{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T09:23:36Z","timestamp":1787909016202,"version":"build-2784847793"},"reference-count":159,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T00:00:00Z","timestamp":1749340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001665","name":"French National Research Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005760","name":"University of Gothenburg","doi-asserted-by":"publisher","award":["166432"],"award-info":[{"award-number":["166432"]}],"id":[{"id":"10.13039\/501100005760","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019979","name":"Fondation Universit\u00e9 Grenoble Alpes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019979","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009886","name":"American Academy of Sleep Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009886","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018870","name":"Swedish Heart and Lung Association","doi-asserted-by":"publisher","award":["20180585"],"award-info":[{"award-number":["20180585"]}],"id":[{"id":"10.13039\/100018870","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.sleep.2025.106607","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T21:07:29Z","timestamp":1749157649000},"page":"106607","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Hypersomnolence in focus: a white paper of the 6th Think Tank World Sleep Forum"],"prefix":"10.1016","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3992-3892","authenticated-orcid":false,"given":"Alessandro","family":"Silvani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Bassetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Bradicich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Dodel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Ferini Strambi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6ran","family":"Hajak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Hedner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Heinzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sogol","family":"Javaheri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poul","family":"Jennum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Kallweit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramin","family":"Khatami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert Jan","family":"Lammers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Pepin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Pizza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.","family":"Plante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Plazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winfried","family":"Randerath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Santamaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Schiza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Sundelin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Troxel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Manconi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.sleep.2025.106607_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2020.101306","article-title":"Diagnosis of central disorders of hypersomnolence: a reappraisal by European experts","volume":"52","author":"Lammers","year":"2020","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib2","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1093\/sleep\/32.6.753","article-title":"Idiopathic hypersomnia with and without long sleep time: a controlled series of 75 patients","volume":"32","author":"Vernet","year":"2009","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib3","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s10072-023-07232-7","article-title":"Role of sleep in neurodegeneration: the consensus report of the 5th Think Tank World Sleep Forum","volume":"45","author":"Ferini-Strambi","year":"2024","journal-title":"Neurol Sci"},{"key":"10.1016\/j.sleep.2025.106607_bib4","doi-asserted-by":"crossref","first-page":"155","DOI":"10.2147\/NSS.S188911","article-title":"Sleep inertia: current insights","volume":"11","author":"Hilditch","year":"2019","journal-title":"Nat Sci Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib5","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.smrv.2016.08.005","article-title":"Waking up is the hardest thing I do all day: sleep inertia and sleep drunkenness","volume":"35","author":"Trotti","year":"2017","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1001\/archgenpsychiatry.2011.1240","article-title":"Operational definitions and algorithms for excessive sleepiness in the general population: implications for DSM-5 nosology","volume":"69","author":"Ohayon","year":"2012","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.sleep.2025.106607_bib7","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.22837","article-title":"Association of sleep duration with all- and major-cause mortality among adults in Japan, China, Singapore, and korea","volume":"4","author":"Svensson","year":"2021","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.sleep.2025.106607_bib8","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1002\/ana.23818","article-title":"Excessive sleep duration and quality of life","volume":"73","author":"Ohayon","year":"2013","journal-title":"Ann Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib9","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1055\/s-0035-1550152","article-title":"Narcolepsy during childhood: an update","volume":"46","author":"Rocca","year":"2015","journal-title":"Neuropediatrics"},{"key":"10.1016\/j.sleep.2025.106607_bib10","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1542\/peds.109.3.449","article-title":"Inattention, hyperactivity, and symptoms of sleep-disordered breathing","volume":"109","author":"Chervin","year":"2002","journal-title":"Pediatrics"},{"key":"10.1016\/j.sleep.2025.106607_bib11","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.5665\/sleep.4910","article-title":"Attention-deficit\/hyperactivity disorder (ADHD) symptoms in pediatric narcolepsy: a cross-sectional study","volume":"38","author":"Lecendreux","year":"2015","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib12","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3109\/07853890.2015.1074271","article-title":"Age and gender variations of sleep in subjects without sleep disorders","volume":"47","author":"Luca","year":"2015","journal-title":"Ann