{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:52:58Z","timestamp":1790455978382,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["313348\/2017-0"],"award-info":[{"award-number":["313348\/2017-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/201612-4"],"award-info":[{"award-number":["2018\/201612-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2017\/02955-9"],"award-info":[{"award-number":["2017\/02955-9"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.sleep.2023.02.011","type":"journal-article","created":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T12:13:30Z","timestamp":1676463210000},"page":"42-48","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Muscle and visceral fat infiltration: A potential mechanism to explain the worsening of obstructive sleep apnea with age"],"prefix":"10.1016","volume":"104","author":[{"given":"Giovanna F.","family":"D'Angelo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 A.F.","family":"de Mello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiola","family":"Schorr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloisa","family":"Gebrim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni F.","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo F.","family":"Grad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Yanagimori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldo","family":"Lorenzi-Filho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6764-165X","authenticated-orcid":false,"given":"Pedro Rodrigues","family":"Genta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9918","key":"10.1016\/j.sleep.2023.02.011_bib1","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0140-6736(13)60734-5","article-title":"Adult obstructive sleep apnoea","volume":"383","author":"Jordan","year":"2014","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.sleep.2023.02.011_bib2","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S2213-2600(15)00043-0","article-title":"Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study","volume":"3","author":"Heinzer","year":"2015","journal-title":"Lancet Respir Med"},{"issue":"5","key":"10.1016\/j.sleep.2023.02.011_bib3","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.sleep.2009.10.005","article-title":"Obstructive sleep apnea syndrome in the Sao Paulo epidemiologic sleep study","volume":"11","author":"Tufik","year":"2010","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.sleep.2023.02.011_bib4","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1164\/rccm.200208-866OC","article-title":"Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging","volume":"168","author":"Schwab","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"10","key":"10.1016\/j.sleep.2023.02.011_bib5","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.5665\/sleep.4078","article-title":"Upper airway collapsibility is associated with obesity and hyoid position","volume":"37","author":"Genta","year":"2014","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.sleep.2023.02.011_bib6","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1136\/thx.2005.052084","article-title":"Effect of increased lung volume on sleep disordered breathing in patients with sleep apnoea","volume":"61","author":"Heinzer","year":"2006","journal-title":"Thorax"},{"issue":"7","key":"10.1016\/j.sleep.2023.02.011_bib7","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.5665\/sleep.3844","article-title":"Obstructive sleep apnea in older adults is a distinctly different physiological phenotype","volume":"37","author":"Edwards","year":"2014","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.sleep.2023.02.011_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjmed.2005.01.077","article-title":"Aging influences on pharyngeal anatomy and physiology: the predisposition to pharyngeal collapse","volume":"119","author":"Malhotra","year":"2006","journal-title":"Am J Med"},{"issue":"4","key":"10.1016\/j.sleep.2023.02.011_bib9","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.clnu.2012.10.004","article-title":"Health and ageing: a cross-sectional study of body composition","volume":"32","author":"Bazzocchi","year":"2013","journal-title":"Clin Nutr (Edinb)"},{"issue":"3","key":"10.1016\/j.sleep.2023.02.011_bib10","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1378\/chest.15-0638","article-title":"Different craniofacial characteristics predict upper airway collapsibility in Japanese-Brazilian and White men","volume":"149","author":"Schorr","year":"2016","journal-title":"Chest"},{"issue":"5","key":"10.1016\/j.sleep.2023.02.011_bib11","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1093\/sleep\/22.5.667","article-title":"Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force","volume":"22","year":"1999","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.sleep.2023.02.011_bib12","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1152\/japplphysiol.00508.2011","article-title":"Critical closing pressure during midazolam-induced sleep","volume":"111","author":"Genta","year":"2011","journal-title":"J\u00a0Appl Physiol"},{"issue":"11","key":"10.1016\/j.sleep.2023.02.011_bib13","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/j.metabol.2016.08.008","article-title":"Fat accumulation in the tongue is associated with male gender, abnormal upper airway patency and whole-body adiposity","volume":"65","author":"Godoy","year":"2016","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.sleep.2023.02.011_bib14","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1148\/radiology.211.1.r99ap15283","article-title":"Abdominal fat: standardized technique for measurement at CT","volume":"211","author":"Yoshizumi","year":"1999","journal-title":"Radiology"},{"issue":"8","key":"10.1016\/j.sleep.2023.02.011_bib15","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1093\/sleep\/32.8.1049","article-title":"Longitudinal evaluation of sleep-disordered breathing and sleep symptoms with change in quality of life: the Sleep Heart Health Study (SHHS)","volume":"32","author":"Silva","year":"2009","journal-title":"Sleep"},{"issue":"9","key":"10.1016\/j.sleep.2023.02.011_bib16","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1093\/gerona\/glq071","article-title":"Incident sleep disordered breathing in old age","volume":"65","author":"Bliwise","year":"2010","journal-title":"J\u00a0Gerontol A Biol Sci Med Sci"},{"issue":"6","key":"10.1016\/j.sleep.2023.02.011_bib17","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1378\/chest.06-2653","article-title":"The influence of aging on pharyngeal collapsibility during sleep","volume":"131","author":"Eikermann","year":"2007","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.sleep.2023.02.011_bib18","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1152\/japplphysiol.00045.2008","article-title":"Contribution of male sex, age, and obesity to mechanical instability of the upper airway during sleep","volume":"104","author":"Kirkness","year":"2008","journal-title":"J\u00a0Appl Physiol"},{"issue":"3","key":"10.1016\/j.sleep.2023.02.011_bib19","first-page":"103","article-title":"Age related shift in visceral fat","volume":"8","author":"Hunter","year":"2010","journal-title":"Int J Body Compos Res"},{"issue":"2","key":"10.1016\/j.sleep.2023.02.011_bib20","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/oby.21328","article-title":"Myosteatosis increases with aging and is associated with incident diabetes in African ancestry men","volume":"24","author":"Miljkovic","year":"2016","journal-title":"Obesity"},{"issue":"1","key":"10.1016\/j.sleep.2023.02.011_bib21","doi-asserted-by":"crossref","first-page":"6550","DOI":"10.1038\/s41598-018-24750-z","article-title":"Associations of obstructive sleep apnea with truncal skeletal muscle mass and density","volume":"8","author":"Matsumoto","year":"2018","journal-title":"Sci Rep"},{"issue":"10","key":"10.1016\/j.sleep.2023.02.011_bib22","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1007\/s40618-020-01255-z","article-title":"Molecular basis of ageing in chronic metabolic diseases","volume":"43","author":"Spinelli","year":"2020","journal-title":"J\u00a0Endocrinol Invest"},{"issue":"10","key":"10.1016\/j.sleep.2023.02.011_bib23","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1002\/oby.20346","article-title":"Abdominal myosteatosis is independently associated with hyperinsulinemia and insulin resistance among older men without diabetes","volume":"21","author":"Miljkovic","year":"2013","journal-title":"Obesity"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945723000588?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945723000588?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T19:25:11Z","timestamp":1778613911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945723000588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":23,"alternative-id":["S1389945723000588"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2023.02.011","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Muscle and visceral fat infiltration: A potential mechanism to explain the worsening of obstructive sleep apnea with age","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2023.02.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}