{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T01:54:48Z","timestamp":1775181288303,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Sleep Medicine"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.sleep.2026.108882","type":"journal-article","created":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T00:23:10Z","timestamp":1772583790000},"page":"108882","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Antidepressant withdrawal-induced de novo restless legs syndrome: a case report"],"prefix":"10.1016","volume":"142","author":[{"given":"Elza A.","family":"Balian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narine M.","family":"Nadryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilit G.","family":"Atabekyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haykuhi A.","family":"Hovakimyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaruhi D.","family":"Tavadyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3098-2135","authenticated-orcid":false,"given":"Samson G.","family":"Khachatryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.sleep.2026.108882_bib1","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.sleep.2014.03.025","article-title":"Restless legs Syndrome\/Willis-Ekbom disease diagnostic criteria: updated international restless legs syndrome study group (IRLSSG) consensus criteria\u2013history, rationale, description, and significance","volume":"15","author":"Allen","year":"2014","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.sleep.2026.108882_bib2","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1038\/s41572-021-00311-z","article-title":"Restless legs syndrome","volume":"7","author":"Manconi","year":"2021","journal-title":"Nat Rev Dis Primers"},{"issue":"7","key":"10.1016\/j.sleep.2026.108882_bib3","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1177\/1060028018760296","article-title":"Drug-induced restless legs syndrome","volume":"52","author":"Patatanian","year":"2018","journal-title":"Ann Pharmacother"},{"issue":"1","key":"10.1016\/j.sleep.2026.108882_bib4","doi-asserted-by":"crossref","first-page":"79","DOI":"10.5664\/jcsm.27716","article-title":"Pharmacologically induced\/exacerbated restless legs syndrome, periodic limb movements of sleep, and REM behavior disorder\/REM sleep without atonia: literature review, qualitative scoring, and comparative analysis","volume":"6","author":"Hoque","year":"2010","journal-title":"J Clin Sleep Med"},{"issue":"2","key":"10.1016\/j.sleep.2026.108882_bib5","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1592\/phco.28.2.271","article-title":"Restless legs syndrome induced by escitalopram: case report and review of the literature","volume":"28","author":"Page","year":"2008","journal-title":"Pharmacotherapy"},{"issue":"2","key":"10.1016\/j.sleep.2026.108882_bib6","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/mds.870090211","article-title":"Withdrawal akathisia: case reports and a proposed classification of chronic akathisia","volume":"9","author":"Lang","year":"1994","journal-title":"Mov Disord"},{"key":"10.1016\/j.sleep.2026.108882_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.euroneuro.2022.10.005","article-title":"Antidepressant discontinuation syndrome: a state-of-the-art clinical review","volume":"66","author":"Fornaro","year":"2023","journal-title":"Eur Neuropsychopharmacol"},{"issue":"1","key":"10.1016\/j.sleep.2026.108882_bib8","first-page":"56","article-title":"A case of Akathisia induced by escitalopram: case report & review of literature","volume":"9","author":"Basu","year":"2014","journal-title":"Adv Contracept Deliv Syst (CDS)"},{"issue":"11","key":"10.1016\/j.sleep.2026.108882_bib9","first-page":"1286","article-title":"Imipramine withdrawal: an Akathisia-Like syndrome","volume":"130","author":"Sathananthan","year":"1973","journal-title":"Aust J Pharm"},{"issue":"2","key":"10.1016\/j.sleep.2026.108882_bib10","first-page":"455","article-title":"Antidepressant withdrawal reactions","volume":"56","author":"Wolfe","year":"1997","journal-title":"Am Fam Physician"},{"issue":"7","key":"10.1016\/j.sleep.2026.108882_bib11","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1176\/ajp.143.7.938a","article-title":"Propranolol in the treatment of restless legs syndrome induced by imipramine withdrawal","volume":"143","author":"Ginsberg","year":"1986","journal-title":"Am J Psychiatr"},{"issue":"2","key":"10.1016\/j.sleep.2026.108882_bib12","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/00004850-199400920-00011","article-title":"Mechanisms of the development of trazodone withdrawal symptoms","volume":"9","author":"Otani","year":"1994","journal-title":"Int Clin Psychopharmacol"},{"issue":"3","key":"10.1016\/j.sleep.2026.108882_bib13","first-page":"2080","article-title":"Kappa opioid receptors reduce serotonin uptake and escitalopram efficacy in the Mouse substantia Nigra pars reticulata","volume":"24","author":"West","year":"2023","journal-title":"Indian J Manag Sci"},{"issue":"9","key":"10.1016\/j.sleep.2026.108882_bib14","doi-asserted-by":"crossref","first-page":"769","DOI":"10.2165\/11204760-000000000-00000","article-title":"Escitalopram: a review of its use in the management of major depressive disorder in adults","volume":"24","author":"Garnock-Jones","year":"2010","journal-title":"CNS Drugs"},{"issue":"5","key":"10.1016\/j.sleep.2026.108882_bib15","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/syn.20853","article-title":"Effects of S\u2010citalopram, citalopram, and R\u2010citalopram on the firing patterns of dopamine neurons in the ventral tegmental area, N \u2010Methyl\u2010 D \u2010aspartate receptor\u2010mediated transmission in the medial prefrontal cortex and cognitive function in the rat","volume":"65","author":"Schilstr\u00f6m","year":"2011","journal-title":"Synapse"},{"issue":"6","key":"10.1016\/j.sleep.2026.108882_bib16","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3390\/biom10060880","article-title":"The effect of escitalopram on central serotonergic and dopaminergic systems in patients with cervical dystonia, and its relationship with clinical treatment effects: a double-blind placebo-controlled trial","volume":"10","author":"Zoons","year":"2020","journal-title":"Biomolecules"}],"container-title":["Sleep Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945726001218?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1389945726001218?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T01:17:03Z","timestamp":1775179023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1389945726001218"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":16,"alternative-id":["S1389945726001218"],"URL":"https:\/\/doi.org\/10.1016\/j.sleep.2026.108882","relation":{},"ISSN":["1389-9457"],"issn-type":[{"value":"1389-9457","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antidepressant withdrawal-induced de novo restless legs syndrome: a case report","name":"articletitle","label":"Article Title"},{"value":"Sleep Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.sleep.2026.108882","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108882"}}