{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T12:41:13Z","timestamp":1780317673778,"version":"3.54.1"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.sleep.2023.03.006","type":"journal-article","created":{"date-parts":[[2023,3,11]],"date-time":"2023-03-11T19:42:46Z","timestamp":1678563766000},"page":"37-42","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Narcolepsy is associated with an increased risk of HLA-related autoimmune diseases: Evidence from a nationwide healthcare system data in South Korea"],"prefix":"10.1016","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1935-4066","authenticated-orcid":false,"given":"Jihye","family":"Oh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunhae","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoo-Hyun","family":"Um","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sei Hoon","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Chul","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8676","key":"10.1016\/j.sleep.2023.03.006_bib1","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1016\/S0140-6736(89)91977-6","article-title":"Familial patterns of narcolepsy","volume":"2","author":"Guilleminault","year":"1989","journal-title":"Lancet"},{"issue":"S5","key":"10.1016\/j.sleep.2023.03.006_bib2","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S0893-133X(01)00317-7","article-title":"A\u00a0brief history of hypocretin\/orexin and narcolepsy","volume":"25","author":"Siegel","year":"2001","journal-title":"Neuropsychopharmacology"},{"issue":"12","key":"10.1016\/j.sleep.2023.03.006_bib3","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.humimm.2009.07.015","article-title":"Human leukocyte antigen-G polymorphism in relation to expression, function, and disease","volume":"70","author":"Larsen","year":"2009","journal-title":"Hum Immunol"},{"issue":"6","key":"10.1016\/j.sleep.2023.03.006_bib4","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/ng.372","article-title":"Narcolepsy is strongly associated with the TCR alpha locus HHS Public Access Author manuscript","volume":"41","author":"Hallmayer","year":"2009","journal-title":"Nat Genet"},{"issue":"5","key":"10.1016\/j.sleep.2023.03.006_bib5","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1093\/brain\/awq086","article-title":"Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss","volume":"133","author":"Fontana","year":"2010","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.sleep.2023.03.006_bib6","doi-asserted-by":"crossref","first-page":"4","DOI":"10.21037\/atm.2016.12.63","article-title":"Narcolepsy and influenza vaccination-induced autoimmunity","volume":"5","author":"Ahmed","year":"2017","journal-title":"Ann Transl Med"},{"issue":"3","key":"10.1016\/j.sleep.2023.03.006_bib7","doi-asserted-by":"crossref","first-page":"581","DOI":"10.5665\/sleep.5532","article-title":"Narcolepsy-associated HLA class I alleles implicate cell-mediated cytotoxicity","volume":"39","author":"Tafti","year":"2016","journal-title":"Sleep"},{"issue":"11","key":"10.1016\/j.sleep.2023.03.006_bib8","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/ng.2792","article-title":"Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sj\u00f6gren\u2019s syndrome","volume":"45","author":"Lessard","year":"2013","journal-title":"Nat Genet"},{"key":"10.1016\/j.sleep.2023.03.006_bib9","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1749-6632.2009.04642.x","article-title":"Human leukocyte antigen-DRB1 and -DQB1 genotyping in Lupus patients with and without antiphospholipid syndrome","volume":"1173","author":"Kapitany","year":"2009","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"10.1016\/j.sleep.2023.03.006_bib10","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.rdc.2017.04.003","article-title":"Human leukocyte antigen\u2013disease associations in rheumatoid arthritis","volume":"43","author":"van Drongelen","year":"2017","journal-title":"Rheum Dis Clin N Am"},{"issue":"4","key":"10.1016\/j.sleep.2023.03.006_bib11","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.3892\/mmr.2017.6248","article-title":"Role of HLA-B27 in the pathogenesis of ankylosing spondylitis (Review)","volume":"15","author":"Chen","year":"2017","journal-title":"Mol Med Rep"},{"issue":"5","key":"10.1016\/j.sleep.2023.03.006_bib12","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsz277","article-title":"Obesity and other medical comorbidities among NT1 patients after the Norwegian H1N1 influenza epidemic and vaccination campaign","volume":"43","author":"Nordstrand","year":"2020","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2023.03.006_bib13","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.2147\/NSS.S317746","article-title":"The association between asthma and narcolepsy: a nationwide case-control study in Taiwan","volume":"13","author":"Chen","year":"2021","journal-title":"Nat Sci Sleep"},{"issue":"12","key":"10.1016\/j.sleep.2023.03.006_bib14","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.5665\/sleep.5254","article-title":"Allergies and disease severity in childhood narcolepsy: preliminary findings","volume":"38","author":"Aydinoz","year":"2015","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.sleep.2023.03.006_bib15","doi-asserted-by":"crossref","first-page":"835","DOI":"10.5665\/sleep.2706","article-title":"Comorbidity and mortality of narcolepsy: a controlled retro- and prospective national study","volume":"36","author":"Jennum","year":"2013","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2023.03.006_bib16","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1212\/WNL.0000000000003432","article-title":"Comorbidity between central disorders of hypersomnolence and immune-based