Med"},{"key":"10.1016\/j.sleep.2025.106607_bib13","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.5664\/jcsm.9620","article-title":"Recommended protocols for the multiple sleep latency test and maintenance of wakefulness test in adults: guidance from the American Academy of sleep medicine","volume":"17","author":"Krahn","year":"2021","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib14","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/0013-4694(78)90162-1","article-title":"Excessive daytime sleepiness in man: multiple sleep latency measurement in narcoleptic and control subjects","volume":"45","author":"Richardson","year":"1978","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.sleep.2025.106607_bib15","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1046\/j.1365-2869.2000.00177.x","article-title":"Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the Epworth sleepiness scale: failure of the MSLT as a gold standard","volume":"9","author":"Johns","year":"2000","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib16","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsac091","article-title":"Usefulness of the maintenance of wakefulness test in central disorders of hypersomnolence: a scoping review","volume":"45","author":"Bijlenga","year":"2022","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib17","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0013-4694(97)00010-2","article-title":"A normative study of the maintenance of wakefulness test (MWT)","volume":"103","author":"Doghramji","year":"1997","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"10.1016\/j.sleep.2025.106607_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.neucli.2024.102949","article-title":"Long sleep time and excessive need for sleep: state of the art and perspectives","volume":"54","author":"Evangelista","year":"2024","journal-title":"Neurophysiol Clin"},{"key":"10.1016\/j.sleep.2025.106607_bib19","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/ana.25141","article-title":"Alternative diagnostic criteria for idiopathic hypersomnia: a 32\u2010hour protocol","volume":"83","author":"Evangelista","year":"2018","journal-title":"Ann Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib20","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.5664\/jcsm.9884","article-title":"The Psychomotor Vigilance Test as a measure of alertness and sleep inertia in people with central disorders of hypersomnolence","volume":"18","author":"Trotti","year":"2022","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib21","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsz101","article-title":"Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations","volume":"42","author":"Barfield","year":"2019","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib22","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/s10038-022-01015-2","article-title":"A variant in orexin receptor-2 is associated with self-reported daytime sleepiness in the Japanese population","volume":"67","author":"Miyagawa","year":"2022","journal-title":"J Hum Genet"},{"key":"10.1016\/j.sleep.2025.106607_bib23","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1038\/s41467-019-11456-7","article-title":"Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes","volume":"10","author":"Wang","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.sleep.2025.106607_bib24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.sleep.2016.08.007","article-title":"Self-reported exposure to traffic pollution in relation to daytime sleepiness and habitual snoring: a questionnaire study in seven North-European cities","volume":"24","author":"Gislason","year":"2016","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib25","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.sleep.2014.10.011","article-title":"Bidirectional interactions between the baroreceptor reflex and arousal: an update","volume":"16","author":"Silvani","year":"2015","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib26","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1212\/WNL.57.5.879","article-title":"Vagus nerve stimulation reduces daytime sleepiness in epilepsy patients","volume":"57","author":"Malow","year":"2001","journal-title":"Neurology"},{"key":"10.1016\/j.sleep.2025.106607_bib27","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsw033","article-title":"Objective, but not subjective, sleepiness is associated with inflammation in sleep apnea","volume":"40","author":"Li","year":"2017","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib28","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/1742-2094-9-91","article-title":"Disrupted sleep without sleep curtailment induces sleepiness and cognitive dysfunction via the tumor necrosis factor-\u03b1 pathway","volume":"9","author":"Ramesh","year":"2012","journal-title":"J Neuroinflammation"},{"key":"10.1016\/j.sleep.2025.106607_bib29","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.smrv.2018.10.001","article-title":"Local sleep","volume":"43","author":"Krueger","year":"2019","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib30","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.neuron.2010.11.032","article-title":"Sleep state switching","volume":"68","author":"Saper","year":"2010","journal-title":"Neuron"},{"key":"10.1016\/j.sleep.2025.106607_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2022.08.027","article-title":"Cardiovascular baroreflex circuit moonlights in sleep control","author":"Yao","year":"2022","journal-title":"Neuron"},{"key":"10.1016\/j.sleep.2025.106607_bib32","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/ana.26217","article-title":"Thalamic influence on slow wave slope renormalization during sleep","volume":"90","author":"Jaramillo","year":"2021","journal-title":"Ann Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib33","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/s41593-022-01236-w","article-title":"Neuro-orchestration of sleep and wakefulness","volume":"26","author":"Sulaman","year":"2023","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.sleep.2025.106607_bib34","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0306-4522(00)00220-7","article-title":"Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study","volume":"99","author":"Porkka-Heiskanen","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.sleep.2025.106607_bib35","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/s41586-018-0218-8","article-title":"Quantitative