?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T15:30:50Z","timestamp":1761406250000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945721001593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":77,"alternative-id":["S1389945721001593"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2021.02.056","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The impact of antiseizure medications on polysomnographic parameters: a systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2021.02.056","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}