disorders","volume":"88","author":"Barateau","year":"2017","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.sleep.2023.03.006_bib17","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1073\/pnas.0308458100","article-title":"Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy","volume":"101","author":"Siebold","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6","key":"10.1016\/j.sleep.2023.03.006_bib18","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1111\/jsr.12420","article-title":"Diagnostic delay in narcolepsy type 1: combining the patients' and the doctors' perspectives","volume":"25","author":"Taddei","year":"2016","journal-title":"J\u00a0Sleep Res"},{"issue":"10","key":"10.1016\/j.sleep.2023.03.006_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0204799","article-title":"Incidence rates of narcolepsy diagnoses in Taiwan, Canada, and Europe: the use of statistical simulation to evaluate methods for the rapid assessment of potential safety issues on a population level in the SOMNIA study","volume":"13","author":"Dodd","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.sleep.2023.03.006_bib20","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.smrv.2017.06.006","article-title":"Incidence of narcolepsy after H1N1 influenza and vaccinations: systematic review and meta-analysis","volume":"38","author":"Sarkanen","year":"2018","journal-title":"Sleep Med Rev"},{"issue":"10","key":"10.1016\/j.sleep.2023.03.006_bib21","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s40263-017-0464-6","article-title":"Narcolepsy type 1 as an autoimmune disorder: evidence, and implications for pharmacological treatment","volume":"31","author":"Barateau","year":"2017","journal-title":"CNS Drugs"},{"issue":"July 2009","key":"10.1016\/j.sleep.2023.03.006_bib22","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.sleep.2018.10.036","article-title":"Narcolepsy and 2009 H1N1 pandemic vaccination in Taiwan","volume":"66","author":"Huang","year":"2020","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2023.03.006_bib23","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.sleep.2019.07.022","article-title":"Prevalence of attention deficit hyperactivity disorder symptoms in narcolepsy: a systematic review","volume":"65","author":"Kim","year":"2020","journal-title":"Sleep Med"},{"issue":"3","key":"10.1016\/j.sleep.2023.03.006_bib24","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.psychres.2014.11.071","article-title":"Internalized stigma and its psychosocial correlates in Korean patients with serious mental illness","volume":"225","author":"Kim","year":"2015","journal-title":"Psychiatr Res"},{"issue":"11","key":"10.1016\/j.sleep.2023.03.006_bib25","first-page":"1012","article-title":"HLA DQB1\u22170602 is associated with cataplexy in 509 narcoleptic patients","volume":"20","author":"E Mignot","year":"1997","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.sleep.2023.03.006_bib26","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.humimm.2006.10.006","article-title":"DQB1\u22170301 and DQB1\u22170601 modulate narcolepsy susceptibility in Koreans","volume":"68","author":"Hong","year":"2007","journal-title":"Hum Immunol"},{"issue":"4","key":"10.1016\/j.sleep.2023.03.006_bib27","doi-asserted-by":"crossref","DOI":"10.3390\/cells9040880","article-title":"Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis","volume":"9","author":"Lin","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.sleep.2023.03.006_bib28","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1056\/NEJMra1004965","article-title":"The pathogenesis of rheumatoid arthritis","volume":"165","author":"Mcinnes","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.sleep.2023.03.006_bib29","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.clim.2017.04.005","article-title":"Sjogren's syndrome: clinical aspects","volume":"182","author":"Vivino","year":"2017","journal-title":"Clin Immunol"},{"issue":"6","key":"10.1016\/j.sleep.2023.03.006_bib30","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nrrheum.2017.56","article-title":"Pathogenesis of ankylosing spondylitis-recent advances and future directions","volume":"13","author":"Ranganathan","year":"2017","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.sleep.2023.03.006_bib31","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1086\/318799","article-title":"Complex HLA-DR and-DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups","volume":"68","author":"Mignot","year":"2001","journal-title":"Am J Hum Genet"},{"issue":"6","key":"10.1016\/j.sleep.2023.03.006_bib32","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/nrg2361","article-title":"Linkage disequilibrium - understanding the evolutionary past and mapping the medical future","volume":"9","author":"Slatkin","year":"2008","journal-title":"Nat Rev Genet"},{"issue":"3","key":"10.1016\/j.sleep.2023.03.006_bib33","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4078\/jrd.2021.28.3.119","article-title":"Clinical study using healthcare claims database","volume":"28","author":"Park","year":"2021","journal-title":"J.\u00a0Rheum. Dis."}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138994572300093X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S138994572300093X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T15:41:40Z","timestamp":1761406900000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S138994572300093X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":33,"alternative-id":["S138994572300093X"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2023.03.006","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Narcolepsy is associated with an increased risk of HLA-related autoimmune diseases: Evidence from a nationwide healthcare system data in South Korea","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2023.03.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}