phosphoproteomic analysis of the molecular substrates of sleep need","volume":"558","author":"Wang","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.sleep.2025.106607_bib36","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3001813","article-title":"Distinct phosphorylation states of mammalian CaMKII\u03b2 control the induction and maintenance of sleep","volume":"20","author":"Tone","year":"2022","journal-title":"PLoS Biol"},{"key":"10.1016\/j.sleep.2025.106607_bib37","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2112225119","article-title":"The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin\/orexin and modulates the wake to sleep ratio","volume":"119","author":"Holm","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sleep.2025.106607_bib38","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2220911120","article-title":"Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy","volume":"120","author":"Seifinejad","year":"2023","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.sleep.2025.106607_bib39","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsac076","article-title":"Implications of sympathetic activation for objective versus self-reported daytime sleepiness in obstructive sleep apnea","volume":"45","author":"Chen","year":"2022","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib40","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.2147\/NSS.S319675","article-title":"Excessive daytime sleepiness and cardiovascular mortality in us adults: a nhanes 2005\u20132008 follow-up study","volume":"13","author":"Li","year":"2021","journal-title":"Nat Sci Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib41","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/jsr.12158","article-title":"Subjective sleepiness is a sensitive indicator of insufficient sleep and impaired waking function","volume":"23","author":"\u00c5kerstedt","year":"2014","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib42","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsz291","article-title":"Sleepiness as motivation: a potential mechanism for how sleep deprivation affects behavior","volume":"43","author":"Axelsson","year":"2020","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib43","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.13933","article-title":"Subjective awareness of sleepiness while driving in younger and older adults","volume":"33","author":"Cai","year":"2024","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib44","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsae211","article-title":"Predictors of driving risk in patients with obstructive sleep apnea syndrome treated by continuous positive airway pressure: a French multicenter prospective cohort","volume":"47","author":"Coelho","year":"2024","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib45","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsab123","article-title":"Sleepiness is a signal to go to bed: data and model simulations","volume":"44","author":"Shochat","year":"2021","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib46","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1002\/lary.24729","article-title":"Does surgery for obstructive sleep apnea improve depression and sleepiness?","volume":"124","author":"Ishman","year":"2014","journal-title":"Laryngoscope"},{"key":"10.1016\/j.sleep.2025.106607_bib47","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S2213-2600(15)00043-0","article-title":"Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study","volume":"3","author":"Heinzer","year":"2015","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.sleep.2025.106607_bib48","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx214","article-title":"Recognizable clinical subtypes of obstructive sleep apnea across international sleep centers: a cluster analysis","volume":"41","author":"Keenan","year":"2018","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib49","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01958-2021","article-title":"Comorbid insomnia and sleep apnoea is associated with all-cause mortality","volume":"60","author":"Lechat","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.sleep.2025.106607_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0163439","article-title":"Clinical phenotypes and comorbidity in European sleep apnoea patients","volume":"11","author":"Saaresranta","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.sleep.2025.106607_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2021.101519","article-title":"Bi-directional relationships between co-morbid insomnia and sleep apnea (COMISA)","volume":"60","author":"Sweetman","year":"2021","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib52","doi-asserted-by":"crossref","first-page":"240","DOI":"10.3390\/clockssleep4020022","article-title":"Socioeconomic position and excessive daytime sleepiness: a systematic review of social epidemiological studies","volume":"4","author":"Bendaoud","year":"2022","journal-title":"Clocks Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib53","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1164\/rccm.201808-1509OC","article-title":"Symptom subtypes of obstructive sleep apnea predict incidence of cardiovascular outcomes","volume":"200","author":"Mazzotti","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2025.106607_bib54","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1136\/thoraxjnl-2017-210431","article-title":"Polysomnographic phenotypes and their cardiovascular implications in obstructive sleep apnoea","volume":"73","author":"Zinchuk","year":"2018","journal-title":"Thorax"},{"key":"10.1016\/j.sleep.2025.106607_bib55","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1183\/13993003.01148-2015","article-title":"Obstructive sleep apnoea in the general population: highly prevalent but minimal symptoms","volume":"47","author":"Arnardottir","year":"2016","journal-title":"Eur Respir J"},{"key":"10.1016\/j.sleep.2025.106607_bib56","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.chest.2020.03.053","article-title":"The sleep apnea-specific hypoxic burden predicts incident heart failure","volume":"158","author":"Azarbarzin","year":"2020","journal-title":"Chest"},{"key":"10.1016\/j.sleep.2025.106607_bib57","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.13066","article-title":"On the rise and fall of the apnea-hypopnea index: a historical review and critical appraisal","volume":"29","author":"Pevernagie","year":"2020","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib58","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.02616-2017","article-title":"Challenges and perspectives in obstructive sleep apnoea: report by an ad hoc working group of the sleep disordered breathing group of the European Respiratory Society and the European Sleep Research Society","volume":"52","author":"Randerath","year":"2018","journal-title":"Eur Respir J"},{"key":"10.1016\/j.sleep.2025.106607_bib59","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1093\/eurheartj\/ehz274","article-title":"Hypoxic burden captures sleep apnoea-specific nocturnal hypoxaemia","volume":"40","author":"Azarbarzin","year":"2019","journal-title":"Eur Heart J"},{"key":"10.1016\/j.sleep.2025.106607_bib60","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1164\/rccm.202206-1223OC","article-title":"Pulse wave amplitude drops index: a biomarker of cardiovascular risk in obstructive sleep apnea","volume":"207","author":"Solelhac","year":"2023","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2025.106607_bib61","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.sleep.2022.02.015","article-title":"\u201cSleepiness\u201d in obstructive sleep apnea: getting into deep water","volume":"92","author":"Kallweit","year":"2022","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib62","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/sleep\/32.3.382","article-title":"Daytime sleepiness and driving performance in patients with obstructive sleep apnea: comparison of the MSLT, the MWT, and a simulated driving task","volume":"32","author":"Pizza","year":"2009","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib63","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01371-2024","article-title":"The modified Baveno classification for obstructive sleep apnoea - development and evaluation based on the ESADA database","author":"Matthes","year":"2024","journal-title":"Eur Respir J"},{"key":"10.1016\/j.sleep.2025.106607_bib64","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/S2213-2600(18)30059-6","article-title":"Challenges in obstructive sleep apnoea","volume":"6","author":"McNicholas","year":"2018","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.sleep.2025.106607_bib65","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1164\/rccm.202202-0366OC","article-title":"Positive airway pressure adherence, mortality, and cardiovascular events in patients with sleep apnea","volume":"206","author":"Gerv\u00e8s-Pinqui\u00e9","year":"2022","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.sleep.2025.106607_bib66","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.chest.2020.02.036","article-title":"Update on persistent excessive daytime sleepiness in OSA","volume":"158","author":"Javaheri","year":"2020","journal-title":"Chest"},{"key":"10.1016\/j.sleep.2025.106607_bib67","article-title":"Predictors of the efficacy for daytime sleepiness in patients with obstructive sleep apnea with continual positive airway pressure therapy: a meta-analysis of randomized controlled trials","volume":"13","author":"Li","year":"2022","journal-title":"Front Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2024.102843","article-title":"Comparative efficacy, safety and benefit\/risk of alerting agents for excessive daytime sleepiness in patients with obstructive sleep apnoea: a network meta-analysis","volume":"76","author":"P\u00e9pin","year":"2024","journal-title":"eClinicalMedicine"},{"key":"10.1016\/j.sleep.2025.106607_bib69","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.sleep.2023.10.001","article-title":"Recommendations for clinical management of excessive daytime sleepiness in obstructive sleep apnoea \u2013 a Delphi consensus study","volume":"112","author":"Steier","year":"2023","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib70","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0230-2021","article-title":"Investigation and management of residual sleepiness in CPAP-treated patients with obstructive sleep apnoea: the European view","volume":"31","author":"Craig","year":"2022","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib71","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsab264","article-title":"Continuous positive airway pressure and adverse cardiovascular events in obstructive sleep apnea: are participants of randomized trials representative of sleep clinic patients?","volume":"45","author":"Reynor","year":"2022","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib72","first-page":"718","article-title":"Cardiovascular effects of obstructive sleep apnoea and effects of continuous positive airway pressure therapy: evidence from different study models","author":"Bradicich","year":"2024","journal-title":"ERJ Open Res"},{"key":"10.1016\/j.sleep.2025.106607_bib73","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1111\/ene.12781","article-title":"Neurology and psychiatry: waking up to opportunities of sleep. : state of the art and clinical\/research priorities for the next decade","volume":"22","author":"Bassetti","year":"2015","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib74","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s11325-019-01921-4","article-title":"Excessive daytime sleepiness and fatigue in neurological disorders","volume":"24","author":"Maestri","year":"2020","journal-title":"Sleep Breath"},{"key":"10.1016\/j.sleep.2025.106607_bib75","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.neurol.2023.07.005","article-title":"Sleepiness in neurological disorders","volume":"179","author":"Dubessy","year":"2023","journal-title":"Rev Neurol (Paris)"},{"key":"10.1016\/j.sleep.2025.106607_bib76","doi-asserted-by":"crossref","first-page":"5561","DOI":"10.1007\/s00415-023-11911-y","article-title":"Daytime sleepiness and sleep quality in Charcot-Marie-Tooth disease","volume":"270","author":"Bellofatto","year":"2023","journal-title":"J Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib77","doi-asserted-by":"crossref","first-page":"4961","DOI":"10.1007\/s00415-022-11143-6","article-title":"Fatigue, sleepiness and depression in multiple sclerosis: defining the overlaps for a better phenotyping","volume":"269","author":"Sparasci","year":"2022","journal-title":"J Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib78","article-title":"Sleep disorders as both risk factors for, and a consequence of, stroke: a narrative review","author":"Mayer-Suess","year":"2023","journal-title":"Int J Stroke"},{"key":"10.1016\/j.sleep.2025.106607_bib79","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1310\/tsr1905-369","article-title":"Physical factors associated with fatigue after stroke: an exploratory study","volume":"19","author":"Hoang","year":"2012","journal-title":"Top Stroke Rehabil"},{"key":"10.1016\/j.sleep.2025.106607_bib80","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1177\/15459683241252826","article-title":"Presence of self-reported sleep alterations after stroke and their relationship with disability: a longitudinal study","volume":"38","author":"Rangel","year":"2024","journal-title":"Neurorehabilitation Neural Repair"},{"key":"10.1016\/j.sleep.2025.106607_bib81","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.smrv.2017.06.010","article-title":"Sleep disturbances increase the risk of dementia: a systematic review and meta-analysis","volume":"40","author":"Shi","year":"2018","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib82","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s10072-019-03785-8","article-title":"Excessive daytime sleepiness and its impact on quality of life in de novo Parkinson's disease","volume":"40","author":"Yoo","year":"2019","journal-title":"Neurol Sci"},{"key":"10.1016\/j.sleep.2025.106607_bib83","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1093\/sleep\/31.11.1601","article-title":"Validation of the fatigue severity scale in a Swiss cohort","volume":"31","author":"Valko","year":"2008","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib84","doi-asserted-by":"crossref","first-page":"zsz004","DOI":"10.1093\/sleep\/zsz004","article-title":"Sleepiness and sleepiness perception in patients with Parkinson's disease: a clinical and electrophysiological study","volume":"42","author":"Bargiotas","year":"2019","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib85","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1097\/WCO.0000000000000388","article-title":"Sleep-wake disturbances in the premotor and early stage of Parkinson's disease","volume":"29","author":"Bargiotas","year":"2016","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib86","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2023.101759","article-title":"Sleep and wakefulness disturbances in Parkinson's disease: a meta-analysis on prevalence and clinical aspects of REM sleep behavior disorder, excessive daytime sleepiness and insomnia","volume":"68","author":"Maggi","year":"2023","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib87","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.12673","article-title":"An overview of sleep and circadian dysfunction in Parkinson's disease","volume":"27","author":"Mantovani","year":"2018","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib88","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.parkreldis.2008.07.006","article-title":"Prevalence and clinical correlates of apathy in Parkinson's disease: a community-based study","volume":"15","author":"Pedersen","year":"2009","journal-title":"Parkinsonism Relat Disorders"},{"key":"10.1016\/j.sleep.2025.106607_bib89","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.5664\/jcsm.4044","article-title":"The underdiagnosis of sleep disorders in patients with multiple sclerosis","volume":"10","author":"Brass","year":"2014","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib90","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.smrv.2016.03.004","article-title":"Daytime sleepiness versus fatigue in patients with multiple sclerosis: a systematic review on the Epworth sleepiness scale as an assessment tool","volume":"32","author":"Popp","year":"2017","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib91","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1111\/ene.14984","article-title":"Contribution of sleep disturbances to fatigue in multiple sclerosis: a prospective study using clinical and polysomnographic parameters","volume":"28","author":"Riccitelli","year":"2021","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib92","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/ana.410390409","article-title":"Hypersomnia following paramedian thalamic stroke: a report of 12 patients","volume":"39","author":"Bassetti","year":"1996","journal-title":"Ann Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib93","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0092-8674(00)81973-X","article-title":"Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation","volume":"98","author":"Chemelli","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.sleep.2025.106607_bib94","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s00415-020-10140-x","article-title":"Progression of sleep disturbances in Parkinson's disease: a 5-year longitudinal study","volume":"268","author":"Xu","year":"2021","journal-title":"J Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib95","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.smrv.2005.12.003","article-title":"Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment","volume":"10","author":"Hornyak","year":"2006","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib96","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.13387","article-title":"European guideline and expert statements on the management of narcolepsy in adults and children","volume":"30","author":"Bassetti","year":"2021","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib97","doi-asserted-by":"crossref","first-page":"841","DOI":"10.2147\/NSS.S315556","article-title":"To nap or not to nap? A systematic review evaluating napping behavior in athletes and the impact on various measures of athletic performance","volume":"13","author":"Lastella","year":"2021","journal-title":"Nat Sci Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib98","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/mdc3.12063","article-title":"Sleep attacks in patients with Parkinson's disease on dopaminergic medications: a systematic review","volume":"1","author":"Yeung","year":"2014","journal-title":"Mov Disord Clin Pract"},{"key":"10.1016\/j.sleep.2025.106607_bib99","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/ibra.12024","article-title":"The role of intracerebral dopamine D1 and D2 receptors in sleep-wake cycles and general anesthesia","volume":"8","author":"Zhang","year":"2022","journal-title":"IBrain"},{"key":"10.1016\/j.sleep.2025.106607_bib100","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.5664\/jcsm.9326","article-title":"Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment","volume":"17","author":"Maski","year":"2021","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib101","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.14055","article-title":"Pharmacological management of narcolepsy in children and adolescents","volume":"33","author":"Plazzi","year":"2024","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib102","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1056\/NEJMoa2301940","article-title":"Oral orexin receptor 2 agonist in narcolepsy type 1","volume":"389","author":"Dauvilliers","year":"2023","journal-title":"N Engl J Med"},{"key":"10.1016\/j.sleep.2025.106607_bib103","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.smrv.2008.09.001","article-title":"Hypersomnia across mood disorders: a review and synthesis","volume":"13","author":"Kaplan","year":"2009","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib104","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jad.2018.09.016","article-title":"Prevalence and risk factors of excessive daytime sleepiness in major depression: a study with 703 individuals referred for polysomnography","volume":"243","author":"Hein","year":"2019","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sleep.2025.106607_bib105","doi-asserted-by":"crossref","first-page":"4510","DOI":"10.1210\/jc.2005-0035","article-title":"Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression","volume":"90","author":"Bixler","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.sleep.2025.106607_bib106","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jad.2014.05.060","article-title":"Prevalence and clinical correlates of co-occurring insomnia and hypersomnia symptoms in depression","volume":"167","author":"Soehner","year":"2014","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sleep.2025.106607_bib107","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jad.2024.09.163","article-title":"Sex differences in insomnia and hypersomnia complaints during major depressive episode: results from a national sample","volume":"369","author":"Geoffroy","year":"2025","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sleep.2025.106607_bib108","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1007\/s11126-021-09922-x","article-title":"Risk of excessive daytime sleepiness associated to major depression in adolescents","volume":"92","author":"Boz","year":"2021","journal-title":"Psychiatr Q"},{"key":"10.1016\/j.sleep.2025.106607_bib109","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1111\/jgs.16107","article-title":"The epidemiology of patient\u2010reported hypersomnia in persons with advanced age","volume":"67","author":"Miner","year":"2019","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.sleep.2025.106607_bib110","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.jad.2017.09.032","article-title":"Insomnia and hypersomnia in major depressive episode: prevalence, sociodemographic characteristics and psychiatric comorbidity in a population-based study","volume":"226","author":"Geoffroy","year":"2018","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sleep.2025.106607_bib111","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.5665\/sleep.2070","article-title":"Excessive sleepiness is predictive of cognitive decline in the elderly","volume":"35","author":"Jaussent","year":"2012","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib112","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.ncl.2012.08.018","article-title":"Psychiatric disorders and sleep","volume":"30","author":"Krystal","year":"2012","journal-title":"Neurol Clin"},{"key":"10.1016\/j.sleep.2025.106607_bib113","doi-asserted-by":"crossref","first-page":"A293","DOI":"10.1093\/sleep\/zsac079.665","article-title":"0669 The role of hypersomnolence in depression: results from A longitudinal study of the American general population","volume":"45","author":"Ohayon","year":"2022","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib114","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jad.2016.08.039","article-title":"Longitudinal associations of hypersomnolence and depression in the Wisconsin sleep cohort study","volume":"207","author":"Plante","year":"2017","journal-title":"J Affect Disord"},{"key":"10.1016\/j.sleep.2025.106607_bib115","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.smrv.2016.01.004","article-title":"Sleep propensity in psychiatric hypersomnolence: a systematic review and meta-analysis of multiple sleep latency test findings","volume":"31","author":"Plante","year":"2017","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib116","doi-asserted-by":"crossref","first-page":"713","DOI":"10.5664\/jcsm.9702","article-title":"Self-reported symptoms and objective measures in idiopathic hypersomnia and hypersomnia associated with psychiatric disorders: a prospective cross-sectional study","volume":"18","author":"Bu\u0161kov\u00e1","year":"2022","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib117","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.5664\/jcsm.8470","article-title":"Multimodal assessment increases objective identification of hypersomnolence in patients referred for multiple sleep latency testing","volume":"16","author":"Plante","year":"2020","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib118","doi-asserted-by":"crossref","first-page":"571","DOI":"10.5664\/jcsm.5694","article-title":"Subjective and objective measures of hypersomnolence demonstrate divergent associations with depression among participants in the Wisconsin sleep cohort study","volume":"12","author":"Plante","year":"2016","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib119","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.sleep.2019.11.1248","article-title":"Impaired neurobehavioral alertness quantified by the psychomotor vigilance task is associated with depression in the Wisconsin Sleep Cohort study","volume":"67","author":"Plante","year":"2020","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib120","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S0140-6736(22)01018-2","article-title":"Understanding and approaching excessive daytime sleepiness","volume":"400","author":"P\u00e9rez-Carbonell","year":"2022","journal-title":"The Lancet"},{"key":"10.1016\/j.sleep.2025.106607_bib121","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.sleep.2013.03.002","article-title":"Narcolepsy is complicated by high medical and psychiatric comorbidities: a comparison with the general population","volume":"14","author":"Ohayon","year":"2013","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib122","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.sleep.2014.01.015","article-title":"Delayed diagnosis of narcolepsy: characterization and impact","volume":"15","author":"Thorpy","year":"2014","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib123","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.sleep.2020.03.009","article-title":"Utility of measuring CSF hypocretin-1 level in patients with suspected narcolepsy","volume":"71","author":"Gabryelska","year":"2020","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib124","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.5664\/jcsm.10748","article-title":"A series of 7 cases of patients with narcolepsy with hypocretin deficiency without the HLA DQB1\u221706:02 allele","volume":"19","author":"Miano","year":"2023","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib125","article-title":"Unmet needs of patients with narcolepsy: perspectives on emerging treatment options","volume":"51","author":"Quinnell","year":"2015","journal-title":"Nat Sci Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib126","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.sleep.2008.05.010","article-title":"Chronobiology, excessive daytime sleepiness and depression: is there a link?","volume":"10","author":"Chellappa","year":"2009","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib127","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsz060","article-title":"Establishing the objective sleep phenotype in hypersomnolence disorder with and without comorbid major depression","volume":"42","author":"Plante","year":"2019","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib128","doi-asserted-by":"crossref","first-page":"150","DOI":"10.3390\/brainsci12020150","article-title":"Neurobiology of the orexin system and its potential role in the regulation of hedonic tone","volume":"12","author":"Katzman","year":"2022","journal-title":"Brain Sci"},{"key":"10.1016\/j.sleep.2025.106607_bib129","doi-asserted-by":"crossref","first-page":"2047","DOI":"10.5664\/jcsm.8750","article-title":"Developing a cognitive behavioral therapy for hypersomnia using telehealth: a feasibility study","volume":"16","author":"Ong","year":"2020","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib130","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2019.109763","article-title":"Improvement in hypersomnia with high frequency repetitive transcranial magnetic stimulation in depressed adolescents: preliminary evidence from an open-label study","volume":"97","author":"Sonmez","year":"2020","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.sleep.2025.106607_bib131","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s10198-013-0491-2","article-title":"Health, social and economic consequences of hypersomnia: a controlled national study from a national registry evaluating the societal effect on patients and their partners","volume":"15","author":"Jennum","year":"2014","journal-title":"Eur J Health Econ"},{"key":"10.1016\/j.sleep.2025.106607_bib132","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2023.101854","article-title":"The economic cost of obstructive sleep apnea: a systematic review","volume":"72","author":"Alak\u00f6rkk\u00f6","year":"2023","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib133","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2020.101275","article-title":"The economic and societal burden of excessive daytime sleepiness in patients with obstructive sleep apnea","volume":"51","author":"L\u00e9ger","year":"2020","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.sleep.2025.106607_bib134","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.sleep.2021.05.010","article-title":"Socioeconomic and humanistic burden of illness of excessive daytime sleepiness severity associated with obstructive sleep apnoea in the European Union 5","volume":"84","author":"Jennum","year":"2021","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib135","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/sleep\/34.3.363","article-title":"Excessive daytime sleepiness is associated with increased health care utilization among patients referred for assessment of OSA","volume":"34","author":"Ronksley","year":"2011","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib136","doi-asserted-by":"crossref","first-page":"401","DOI":"10.5664\/jcsm.5594","article-title":"The humanistic and economic burden of narcolepsy","volume":"12","author":"Flores","year":"2016","journal-title":"J Clin Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib137","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsy083","article-title":"The economic cost of inadequate sleep","volume":"41","author":"Hillman","year":"2018","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib138","doi-asserted-by":"crossref","first-page":"zsab132","DOI":"10.1093\/sleep\/zsab132","article-title":"The social and economic cost of sleep disorders","volume":"44","author":"Streatfeild","year":"2021","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib139","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.sleh.2017.11.007","article-title":"Burden of disease due to sleep duration and sleep problems in the elderly","volume":"4","author":"Lubetkin","year":"2018","journal-title":"Sleep Health"},{"key":"10.1016\/j.sleep.2025.106607_bib140","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.sleep.2011.07.014","article-title":"Quality of life in patients with narcolepsy with cataplexy, narcolepsy without cataplexy, and idiopathic hypersomnia without long sleep time: comparison between patients on psychostimulants, drug-na\u00efve patients and the general Japanese population","volume":"13","author":"Ozaki","year":"2012","journal-title":"Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib141","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1080\/15402002.2021.2021202","article-title":"A longitudinal study of insomnia, daytime sleepiness, and academic performance in Chinese adolescents","volume":"20","author":"Zhang","year":"2022","journal-title":"Behav Sleep Med"},{"key":"10.1016\/j.sleep.2025.106607_bib142","doi-asserted-by":"crossref","first-page":"21209","DOI":"10.1073\/pnas.2004535117","article-title":"Sleepiness, sleep duration, and human social activity: an investigation into bidirectionality using longitudinal time-use data","volume":"117","author":"Holding","year":"2020","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.sleep.2025.106607_bib143","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1111\/jora.12670","article-title":"Sleepy and secluded: sleep disturbances are associated with connectedness in early adolescent social networks","volume":"32","author":"Palmer","year":"2022","journal-title":"J Res Adolesc"},{"key":"10.1016\/j.sleep.2025.106607_bib144","first-page":"11","article-title":"Why sleep matters-the economic costs of insufficient sleep: a cross-country comparative analysis","volume":"6","author":"Hafner","year":"2017","journal-title":"Rand Health Q"},{"key":"10.1016\/j.sleep.2025.106607_bib145","doi-asserted-by":"crossref","first-page":"A37","DOI":"10.1093\/sleep\/zsab072.088","article-title":"089 Impact of a single sleep education session on beliefs and attitudes among people with excessive daytime sleepiness: a pilot study","volume":"44","author":"Wills","year":"2021","journal-title":"Sleep"},{"key":"10.1016\/j.sleep.2025.106607_bib146","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s40675-023-00250-z","article-title":"The evolving diagnosis and classification of CNS hypersomnolence disorders","volume":"9","author":"Lammers","year":"2023","journal-title":"Curr Sleep Med Rep"},{"key":"10.1016\/j.sleep.2025.106607_bib147","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1159\/000335363","article-title":"Prevalence of sleep disturbances in mild cognitive impairment and dementing disorders: a multicenter Italian clinical cross-sectional study on 431 patients","volume":"33","author":"Guarnieri","year":"2012","journal-title":"Dement Geriatr Cogn Disord"},{"key":"10.1016\/j.sleep.2025.106607_bib148","doi-asserted-by":"crossref","DOI":"10.1016\/j.yebeh.2020.107023","article-title":"Subjective and objective hypersomnia highly prevalent in adults with epilepsy","volume":"106","author":"Grigg-Damberger","year":"2020","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.sleep.2025.106607_bib149","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.seizure.2006.02.018","article-title":"Sleep-wake habits and disorders in a series of 100 adult epilepsy patients--a prospective study","volume":"15","author":"Khatami","year":"2006","journal-title":"Seizure"},{"key":"10.1016\/j.sleep.2025.106607_bib150","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1007\/s00415-018-8949-x","article-title":"Coexisting narcolepsy (with and without cataplexy) and multiple sclerosis : six new cases and a literature review","volume":"265","author":"Kallweit","year":"2018","journal-title":"J Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib151","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2024.1389949","article-title":"Excessive daytime sleepiness in myotonic dystrophy: a narrative review","volume":"15","author":"Hoxhaj","year":"2024","journal-title":"Front Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib152","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.pjnns.2017.01.007","article-title":"Excessive daytime sleepiness in a patient with coexisting myotonic dystrophy type 1, myasthenia gravis and Graves' disease","volume":"51","author":"Kapica-Topczewska","year":"2017","journal-title":"Neurol Neurochir Pol"},{"key":"10.1016\/j.sleep.2025.106607_bib153","doi-asserted-by":"crossref","DOI":"10.1212\/NXI.0000000000001064","article-title":"Fatigue in survivors of autoimmune encephalitis","volume":"8","author":"Diaz-Arias","year":"2021","journal-title":"Neurol Neuroimmunol Neuroinflammation"},{"key":"10.1016\/j.sleep.2025.106607_bib154","doi-asserted-by":"crossref","first-page":"5429","DOI":"10.1007\/s10072-024-07652-z","article-title":"Distinctive sleep complaints and polysomnographic findings in antibody subgroups of autoimmune limbic encephalitis","volume":"45","author":"K\u00fc\u00e7\u00fckali","year":"2024","journal-title":"Neurol Sci"},{"key":"10.1016\/j.sleep.2025.106607_bib155","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/s10194-017-0743-0","article-title":"Association of excessive daytime sleepiness with migraine and headache frequency in the general population","volume":"18","author":"Stavem","year":"2017","journal-title":"J Headache Pain"},{"key":"10.1016\/j.sleep.2025.106607_bib156","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1365-2869.2011.00943.x","article-title":"Severe fatigue in narcolepsy with cataplexy","volume":"21","author":"Droogleever Fortuyn","year":"2012","journal-title":"J Sleep Res"},{"key":"10.1016\/j.sleep.2025.106607_bib157","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jocn.2024.01.007","article-title":"Association between cytokines and fatigue in patients with type 1 narcolepsy","volume":"120","author":"Yang","year":"2024","journal-title":"J Clin Neurosci"},{"key":"10.1016\/j.sleep.2025.106607_bib158","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1159\/000228261","article-title":"Excessive Daytime sleepiness in idiopathic restless legs syndrome: characteristics and evolution under dopaminergic treatment","volume":"62","author":"Kallweit","year":"2009","journal-title":"Eur Neurol"},{"key":"10.1016\/j.sleep.2025.106607_bib159","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3390\/biology5010011","article-title":"Sleep-wake regulation and its impact on working memory performance: the role of adenosine","volume":"5","author":"Reichert","year":"2016","journal-title":"Biology"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945725002825?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945725002825?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:50:23Z","timestamp":1778853023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945725002825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":159,"alternative-id":["S1389945725002825"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2025.106607","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hypersomnolence in focus: a white paper of the 6th Think Tank World Sleep Forum","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2025.106607","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"106607"}}